| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
B4XYC4_9ACTO (B4XYC4) |
|
|
0.0 |
869 |
100% |
|
- Product
- Azi32
- Gene
- azi32
- Organism
- Streptomyces sahachiroi
|
1uniprot[Pubmed] 18635006 Characterization of the azinomycin B biosynthetic gene cluster revealing a different iterative type I polyketide synthase for naphthoate biosynthesis.(Chem. Biol.) [2008] |
|
2
|
C6WLE5_ACTMD (C6WLE5) |
|
|
2e-93 |
347 |
45% |
|
- Product
- Cytochrome P450
- Gene
- Amir_4494
- Organism
- Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
|
1uniprot Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009] |
|
5
|
Q595S8_9ACTO (Q595S8) |
|
|
7e-81 |
305 |
39% |
|
- Product
- Cytochrome P450 monooxygenase CYP185A1
- Gene
- cypLB
- Organism
- Streptomyces tubercidicus
|
1uniprot[Pubmed] 16269732 Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005] | 2uniprot[Pubmed] 16269733 Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.(Appl. Environ. Microbiol.) [2005] | [pubmed all]
|
8
|
D8HVR3_AMYMU (D8HVR3) |
|
|
4e-79 |
300 |
40% |
|
- Product
- Cytochrome P450
- Gene
- AMED_6238
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
9
|
Q0RMP2_FRAAA (Q0RMP2) |
|
|
6e-79 |
299 |
39% |
|
- Product
- Cytochrome P450 monooxygenase
- Gene
- FRAAL2558
- Organism
- Frankia alni (strain ACN14a)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
10
|
D5SLK1_STRCL (D5SLK1) |
|
|
1e-76 |
291 |
40% |
|
- Product
- Cytochrome P450 monooxygenase CYP185A1
- Gene
- SCLAV_p1308
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot The sequence of a 1.8 Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
11
|
F2RDR0_STRVP (F2RDR0) |
|
|
3e-66 |
257 |
37% |
|
- Product
- Putative cytochrome P450 hydroxylase
- Gene
- SVEN_6266
- Organism
- Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
|
1uniprot[Pubmed] 21463507 Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011] |
|
12
|
F6K7H0_9ACTO (F6K7H0) |
|
|
4e-66 |
256 |
35% |
|
- Product
- Cytochrome P450
- Gene
- pyrI
- Organism
- Streptomyces pyridomyceticus
|
1uniprot[Pubmed] 21454714 Identification and Characterization of the Pyridomycin Biosynthetic Gene Cluster of Streptomyces pyridomyceticus NRRL B-2517.(J. Biol. Chem.) [2011] |
|
15
|
Q9L465_STRTE (Q9L465) |
|
|
9e-64 |
249 |
35% |
|
- Product
- NikQ protein
- Gene
- nikQ
- Organism
- Streptomyces tendae
|
1uniprot[Pubmed] 10712601 [Medline] 20177695 Molecular characterization of two genes from Streptomyces tendae Tu901 required for the formation of the 4-formyl-4-imidazolin-2-one-containing nucleoside moiety of the peptidyl nucleoside antibiotic nikkomycin.(Eur. J. Biochem.) [2000] | 2uniprot[Pubmed] 11212921 [Medline] 21080548 Molecular characterization of co-transcribed genes from Streptomyces tendae Tu901 involved in the biosynthesis of the peptidyl moiety and assembly of the peptidyl nucleoside antibiotic nikkomycin.(Mol. Gen. Genet.) [2001] | [pubmed all]
|
16
|
Q9EYL2_9ACTO (Q9EYL2) |
|
|
2e-63 |
247 |
35% |
|
- Product
- Nikkomycin biosynthesis protein SanQ
- Gene
- sanQ
- Organism
- Streptomyces ansochromogenes
|
