Fren_00040 : CDS information

Location

Organism	Streptomyces roseofulvus
Strain	AK24158
Entry name	Frenolicin
Contig	AF058302
Start / Stop / Direction	5,768 / 7,342 / + [in whole cluster] 5,768 / 7,342 / + [in contig]
Location	5768..7342 [in whole cluster] 5768..7342 [in contig]
Type	CDS
Length	1,575 bp (524 aa)

Annotation

Category	4.3 transport
Product	putative ABC transporter ATP-binding protein
Product (GenBank)	ATPase component of putative ABC transporter
Gene
Gene (GenBank)	frnD
EC number
Keyword
Note
Note (GenBank)	FrnD; similar to Streptomyces peucetius DRRA
Reference	ACC O68910 comment "Analysis of a 27 kb region of Streptomyces roseofulvus containing genes for frenolicin biosynthesis." 論文として報告があるのは10.2kbp領域のみ[PMID:8181754]。このORFはその範囲外でGenBank登録AF058302に由来する。
Related Reference	ACC P0AAG0 PmId [7536291] The dipeptide permease of Escherichia coli closely resembles other bacterial transport systems and shows growth-phase-dependent expression. (Mol Microbiol. , 1994) [16905647] The housekeeping dipeptide permease is the Escherichia coli heme transporter and functions with two optional peptide binding proteins. (Proc Natl Acad Sci U S A. , 2006) comment >N-terminal Blast id35.46%, 8e-43 E.coli_dppD Dipeptide transport ATP-binding protein DppD --- [PMID:7536291](1994) abstract ２つまたは３つのL-アミノ酸から成るpeptideをtransportするdipeptide permease(Dpp)をコードするdpp locusのシークエンス。 dppABCDEのoperonを編成。 -- [PMID:16905647](2006) E.coli K12はヘム鉄を使用するため、dipeptide inner membrane ATP-binding cassette transporter (DppBCDF)と、2つのperiplasmic binding proteins: MppA or DppAのどちらかを要求する。
	ACC P37313 PmId [7536291] The dipeptide permease of Escherichia coli closely resembles other bacterial transport systems and shows growth-phase-dependent expression. (Mol Microbiol. , 1994) [16905647] The housekeeping dipeptide permease is the Escherichia coli heme transporter and functions with two optional peptide binding proteins. (Proc Natl Acad Sci U S A. , 2006) comment >C-terminal Blast id40.16%, 1e-41 E.coli_dppF(dppE) Dipeptide transport ATP-binding protein DppF -- [PMID:7536291](1994) abstract ２つまたは３つのL-アミノ酸から成るpeptideをtransportするdipeptide permease(Dpp)をコードするdpp locusのシークエンス。 dppABCDEのoperonを編成。 -- [PMID:16905647](2006) E.coli K12はヘム鉄を使用するため、dipeptide inner membrane ATP-binding cassette transporter (DppBCDF)と、2つのperiplasmic binding proteins: MppA or DppAのどちらかを要求する。
	ACC O50263 PmId [9987134] Mannopinic acid and agropinic acid catabolism region of the octopine-type Ti plasmid pTi15955. (Mol Microbiol. , 1999) comment 265th(O50263) 37%, 3e-91 Rhizobium radiobacter(Plasmid Ti)_agaD AgaD AgaC, AgaB and AgaDはagropinic acid uptake systemに関与。

Sequence

>putative ABC transporter ATP-binding protein [ATPase component of putative ABC transporter]
MTPADKPTDERSPVLDLSGVSVAYGTRTVLHGIDLRLAPGQVLAVLGASGSGKSTLAQAA
LGLLPPGGRVTAGRVTVAGHDITALAPHRLRALRGTVTGLVPQDQAVSLDPLVRVGAQVT
ETLRAHRLEDRREAARRAVPLLGEAGIEAPGPLARAYPHALSGGQRQRVLVAGAFAARPP
LVVADEPTSALDATVRRRVMDRFAALVAAHGTAVLLVTHDFRLARERADQVAVLADGRLV
ESGPAARVLDRPAHPYTRRLTGAGRRVAARGTAPRASGTPVVRARDLVKEYRRDGRRVRA
VDGVGFTVREGEFFALVGESGSGKSTTARLVTGLTAPTSGAVEHAPAPVRPQLVQQSPYA
AFDPRWTVRRIVEEPLRARHVPGARRRARLRELLALVGLDEELLARRPRELSGGQRQRVA
LARALAPEPRLLVCGEPVAALDPVARERVVHLLERLRAELGLTCLFVSHELDVVRRLCGR
VAVMRGGRLLESGPVGEVLSAPSQPYTRALLAAEAGPSDTPGAG

