BLAST table : Myxa_00040

DB	UniProtKB

	accession	alignment	Evalue	Score	Ident.	link	product	gene	organism	ec
1	Q93TX1_STIAU (Q93TX1)		0.0	2417	100%	UniProt GenBank	MxaB1	mxaB1	Stigmatella aurantiaca
2	Q1D3S9_MYXXD (Q1D3S9)		0.0	1807	76%	UniProt GenBank	Polyketide synthase type I	MXAN_4526	Myxococcus xanthus (strain DK 1622)
3	D3G7A5_SORCE (D3G7A5)	(6 hsp)	0.0	831	44%	UniProt GenBank	Polyketide synthase	epoC	Sorangium cellulosum Polyangium cellulosum
4	Q9KIZ7_SORCE (Q9KIZ7)	(6 hsp)	0.0	815	45%	UniProt GenBank	EpoD	epoD	Sorangium cellulosum Polyangium cellulosum
5	D2X8Z6_SORCE (D2X8Z6)	(6 hsp)	0.0	815	45%	UniProt GenBank	EpoD	epoD	Sorangium cellulosum Polyangium cellulosum
6	Q9L8C7_SORCE (Q9L8C7)	(6 hsp)	0.0	813	44%	UniProt GenBank	Polyketide synthase	epoC	Sorangium cellulosum Polyangium cellulosum
7	Q9KIZ5_SORCE (Q9KIZ5)		0.0	723	42%	UniProt GenBank	EpoF	epoF	Sorangium cellulosum Polyangium cellulosum
8	Q9L8C5_SORCE (Q9L8C5)		0.0	722	42%	UniProt GenBank	Polyketide synthase	epoE	Sorangium cellulosum Polyangium cellulosum
9	D2X8Z8_SORCE (D2X8Z8)		0.0	717	41%	UniProt GenBank	EpoF	epoF	Sorangium cellulosum Polyangium cellulosum
10	Q0VZ72_CHOCO (Q0VZ72)		0.0	715	40%	UniProt GenBank	Polyketide synthase	cmdB	Chondromyces crocatus
11	D3G7A7_SORCE (D3G7A7)		0.0	713	40%	UniProt GenBank	Polyketide synthase	epoE	Sorangium cellulosum Polyangium cellulosum
12	A9AV04_HERA2 (A9AV04)		0.0	699	38%	UniProt GenBank	Beta-ketoacyl synthase	Haur_3960	Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785)
13	B1GYF7_CHOCO (B1GYF7)		0.0	677	39%	UniProt GenBank	Polyketide synthase	ajuC	Chondromyces crocatus
14	B9ZUJ6_CHOCO (B9ZUJ6)		0.0	643	38%	UniProt GenBank	Polyketide synthase	cndA	Chondromyces crocatus
15	B1GYF9_CHOCO (B1GYF9)		0.0	640	38%	UniProt GenBank	Polyketide synthase	ajuE	Chondromyces crocatus
16	Q8RJY1_STIAU (Q8RJY1)		1e-178	631	37%	UniProt GenBank	StiF protein	stiF	Stigmatella aurantiaca
17	E0UL81_CYAP2 (E0UL81)		1e-176	625	34%	UniProt GenBank	Beta-ketoacyl synthase	Cyan7822_5857	Cyanothece sp. (strain PCC 7822)
18	B2J016_NOSP7 (B2J016)		1e-174	619	34%	UniProt GenBank	Beta-ketoacyl synthase	Npun_F3360	Nostoc punctiforme (strain ATCC 29133 / PCC 73102)	1.6.5.5 niceE keggE 2.3.1.94 niceE keggE
19	A9AV03_HERA2 (A9AV03)		1e-171	608	35%	UniProt GenBank	Beta-ketoacyl synthase	Haur_3959	Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785)
20	Q6DNE2_9CYAN (Q6DNE2)		1e-168	598	33%	UniProt GenBank	CurK	curK	Lyngbya majuscula
21	F4Y425_9CYAN (F4Y425)		1e-168	598	33%	UniProt GenBank	CurK Polyketide synthase module	LYNGBM3L_74450	Lyngbya majuscula 3L
22	E3FLA1_STIAD (E3FLA1)		1e-166	590	36%	UniProt GenBank	Polyketide synthase type I	spiD STAUR_5221	Stigmatella aurantiaca (strain DW4/3-1)
23	A8YP97_STIAU (A8YP97)		1e-166	590	36%	UniProt GenBank	Polyketide synthase AufI	aufI	Stigmatella aurantiaca
24	D0LS56_HALO1 (D0LS56)		1e-161	575	35%	UniProt GenBank	Acyl transferase	Hoch_1186	Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2)
25	C4NCC0_9CYAN (C4NCC0)		1e-158	563	33%	UniProt GenBank	Polyketide synthase	anaE OSCI_4070011	Oscillatoria sp. PCC 6506
26	Q6E7J8_9CYAN (Q6E7J8)		1e-156	559	32%	UniProt GenBank	JamL		Lyngbya majuscula
27	A6GKJ2_9DELT (A6GKJ2)		1e-155	555	36%	UniProt GenBank	Polyketide synthase type I	PPSIR1_15390	Plesiocystis pacifica SIR-1
28	B1GYF5_CHOCO (B1GYF5)		1e-147	528	35%	UniProt GenBank	Polyketide synthase	ajuA	Chondromyces crocatus
29	Q6DNE5_9CYAN (Q6DNE5)		1e-146	523	32%	UniProt GenBank	CurH	curH	Lyngbya majuscula
