| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
C0JWD4_9ACTO (C0JWD4) |
|
|
0.0 |
995 |
100% |
|
- Product
- PokO4
- Gene
- pokO4
- Organism
- Streptomyces diastatochromogenes
|
1uniprot[Pubmed] 19266534 Organisation of the Biosynthetic Gene Cluster and Tailoring Enzymes in the Biosynthesis of the Tetracyclic Quinone Glycoside Antibiotic Polyketomycin.(Chembiochem) [2009] |
|
3
|
Q3S8P7_STRRM (Q3S8P7) |
|
|
1e-102 |
378 |
46% |
|
- Product
- OxyS
- Gene
- oxyS
- Organism
- Streptomyces rimosus
|
1uniprot[Pubmed] 16597959 Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase.(Appl. Environ. Microbiol.) [2006] |
|
5
|
Q58PK7_STRRM (Q58PK7) |
|
|
1e-100 |
369 |
46% |
|
- Product
- Anhydrotetracycline oxygenase
- Gene
- otcC
- Organism
- Streptomyces rimosus
|
1uniprot[Pubmed] 16148009 Ablation of the otcC gene encoding a post-polyketide hydroxylase from the oxytetracyline biosynthetic pathway in Streptomyces rimosus results in novel polyketides with altered chain length.(J. Biol. Chem.) [2005] |
|
6
|
Q8KSX5_9ACTO (Q8KSX5) |
|
|
1e-99 |
368 |
47% |
|
- Product
- Putative FAD-dependent monooxygenase GrhO6
- Gene
- grhO6
- Organism
- Streptomyces sp. JP95
|
1uniprot[Pubmed] 12323376 [Medline] 22235582 A gene cluster from a marine Streptomyces encoding the biosynthesis of the aromatic spiroketal polyketide griseorhodin A.(Chem. Biol.) [2002] |
|
7
|
Q0RMN5_FRAAA (Q0RMN5) |
|
|
8e-98 |
362 |
46% |
|
- Product
- Putative polyketide oxygenase/hydroxylase
- Gene
- FRAAL2565
- Organism
- Frankia alni (strain ACN14a)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
8
|
Q47QL5_THEFY (Q47QL5) |
|
|
5e-97 |
359 |
46% |
|
- Product
- Putative uncharacterized protein
- Gene
- Tfu_1216
- Organism
- Thermobifida fusca (strain YX)
|
1uniprot[Pubmed] 17209016 Genome sequence and analysis of the soil cellulolytic actinomycete Thermobifida fusca YX.(J. Bacteriol.) [2007] |
|
9
|
C4NYK4_9ACTO (C4NYK4) |
|
|
8e-97 |
359 |
47% |
|
- Product
- SaqM
- Gene
- saqM
- Organism
- Micromonospora sp. Tu 6368
|
1uniprot[Pubmed] 17497146 A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007] | 2uniprot[Pubmed] 19384899 Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009] | [pubmed all]
|
10
|
D3UA07_9ACTO (D3UA07) |
|
|
5e-96 |
356 |
45% |
|
- Product
- FAD-dependent monooxygenase
- Gene
-
- Organism
- Streptomyces flaveolus
|
1uniprot Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010] |
|
12
|
F4FF57_VERMA (F4FF57) |
|
|
3e-95 |
354 |
46% |
|
- Product
- FAD-dependent monooxygenase
- Gene
- VAB18032_19300
- Organism
- Verrucosispora maris (strain AB-18-032)
|
1uniprot[Pubmed] 21551311 Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011] |
|
13
|
Q5YTV5_NOCFA (Q5YTV5) |
|
|
6e-95 |
352 |
46% |
|
- Product
- Putative rifampin monooxygenase
- Gene
- rox
NFA_35380
- Organism
- Nocardia farcinica
|
1uniprot[Pubmed] 15466710 The complete genomic sequence of Nocardia farcinica IFM 10152.(Proc. Natl. Acad. Sci. U.S.A.) [2004] |
|
21
|
A8L729_FRASN (A8L729) |
|
|
2e-93 |
348 |
45% |
|
- Product
- Pentachlorophenol monooxygenase
- Gene
- Franean1_4133
- Organism
- Frankia sp. (strain EAN1pec)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
22
|
Q8KU28_9NOCA (Q8KU28) |
|
|
3e-93 |
347 |
46% |
|
- Product
- Flavin-type hydroxylase
- Gene
-
- Organism
- Rhodococcus sp. NCIMB 9784
|
1uniprot[Pubmed] 12081961 [Medline] 22077259 Identification of a new class of cytochrome P450 from a Rhodococcus sp.(J. Bacteriol.) [2002] |