1uniprot[Pubmed] 12177738 [Medline] 22165969 Cloning and function of sanQ: a gene involved in nikkomycin biosynthesis of Streptomyces ansochromogenes.(Curr. Microbiol.) [2002] | 2uniprot[Pubmed] 12732945 [Medline] 22617878 Structure and Function of sanV: a gene involved in nikkomycin biosynthesis of Streptomyces ansochromogenes.(Curr. Microbiol.) [2003] | 3uniprot[Pubmed] 15297918 Cloning, function, and expression of sanS: a gene essential for nikkomycin biosynthesis of Streptomyces ansochromogenes.(Curr. Microbiol.) [2004] | [pubmed all]
|
18
|
Q0X0B3_STRLS (Q0X0B3) |
|
|
3e-63 |
247 |
36% |
|
- Product
- Putative cytochrome P450
- Gene
- ecm12
- Organism
- Streptomyces lasaliensis
|
1uniprot[Pubmed] 16799553 Total biosynthesis of antitumor nonribosomal peptides in Escherichia coli.(Nat. Chem. Biol.) [2006] |
|
19
|
B0L7G0_9ACTO (B0L7G0) |
|
|
4e-63 |
246 |
34% |
|
- Product
- SalD
- Gene
- salD
- Organism
- Salinispora tropica
|
1uniprot[Pubmed] 19590008 Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S-adenosyl-L-methionine.(Proc. Natl. Acad. Sci. U.S.A.) [2009] |
|
21
|
F1C7Q5_9ACTO (F1C7Q5) |
|
|
1e-61 |
241 |
33% |
|
- Product
- Cytochrome P450 hydroxylase
- Gene
- salD
- Organism
- Salinispora pacifica
|
1uniprot[Pubmed] 21154492 The discovery of salinosporamide K from the Marine Bacterium "Salinispora pacifica" by genome mining gives insight into pathway evolution.(Chembiochem) [2011] |
|
22
|
F2YRY7_9ACTO (F2YRY7) |
|
|
1e-60 |
238 |
34% |
|
- Product
- P450 monooxygenase
- Gene
- sky32
- Organism
- Streptomyces sp. Acta 2897
|
1uniprot[Pubmed] 21456593 Biosynthetic Gene Cluster of the Non-ribosomally Synthesized Cyclodepsipeptide Skyllamycin: Deciphering Unprecedented Ways of Unusual Hydroxylation Reactions.(J. Am. Chem. Soc.) [2011] |
|
25
|
Q333V7_9ACTO (Q333V7) |
|
|
7e-60 |
236 |
35% |
|
- Product
- Quinaldate 3-hydroxylase
- Gene
- tioI
- Organism
- Micromonospora sp. ML1
|
1uniprot Deciphering the biosynthesis pathway of the antitumor thiocoraline from a marine actinomycete and its expression in Streptomyces hosts.(Chembiochem) [2006] |
|
27
|
B1VL68_STRGG (B1VL68) |
|
|
2e-59 |
234 |
35% |
|
- Product
- Putative cytochrome P450
- Gene
- SGR_3267
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
28
|
F2RDK7_STRVP (F2RDK7) |
|
|
5e-59 |
233 |
34% |
|
- Product
- Putative cytochrome P450 hydroxylase
- Gene
- SVEN_6213
- Organism
- Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
|
1uniprot[Pubmed] 21463507 Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011] |
|
32
|
E2Q2J2_STRCL (E2Q2J2) |
|
|
4e-58 |
230 |
34% |
|
- Product
- Putative cytochrome P450
- Gene
- SCLAV_5636
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot[Pubmed] 20624727 The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
33
|
Q9F5J3_STRAT (Q9F5J3) |
|
|
1e-57 |
228 |
33% |
|
- Product
- SimI
- Gene
- simI
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 12115055 [Medline] 22109063 Cloning and analysis of the simocyclinone biosynthetic gene cluster of Streptomyces antibioticus Tu 6040.(Arch. Microbiol.) [2002] |
|
34
|
Q0S7N3_RHOSR (Q0S7N3) |
|
|
3e-57 |
227 |
35% |
|
- Product
- Cytochrome P450 CYP125
- Gene
- RHA1_ro04667
- Organism
- Rhodococcus sp. (strain RHA1)
|
1uniprot[Pubmed] 17030794 The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse.(Proc. Natl. Acad. Sci. U.S.A.) [2006] |
|
35
|
Q9AMH4_STRAT (Q9AMH4) |
|
|
4e-57 |
226 |
32% |
|
- Product
- Putative cytochrome P450 oxidase SimD1