30	F4Y428_9CYAN (F4Y428)		1e-146	523	32%	UniProt GenBank	CurH Zn-dependent oxidoreductase/polyketide synthase module	LYNGBM3L_74480	Lyngbya majuscula 3L
31	B4WGS3_9SYNE (B4WGS3)		1e-145	520	31%	UniProt GenBank	KR domain family	S7335_4032	Synechococcus sp. PCC 7335
32	A7IE18_XANP2 (A7IE18)		1e-144	518	36%	UniProt GenBank	KR domain protein	Xaut_1010	Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2)
33	B4WGT1_9SYNE (B4WGT1)		1e-137	495	31%	UniProt GenBank	KR domain family	S7335_1374	Synechococcus sp. PCC 7335
34	B1WWV8_CYAA5 (B1WWV8)	(2 hsp)	1e-135	487	36%	UniProt GenBank	Probable polyketide synthase	cce_3079	Cyanothece sp. (strain ATCC 51142)
35	B0UE67_METS4 (B0UE67)		1e-134	485	36%	UniProt GenBank	Beta-ketoacyl synthase	M446_0172	Methylobacterium sp. (strain 4-46)
36	Q8YTN4_NOSS1 (Q8YTN4)	(2 hsp)	1e-130	472	34%	UniProt GenBank	Polyketide synthase	alr2680	Nostoc sp. (strain PCC 7120 / UTEX 2576)
37	E3FQI4_STIAD (E3FQI4)		1e-130	471	33%	UniProt GenBank	Tylactone synthase modules 4 & 5	STAUR_1685	Stigmatella aurantiaca (strain DW4/3-1)
38	E1VID6_9GAMM (E1VID6)	(2 hsp)	1e-129	469	31%	UniProt GenBank	Erythronolide synthase, modules 3 and 4	eryA HDN1F_09950	gamma proteobacterium HdN1	2.3.1.94 niceE keggE
39	A0Z9Q1_NODSP (A0Z9Q1)	(2 hsp)	1e-128	464	33%	UniProt GenBank	Polyketide synthase	N9414_20860	Nodularia spumigena CCY9414
40	B1WWV7_CYAA5 (B1WWV7)	(2 hsp)	1e-126	458	34%	UniProt GenBank	Polyketide synthase	cce_3078	Cyanothece sp. (strain ATCC 51142)
41	D5QVV8_METTR (D5QVV8)		1e-125	454	35%	UniProt GenBank	Acyl transferase	MettrDRAFT_3934	Methylosinus trichosporium OB3b
42	B4WHZ1_9SYNE (B4WHZ1)		1e-125	454	29%	UniProt GenBank	KR domain family	S7335_3862	Synechococcus sp. PCC 7335
43	Q6E7K0_9CYAN (Q6E7K0)	(3 hsp)	1e-123	448	34%	UniProt GenBank	JamJ		Lyngbya majuscula
44	Q4C7P2_CROWT (Q4C7P2)		1e-123	447	32%	UniProt GenBank	Zinc-containing alcohol dehydrogenase superfamily:Phosphopantetheine-binding	CwatDRAFT_5563	Crocosphaera watsonii WH 8501
45	A3ZMA9_9PLAN (A3ZMA9)		1e-120	439	31%	UniProt GenBank	Polyketide synthase	DSM3645_00150	Blastopirellula marina DSM 3645
46	F4XWJ9_9CYAN (F4XWJ9)	(2 hsp)	1e-119	435	34%	UniProt GenBank	NADPH:quinone reductase/Zn-dependent oxidoreductase	LYNGBM3L_44020	Lyngbya majuscula 3L
47	E0KN87_STRVO (E0KN87)		1e-117	429	33%	UniProt GenBank	Acyl transferase	StrviDRAFT_4114	Streptomyces violaceusniger Tu 4113
48	Q099Y5_STIAD (Q099Y5)		1e-117	427	31%	UniProt GenBank	Oxidoreductase, short chain dehydrogenase/reductase family	STIAU_7352	Stigmatella aurantiaca (strain DW4/3-1)
49	A0Z9Q2_NODSP (A0Z9Q2)	(2 hsp)	1e-117	427	34%	UniProt GenBank	Polyketide synthase	N9414_20865	Nodularia spumigena CCY9414
50	E3FLG1_STIAD (E3FLG1)		1e-117	427	31%	UniProt GenBank	Mycocerosic acid synthase	mas STAUR_5282	Stigmatella aurantiaca (strain DW4/3-1)	2.3.1.111 niceE keggE
51	F2ARE8_RHOBA (F2ARE8)		1e-115	421	28%	UniProt GenBank	Type I polyketide synthase	RBWH47_03706	Rhodopirellula baltica WH47
52	Q8YTN5_NOSS1 (Q8YTN5)	(2 hsp)	1e-115	421	33%	UniProt GenBank	Polyketide synthase	alr2679	Nostoc sp. (strain PCC 7120 / UTEX 2576)
53	Q0RLH1_FRAAA (Q0RLH1)		1e-114	420	31%	UniProt GenBank	Putative polyketide synthase	FRAAL2989	Frankia alni (strain ACN14a)
54	C5AND0_BURGB (C5AND0)		1e-114	417	33%	UniProt GenBank	Beta-ketoacyl synthase	bglu_2p0610	Burkholderia glumae (strain BGR1)
55	Q10Y11_TRIEI (Q10Y11)	(2 hsp)	1e-113	416	34%	UniProt GenBank	Beta-ketoacyl synthase	Tery_3819	Trichodesmium erythraeum (strain IMS101)