>putative ABC transporter ATP-binding protein [ATPase component of putative ABC transporter]
ATGACCCCGGCGGACAAGCCGACCGACGAGCGCTCACCTGTCCTGGACCTCAGTGGTGTC
AGCGTCGCCTACGGGACGCGCACCGTGCTGCACGGCATCGATCTGCGCCTCGCGCCGGGG
CAGGTGCTCGCGGTGCTCGGCGCCTCGGGTTCCGGCAAGAGCACCCTCGCGCAGGCGGCT
CTCGGCCTCCTGCCCCCCGGCGGCCGGGTGACGGCAGGGCGCGTCACGGTCGCCGGGCAC
GACATCACCGCGCTCGCGCCGCACCGGCTGCGCGCGCTGCGCGGCACGGTCACCGGACTC
GTGCCGCAGGACCAGGCGGTCTCCCTCGACCCCCTCGTCCGCGTCGGCGCGCAGGTCACC
GAGACGCTGCGCGCCCATCGCCTGGAGGACCGCCGCGAGGCCGCCCGGCGCGCCGTGCCC
TTGCTCGGCGAGGCGGGGATCGAGGCCCCCGGGCCGCTCGCCCGCGCCTACCCGCACGCG
CTCTCCGGCGGCCAACGCCAACGCGTCCTCGTCGCCGGGGCCTTCGCGGCCCGCCCCCCG
CTGGTCGTCGCCGACGAGCCGACGAGCGCGCTCGACGCGACCGTGCGGCGCCGGGTCATG
GACCGCTTCGCCGCCCTCGTCGCCGCGCACGGCACGGCCGTCCTCCTCGTCACCCACGAC
TTCCGGCTCGCGAGGGAACGCGCCGACCAGGTCGCCGTCCTCGCGGACGGCCGTCTCGTG
GAGAGCGGCCCCGCCGCACGGGTCCTCGACCGGCCCGCCCACCCGTACACCCGCCGCCTC
ACGGGGGCCGGCCGCCGCGTGGCCGCACGGGGCACGGCGCCGCGCGCGTCGGGCACCCCC
GTGGTGCGCGCCCGCGACCTCGTCAAGGAGTACCGGCGGGACGGGCGGCGGGTGCGCGCC
GTGGACGGGGTCGGCTTCACGGTCCGCGAAGGCGAGTTCTTCGCCCTCGTCGGCGAGTCG
GGCTCGGGCAAGTCCACGACCGCCCGGCTCGTGACGGGTCTGACCGCGCCCACGTCGGGC
GCGGTGGAGCACGCGCCCGCTCCGGTGCGGCCCCAGCTCGTCCAGCAGAGCCCGTACGCG
GCCTTCGACCCGCGCTGGACCGTGCGCCGCATCGTGGAGGAGCCGCTGCGGGCGCGGCAC
GTGCCCGGGGCGCGGCGGCGGGCGCGGCTGCGCGAACTGCTCGCGCTCGTCGGCCTCGAC
GAGGAGCTGCTCGCGCGGCGGCCCCGGGAGCTGTCCGGCGGGCAGCGGCAGCGGGTGGCG
CTCGCCCGCGCGCTCGCCCCGGAACCGCGCCTGCTCGTGTGCGGCGAACCCGTCGCCGCC
CTCGACCCCGTCGCGCGCGAGCGCGTCGTCCACCTCCTGGAGCGGCTGCGGGCGGAGCTG
GGCCTCACGTGCCTCTTCGTCTCCCACGAGCTGGACGTCGTGCGGCGGTTGTGCGGTCGC
GTCGCCGTCATGCGGGGCGGGCGGCTACTGGAGAGCGGACCGGTGGGGGAGGTGCTGTCG
GCGCCCTCGCAGCCGTACACGCGGGCGCTGCTCGCCGCGGAGGCGGGCCCTTCCGACACG
CCCGGAGCGGGGTGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR003439 ABC transporter-like (Domain) PS50893 ABC_TRANSPORTER_2 PF00005 ABC_tran IPR003593 AAA+ ATPase domain (Domain) SM00382 AAA IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal (Domain) PF08352 oligo_HPY IPR017871 ABC transporter, conserved site (Conserved_site) PS00211 ABC_TRANSPORTER_1
SignalP	Bacteria, Gram-negative
TMHMM	No significant hit

Fren_00030 Fren_00050