| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
Q6YL50_9ACTO (Q6YL50) |
|
|
0.0 |
931 |
100% |
|
- Product
- Cytochrome P450 hydroxylase
- Gene
- meiE
- Organism
- Streptomyces nanchangensis
|
1uniprot[Pubmed] 12811466 [Medline] 22777186 Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003] | 2uniprot[Pubmed] 20348291 Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010] | [pubmed all]
|
2
|
D7C427_STRBB (D7C427) |
|
|
0.0 |
929 |
100% |
|
- Product
- Cytochrome P450 hydroxylase
- Gene
- milE
SBI_00728
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
3
|
Q9S0R5_STRAW (Q9S0R5) |
|
|
1e-155 |
554 |
62% |
|
- Product
- Cytochrome P450 hydroxylase
- Gene
- aveE
SAV941 SAV_941
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 10449723 [Medline] 99380548 Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis.(Proc. Natl. Acad. Sci. U.S.A.) [1999] | 2uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 3uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
5
|
D8HSD6_AMYMU (D8HSD6) |
|
|
2e-88 |
331 |
43% |
|
- Product
- Cytochrome P450
- Gene
- AMED_4350
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
6
|
C9K1X6_9ACTO (C9K1X6) |
|
|
3e-85 |
320 |
43% |
|
- Product
- P450
- Gene
-
- Organism
- Streptomyces melanosporofaciens
|
1uniprot Cloning and Heterologous Expression of the Cyclooctatin Biosynthetic Gene Cluster Afford a Diterpene Cyclase and Two P450 Hydroxylases.(Chem. Biol.) [2008] |
|
8
|
D8HY97_AMYMU (D8HY97) |
|
|
5e-83 |
313 |
39% |
|
- Product
- Cytochrome P450
- Gene
- AMED_4819
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
9
|
D8HJ08_AMYMU (D8HJ08) |
|
|
6e-83 |
313 |
42% |
|
- Product
- Cytochrome P450
- Gene
- AMED_8280
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
13
|
C9K1X7_9ACTO (C9K1X7) |
|
|
3e-80 |
303 |
41% |
|
- Product
- P450
- Gene
-
- Organism
- Streptomyces melanosporofaciens
|
1uniprot Cloning and Heterologous Expression of the Cyclooctatin Biosynthetic Gene Cluster Afford a Diterpene Cyclase and Two P450 Hydroxylases.(Chem. Biol.) [2008] |
|
16
|
D5SJH2_STRCL (D5SJH2) |
|
|
8e-75 |
286 |
39% |
|
- Product
- Pentalenene C13 hydroxylase
- Gene
- SCLAV_p0576
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot The sequence of a 1.8 Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
19
|
E3VWK7_STREX (E3VWK7) |
|
|
8e-73 |
279 |
36% |
|
- Product
- PenI
- Gene
- penI
- Organism
- Streptomyces exfoliatus
Streptomyces hydrogenans
|
1uniprot[Pubmed] 21284395 Genome mining in streptomyces. Discovery of an unprecedented P450-catalyzed oxidative rearrangement that is the final step in the biosynthesis of pentalenolactone.(J. Am. Chem. Soc.) [2011] |
|
20
|
Q82IY3_STRAW (Q82IY3) |
|
|
7e-72 |
276 |
38% |
|
- Product
- Pentalenene C13 hydroxylase; cytochrome P450
- Gene
- ptlI
SAV2999 SAV_2999
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
22
|
D7BUS9_STRBB (D7BUS9) |
|
|
5e-69 |
266 |
37% |
|
- Product
- Cytochrome P450
- Gene
- cyp1
SBI_00149
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
23
|
D7CBC1_STRBB (D7CBC1) |
|
|
1e-68 |
265 |
36% |
|
- Product
- Cytochrome P450
- Gene
- cyp48
SBI_09680
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
26
|
Q70AR1_STRPE (Q70AR1) |
|
|
1e-67 |
261 |
38% |
|
- Product