56	Q7UJD0_RHOBA (Q7UJD0)		1e-113	414	28%	UniProt GenBank	Polyketide synthase	RB11975	Rhodopirellula baltica
57	B6WQE5_9DELT (B6WQE5)		1e-112	412	31%	UniProt GenBank	Putative uncharacterized protein	DESPIG_00265	Desulfovibrio piger ATCC 29098
58	Q49933_MYCLE (Q49933)		1e-112	411	31%	UniProt GenBank	PksD Polyketide synthase	ML2355	Mycobacterium leprae
59	B8ZT38_MYCLB (B8ZT38)		1e-112	411	31%	UniProt GenBank	Polyketide synthase	MLBr02355	Mycobacterium leprae (strain Br4923)
60	D3D724_9ACTO (D3D724)		1e-112	410	34%	UniProt GenBank	Acyl transferase	FrEUN1fDRAFT_5596	Frankia sp. EUN1f
61	A0PQ37_MYCUA (A0PQ37)		1e-110	407	30%	UniProt GenBank	Phenolpthiocerol synthesis type-I polyketide synthase PpsC	ppsC MUL_2017	Mycobacterium ulcerans (strain Agy99)
62	A4FCW1_SACEN (A4FCW1)		1e-110	405	32%	UniProt GenBank	Polyketide synthase type I	SACE_2595	Saccharopolyspora erythraea (strain NRRL 23338)
63	B2HIM9_MYCMM (B2HIM9)		1e-110	405	30%	UniProt GenBank	Phenolpthiocerol synthesis type-I polyketide synthase PpsC	ppsC MMAR_1774	Mycobacterium marinum (strain ATCC BAA-535 / M)
64	Q9L1V8_STRCO (Q9L1V8)		1e-110	404	31%	UniProt GenBank	Polyketide synthase	SCO6827	Streptomyces coelicolor
65	A8LGZ0_FRASN (A8LGZ0)		1e-110	403	30%	UniProt GenBank	Acyl transferase	Franean1_3359	Frankia sp. (strain EAN1pec)
66	B3PDZ5_CELJU (B3PDZ5)		1e-109	402	30%	UniProt GenBank	MxaD	mxaD CJA_3198	Cellvibrio japonicus (strain Ueda107) Pseudomonas fluorescens subsp. cellulosa
67	Q4C7P4_CROWT (Q4C7P4)	(2 hsp)	1e-109	402	31%	UniProt GenBank	Beta-ketoacyl synthase:Acyl transferase region:Zinc-containing alcohol dehydrogenase superfamily:Phosphopantetheine-binding	CwatDRAFT_5561	Crocosphaera watsonii WH 8501
68	E3FJX7_STIAD (E3FJX7)		1e-109	401	35%	UniProt GenBank	Polyketide synthase AufE	aufE STAUR_5217	Stigmatella aurantiaca (strain DW4/3-1)
69	A8YP93_STIAU (A8YP93)		1e-109	401	35%	UniProt GenBank	Polyketide synthase AufE	aufE	Stigmatella aurantiaca
70	Q090D9_STIAD (Q090D9)		1e-109	400	34%	UniProt GenBank	EpoD	STIAU_7285	Stigmatella aurantiaca (strain DW4/3-1)
71	E2V131_MYCTU (E2V131)		1e-109	400	31%	UniProt GenBank	Putative phosphopantetheine attachment site	TMGG_02470	Mycobacterium tuberculosis SUMu007
72	E1HD26_MYCTU (E1HD26)		1e-109	400	31%	UniProt GenBank	Putative phosphopantetheine attachment site	TMAG_01136	Mycobacterium tuberculosis SUMu001
73	D5Y725_MYCTU (D5Y725)		1e-109	400	30%	UniProt GenBank	Phenolpthiocerol synthesis type-I polyketide synthase ppsc	TBEG_01717	Mycobacterium tuberculosis T85
74	C1AG49_MYCBT (C1AG49)		1e-109	400	31%	UniProt GenBank	Phenolpthiocerol synthesis type-I polyketide synthase	ppsC JTY_2950	Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019)
75	A5WRI5_MYCTF (A5WRI5)		1e-109	400	31%	UniProt GenBank	Phenolpthiocerol synthesis type-I polyketide synthase ppsC	TBFG_12947	Mycobacterium tuberculosis (strain F11)
76	A5U6U0_MYCTA (A5U6U0)		1e-109	400	31%	UniProt GenBank	Phenolpthiocerol synthesis type-I polyketide synthase PpsC	ppsC MRA_2959	Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
77	A1KMS8_MYCBP (A1KMS8)		1e-109	400	31%	UniProt GenBank	Phenolpthiocerol synthesis type-I polyketide synthase ppsC	ppsC BCG_2955	Mycobacterium bovis (strain BCG / Pasteur 1173P2)
78	F8M4T2_9MYCO (F8M4T2)		1e-109	400	31%	UniProt GenBank	Phenolpthiocerol synthesis type-I polyketide synthase PPSC	ppsC MAF_29380	Mycobacterium africanum GM041182
79	F7WYM3_MYCTU (F7WYM3)		1e-109	400	31%	UniProt GenBank	Polyketide synthase	CCDC5180_2657	Mycobacterium tuberculosis CCDC5180