|
23
|
A4FIN7_SACEN (A4FIN7) |
|
|
1e-92 |
345 |
46% |
|
- Product
- Monooxygenase, FAD-binding protein
- Gene
- SACE_4643
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
25
|
D2B5V9_STRRD (D2B5V9) |
|
|
2e-92 |
344 |
45% |
|
- Product
- Putative monooxygenase
- Gene
- Sros_8778
- Organism
- Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
|
1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010] |
|
32
|
A9FKP5_SORC5 (A9FKP5) |
|
|
1e-91 |
342 |
45% |
|
- Product
- Putative monooxygenase
- Gene
- yhjG3
sce4973
- Organism
- Sorangium cellulosum (strain So ce56)
Polyangium cellulosum (strain So ce56)
|
1uniprot[Pubmed] 17965706 Complete genome sequence of the myxobacterium Sorangium cellulosum.(Nat. Biotechnol.) [2007] |
|
34
|
Q0S0L2_RHOSR (Q0S0L2) |
|
|
4e-91 |
340 |
45% |
|
- Product
- Probable FAD-dependent monooxygenase
- Gene
- RHA1_ro07160
- Organism
- Rhodococcus sp. (strain RHA1)
|
1uniprot[Pubmed] 17030794 The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse.(Proc. Natl. Acad. Sci. U.S.A.) [2006] |
|
35
|
F3NH12_9ACTO (F3NH12) |
|
|
4e-91 |
340 |
46% |
|
- Product
- FAD-dependent monooxygenase
- Gene
- SGM_2426
- Organism
- Streptomyces griseoaurantiacus M045
|
1uniprot[Pubmed] 21551298 Draft Genome Sequence of the Marine Bacterium Streptomyces griseoaurantiacus M045, Which Produces Novel Manumycin-Type Antibiotics with a pABA Core Component.(J. Bacteriol.) [2011] |
|
40
|
D2ASL9_STRRD (D2ASL9) |
|
|
3e-90 |
337 |
45% |
|
- Product
- Putative monooxygenase
- Gene
- Sros_5796
- Organism
- Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
|
1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010] |
|
44
|
F2RC22_STRVP (F2RC22) |
|
|
4e-90 |
337 |
43% |
|
- Product
- 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
- Gene
- SVEN_5987
- Organism
- Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
|
1uniprot[Pubmed] 21463507 Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011] |
|
47
|
Q194P4_STRAA (Q194P4) |
|
|
8e-90 |
335 |
47% |
|
- Product
- Oxygenase
- Gene
- mtmOIV
- Organism
- Streptomyces argillaceus
|
1uniprot[Pubmed] 8654997 [Medline] 96257259 Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996] | 2uniprot[Pubmed] 8757400 [Medline] 96335144 An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996] | 3uniprot[Pubmed] 9150235 [Medline] 97294479 Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997] | 4uniprot[Pubmed] 9733697 [Medline] 98406047 Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998] | 5uniprot[Pubmed] 10102355 [Medline] 99200478 Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999] | 6uniprot[Pubmed] 9889148 [Medline] 99111236 Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999] | 7uniprot[Pubmed] 10660060 [Medline] 20123456 Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000] | 8uniprot[Pubmed] 11254130 [Medline] 21148776 The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001] | 9uniprot[Pubmed] 12733914 [Medline] 22619809 Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003] | 10uniprot[Pubmed] 9917296 [Medline] 99115752 The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999] | 11uniprot[Pubmed] 11853433 [Medline] 21843297 Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002] | 12uniprot[Pubmed] 10652287 [Medline] 20119254 Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000] | 13uniprot[Pubmed] 10779713 [Medline] 20243461 Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000] | 14uniprot[Pubmed] 