| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
Q6V1N2_9ACTO (Q6V1N2) |
|
|
0.0 |
818 |
100% |
|
- Product
- PlmT4
- Gene
- plmT4
- Organism
- Streptomyces sp. HK803
|
1uniprot[Pubmed] 12819191 [Medline] 22841069 Enhancement and selective production of phoslactomycin B, a protein phosphatase IIa inhibitor, through identification and engineering of the corresponding biosynthetic gene cluster.(J. Biol. Chem.) [2003] |
|
3
|
D2B704_STRRD (D2B704) |
|
|
1e-96 |
357 |
45% |
|
- Product
- Putative cytochrome P450
- Gene
- Sros_4934
- Organism
- Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
|
1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010] |
|
4
|
C7MXK5_SACVD (C7MXK5) |
|
|
5e-94 |
349 |
45% |
|
- Product
- Cytochrome P450
- Gene
- Svir_22760
- Organism
- Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
|
1uniprot Complete genome sequence of Saccharomonospora viridis type strain (P101T).(Stand. Genomic Sci.) [2009] |
|
5
|
D2B913_STRRD (D2B913) |
|
|
4e-93 |
346 |
45% |
|
- Product
- Putative cytochrome P450
- Gene
- Sros_7070
- Organism
- Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
|
1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010] |
|
8
|
D8I768_AMYMU (D8I768) |
|
|
7e-89 |
332 |
44% |
|
- Product
- Cytochrome P450
- Gene
- AMED_3473
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
16
|
A4FDJ6_SACEN (A4FDJ6) |
|
|
4e-85 |
320 |
41% |
|
- Product
- Cytochrome P450 hydroxylase
- Gene
- cyp7
SACE_2842
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
19
|
D8I6M4_AMYMU (D8I6M4) |
|
|
7e-85 |
318 |
42% |
|
- Product
- Cytochrome P450
- Gene
- AMED_7228
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
22
|
C6WQG7_ACTMD (C6WQG7) |
|
|
2e-84 |
317 |
41% |
|
- Product
- Cytochrome P450
- Gene
- Amir_2894
- Organism
- Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
|
1uniprot Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009] |
|
30
|
Q82MP9_STRAW (Q82MP9) |
|
|
3e-83 |
313 |
44% |
|
- Product
- Putative cytochrome P450
- Gene
- cyp7
SAV1611 SAV_1611
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
33
|
CPS2_STRCC (Q59831) |
|
|
4e-83 |
313 |
43% |
|
- Product
- Cytochrome P450 105A3
Cytochrome P450 sca-2 Cytochrome P450 sca-2
- Gene
- CYP105A3
- Organism
- Streptomyces carbophilus
|
1uniprot[Pubmed] 7557483 [Medline] 96001248 Cloning, characterization and expression of the gene encoding cytochrome P-450sca-2 from Streptomyces carbophilus involved in production of pravastatin, a specific HMG-CoA reductase inhibitor.(Gene) [1995] | 2uniprot[Pubmed] 2509201 [Medline] 90032660 Purification and characterization of cytochrome P-450sca from Streptomyces carbophilus. ML-236B (compactin) induces a cytochrome P-450sca in Streptomyces carbophilus that hydroxylates ML-236B to pravastatin sodium (CS-514), a tissue-selective inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme-A reductase.(Eur. J. Biochem.) [1989] | 3uniprot[Pubmed] 10329788 [Medline] 99263338 Crystallization and preliminary X-ray diffraction analysis of cytochrome P450sca-2 from Streptomyces carbophilus involved in production of pravastatin sodium, a tissue-selective inhibitor of HMG-CoA reductase.(Acta Crystallogr. D) [1999] | [pubmed all]
