C1027_00390 C1027_00390   C1027_00405 C1027_00405

C1027_00400 : CDS information

close this sectionLocation

Organism
StrainC-1027
Entry nameC-1027
Contig
Start / Stop / Direction52,336 / 51,416 / - [in whole cluster]
52,336 / 51,416 / - [in contig]
Locationcomplement(51416..52336) [in whole cluster]
complement(51416..52336) [in contig]
TypeCDS
Length921 bp (306 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category5.1 general function
Productputative oxidoreductase
Product (GenBank)oxidoreductase
GenesgcN
Gene (GenBank)
EC number
Keyword
Note
Note (GenBank)
  • ORF32
Reference
ACC
PmId
[12183628] Biosynthesis of the enediyne antitumor antibiotic C-1027. (Science. , 2002)
comment
C-1027の生合成遺伝子クラスターの報告

Fig.2にてcluster内に表示されているのみ
特にふれていない。
Related Reference
ACC
Q96NR8
PmId
comment
Human_ RDH12
Retinol dehydrogenase 12

RDH11,12,14の活性を確認している。なおRDH13では活性を確認できていない。

RDH11,14もこのORF(C1027_00400)と相同性を示す。
Family/Domain
FD
IPR002198
comment
[IPR002198] Short-chain dehydrogenase/reductase SDR (Family)

close this sectionSequence

selected fasta
>putative oxidoreductase [oxidoreductase]
MRTRRRWSAADVPDRTGTTAVVTGASSGIGLHLAQELARHGAHVVLAVRDPDRGVAAAAR
IQSRVPSAQLTVRRLDLSRLASVRAGAEELRDRFPRIHLLVNNAGVMWTDRARTPDGHEL
QFATNHLGHFALTGLLLDSLRAAPGARVVTISSYLHRLGRIDFSDLHGERRYSRYRAYNQ
SKLANLMFALELHHRLAESGAELASLAAHPGLTATGLGRDFPAPVRRLGSPLAPLFLQPA
AAGMLPGLRAATDPGARGGEFYGPLGVTETRGAPGLVRPGGAAVDPRARRRLWEESEHLT
GVRLRP
selected fasta
>putative oxidoreductase [oxidoreductase]
ATGAGAACGCGGCGACGCTGGAGCGCCGCCGATGTCCCGGACCGTACCGGAACCACCGCG
GTGGTCACCGGTGCCAGCTCCGGCATCGGACTGCACCTGGCGCAGGAGCTCGCCCGGCAC
GGCGCCCACGTGGTGCTGGCCGTGCGCGATCCGGACCGCGGGGTCGCCGCGGCGGCCCGC
ATCCAAAGCCGGGTGCCGTCGGCGCAACTGACGGTCAGACGGCTGGATCTTTCCCGTCTC
GCGTCGGTGCGTGCCGGCGCCGAGGAACTGCGCGACCGCTTCCCGCGCATCCACCTGCTG
GTCAACAACGCGGGCGTGATGTGGACCGACCGGGCCCGCACCCCGGACGGTCACGAACTC
CAGTTCGCCACGAACCACCTGGGGCACTTCGCCCTCACCGGCCTGCTCCTGGACAGCCTG
CGGGCCGCGCCGGGCGCGCGGGTCGTGACGATCAGCAGCTATCTGCACCGGCTGGGGCGC
ATCGACTTCAGCGACCTTCACGGCGAACGCCGCTACAGCCGGTACCGGGCCTACAACCAG
TCCAAGCTGGCCAACCTCATGTTCGCGCTGGAACTCCATCACAGACTGGCGGAGTCCGGC
GCGGAACTGGCCTCGCTCGCCGCTCATCCCGGGCTGACCGCGACCGGTCTGGGCCGGGAC
TTTCCCGCGCCCGTGCGCAGGCTCGGCTCCCCGCTCGCCCCGTTGTTCCTGCAGCCCGCC
GCGGCGGGGATGCTGCCTGGTCTGCGGGCGGCCACCGATCCCGGCGCGCGCGGGGGCGAG
TTCTACGGGCCCCTCGGCGTGACCGAGACCCGGGGCGCACCCGGGCTCGTGCGCCCCGGC
GGAGCAGCCGTCGACCCCAGGGCCCGGCGCCGCCTCTGGGAGGAGTCCGAGCACCTCACC
GGCGTACGCCTCCGGCCGTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR002198 Short-chain dehydrogenase/reductase SDR (Family)
[19-160] 6.3e-21 PF00106
PF00106   adh_short
IPR002347 Glucose/ribitol dehydrogenase (Family)
[19-36] 5.69999708783953e-10 PR00081 [95-106] 5.69999708783953e-10 PR00081 [140-156] 5.69999708783953e-10 PR00081 [178-197] 5.69999708783953e-10 PR00081
PR00081   GDHRDH
IPR016040 NAD(P)-binding domain (Domain)
[16-239] 1e-59 G3DSA:3.40.50.720
G3DSA:3.40.50.720   NAD(P)-bd
SignalP No significant hit
TMHMM No significant hit
C1027_00390 C1027_00390   C1027_00405 C1027_00405
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