12022840 [Medline] 22017994 Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002] | 15uniprot[Pubmed] 12813091 [Medline] 22697398 Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003] | 16uniprot[Pubmed] 8807845 [Medline] 97113238 Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996] | 17uniprot[Pubmed] 14660589 MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004] | 18uniprot[Pubmed] 9375253 [Medline] 98042823 Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997] | 19uniprot[Pubmed] 15712316 Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005] | 20uniprot[Pubmed] 10760873 The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000] | 21uniprot[Pubmed] 19364090 Crystal structure of Baeyer-Villiger monooxygenase MtmOIV, the key enzyme of the mithramycin biosynthetic pathway .(Biochemistry) [2009] | [pubmed all]
|
51
|
Q1RQU9_STRAM (Q1RQU9) |
|
|
2e-89 |
335 |
43% |
|
- Product
- Putative oxygenase
- Gene
- SAMT0136
SAMT0137
- Organism
- Streptomyces ambofaciens ATCC 23877
|
1uniprot[Pubmed] 16952952 Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006] | 2uniprot[Pubmed] 16956972 Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006] | 3uniprot Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006] | [pubmed all]
|
53
|
F2R776_STRVP (F2R776) |
|
|
2e-89 |
334 |
44% |
|
- Product
- Rifampin monooxygenase
- Gene
- SVEN_0481
- Organism
- Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
|
1uniprot[Pubmed] 21463507 Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011] |
|
55
|
E4W9I8_RHOE1 (E4W9I8) |
|
|
3e-89 |
334 |
43% |
|
- Product
- FAD-dependent monooxygenase
- Gene
- REQ_41440
- Organism
- Rhodococcus equi (strain 103S)
Corynebacterium equi
|
1uniprot[Pubmed] 20941392 The genome of a pathogenic rhodococcus: cooptive virulence underpinned by key gene acquisitions.(PLoS Genet.) [2010] |
|
56
|
Q53657_STRAU (Q53657) |
|
|
5e-89 |
333 |
46% |
|
- Product
- 6-hydroxylation enzyme of tetracycline
- Gene
- cts8
- Organism
- Streptomyces aureofaciens
|
1uniprot[Pubmed] 7612997 [Medline] 95337551 Cloning and nucleotide sequence of the gene responsible for chlorination of tetracycline.(Biosci. Biotechnol. Biochem.) [1995] |
|
57
|
Q9S1P2_STRCO (Q9S1P2) |
|
|
5e-89 |
333 |
44% |
|
- Product
- Putative monooxygenase
- Gene
- SCO0249
- Organism
- Streptomyces coelicolor
|
1uniprot[Pubmed] 12000953 [Medline] 21996410 Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002] |
|
58
|
Q5U913_9ACTO (Q5U913) |
|
|
7e-89 |
332 |
43% |
|
- Product
- JadH
- Gene
- jadH
- Organism
- Streptomyces venezuelae
|
1uniprot[Pubmed] 15817470 Functional analyses of oxygenases in jadomycin biosynthesis and identification of JadH as a bifunctional oxygenase/dehydrase.(J. Biol. Chem.) [2005] |
|
59
|
Q0JWC9_STRAM (Q0JWC9) |
|
|
7e-89 |
332 |
43% |
|
- Product
- Putative oxygenase
- Gene
- DSMT0156
- Organism
- Streptomyces ambofaciens
|
1uniprot[Pubmed] 16952952 Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006] |
|
61
|
D7AZP0_NOCDD (D7AZP0) |
|
|
8e-89 |
332 |
46% |
|
- Product
- Monooxygenase FAD-binding protein
- Gene
- Ndas_2748
- Organism
- Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei
|
1uniprot Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010] |
|
62
|
B3TMQ4_9ACTO (B3TMQ4) |
|
|
1e-88 |
332 |
42% |
|
- Product
- FAD-dependent oxidoreductase
- Gene
- KijA
- Organism
- Actinomadura kijaniata
|
1uniprot[Pubmed] 17985890 Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007] |