80	F7WIY7_MYCTU (F7WIY7)		1e-109	400	31%	UniProt GenBank	Polyketide synthase	CCDC5079_2693	Mycobacterium tuberculosis CCDC5079
81	F2V8X9_MYCTU (F2V8X9)		1e-109	400	31%	UniProt GenBank	Phenolpthiocerol synthesis type-I polyketide synthase ppsC	TBPG_02455	Mycobacterium tuberculosis W-148
82	E2W936_MYCTU (E2W936)		1e-109	400	31%	UniProt GenBank	Phenolpthiocerol synthesis type-I polyketide synthase ppsc	TMKG_03368	Mycobacterium tuberculosis SUMu011
83	E2VCA3_MYCTU (E2VCA3)		1e-109	400	31%	UniProt GenBank	Phenolpthiocerol synthesis type-I polyketide synthase ppsc	TMHG_02141	Mycobacterium tuberculosis SUMu008
84	E2UDP3_MYCTU (E2UDP3)		1e-109	400	31%	UniProt GenBank	Phenolpthiocerol synthesis type-I polyketide synthase ppsc	TMEG_02202	Mycobacterium tuberculosis SUMu005
85	E2U124_MYCTU (E2U124)		1e-109	400	31%	UniProt GenBank	Phenolpthiocerol synthesis type-I polyketide synthase ppsc	TMDG_00130	Mycobacterium tuberculosis SUMu004
86	E2TQD9_MYCTU (E2TQD9)		1e-109	400	31%	UniProt GenBank	Phenolpthiocerol synthesis type-I polyketide synthase ppsc	TMCG_02185	Mycobacterium tuberculosis SUMu003
87	E2TD93_MYCTU (E2TD93)		1e-109	400	31%	UniProt GenBank	Phenolpthiocerol synthesis type-I polyketide synthase ppsc	TMBG_03082	Mycobacterium tuberculosis SUMu002
88	D7EVS5_MYCTU (D7EVS5)		1e-109	400	31%	UniProt GenBank	Phenolpthiocerol synthesis type-I polyketide synthase ppsc	TBAG_01821	Mycobacterium tuberculosis 94_M4241A
89	D6FPC5_MYCTU (D6FPC5)		1e-109	400	31%	UniProt GenBank	Phenolpthiocerol synthesis type-I polyketide synthase ppsC	TBOG_03483	Mycobacterium tuberculosis K85
90	D6FKG8_MYCTU (D6FKG8)		1e-109	400	31%	UniProt GenBank	Phenolpthiocerol synthesis type-I polyketide synthase ppsC	TBNG_03594	Mycobacterium tuberculosis CPHL_A
91	D5ZKC4_MYCTU (D5ZKC4)		1e-109	400	31%	UniProt GenBank	Phenolpthiocerol synthesis type-I polyketide synthase ppsC	TBJG_02541	Mycobacterium tuberculosis T17
92	D5YVL7_MYCTU (D5YVL7)		1e-109	400	31%	UniProt GenBank	Phenolpthiocerol synthesis type-I polyketide synthase ppsc	TBBG_03140	Mycobacterium tuberculosis 02_1987
93	D5YIP3_MYCTU (D5YIP3)		1e-109	400	31%	UniProt GenBank	Phenolpthiocerol synthesis type-I polyketide synthase ppsc	TBGG_02136	Mycobacterium tuberculosis EAS054
94	PPSC_MYCTU (P96202)		1e-109	400	31%	UniProt GenBank	Phthiocerol synthesis polyketide synthase type I PpsC Beta-ketoacyl-acyl-carrier-protein synthase I Beta-ketoacyl-acyl-carrier-protein synthase I	ppsC Rv2933	Mycobacterium tuberculosis	2.3.1.41 niceE keggE
95	PPSC_MYCBO (Q7TXL8)		1e-109	400	31%	UniProt GenBank	Phthiocerol/phenolphthiocerol synthesis polyketide synthase type I PpsC Beta-ketoacyl-acyl-carrier-protein synthase I Beta-ketoacyl-acyl-carrier-protein synthase I	ppsC Mb2958	Mycobacterium bovis	2.3.1.41 niceE keggE
96	Q7D6F1_MYCTU (Q7D6F1)		1e-108	400	31%	UniProt GenBank	Polyketide synthase	MT3003	Mycobacterium tuberculosis
97	E9ZN21_MYCTU (E9ZN21)		1e-108	400	31%	UniProt GenBank	Phenolpthiocerol synthesis type-I polyketide synthase ppsC	TMMG_03456	Mycobacterium tuberculosis CDC1551A
98	A2VLR0_MYCTU (A2VLR0)		1e-108	400	31%	UniProt GenBank	Phenolpthiocerol synthesis type-I polyketide synthase ppsC	TBCG_02871	Mycobacterium tuberculosis C
99	C6DWC1_MYCTK (C6DWC1)		1e-108	400	31%	UniProt GenBank	Phenolpthiocerol synthesis type-I polyketide synthase ppsC	TBMG_01039	Mycobacterium tuberculosis (strain KZN 1435 / MDR)
100	F2GP64_MYCTU (F2GP64)		1e-108	400	31%	UniProt GenBank	Phenolpthiocerol synthesis type-I polyketide synthase ppsc	TBSG_01047	Mycobacterium tuberculosis KZN 4207