- Gene
- simD1
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 11959542 [Medline] 21955989 Biosynthetic gene cluster of simocyclinone, a natural multihybrid antibiotic.(Antimicrob. Agents Chemother.) [2002] |
|
37
|
A9FBP8_SORC5 (A9FBP8) |
|
|
1e-56 |
225 |
34% |
|
- Product
- Cytochrome P450 CYP124E1
- Gene
- sce7867
- Organism
- Sorangium cellulosum (strain So ce56)
Polyangium cellulosum (strain So ce56)
|
1uniprot[Pubmed] 17965706 Complete genome sequence of the myxobacterium Sorangium cellulosum.(Nat. Biotechnol.) [2007] |
|
38
|
Q5PT49_STRTI (Q5PT49) |
|
|
2e-56 |
224 |
33% |
|
- Product
- Putative cytochrome P450
TrsB
- Gene
- trsB
- Organism
- Streptomyces triostinicus
|
1uniprot[Pubmed] 15569690 Functional cross-talk between fatty acid synthesis and nonribosomal peptide synthesis in quinoxaline antibiotic-producing streptomycetes.(J. Biol. Chem.) [2005] |
|
40
|
C9Z1X2_STRSW (C9Z1X2) |
|
|
5e-55 |
220 |
34% |
|
- Product
- P450-like protein
- Gene
- SCAB_9651
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
41
|
Q93H05_STRAW (Q93H05) |
|
|
6e-55 |
219 |
32% |
|
- Product
- Cytochrome P450
Putative cytochrome P450
- Gene
- cyp4
SAV838 SAV_838
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
42
|
C7PZI0_CATAD (C7PZI0) |
|
|
1e-54 |
218 |
31% |
|
- Product
- Cytochrome P450
- Gene
- Caci_2722
- Organism
- Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
|
1uniprot Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009] |
|
43
|
D2BFL7_STRRD (D2BFL7) |
|
|
2e-54 |
218 |
35% |
|
- Product
- Cytochrome P450 family protein
- Gene
- Sros_7496
- Organism
- Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
|
1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010] |
|
46
|
Q7N7D1_PHOLL (Q7N7D1) |
|
|
6e-54 |
216 |
31% |
|
- Product
- Similar to Sim-nI
- Gene
- plu1219
- Organism
- Photorhabdus luminescens subsp. laumondii (strain TT01)
|
1uniprot[Pubmed] 14528314 [Medline] 22957627 The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens.(Nat. Biotechnol.) [2003] |
|
48
|
D1ACD1_THECD (D1ACD1) |
|
|
7e-54 |
216 |
34% |
|
- Product
- Cytochrome P450
- Gene
- Tcur_3656
- Organism
- Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
|
1uniprot Complete genome sequence of Thermomonospora curvata type strain (B9).(Stand. Genomic Sci.) [2011] |
|
49
|
Q73WS6_MYCPA (Q73WS6) |
|
|
7e-54 |
216 |
35% |
|
- Product
- Putative uncharacterized protein
- Gene
- MAP_2584
- Organism
- Mycobacterium paratuberculosis
|
1uniprot[Pubmed] 16116077 The complete genome sequence of Mycobacterium avium subspecies paratuberculosis.(Proc. Natl. Acad. Sci. U.S.A.) [2005] |
|
51
|
D1ACZ6_THECD (D1ACZ6) |
|
|
8e-54 |
216 |
33% |
|
- Product
- Cytochrome P450
- Gene
- Tcur_3772
- Organism
- Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
|
1uniprot Complete genome sequence of Thermomonospora curvata type strain (B9).(Stand. Genomic Sci.) [2011] |
|
55
|
C7Q911_CATAD (C7Q911) |
|
|
2e-53 |
214 |
31% |
|
- Product
- Cytochrome P450
- Gene
- Caci_3425
- Organism
- Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
|
1uniprot Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009] |
|
56
|
Q0SE76_RHOSR (Q0SE76) |
|
|
6e-53 |
213 |
33% |
|
- Product
- Cytochrome P450 CYP125
- Gene
- RHA1_ro02355
