BLAST table : A4793_00220

DB	UniProtKB

	accession	Evalue	Score	Ident.	link	product	gene	organism	ec
1	Q8KLK5_STRTO (Q8KLK5)	0.0	793	100%	UniProt GenBank	DpgA		Streptomyces toyocaensis
2	E2D2E5_9BACT (E2D2E5)	1e-178	628	80%	UniProt GenBank	Dihydroxyphenylglycine synthase subunit A		uncultured soil bacterium
3	Q939X3_9PSEU (Q939X3)	1e-160	567	74%	UniProt GenBank	Dihydroxyphenylacetic acid synthase	dpgA	Amycolatopsis balhimycina
4	B7T1A9_9BACT (B7T1A9)	1e-159	567	73%	UniProt GenBank	Veg37	veg37	uncultured soil bacterium
5	O52795_AMYOR (O52795)	1e-159	565	74%	UniProt GenBank	PCZA361.6		Amycolatopsis orientalis Nocardia orientalis
6	Q7WZ60_9ACTO (Q7WZ60)	1e-158	561	72%	UniProt GenBank	Putative DpgA protein	dbv31	Nonomuraea sp. ATCC 39727
7	Q2JA67_FRASC (Q2JA67)	1e-157	560	76%	UniProt GenBank	Chalcone and stilbene synthases-like	Francci3_2458	Frankia sp. (strain CcI3)
8	F8STZ6_AMYOR (F8STZ6)	1e-157	558	78%	UniProt GenBank	Dihydrophenylactic synthase	vcm23	Amycolatopsis orientalis Nocardia orientalis
9	Q6ZZH6_ACTTI (Q6ZZH6)	1e-156	554	73%	UniProt GenBank	DpgA protein	tcp30	Actinoplanes teichomyceticus
10	E9L1N9_9ZZZZ (E9L1N9)	1e-154	548	77%	UniProt GenBank	Putative uncharacterized protein	CA878-40	uncultured organism CA878
11	E9L1I8_9ZZZZ (E9L1I8)	1e-153	545	78%	UniProt GenBank	Putative uncharacterized protein	CA37-44	uncultured organism CA37
12	E9L1T9_9ZZZZ (E9L1T9)	1e-151	540	75%	UniProt GenBank	Putative uncharacterized protein	CA915-47	uncultured organism CA915
13	D9UHH5_9ACTO (D9UHH5)	1e-144	514	70%	UniProt GenBank	Dihydroxyphenylacetic acid synthase	SSLG_05411	Streptomyces sp. SPB78
14	F3ZDK7_9ACTO (F3ZDK7)	1e-143	514	74%	UniProt GenBank	Putative dihydroxyphenylacetic acid synthase	STTU_1160	Streptomyces sp. Tu6071
15	C0Z471_STRVN (C0Z471)	1e-142	508	70%	UniProt GenBank	Type III polyketide synthase	ken2	Streptomyces violaceoruber
16	D7B4X8_NOCDD (D7B4X8)	1e-141	505	70%	UniProt GenBank	Chalcone and stilbene synthase domain protein	Ndas_1740	Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) Actinomadura dassonvillei
17	F2R788_STRVP (F2R788)	1e-133	478	67%	UniProt GenBank	Chalcone synthase	SVEN_0493	Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)	2.3.1.74 niceE keggE
18	F3NRX4_9ACTO (F3NRX4)	1e-130	470	65%	UniProt GenBank	Chalcone and stilbene synthase domain protein, type-III PKS	SGM_5888	Streptomyces griseoaurantiacus M045
19	D6A5M6_9ACTO (D6A5M6)	1e-127	459	64%	UniProt GenBank	Dihydroxyphenylacetic acid synthase	SSFG_06974	Streptomyces ghanaensis ATCC 14672
