Sch475_00100 Sch475_00100   Sch475_00120 Sch475_00120

Sch475_00110 : CDS information

close this sectionLocation

Organism
StrainSCC-2136
Entry nameSch 47554
Contig
Start / Stop / Direction16,247 / 14,577 / - [in whole cluster]
16,247 / 14,577 / - [in contig]
Locationcomplement(14577..16247) [in whole cluster]
complement(14577..16247) [in contig]
TypeCDS
Length1,671 bp (556 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category5.1 general function
Productputative glucose-6-phosphate isomerase
putative phosphoglucose isomerase
putative phosphohexose isomerase
Product (GenBank)glucose-6-phosphate isomerase
GeneschA11
pgi
Gene (GenBank)schA11
EC number5.3.1.9
Keyword
  • PPP
Note
  • The N-terminal position was modified from original INSDC entry.
Note (GenBank)
Reference
ACC
PmId
[17085966] Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: cloning, sequencing, and characterization. (Mol Cells. , 2006)
comment
angucyclines Sch 47554 and Sch 47555の生合成に関連したentire gene clusterの
クローニング、シークエンス、配列解析からの特徴づけ。

SchA11(467aa): Glucose-6-phosphate isomerase

本文コメントなし。
Related Reference
ACC
P96803
PmId
[9098072] ( , )
comment
Blast 73rd, id59%, 1e-172
Mycobacterium smegmatis_pgi
Glucose-6-phosphate isomerase(EC 5.3.1.9)

glucose要求株を分離して解析したところpgi geneのdeletionがありPgi activityも非常に抑制されているが、プラスミドによるpgi geneの導入で補完される。
ACC
P0A6T1
PmId
comment
Blast 315th, id51%, 1e-154
E.coli_pgi
Glucose-6-phosphate isomerase(EC 5.3.1.9)

E.coli K-12 MG1655strainで実験している。

Escherichia coli strain Pgi-UdhA, a mutant of the strain MG1655は、pgi gene and the udhA geneの不全のためグルコースで生育不可能。古細菌または微生物のpgi, cpgi or pgi/pmiをプラスミド導入すると、生育回復。