|
34
|
CPXE_STRGO (P18326) |
|
|
6e-83 |
312 |
42% |
|
- Product
- Cytochrome P450-SU1
CYP105A1 Cytochrome P450-CVA1
- Gene
- CYP105A1
suaC
- Organism
- Streptomyces griseolus
|
1uniprot[Pubmed] 2345149 [Medline] 90264332 Genes for two herbicide-inducible cytochromes P-450 from Streptomyces griseolus.(J. Bacteriol.) [1990] |
|
37
|
A8KXU3_FRASN (A8KXU3) |
|
|
2e-82 |
311 |
43% |
|
- Product
- Cytochrome P450
- Gene
- Franean1_3475
- Organism
- Frankia sp. (strain EAN1pec)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
39
|
D8I294_AMYMU (D8I294) |
|
|
4e-82 |
310 |
41% |
|
- Product
- Cytochrome P450
- Gene
- AMED_0876
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
42
|
Q5ENH9_PSEAH (Q5ENH9) |
|
|
8e-82 |
308 |
40% |
|
- Product
- FadC
- Gene
- fadC
- Organism
- Pseudonocardia autotrophica
Amycolata autotrophica Nocardia autotrophica
|
1uniprot[Pubmed] 15752735 A gene cluster for the fatty acid catabolism from Pseudonocardia autotrophica BCRC12444.(Biochem. Biophys. Res. Commun.) [2005] |
|
43
|
D3PYH2_STANL (D3PYH2) |
|
|
8e-82 |
308 |
43% |
|
- Product
- Cytochrome P450
- Gene
- Snas_1843
- Organism
- Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)
|
1uniprot Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21T).(Stand. Genomic Sci.) [2009] |
|
45
|
Q742Y1_MYCPA (Q742Y1) |
|
|
9e-82 |
308 |
40% |
|
- Product
- Putative uncharacterized protein
- Gene
- MAP_0704
- Organism
- Mycobacterium paratuberculosis
|
1uniprot[Pubmed] 16116077 The complete genome sequence of Mycobacterium avium subspecies paratuberculosis.(Proc. Natl. Acad. Sci. U.S.A.) [2005] |
|
46
|
Q73ZY2_MYCPA (Q73ZY2) |
|
|
1e-81 |
308 |
40% |
|
- Product
- Putative uncharacterized protein
- Gene
- MAP_1469c
- Organism
- Mycobacterium paratuberculosis
|
1uniprot[Pubmed] 16116077 The complete genome sequence of Mycobacterium avium subspecies paratuberculosis.(Proc. Natl. Acad. Sci. U.S.A.) [2005] |
|
51
|
Q2L6S8_9ACTO (Q2L6S8) |
|
|
3e-81 |
307 |
40% |
|
- Product
- Cytochrome P450 type compactin 3'',4''-hydroxylase
- Gene
- moxA
- Organism
- Nonomuraea recticatena
|
1uniprot[Pubmed] 16428858 Hydroxylation of testosterone by bacterial cytochromes P450 using the Escherichia coli expression system.(Biosci. Biotechnol. Biochem.) [2006] | 2uniprot[Pubmed] 17679139 Crystal structure of cytochrome P450 MoxA from Nonomuraea recticatena (CYP105).(Biochem. Biophys. Res. Commun.) [2007] | [pubmed all]
|
52
|
E4N5M4_KITSK (E4N5M4) |
|
|
3e-81 |
306 |
40% |
|
- Product
- Putative cytochrome P450
- Gene
- KSE_06650
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
53
|
C9Z4Z8_STRSW (C9Z4Z8) |
|
|
3e-81 |
306 |
42% |
|
- Product
- Putative P450-like protein
- Gene
- SCAB_11341
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
54
|
Q8KRU0_PSEAH (Q8KRU0) |
|
|
2e-80 |
304 |
40% |
|
- Product
- PauC
- Gene
- pauC
- Organism
- Pseudonocardia autotrophica
Amycolata autotrophica Nocardia autotrophica
|
1uniprot Molecular cloning and analysis of the gene for P-450 hydroxylase from Pseudonocardia autotrophica IFO12743.(J. Microbiol.) [2002] |
|
55
|
Q2L6S5_9ACTO (Q2L6S5) |
|
|
2e-80 |
304 |
42% |
|
- Product