accession

alignment

Evalue

Score

Ident.

link

information

pubmed

Q93TX1_STIAU
(Q93TX1)

0.0

2417

100%

Product: MxaB1
Gene: mxaB1
Organism: Stigmatella aurantiaca

1uniprot[Pubmed] 11182319 [Medline] 21110452
Novel features in a combined polyketide synthase/non-ribosomal peptide synthetase: the myxalamid biosynthetic gene cluster of the myxobacterium Stigmatella aurantiaca Sga15.(Chem. Biol.) [2001]

Q1D3S9_MYXXD
(Q1D3S9)

0.0

1807

76%

Product: Polyketide synthase type I
Gene: MXAN_4526
Organism: Myxococcus xanthus (strain DK 1622)

1uniprot[Pubmed] 17015832
Evolution of sensory complexity recorded in a myxobacterial genome.(Proc. Natl. Acad. Sci. U.S.A.) [2006]

Q9KIZ7_SORCE
(Q9KIZ7)

(6 hsp)

0.0

815

45%

Product: EpoD
Gene: epoD
Organism: Sorangium cellulosum
Polyangium cellulosum

[pubmed all]
1uniprot[Pubmed] 10649995 [Medline] 20115953 Cloning and heterologous expression of the epothilone gene cluster.(Science) [2000]
2uniprot[Pubmed] 10831849 [Medline] 20293058 Isolation and characterization of the epothilone biosynthetic gene cluster from Sorangium cellulosum.(Gene) [2000]

Q9L8C7_SORCE
(Q9L8C7)

(6 hsp)

0.0

813

44%

Product: Polyketide synthase
Gene: epoC
Organism: Sorangium cellulosum
Polyangium cellulosum

1uniprot[Pubmed] 10662695 [Medline] 20130945
The biosynthetic gene cluster for the microtubule-stabilizing agents epothilones A and B from Sorangium cellulosum So ce90.(Chem. Biol.) [2000]

Q9KIZ5_SORCE
(Q9KIZ5)

0.0

723

42%

Product: EpoF
Gene: epoF
Organism: Sorangium cellulosum
Polyangium cellulosum

[pubmed all]
1uniprot[Pubmed] 10649995 [Medline] 20115953 Cloning and heterologous expression of the epothilone gene cluster.(Science) [2000]
2uniprot[Pubmed] 10831849 [Medline] 20293058 Isolation and characterization of the epothilone biosynthetic gene cluster from Sorangium cellulosum.(Gene) [2000]

Q9L8C5_SORCE
(Q9L8C5)

0.0

722

42%

Product: Polyketide synthase
Gene: epoE
Organism: Sorangium cellulosum
Polyangium cellulosum

1uniprot[Pubmed] 10662695 [Medline] 20130945
The biosynthetic gene cluster for the microtubule-stabilizing agents epothilones A and B from Sorangium cellulosum So ce90.(Chem. Biol.) [2000]