- Putative cytochrome P450
- Gene
- cyp0759
- Organism
- Streptomyces peucetius
|
1uniprot[Pubmed] 15111132 Genome analyses of Streptomyces peucetius ATCC 27952 for the identification and comparison of cytochrome P450 complement with other Streptomyces.(Arch. Biochem. Biophys.) [2004] |
|
27
|
B2HKP3_MYCMM (B2HKP3) |
|
|
2e-67 |
261 |
37% |
|
- Product
- Cytochrome P450 183B1 Cyp183B1
- Gene
- cyp183B1
MMAR_0281
- Organism
- Mycobacterium marinum (strain ATCC BAA-535 / M)
|
1uniprot[Pubmed] 18403782 Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis.(Genome Res.) [2008] |
|
29
|
E3VWJ1_STRAE (E3VWJ1) |
|
|
7e-67 |
259 |
36% |
|
- Product
- PntI
- Gene
- pntI
- Organism
- Streptomyces arenae
|
1uniprot[Pubmed] 21284395 Genome mining in streptomyces. Discovery of an unprecedented P450-catalyzed oxidative rearrangement that is the final step in the biosynthesis of pentalenolactone.(J. Am. Chem. Soc.) [2011] |
|
30
|
D5SI17_STRCL (D5SI17) |
|
|
2e-66 |
258 |
37% |
|
- Product
- Cytochrome P450
- Gene
- SCLAV_p0067
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot The sequence of a 1.8 Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
31
|
B5GZC3_STRCL (B5GZC3) |
|
|
4e-66 |
256 |
35% |
|
- Product
- Pentalenene C13 hydroxylase
Pentalenene C13 hydroxylase cytochrome P450
- Gene
- SCLAV_5670
SSCG_04697
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot[Pubmed] 20624727 The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
34
|
E2Q1P0_STRCL (E2Q1P0) |
|
|
7e-64 |
249 |
36% |
|
- Product
- Putative cytochrome P450
- Gene
- SCLAV_5599
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot[Pubmed] 20624727 The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
35
|
D3Y183_STRPT (D3Y183) |
|
|
2e-63 |
248 |
35% |
|
- Product
- Putative cytoplasmic protein
- Gene
-
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 20067498 Coevolution of antibiotic production and counter-resistance in soil bacteria.(Environ. Microbiol.) [2010] |
|
36
|
B2HKP5_MYCMM (B2HKP5) |
|
|
2e-63 |
248 |
35% |
|
- Product
- Cytochrome P450 274A1 Cyp274A1
- Gene
- cyp274A1
MMAR_0283
- Organism
- Mycobacterium marinum (strain ATCC BAA-535 / M)
|
1uniprot[Pubmed] 18403782 Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis.(Genome Res.) [2008] |
|
37
|
D7BUT0_STRBB (D7BUT0) |
|
|
3e-63 |
247 |
37% |
|
- Product
- Cytochrome P450
- Gene
- cyp2
SBI_00150
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
39
|
C1F4E6_ACIC5 (C1F4E6) |
|
|
6e-63 |
246 |
33% |
|
- Product
- Cytochrome P450 family protein
- Gene
- ACP_2988
- Organism
- Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670)
|
1uniprot[Pubmed] 19201974 Three genomes from the phylum Acidobacteria provide insight into the lifestyles of these microorganisms in soils.(Appl. Environ. Microbiol.) [2009] |
|
41
|
B5H2T2_STRCL (B5H2T2) |
|
|
1e-62 |
245 |
34% |
|
- Product
- Cytochrome P450 hydroxylase
- Gene
- SCLAV_p0664
SSCG_05861
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot The sequence of a 1.8 Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
43
|
C7QAD6_CATAD (C7QAD6) |
|
|
3e-62 |
244 |
36% |
|
- Product
- Cytochrome P450
- Gene
- Caci_3529
- Organism
- Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
|