- Organism
- Rhodococcus sp. (strain RHA1)
|
1uniprot[Pubmed] 17030794 The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse.(Proc. Natl. Acad. Sci. U.S.A.) [2006] |
|
57
|
D7C410_STRBB (D7C410) |
|
|
7e-53 |
213 |
33% |
|
- Product
- Putative cytochrome P450
- Gene
- cyp46
SBI_09258
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
58
|
Q9F8V1_9ACTO (Q9F8V1) |
|
|
8e-53 |
212 |
31% |
|
- Product
- Cytochrome P-450
- Gene
- couI
- Organism
- Streptomyces rishiriensis
|
1uniprot[Pubmed] 11036020 [Medline] 20493109 Identification of the coumermycin A(1) biosynthetic gene cluster of Streptomyces rishiriensis DSM 40489.(Antimicrob. Agents Chemother.) [2000] |
|
59
|
Q2PC49_STRAH (Q2PC49) |
|
|
1e-52 |
211 |
32% |
|
- Product
- Putative cytochrome P450
- Gene
- rubC2
- Organism
- Streptomyces achromogenes subsp. rubradiris
|
1uniprot[Pubmed] 9387157 [Medline] 98048398 Identification of a gene cluster of biosynthetic genes of rubradirin substructures in S. achromogenes var. rubradiris NRRL3061.(Mol. Cells) [1997] | 2uniprot[Pubmed] 12889805 [Medline] 22771458 Functional identification of rub52 gene involved in the biosynthesis of rubradirin.(Biotechnol. Lett.) [2003] | [pubmed all]
|
62
|
Q8GHC6_9ACTO (Q8GHC6) |
|
|
9e-52 |
209 |
30% |
|
- Product
- Cytochrome P450
- Gene
- cloI
- Organism
- Streptomyces roseochromogenes subsp. oscitans
|
1uniprot[Pubmed] 12480894 [Medline] 22368916 Molecular cloning and sequence analysis of the clorobiocin biosynthetic gene cluster: new insights into the biosynthesis of aminocoumarin antibiotics.(Microbiology) [2002] |
|
63
|
F4F5Y2_VERMA (F4F5Y2) |
|
|
2e-51 |
208 |
33% |
|
- Product
- Cytochrome P450
- Gene
- VAB18032_22205
- Organism
- Verrucosispora maris (strain AB-18-032)
|
1uniprot[Pubmed] 21551311 Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011] |
|
67
|
A4FJG1_SACEN (A4FJG1) |
|
|
5e-51 |
206 |
32% |
|
- Product
- Cytochrome P450 monooxygenase
- Gene
- SACE_4920
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
70
|
Q9L9F9_STRSH (Q9L9F9) |
|
|
9e-51 |
206 |
30% |
|
- Product
- NovI
- Gene
- novI
- Organism
- Streptomyces spheroides
Streptomyces caeruleus
|
1uniprot[Pubmed] 10770754 [Medline] 20233587 Identification of the novobiocin biosynthetic gene cluster of Streptomyces spheroides NCIB 11891.(Antimicrob. Agents Chemother.) [2000] |
|
74
|
A4FFH4_SACEN (A4FFH4) |
|
|
3e-50 |
204 |
34% |
|
- Product
- Cytochrome P450 CYP125
- Gene
- SACE_3525
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
75
|
D7CHX6_STRBB (D7CHX6) |
|
|
5e-50 |
203 |
33% |
|
- Product
- Cytochrome P450
- Gene
- cyp32
SBI_06056
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
76
|
Q5LVD8_SILPO (Q5LVD8) |
|
|
7e-50 |
202 |
32% |
|
- Product
- Cytochrome P450 family protein
- Gene
- SPO0764
- Organism
- Silicibacter pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)
|
1uniprot[Pubmed] 15602564 Genome sequence of Silicibacter pomeroyi reveals adaptations to the marine environment.(Nature) [2004] |
|
89
|
D1A4X2_THECD (D1A4X2) |
|
|
6e-49 |
199 |
32% |
|
- Product
- Cytochrome P450
- Gene
- Tcur_2583
- Organism
- Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
|
1uniprot Complete genome sequence of Thermomonospora curvata type strain (B9).(Stand. Genomic Sci.) [2011] |
|