Q0VZ72_CHOCO
(Q0VZ72)

0.0

715

40%

Product: Polyketide synthase
Gene: cmdB
Organism: Chondromyces crocatus

1uniprot[Pubmed] 16793524
Molecular and biochemical studies of chondramide formation-highly cytotoxic natural products from Chondromyces crocatus Cm c5.(Chem. Biol.) [2006]

B9ZUJ6_CHOCO
(B9ZUJ6)

0.0

643

38%

Product: Polyketide synthase
Gene: cndA
Organism: Chondromyces crocatus

1uniprot
Novel chemistry in the biosynthesis of the antibiotic chondrochlorens.(Chem. Biol.) [2009]

Q8RJY1_STIAU
(Q8RJY1)

1e-178

631

37%

Product: StiF protein
Gene: stiF
Organism: Stigmatella aurantiaca

1uniprot[Pubmed] 11809757 [Medline] 21935336
The biosynthesis of the aromatic myxobacterial electron transport inhibitor stigmatellin is directed by a novel type of modular polyketide synthase.(J. Biol. Chem.) [2002]

Q6DNE2_9CYAN
(Q6DNE2)

1e-168

598

33%

Product: CurK
Gene: curK
Organism: Lyngbya majuscula

[pubmed all]
1uniprot[Pubmed] 15332855 Biosynthetic pathway and gene cluster analysis of curacin A, an antitubulin natural product from the tropical marine cyanobacterium Lyngbya majuscula.(J. Nat. Prod.) [2004]
2uniprot[Pubmed] 20152156 Crystal structures of dehydratase domains from the curacin polyketide biosynthetic pathway.(Structure) [2010]

F4Y425_9CYAN
(F4Y425)

1e-168

598

33%

Product: CurK
Polyketide synthase module
Gene: LYNGBM3L_74450
Organism: Lyngbya majuscula 3L

1uniprot
Genomic insights into the physiology and ecology of the marine filamentous cyanobacterium Lyngbya majuscula.(Proc. Natl. Acad. Sci. U.S.A.) [2011]

2uniprot[Pubmed] 21555588
Genomic insights into the physiology and ecology of the marine filamentous cyanobacterium Lyngbya majuscula.(Proc. Natl. Acad. Sci. U.S.A.) [2011]

A8YP97_STIAU
(A8YP97)

1e-166

590

36%

Product: Polyketide synthase AufI
Gene: aufI
Organism: Stigmatella aurantiaca

1uniprot[Pubmed] 17919655
From Genetic Diversity to Metabolic Unity: Studies on the Biosynthesis of Aurafurones and Aurafuron-like Structures in Myxobacteria and Streptomycetes.(J. Mol. Biol.) [2007]

C4NCC0_9CYAN
(C4NCC0)

1e-158

563

33%

Product: Polyketide synthase
Gene: anaE
OSCI_4070011
Organism: Oscillatoria sp. PCC 6506

1uniprot[Pubmed] 19489636
Evidence that biosynthesis of the neurotoxic alkaloids anatoxin-a and homoanatoxin-a in the cyanobacterium Oscillatoria PCC 6506 occurs on a modular polyketide synthase initiated by L-proline.(J. Am. Chem. Soc.) [2009]

2uniprot
The Genome Sequence of the Cyanobacterium Oscillatoria sp. PCC 6506 Reveals Several Gene Clusters Responsible for the Biosynthesis of Toxins and Secondary Metabolites.(J. Bacteriol.) [2010]

Q6E7J8_9CYAN
(Q6E7J8)

1e-156

559

32%

Product: JamL
Gene
Organism: Lyngbya majuscula

1uniprot[Pubmed] 15217615
Structure and biosynthesis of the jamaicamides, new mixed polyketide-peptide neurotoxins from the marine cyanobacterium Lyngbya majuscula.(Chem. Biol.) [2004]

Q6DNE5_9CYAN
(Q6DNE5)

1e-146

523

32%

Product: CurH
Gene: curH
Organism: Lyngbya majuscula

[pubmed all]
1uniprot[Pubmed] 15332855 Biosynthetic pathway and gene cluster analysis of curacin A, an antitubulin natural product from the tropical marine cyanobacterium Lyngbya majuscula.(J. Nat. Prod.) [2004]
2uniprot[Pubmed] 20152156 Crystal structures of dehydratase domains from the curacin polyketide biosynthetic pathway.(Structure) [2010]

F4Y428_9CYAN
(F4Y428)

1e-146

523

32%

Product: CurH
Zn-dependent oxidoreductase/polyketide synthase module
Gene: LYNGBM3L_74480
Organism: Lyngbya majuscula 3L

1uniprot
Genomic insights into the physiology and ecology of the marine filamentous cyanobacterium Lyngbya majuscula.(Proc. Natl. Acad. Sci. U.S.A.) [2011]