1uniprot Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009] |
|
44
|
E4N8U7_KITSK (E4N8U7) |
|
|
4e-62 |
243 |
39% |
|
- Product
- Putative cytochrome P450
- Gene
- KSE_18030
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
45
|
A3KIJ0_STRAM (A3KIJ0) |
|
|
1e-61 |
241 |
36% |
|
- Product
- Putative cytochrome P450
- Gene
- SAML0538
- Organism
- Streptomyces ambofaciens ATCC 23877
|
1uniprot[Pubmed] 16956972 Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006] |
|
46
|
Q5KSN6_9ACTO (Q5KSN6) |
|
|
3e-61 |
240 |
35% |
|
- Product
- Putative P450
- Gene
- p450
- Organism
- Streptomyces sp. KO-3988
|
1uniprot[Pubmed] 15712669 Presence of copalyl diphosphate synthase gene in an actinomycete possessing the mevalonate pathway.(J. Antibiot.) [2004] |
|
48
|
B5GS25_STRCL (B5GS25) |
|
|
7e-61 |
239 |
34% |
|
- Product
- Cytochrome P450 hydroxylase
- Gene
- SCLAV_p0327
SSCG_02149
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot The sequence of a 1.8 Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
55
|
E4N4S6_KITSK (E4N4S6) |
|
|
3e-59 |
234 |
35% |
|
- Product
- Putative cytochrome P450
- Gene
- KSE_03600
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
56
|
D7BWI7_STRBB (D7BWI7) |
|
|
2e-58 |
231 |
34% |
|
- Product
- Cytochrome P450
- Gene
- cyp4
SBI_00222
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
61
|
E5DHP9_STRGB (E5DHP9) |
|
|
1e-57 |
229 |
34% |
|
- Product
- Monooxygenase
- Gene
-
- Organism
- Streptomyces galbus
|
1uniprot[Pubmed] 20662933 The methoxymalonyl-acyl carrier protein biosynthesis locus and the nearby gene with the beta-ketoacyl synthase domain are involved in the biosynthesis of galbonolides in Streptomyces galbus, but these loci are separate from the modular polyketide synthase gene cluster.(FEMS Microbiol. Lett.) [2010] |
|
62
|
D8HQA3_AMYMU (D8HQA3) |
|
|
2e-57 |
228 |
34% |
|
- Product
- Cytochrome P450
- Gene
- AMED_7819
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
67
|
E4MZ16_KITSK (E4MZ16) |
|
|
4e-56 |
223 |
34% |
|
- Product
- Putative cytochrome P450
- Gene
- KSE_00570t
KSE_76170t
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
68
|
D5SJG9_STRCL (D5SJG9) |
|
|
6e-56 |
223 |
35% |
|
- Product
- Cytochrome P450
- Gene
- SCLAV_p0573
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot The sequence of a 1.8 Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
71
|
Q9K498_STRCO (Q9K498) |
|
|
8e-56 |
222 |
34% |
|
- Product
- Putative cytochrome P450
- Gene
- SCO5223
- Organism
- Streptomyces coelicolor
|
1uniprot[Pubmed] 12000953 [Medline] 21996410 Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002] | 2uniprot[Pubmed] 19858213 Crystal structure of albaflavenone monooxygenase containing a moonlighting terpene synthase active site.(J. Biol. Chem.) [2009] | [pubmed all]
|
72
|
E4NVP0_HALBP (E4NVP0) |
|
|
9e-56 |
222 |
33% |
|
- Product
- Cytochrome P450
- Gene
- Hbor_34020
- Organism
- Halogeometricum borinquense (strain ATCC 700274 / DSM 11551 / JCM 10706 / PR3)
|
1uniprot[Pubmed] 21304651 Complete genome sequence of Halogeometricum borinquense type strain (PR3).(Stand. Genomic Sci.) [2009] |
|
73
|
C7Q393_CATAD (C7Q393) |
|
|
1e-55 |
222 |
33% |
|
- Product
- Cytochrome P450
- Gene
- Caci_4969
- Organism
- Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
|
1uniprot Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009] |
|
75
|
B1VU64_STRGG (B1VU64) |
|
|
2e-55 |
221 |
34% |
|
- Product
- Putative cytochrome P450
- Gene
- SGR_1079
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
77
|
D5SJX6_STRCL (D5SJX6) |
|
|
4e-55 |
220 |
35% |
|
- Product
- Cytochrome P450
- Gene
- SCLAV_p0732
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot The sequence of a 1.8 Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
78
|
A8KZF9_FRASN (A8KZF9) |
|
|
7e-55 |
219 |
35% |
|
- Product
- Cytochrome P450
- Gene
- Franean1_5157
- Organism
- Frankia sp. (strain EAN1pec)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
79
|
E2Q1J0_STRCL (E2Q1J0) |
|
|
2e-54 |
218 |
33% |
|
- Product
- Cytochrome P450
- Gene
- SCLAV_5549
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot[Pubmed] 20624727 The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
80
|
B9XNM0_9BACT (B9XNM0) |
|
|
3e-54 |
217 |
32% |
|
- Product
- Cytochrome P450
- Gene
- Cflav_PD1750
- Organism
- Pedosphaera parvula Ellin514
|
1uniprot[Pubmed] 21460084 Genome Sequence of 'Pedosphaera parvula' Ellin514, an Aerobic Verrucomicrobial Isolate from Pasture Soil.(J. Bacteriol.) [2011] |
|
81
|
B5GRC6_STRCL (B5GRC6) |
|
|
5e-54 |
216 |
35% |
|
- Product
- Pentalenene C13 hydroxylase
- Gene
- SCLAV_p0489
SSCG_01900
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot The sequence of a 1.8 Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
83
|
F2RDW9_STRVP (F2RDW9) |
|
|
1e-53 |
216 |
34% |
|
- Product
- Putative uncharacterized protein SVEN_1222
- Gene
- SVEN_1222
- Organism
- Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
|
1uniprot[Pubmed] 21463507 Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011] |
|
87
|
Q2J4I2_FRASC (Q2J4I2) |
|
|
3e-53 |
214 |
34% |
|
- Product
- Cytochrome P450
- Gene
- Francci3_4464
- Organism
- Frankia sp. (strain CcI3)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
91
|
F3NMW9_9ACTO (F3NMW9) |
|
|
1e-52 |
212 |
34% |
|
- Product
- Cytochrome P450
- Gene
- SGM_4483
- Organism
- Streptomyces griseoaurantiacus M045
|
1uniprot[Pubmed] 21551298 Draft Genome Sequence of the Marine Bacterium Streptomyces griseoaurantiacus M045, Which Produces Novel Manumycin-Type Antibiotics with a pABA Core Component.(J. Bacteriol.) [2011] |
|
92
|
Q2T2R5_BURTA (Q2T2R5) |
|
|
2e-52 |
211 |
33% |
|
- Product
- Cytochrome P450-related protein
- Gene
- BTH_II2347
- Organism
- Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301)
|
1uniprot[Pubmed] 16336651 Bacterial genome adaptation to niches: divergence of the potential virulence genes in three Burkholderia species of different survival strategies.(BMC Genomics) [2005] |
|
97
|
Q9KFA6_BACHD (Q9KFA6) |
|
|
6e-52 |
209 |
29% |
|
- Product
- Cytochrome P450 hydroxylase
- Gene
- BH0579
- Organism
- Bacillus halodurans
|
1uniprot[Pubmed] 11058132 [Medline] 20512582 Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis.(Nucleic Acids Res.) [2000] |
|
100
|
D5SL67_STRCL (D5SL67) |
|
|
7e-52 |
209 |
33% |
|
- Product
- Cytochrome P450
- Gene
- SCLAV_p1174
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot The sequence of a 1.8 Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|