- Cytochrome P450 type compactin 6beta-hydroxylase
- Gene
- boxA
- Organism
- Streptomyces sp. TM-7
|
1uniprot[Pubmed] 16428858 Hydroxylation of testosterone by bacterial cytochromes P450 using the Escherichia coli expression system.(Biosci. Biotechnol. Biochem.) [2006] |
|
59
|
C7QED3_CATAD (C7QED3) |
|
|
1e-79 |
301 |
40% |
|
- Product
- Cytochrome P450
- Gene
- Caci_1904
- Organism
- Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
|
1uniprot Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009] |
|
61
|
C7PXP7_CATAD (C7PXP7) |
|
|
2e-79 |
301 |
41% |
|
- Product
- Cytochrome P450
- Gene
- Caci_2582
- Organism
- Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
|
1uniprot Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009] |
|
63
|
C6W8T3_ACTMD (C6W8T3) |
|
|
3e-79 |
300 |
41% |
|
- Product
- Cytochrome P450
- Gene
- Amir_3276
- Organism
- Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
|
1uniprot Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009] |
|
64
|
D7BYL5_STRBB (D7BYL5) |
|
|
3e-79 |
300 |
43% |
|
- Product
- Putative cytochrome P450
- Gene
- cyp8
SBI_00422
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
69
|
B2HG54_MYCMM (B2HG54) |
|
|
8e-79 |
299 |
40% |
|
- Product
- Cytochrome P450 105Q4 Cyp105Q4
- Gene
- cyp105Q4
MMAR_4762
- Organism
- Mycobacterium marinum (strain ATCC BAA-535 / M)
|
1uniprot[Pubmed] 18403782 Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis.(Genome Res.) [2008] |
|
75
|
A0PL40_MYCUA (A0PL40) |
|
|
1e-77 |
295 |
40% |
|
- Product
- Cytochrome P450 105Q4 Cyp105Q4
- Gene
- cyp105Q4
MUL_0333
- Organism
- Mycobacterium ulcerans (strain Agy99)
|
1uniprot[Pubmed] 17210928 Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer.(Genome Res.) [2007] |
|
76
|
Q156A0_AMYOR (Q156A0) |
|
|
1e-77 |
295 |
39% |
|
- Product
- Epothilone b hydroxylase
- Gene
- ebh
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 16972046 Cloning and expression of a cytochrome P450 hydroxylase gene from Amycolatopsis orientalis: hydroxylation of epothilone B for the production of epothilone F.(J. Ind. Microbiol. Biotechnol.) [2007] |
|
77
|
E0D207_9ACTO (E0D207) |
|
|
8e-77 |
292 |
39% |
|
- Product
- Cytochrome P450
- Gene
- gfsF
- Organism
- Streptomyces graminofaciens
|
1uniprot[Pubmed] 20589823 Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010] |
|
78
|
C7N0B0_SACVD (C7N0B0) |
|
|
1e-76 |
291 |
38% |
|
- Product
- Cytochrome P450
- Gene
- Svir_33480
- Organism
- Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
|
1uniprot Complete genome sequence of Saccharomonospora viridis type strain (P101T).(Stand. Genomic Sci.) [2009] |
|
79
|
Q595R4_9ACTO (Q595R4) |
|
|
1e-76 |
291 |
41% |
|
- Product
- Cytochrome P450 monooxygenase CYP105B2
- Gene
- cyp229
- Organism
- Streptomyces tubercidicus
|
1uniprot[Pubmed] 16269732 Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005] | 2uniprot[Pubmed] 16269733 Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.(Appl. Environ. Microbiol.) [2005] | [pubmed all]
|
80
|
D0U2E9_STRPT (D0U2E9) |
|
|
2e-76 |
291 |
41% |
|
- Product
- Hydroxylase
- Gene
-
- Organism
- Streptomyces platensis subsp. rosaceus
|
