Medem_00020 : CDS information

Location

Organism	Streptomyces sp.
Strain	AM-7161
Entry name	Medermycin
Contig	AB103463
Start / Stop / Direction	1,181 / 648 / - [in whole cluster] 1,181 / 648 / - [in contig]
Location	complement(648..1181) [in whole cluster] complement(648..1181) [in contig]
Type	CDS
Length	534 bp (177 aa)

Annotation

Category
Product
Product (GenBank)	adenylylsulfate kinase
Gene
Gene (GenBank)	ORF Q
EC number
Keyword
Note	It is supposed that this ORF is not involved in medermycin biosynthesis.
Note (GenBank)	GTG start codon
Reference	ACC Q7WT40 PmId [12855716] Cloning, sequencing and heterologous expression of the medermycin biosynthetic gene cluster of Streptomyces sp. AM-7161: towards comparative analysis of the benzoisochromanequinone gene clusters. (Microbiology. , 2003) comment ORF Q: No relation?

Sequence

>[adenylylsulfate kinase]
MTGATIWLTGLPSAGKTTIAYELAGRLRDEGHAVEILDGDEIREFLSAGLGFTREDRHTN
VQRIGFVAELLASHGVKVLVPVIAPYNDSREAVRKRHQAEGTAFVEVHVATPVDVCSVRD
VKGLYAKQAAGEISGLTGVDDPYEAPENPDLRIESQNQTVQESAAQLHALLTERGLL

>[adenylylsulfate kinase]
GTGACCGGTGCCACCATCTGGCTCACCGGCCTGCCGAGCGCCGGGAAGACCACCATCGCG
TACGAGCTGGCCGGCCGCCTCCGCGACGAGGGCCACGCCGTCGAGATCCTCGACGGCGAC
GAGATCCGCGAGTTCCTCTCGGCGGGCCTCGGCTTCACCCGCGAGGACCGGCACACCAAC
GTGCAGCGGATCGGCTTCGTCGCCGAGCTGCTCGCCTCGCACGGCGTGAAGGTCCTGGTC
CCGGTCATCGCCCCGTACAACGACAGCCGCGAGGCGGTCCGCAAGCGCCACCAGGCCGAG
GGCACCGCCTTCGTCGAGGTGCACGTGGCCACCCCCGTGGACGTCTGCTCCGTCCGCGAC
GTGAAGGGCCTCTACGCCAAGCAGGCCGCGGGCGAGATCAGCGGCCTCACCGGCGTCGAC
GACCCGTACGAGGCGCCCGAGAACCCCGATCTGCGGATCGAGTCCCAGAACCAGACCGTG
CAGGAGTCCGCGGCGCAGCTCCACGCGCTGCTCACCGAGAGGGGTCTGCTGTGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR002891 Adenylylsulphate kinase (Family) TIGR00455 ApsK PF01583 APS_kinase
SignalP	No significant hit
TMHMM	No significant hit

Medem_00010 Medem_00030