|
65
|
D2XDX3_9PSEU (D2XDX3) |
|
|
4e-88 |
330 |
42% |
|
- Product
- AzicO3
- Gene
- azicO3
- Organism
- Kibdelosporangium sp. MJ126-NF4
|
1uniprot[Pubmed] 19928906 Biosynthetic studies of aziridine formation in azicemicins.(J. Am. Chem. Soc.) [2009] |
|
66
|
D5SK10_STRCL (D5SK10) |
|
|
5e-88 |
330 |
45% |
|
- Product
- Monooxygenase, FAD-binding protein
- Gene
- SCLAV_p0766
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot The sequence of a 1.8 Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
67
|
Q65K23_BACLD (Q65K23) |
|
|
8e-88 |
329 |
40% |
|
- Product
- Putative Flavoprotein monooxygenase
YhjG
- Gene
- yhjG
BL02996 BLi01695
- Organism
- Bacillus licheniformis (strain DSM 13 / ATCC 14580)
|
1uniprot[Pubmed] 15383718 The complete genome sequence of Bacillus licheniformis DSM13, an organism with great industrial potential.(J. Mol. Microbiol. Biotechnol.) [2004] | 2uniprot[Pubmed] 15461803 Complete genome sequence of the industrial bacterium Bacillus licheniformis and comparisons with closely related Bacillus species.(Genome Biol.) [2004] | [pubmed all]
|
70
|
Q2HR18_9ACTO (Q2HR18) |
|
|
1e-87 |
328 |
43% |
|
- Product
- Putative oxygenase
- Gene
- schP10
- Organism
- Streptomyces sp. SCC 2136
|
1uniprot Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: Cloning, Sequencing, and Characterization.(Mol. Cells) [2006] | 2uniprot Molecular cloning and characterization of biosynthetic genes cluster of Sch 47554 from Streptomyces sp. SCC 2136. [2004] |
|
74
|
Q9ZGD9_STRCY (Q9ZGD9) |
|
|
2e-87 |
327 |
44% |
|
- Product
- Oxygenase homolog
- Gene
- lanE
- Organism
- Streptomyces cyanogenus
|
1uniprot[Pubmed] 9933932 [Medline] 99132695 Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis.(FEMS Microbiol. Lett.) [1999] |
|
75
|
Q47KZ8_THEFY (Q47KZ8) |
|
|
2e-87 |
327 |
43% |
|
- Product
- Putative rifampin monooxygenase
- Gene
- Tfu_2841
- Organism
- Thermobifida fusca (strain YX)
|
1uniprot[Pubmed] 17209016 Genome sequence and analysis of the soil cellulolytic actinomycete Thermobifida fusca YX.(J. Bacteriol.) [2007] |
|
76
|
Q93FA8_STRAT (Q93FA8) |
|
|
3e-87 |
327 |
44% |
|
- Product
- Sim7
- Gene
- sim7
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 12115055 [Medline] 22109063 Cloning and analysis of the simocyclinone biosynthetic gene cluster of Streptomyces antibioticus Tu 6040.(Arch. Microbiol.) [2002] |
|
78
|
E4N5W7_KITSK (E4N5W7) |
|
|
9e-87 |
325 |
46% |
|
- Product
- Putative monooxygenase
- Gene
- KSE_07580
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
79
|
Q1RQU6_STRAM (Q1RQU6) |
|
|
1e-86 |
325 |
43% |
|
- Product
- Putative oxygenase
- Gene
- SAMT0139
SAMT0140
- Organism
- Streptomyces ambofaciens ATCC 23877
|
1uniprot[Pubmed] 16952952 Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006] | 2uniprot[Pubmed] 16956972 Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006] | 3uniprot Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006] | [pubmed all]
|
81
|
Q0JWC6_STRAM (Q0JWC6) |
|
|
2e-86 |
324 |
43% |
|
- Product
- Putative oxygenase
- Gene
- DSMT0159
- Organism
- Streptomyces ambofaciens
|
1uniprot[Pubmed] 16952952 Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006] |
|
82
|
C6WFM6_ACTMD (C6WFM6) |
|
|
3e-86 |
323 |
44% |
|
- Product
- Monooxygenase FAD-binding
- Gene
- Amir_2013
- Organism
- Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
|
1uniprot Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009] |
|
83
|
C4NYJ7_9ACTO (C4NYJ7) |