close this sectionSequence

selected fasta
>putative glucose-6-phosphate isomerase [glucose-6-phosphate isomerase]
MPDTPPSEPRTPRLTRRPEWTALEDHRAGPLLHPQLRELFAADPERASRYTVRVGDLRID
YSKHLITDETLALLQELATATDVFGLRDAMFRGERINVTEGRAVLHTALRAPLEAVVEVA
GENVVPKVHAVLDKMSDFAEQVRSGKWTGHTGRRIRNVVNIGIGGSDLGPAMAYEALRAF
TDRDLTVRFVSNVDGADLHEAVRDLDPAETLFVVASKTFTTIETITNATSARTWLLAGLG
GESEAVARHFVALSTNVEKVADFGIDTANMFEFWDWVGGRYSFDSAIGLSLMIAIGPDRF
REMLDGFHLVDEHFRTAPAESNAPLLLGLLGVWYGDFFGAQSHAVLPYSHYLSKFTAYLQ
QLDMESNGKSVDREGHPVEWQTGPVVWGTPGTNGQHAYYQLLPPGHEDDPGRSDRLRQPV
DELGAELAAQHDLLMANLFAQGQALAFGKTADEVRAEGVPEEQVPHRTFRGNHPTTTVLA
AELTPSVLGQLIALYEHKVFVQGAIWNIDSFDQWGVELGKVLAKRVEPALTEGADVPGLD
PSTAALVATYRTLRKK
selected fasta
>putative glucose-6-phosphate isomerase [glucose-6-phosphate isomerase]
GTGCCTGACACGCCTCCGTCCGAGCCCCGGACGCCCAGGCTCACCCGTCGCCCCGAGTGG
ACGGCCCTGGAGGACCACCGCGCGGGCCCGCTCCTCCATCCGCAGCTGCGCGAGCTGTTC
GCCGCGGACCCGGAGCGCGCCTCGCGCTACACCGTGCGGGTCGGTGACCTGCGCATCGAC
TACTCCAAGCACCTGATCACCGACGAGACGCTCGCGCTGCTCCAGGAACTCGCCACCGCC
ACCGACGTGTTCGGGCTGCGGGACGCGATGTTCCGCGGCGAGCGGATCAACGTCACCGAG
GGGCGGGCCGTGCTGCACACCGCGCTGCGCGCCCCGCTCGAAGCGGTCGTCGAGGTCGCC
GGCGAGAACGTCGTGCCGAAGGTGCACGCCGTGCTCGACAAGATGTCGGACTTCGCCGAG
CAGGTCCGCTCCGGCAAGTGGACCGGCCACACGGGCAGGCGCATCCGCAATGTCGTCAAC
ATCGGCATCGGCGGCTCCGACCTCGGTCCGGCGATGGCGTACGAGGCCCTGCGCGCCTTC
ACCGACCGCGATCTGACGGTCCGCTTCGTGTCCAACGTGGACGGGGCCGACCTGCACGAG
GCCGTCCGCGACTTGGACCCGGCGGAGACGCTGTTCGTCGTCGCCTCGAAGACGTTCACG
ACCATCGAGACGATCACCAATGCGACCTCGGCGCGGACCTGGCTGCTCGCCGGTCTCGGC
GGTGAGTCCGAGGCCGTGGCCCGGCACTTCGTGGCGCTGTCGACGAACGTCGAGAAGGTC
GCGGACTTCGGTATCGACACGGCCAACATGTTCGAGTTCTGGGACTGGGTCGGCGGCCGT
TACTCGTTCGACTCGGCGATCGGTCTGTCGCTGATGATCGCGATCGGCCCGGACCGCTTC
CGGGAGATGCTCGACGGCTTCCACCTCGTCGACGAGCACTTCAGGACCGCGCCCGCCGAG
TCCAACGCGCCTTTGCTGCTCGGCCTGTTGGGCGTCTGGTACGGCGACTTCTTCGGCGCC
CAGTCGCACGCGGTGCTGCCGTACTCGCACTACCTGTCCAAGTTCACCGCGTACTTGCAG
CAGCTCGACATGGAGTCCAACGGCAAGTCCGTCGACCGCGAGGGACACCCGGTCGAGTGG
CAGACCGGGCCCGTCGTGTGGGGCACGCCCGGCACCAACGGCCAGCACGCGTACTACCAG
TTGCTCCCACCAGGGCACGAAGACGATCCCGGCCGATCTGATCGGCTTCGTCAACCGGTC
GACGAGCTGGGTGCCGAACTCGCCGCCCAGCACGACCTGTTGATGGCGAACCTCTTCGCC
CAGGGCCAGGCCCTCGCGTTCGGCAAGACCGCCGACGAGGTACGCGCCGAGGGGGTGCCC
GAGGAGCAGGTCCCGCACCGCACCTTCCGCGGCAACCACCCCACGACCACGGTCCTGGCC
GCCGAGTTGACCCCGTCGGTGCTCGGCCAGCTCATCGCCCTCTACGAGCACAAGGTGTTC
GTGCAGGGCGCGATCTGGAACATCGACTCCTTCGACCAGTGGGGCGTCGAGCTCGGCAAG
GTCCTCGCCAAGCGCGTCGAACCCGCCCTCACCGAGGGCGCCGACGTCCCCGGTCTCGAT
CCCTCCACCGCCGCCCTCGTGGCCACGTACCGCACTCTGCGAAAGAAGTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR001672 Phosphoglucose isomerase (PGI) (Family)
[158-177] 1.5e-53 PR00662 [271-289] 1.5e-53 PR00662 [348-369] 1.5e-53 PR00662 [471-489] 1.5e-53 PR00662 [489-503] 1.5e-53 PR00662 [503-516] 1.5e-53 PR00662
PR00662   G6PISOMERASE
[17-553] 138.904 PS51463
PS51463   P_GLUCOSE_ISOMERASE_3
[54-530] 39.573 MF_00473
MF_00473   G6P_isomerase
[60-547] 1.1e-184 PF00342
PF00342   PGI
IPR018189 Phosphoglucose isomerase, conserved site (Conserved_site)
[503-520] PS00174
PS00174   P_GLUCOSE_ISOMERASE_2
[275-288] PS00765
PS00765   P_GLUCOSE_ISOMERASE_1
IPR023096 Phosphoglucose isomerase, C-terminal (Domain)
[508-555] 1.7e-17 G3DSA:1.10.1390.10
G3DSA:1.10.1390.10   no description
SignalP No significant hit
TMHMM No significant hit
Sch475_00100 Sch475_00100   Sch475_00120 Sch475_00120
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