2uniprot[Pubmed] 21555588
Genomic insights into the physiology and ecology of the marine filamentous cyanobacterium Lyngbya majuscula.(Proc. Natl. Acad. Sci. U.S.A.) [2011]

B1WWV8_CYAA5
(B1WWV8)

(2 hsp)

1e-135

487

36%

Product: Probable polyketide synthase
Gene: cce_3079
Organism: Cyanothece sp. (strain ATCC 51142)

1uniprot[Pubmed] 18812508
The genome of Cyanothece 51142, a unicellular diazotrophic cyanobacterium important in the marine nitrogen cycle.(Proc. Natl. Acad. Sci. U.S.A.) [2008]

Q8YTN4_NOSS1
(Q8YTN4)

(2 hsp)

1e-130

472

34%

Product: Polyketide synthase
Gene: alr2680
Organism: Nostoc sp. (strain PCC 7120 / UTEX 2576)

1uniprot[Pubmed] 11759840 [Medline] 21595285
Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120.(DNA Res.) [2001]

E1VID6_9GAMM
(E1VID6)

(2 hsp)

1e-129

469

31%

Product: Erythronolide synthase, modules 3 and 4
Gene: eryA
HDN1F_09950
Organism: gamma proteobacterium HdN1

1uniprot
Alkane degradation by a new type of denitrifying bacterium with possible involvement of the electron acceptor in substrate activation.(Environ. Microbiol.) [2010]

B1WWV7_CYAA5
(B1WWV7)

(2 hsp)

1e-126

458

34%

Product: Polyketide synthase
Gene: cce_3078
Organism: Cyanothece sp. (strain ATCC 51142)

1uniprot[Pubmed] 18812508
The genome of Cyanothece 51142, a unicellular diazotrophic cyanobacterium important in the marine nitrogen cycle.(Proc. Natl. Acad. Sci. U.S.A.) [2008]

D5QVV8_METTR
(D5QVV8)

1e-125

454

35%

Product: Acyl transferase
Gene: MettrDRAFT_3934
Organism: Methylosinus trichosporium OB3b

1uniprot[Pubmed] 20952571
Genome Sequence of the Obligate Methanotroph Methylosinus trichosporium Strain OB3b.(J. Bacteriol.) [2010]

Q6E7K0_9CYAN
(Q6E7K0)

(3 hsp)

1e-123

448

34%

Product: JamJ
Gene
Organism: Lyngbya majuscula

1uniprot[Pubmed] 15217615
Structure and biosynthesis of the jamaicamides, new mixed polyketide-peptide neurotoxins from the marine cyanobacterium Lyngbya majuscula.(Chem. Biol.) [2004]

F4XWJ9_9CYAN
(F4XWJ9)

(2 hsp)

1e-119

435

34%

Product: NADPH:quinone reductase/Zn-dependent oxidoreductase
Gene: LYNGBM3L_44020
Organism: Lyngbya majuscula 3L

1uniprot
Genomic insights into the physiology and ecology of the marine filamentous cyanobacterium Lyngbya majuscula.(Proc. Natl. Acad. Sci. U.S.A.) [2011]

Q8YTN5_NOSS1
(Q8YTN5)

(2 hsp)

1e-115

421

33%

Product: Polyketide synthase
Gene: alr2679
Organism: Nostoc sp. (strain PCC 7120 / UTEX 2576)

1uniprot[Pubmed] 11759840 [Medline] 21595285
Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120.(DNA Res.) [2001]

Q0RLH1_FRAAA
(Q0RLH1)

1e-114

420

31%

Product: Putative polyketide synthase
Gene: FRAAL2989
Organism: Frankia alni (strain ACN14a)

1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]

C5AND0_BURGB
(C5AND0)

1e-114

417

33%

Product: Beta-ketoacyl synthase
Gene: bglu_2p0610
Organism: Burkholderia glumae (strain BGR1)

1uniprot[Pubmed] 19329631
Complete genome sequence of Burkholderia glumae BGR1.(J. Bacteriol.) [2009]

Q7UJD0_RHOBA
(Q7UJD0)

1e-113

414

28%

Product: Polyketide synthase
Gene: RB11975
Organism: Rhodopirellula baltica

1uniprot[Pubmed] 12835416 [Medline] 22735913
Complete genome sequence of the marine planctomycete Pirellula sp. strain 1.(Proc. Natl. Acad. Sci. U.S.A.) [2003]

Q49933_MYCLE
(Q49933)

1e-112

411

31%

Product: PksD
Polyketide synthase
Gene: ML2355
Organism: Mycobacterium leprae

1uniprot[Pubmed] 11234002 [Medline] 21128732
Massive gene decay in the leprosy bacillus.(Nature) [2001]

B8ZT38_MYCLB
(B8ZT38)

1e-112

411

31%

Product: Polyketide synthase
Gene: MLBr02355
Organism: Mycobacterium leprae (strain Br4923)