|
|
4e-86 |
323 |
43% |
|
- Product
- SaqE
- Gene
- saqE
- Organism
- Micromonospora sp. Tu 6368
|
1uniprot[Pubmed] 17497146 A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007] | 2uniprot[Pubmed] 19384899 Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009] | [pubmed all]
|
86
|
Q56HA5_STRAU (Q56HA5) |
|
|
5e-86 |
323 |
43% |
|
- Product
- Aur1A
- Gene
- aur1A
- Organism
- Streptomyces aureofaciens
|
1uniprot[Pubmed] 12384301 [Medline] 22271582 Cloning and characterization of a polyketide synthase gene cluster involved in biosynthesis of a proposed angucycline-like polyketide auricin in Streptomyces aureofaciens CCM 3239.(Gene) [2002] | 2uniprot[Pubmed] 16079347 Characterization of a regulatory gene essential for the production of the angucycline-like polyketide antibiotic auricin in Streptomyces aureofaciens CCM 3239.(Microbiology) [2005] | 3uniprot[Pubmed] 20466770 The role of the TetR-family transcriptional regulator Aur1R in negative regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2010] | [pubmed all]
|
89
|
Q93LY7_9ACTO (Q93LY7) |
|
|
8e-86 |
322 |
42% |
|
- Product
- Polyketide oxygenase PgaE
- Gene
- pgaE
- Organism
- Streptomyces sp. PGA64
|
1uniprot[Pubmed] 12654660 [Medline] 22540650 Engineering anthracycline biosynthesis toward angucyclines.(Antimicrob. Agents Chemother.) [2003] | 2uniprot[Pubmed] 15515887 Partial activation of a silent angucycline-type gene cluster from a rubromycin beta producing Streptomyces sp. PGA64.(J. Antibiot.) [2004] | 3uniprot[Pubmed] 17669423 Crystal structures of two aromatic hydroxylases involved in the early tailoring steps of angucycline biosynthesis.(J. Mol. Biol.) [2007] | [pubmed all]
|
90
|
D7RFJ3_AMYOR (D7RFJ3) |
|
|
1e-85 |
322 |
44% |
|
- Product
- Putative oxygenase
- Gene
- bexE
- Organism
- Amycolatopsis orientalis subsp. vinearia
|
1uniprot[Pubmed] 20443562 A biosynthetic pathway for BE-7585A, a 2-thiosugar-containing angucycline-type natural product.(J. Am. Chem. Soc.) [2010] |
|
91
|
Q9AMJ5_STRAT (Q9AMJ5) |
|
|
1e-85 |
322 |
43% |
|
- Product
- Putative oxygenase SimA7
- Gene
- simA7
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 11959542 [Medline] 21955989 Biosynthetic gene cluster of simocyclinone, a natural multihybrid antibiotic.(Antimicrob. Agents Chemother.) [2002] |
|
92
|
Q9F6D1_9ACTO (Q9F6D1) |
|
|
2e-85 |
321 |
42% |
|
- Product
- Oxygenase
- Gene
- zhuK
- Organism
- Streptomyces sp. R1128
|
1uniprot[Pubmed] 10931852 [Medline] 20517899 Cloning, nucleotide sequence, and heterologous expression of the biosynthetic gene cluster for R1128, a non-steroidal estrogen receptor antagonist. Insights into an unusual priming mechanism.(J. Biol. Chem.) [2000] |
|
93
|
C7QAE9_CATAD (C7QAE9) |
|
|
4e-85 |
320 |
43% |
|
- Product
- Monooxygenase FAD-binding
- Gene
- Caci_3543
- Organism
- Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
|
1uniprot Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009] |
|
95
|
D6MSW1_9ACTO (D6MSW1) |
|
|
4e-85 |
320 |
43% |
|
- Product
- SsfO1
- Gene
- ssfO1
- Organism
- Streptomyces sp. SF2575
|
1uniprot[Pubmed] 19908837 Biochemical analysis of the biosynthetic pathway of an anticancer tetracycline SF2575.(J. Am. Chem. Soc.) [2009] |
|
99
|
D2XDX8_9PSEU (D2XDX8) |
|
|
1e-84 |
319 |
42% |
|
- Product
- AzicO4
- Gene
- azicO4
- Organism
- Kibdelosporangium sp. MJ126-NF4
|
1uniprot[Pubmed] 19928906 Biosynthetic studies of aziridine formation in azicemicins.(J. Am. Chem. Soc.) [2009] |
|