1uniprot[Pubmed] 19726666 iso-Migrastatin, migrastatin, and dorrigocin production in Streptomyces platensis NRRL 18993 is governed by a single biosynthetic machinery featuring an acyltransferase-less type I polyketide synthase.(J. Biol. Chem.) [2009] |
|
83
|
Q6TEI1_STRDI (Q6TEI1) |
|
|
4e-76 |
290 |
41% |
|
- Product
- Cytochrome P450 monooxygenase
- Gene
- mnp1
- Organism
- Streptomyces diastaticus
|
1uniprot[Pubmed] 15123265 Starter unit choice determines the production of two tetraene macrolides, rimocidin and CE-108, in Streptomyces diastaticus var. 108.(Chem. Biol.) [2004] |
|
84
|
CPXF_STRGO (P18327) |
|
|
5e-76 |
290 |
41% |
|
- Product
- Cytochrome P450-SU2
CYP105B1 Cytochrome P450-CVB1
- Gene
- CYP105B1
subC
- Organism
- Streptomyces griseolus
|
1uniprot[Pubmed] 2345149 [Medline] 90264332 Genes for two herbicide-inducible cytochromes P-450 from Streptomyces griseolus.(J. Bacteriol.) [1990] |
|
85
|
D8I6K7_AMYMU (D8I6K7) |
|
|
8e-76 |
288 |
39% |
|
- Product
- Cytochrome P450
- Gene
- AMED_7211
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
87
|
F4F7G4_VERMA (F4F7G4) |
|
|
1e-75 |
288 |
42% |
|
- Product
- Cytochrome P450
- Gene
- VAB18032_16485
- Organism
- Verrucosispora maris (strain AB-18-032)
|
1uniprot[Pubmed] 21551311 Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011] |
|
88
|
Q825I8_STRAW (Q825I8) |
|
|
2e-75 |
288 |
40% |
|
- Product
- Cytochrome P450 hydroxylase
- Gene
- cyp28
SAV7469 SAV_7469
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
89
|
Q79ZT5_STRAW (Q79ZT5) |
|
|
2e-75 |
287 |
40% |
|
- Product
- Cytochrome P450 hydroxylase
- Gene
- pteD
SAV412 SAV_412
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
90
|
Q93H80_STRAW (Q93H80) |
|
|
2e-75 |
287 |
40% |
|
- Product
- Cytochrome P450
- Gene
- pteD
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 20375018 Regio- and stereospecificity of filipin hydroxylation sites revealed by crystal structures of cytochrome P450 105P1 and 105D6 from Streptomyces avermitilis.(J. Biol. Chem.) [2010] | [pubmed all]
|
92
|
D8I293_AMYMU (D8I293) |
|
|
6e-75 |
286 |
37% |
|
- Product
- Cytochrome P450
- Gene
- AMED_0875
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
93
|
D7B189_NOCDD (D7B189) |
|
|
6e-75 |
286 |
40% |
|
- Product
- Cytochrome P450
- Gene
- Ndas_1037
- Organism
- Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei
|
1uniprot Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010] |
|
94
|
Q8KNC8_MICEC (Q8KNC8) |
|
|
8e-75 |
285 |
39% |
|
- Product
- CalE10
- Gene
- calE10
- Organism
- Micromonospora echinospora
Micromonospora purpurea
|
1uniprot[Pubmed] 12183629 [Medline] 22171414 The calicheamicin gene cluster and its iterative type I enediyne PKS.(Science) [2002] |
|
97
|
D8I8M5_AMYMU (D8I8M5) |
|
|
1e-74 |
285 |
40% |
|
- Product
- Cytochrome P450
- Gene
- AMED_3577
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
99
|
B3XWK3_9ACTO (B3XWK3) |
|
|
5e-74 |
283 |
40% |
|
- Product
- Cytochrome P450 monooxygenase
- Gene
- psmA
- Organism
- Streptomyces sp. A-1544
|
1uniprot[Pubmed] 18640605 Increase in pladienolide D production rate using a Streptomyces strain overexpressing a cytochrome P450 gene.(J. Biosci. Bioeng.) [2008] |
|