1uniprot[Pubmed] 19881526
Comparative genomic and phylogeographic analysis of Mycobacterium leprae.(Nat. Genet.) [2009]

A0PQ37_MYCUA
(A0PQ37)

1e-110

407

30%

Product: Phenolpthiocerol synthesis type-I polyketide synthase PpsC
Gene: ppsC
MUL_2017
Organism: Mycobacterium ulcerans (strain Agy99)

1uniprot[Pubmed] 17210928
Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer.(Genome Res.) [2007]

A4FCW1_SACEN
(A4FCW1)

1e-110

405

32%

Product: Polyketide synthase type I
Gene: SACE_2595
Organism: Saccharopolyspora erythraea (strain NRRL 23338)

1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]

B2HIM9_MYCMM
(B2HIM9)

1e-110

405

30%

Product: Phenolpthiocerol synthesis type-I polyketide synthase PpsC
Gene: ppsC
MMAR_1774
Organism: Mycobacterium marinum (strain ATCC BAA-535 / M)

1uniprot[Pubmed] 18403782
Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis.(Genome Res.) [2008]

Q9L1V8_STRCO
(Q9L1V8)

1e-110

404

31%

Product: Polyketide synthase
Gene: SCO6827
Organism: Streptomyces coelicolor

1uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]

A8LGZ0_FRASN
(A8LGZ0)

1e-110

403

30%

Product: Acyl transferase
Gene: Franean1_3359
Organism: Frankia sp. (strain EAN1pec)

1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]

B3PDZ5_CELJU
(B3PDZ5)

1e-109

402

30%

Product: MxaD
Gene: mxaD
CJA_3198
Organism: Cellvibrio japonicus (strain Ueda107)
Pseudomonas fluorescens subsp. cellulosa

1uniprot[Pubmed] 18556790
Insights into plant cell wall degradation from the genome sequence of the soil bacterium Cellvibrio japonicus.(J. Bacteriol.) [2008]

A8YP93_STIAU
(A8YP93)

1e-109

401

35%

Product: Polyketide synthase AufE
Gene: aufE
Organism: Stigmatella aurantiaca

1uniprot[Pubmed] 17919655
From Genetic Diversity to Metabolic Unity: Studies on the Biosynthesis of Aurafurones and Aurafuron-like Structures in Myxobacteria and Streptomycetes.(J. Mol. Biol.) [2007]

C1AG49_MYCBT
(C1AG49)

1e-109

400

31%

Product: Phenolpthiocerol synthesis type-I polyketide synthase
Gene: ppsC
JTY_2950
Organism: Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019)

1uniprot[Pubmed] 19200449
Whole genome sequence analysis of Mycobacterium bovis bacillus Calmette-Guerin (BCG) Tokyo 172: a comparative study of BCG vaccine substrains.(Vaccine) [2009]

A1KMS8_MYCBP
(A1KMS8)

1e-109

400

31%

Product: Phenolpthiocerol synthesis type-I polyketide synthase ppsC
Gene: ppsC
BCG_2955
Organism: Mycobacterium bovis (strain BCG / Pasteur 1173P2)

1uniprot[Pubmed] 17372194
Genome plasticity of BCG and impact on vaccine efficacy.(Proc. Natl. Acad. Sci. U.S.A.) [2007]

PPSC_MYCTU
(P96202)

1e-109

400

31%

Product: Phthiocerol synthesis polyketide synthase type I PpsC
Beta-ketoacyl-acyl-carrier-protein synthase I
Beta-ketoacyl-acyl-carrier-protein synthase I
Gene: ppsC
Rv2933
Organism: Mycobacterium tuberculosis

[pubmed all]
1uniprot[Pubmed] 9634230 [Medline] 98295987 Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.(Nature) [1998]
2uniprot[Pubmed] 19099550 targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis.(BMC Syst. Biol.) [2008]

PPSC_MYCBO
(Q7TXL8)

1e-109

400

31%

Product: Phthiocerol/phenolphthiocerol synthesis polyketide synthase type I PpsC
Beta-ketoacyl-acyl-carrier-protein synthase I
Beta-ketoacyl-acyl-carrier-protein synthase I
Gene: ppsC
Mb2958
Organism: Mycobacterium bovis

[pubmed all]
1uniprot[Pubmed] 12788972 [Medline] 22709107 The complete genome sequence of Mycobacterium bovis.(Proc. Natl. Acad. Sci. U.S.A.) [2003]
2uniprot[Pubmed] 9201977 Gene knockout reveals a novel gene cluster for the synthesis of a class of cell wall lipids unique to pathogenic mycobacteria.(J. Biol. Chem.) [1997]

Q7D6F1_MYCTU
(Q7D6F1)

1e-108

400

31%

Product: Polyketide synthase
Gene: MT3003
Organism: Mycobacterium tuberculosis

1uniprot[Pubmed] 12218036 [Medline] 22206494
Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains.(J. Bacteriol.) [2002]