first first   Teicp_00020 Teicp_00020

Teicp_00010 : CDS information

close this sectionLocation

Organism
StrainDSM 43866 (=NBRC 13999)
Entry nameTeicoplanin
Contig
Start / Stop / Direction1,517 / 552 / - [in whole cluster]
1,517 / 552 / - [in contig]
Locationcomplement(552..1517) [in whole cluster]
complement(552..1517) [in contig]
TypeCDS
Length966 bp (321 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category4.1 transcriptional regulator
Productputative AraC family transcriptional regulator
Product (GenBank)transcriptional regulator
Gene
Gene (GenBank)
EC number
Keyword
Note
Note (GenBank)
  • ORF11
Reference
ACC
PmId
[15113000] Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase. (Chem Biol. , 2004)
comment
DSM 43866株teicoplanin生合成gene clusterの同定論文。

tei orf11: Transcriptional regulator

orfs 10 and 11は知られたregulatorsに高い類似性を示す。これらはclusterの端にあり、他のグリコペプチド生合成clustersにhomologsがない。
Related Reference
ACC
Q6ZZK7
NITE
Teicp2_00070
comment
DSM 43866株でのtei orf11とAA配列完全一致。
UniProt 同一entry。

---
ATCC 31121株teicoplanin生合成gene cluster報告論文[PMID: 14702401]には、このORFについての記載なし。
ACC
Q9S166
PmId
comment
BLAST id43%
Streptomyces griseus_adpA
AdpA

A-factor-responsive transcriptional activator (AdpA)の特徴づけ。

実験報告は他にもたくさんある。
ACC
B6V2A5
PmId
comment
BLAST id43%
Streptomyces lividans
AdpA

AdpAによって調節される遺伝子の同定。
Family/Domain
FD
IPR018060
comment
[IPR018060] DNA binding HTH domain, AraC-type (Domain)
function; transcription factor activity, sequence-specific DNA binding

close this sectionSequence

selected fasta
>putative AraC family transcriptional regulator [transcriptional regulator]
MVPRRVALIVDEHSNPFEVGCACEIFGGRRRPQIGYELYELTVVSPTRSVPMRDRLFRVS
APGRLSDLDRADMIIVPNRPDVDVPSRGAVLAAIRRAHARGARLVGLCTGAFTLAEAGVL
DGRRAAVHWQLAPDFHRRFPAVRLEPDVLFVDDGDILTSAGSAAALDLGLHIVRRDHGTE
VANRVGRQLVFAAFRDGGQRQFVERPLPAPATSPLAPVLQWAQERLHLRLSVDDLARHGR
MSTATLHRRFRNEVGSTPLAWLTAQRVALACRLIEQGAAGVDAVARQSGLGTAANLRALL
RKHVGLSPSEYRRRFAADGAR
selected fasta
>putative AraC family transcriptional regulator [transcriptional regulator]
ATGGTGCCGCGGCGGGTCGCGCTGATAGTCGACGAACATTCCAACCCGTTCGAGGTGGGC
TGTGCCTGCGAGATCTTCGGCGGCCGCCGGCGCCCACAGATCGGCTACGAGCTGTACGAA
CTCACCGTCGTCAGCCCGACCAGATCGGTACCGATGCGGGACCGGCTGTTCCGCGTCAGC
GCGCCCGGGCGGCTGAGCGACCTGGACCGGGCCGACATGATCATCGTGCCGAACCGGCCG
GATGTCGACGTCCCGTCCCGCGGCGCGGTCCTGGCGGCGATCCGGCGGGCCCACGCGCGG
GGCGCCCGCCTGGTCGGCCTCTGCACCGGCGCCTTCACGCTCGCCGAGGCGGGGGTGCTC
GACGGCCGCCGCGCGGCGGTGCACTGGCAGCTGGCTCCGGACTTCCACCGGCGCTTCCCG
GCCGTACGGCTGGAGCCGGACGTGCTGTTCGTCGATGACGGCGACATCCTGACCTCGGCG
GGCAGCGCGGCGGCGCTCGACCTCGGCCTGCACATCGTCCGCCGCGACCACGGCACCGAG
GTGGCCAACCGGGTCGGCCGGCAGCTGGTGTTCGCCGCGTTCCGCGACGGCGGCCAGCGG
CAGTTCGTCGAACGCCCGCTGCCGGCGCCGGCGACGAGCCCGCTCGCGCCGGTCCTGCAG
TGGGCGCAGGAGCGCCTGCACCTGCGGCTGTCGGTCGACGACCTGGCCCGGCACGGCCGG
ATGAGCACCGCCACGCTGCACCGGCGCTTCCGCAACGAGGTGGGCAGCACCCCGCTGGCG
TGGCTGACCGCGCAGCGCGTCGCGCTGGCGTGCCGCCTGATCGAGCAGGGCGCCGCGGGC
GTGGACGCCGTGGCCCGGCAGTCCGGTCTGGGCACCGCCGCCAACCTGCGCGCCCTGCTG
CGTAAGCACGTGGGCCTGAGCCCGTCGGAGTACCGCCGGCGCTTCGCCGCCGACGGCGCG
CGGTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR009057 Homeodomain-like (Domain)
[211-262] 4.99999811956429e-08 SSF46689 [265-315] 4.99999811956429e-08 SSF46689
SSF46689   Homeodomain_like
[219-265] 2.7e-17 G3DSA:1.10.10.60 [266-315] 1.2e-09 G3DSA:1.10.10.60
G3DSA:1.10.10.60   Homeodomain-rel
IPR018060 DNA binding HTH domain, AraC-type (Domain)
[216-314] PS01124
PS01124   HTH_ARAC_FAMILY_2
[229-312] 1.39999892049878e-22 SM00342
SM00342   HTH_ARAC
IPR025628 DJ-1 domain, InhA-type (Domain)
[37-174] 2.3e-31 PF13278
PF13278   DUF4066
SignalP No significant hit
TMHMM No significant hit
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