20	D2PSP1_KRIFD (D2PSP1)	1e-122	443	63%	UniProt GenBank	3-Oxoacyl-(Acyl-carrier-protein (ACP)) synthase III domain protein	Kfla_4132	Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399)
21	D2UD60_XANAP (D2UD60)	1e-117	426	59%	UniProt GenBank	Putative acyltransferase protein	XALc_1059	Xanthomonas albilineans (strain GPE PC73 / CFBP 7063)	2.3.1.- niceE keggE
22	C6N494_9GAMM (C6N494)	3e-83	313	44%	UniProt GenBank	Putative DpgA	LDG_2449	Legionella drancourtii LLAP12
23	Q2IMY3_ANADE (Q2IMY3)	1e-45	188	35%	UniProt GenBank	Chalcone/stilbene synthase-like protein	Adeh_0387	Anaeromyxobacter dehalogenans (strain 2CP-C)
24	B8JAW2_ANAD2 (B8JAW2)	2e-44	184	35%	UniProt GenBank	Chalcone and stilbene synthase domain protein	A2cp1_0416	Anaeromyxobacter dehalogenans (strain 2CP-1 / ATCC BAA-258)
25	B4UB09_ANASK (B4UB09)	9e-44	182	35%	UniProt GenBank	3-Oxoacyl-(Acyl-carrier-protein (ACP)) synthase III domain protein	AnaeK_0415	Anaeromyxobacter sp. (strain K)
26	A3TNL8_9MICO (A3TNL8)	1e-41	175	35%	UniProt GenBank	Possible chalcone synthase	JNB_14218	Janibacter sp. HTCC2649
27	F5SK97_9BACL (F5SK97)	2e-41	174	34%	UniProt GenBank	Chalcone/stilbene synthase	bcsA HMPREF9374_3529	Desmospora sp. 8437	2.3.1.74 niceE keggE
28	C1F687_ACIC5 (C1F687)	1e-39	169	32%	UniProt GenBank	Chalcone/stilbene synthase family protein	ACP_3317	Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670)
29	D5MLA6_9BACT (D5MLA6)	2e-39	168	31%	UniProt GenBank	Putative Chalcone and stilbene synthase domain protein	DAMO_0702	NC10 bacterium 'Dutch sediment'
30	A3XIK8_LEEBM (A3XIK8)	4e-39	167	30%	UniProt GenBank	Naringenin-chalcone synthase	MED217_06242	Leeuwenhoekiella blandensis (strain CECT 7118 / CCUG 51940 / MED217) Flavobacterium sp. (strain MED217)
31	D5P3E6_9MYCO (D5P3E6)	7e-38	162	33%	UniProt GenBank	Possible Naringenin-chalcone synthase	HMPREF0591_0690	Mycobacterium parascrofulaceum ATCC BAA-614	2.3.1.74 niceE keggE
32	C8XB93_NAKMY (C8XB93)	2e-37	160	35%	UniProt GenBank	Chalcone and stilbene synthase domain protein	Namu_5115	Nakamurella multipartita (strain ATCC 700099 / DSM 44233 / JCM 9543 / Y-104) Microsphaera multipartita
33	C7PPQ6_CHIPD (C7PPQ6)	4e-36	157	31%	UniProt GenBank	Chalcone and stilbene synthase domain protein	Cpin_5033	Chitinophaga pinensis (strain ATCC 43595 / DSM 2588 / NCIB 11800 / UQM 2034)
34	A7HI17_ANADF (A7HI17)	1e-35	155	32%	UniProt GenBank	3-Oxoacyl-(Acyl-carrier-protein (ACP)) synthase III domain protein	Anae109_4185	Anaeromyxobacter sp. (strain Fw109-5)
35	E6PWQ2_9ZZZZ (E6PWQ2)	2e-35	155	31%	UniProt GenBank	Chalcone and stilbene synthases-like	CARN3_0271	mine drainage metagenome
36	D2QMD5_SPILD (D2QMD5)	3e-35	154	29%	UniProt GenBank	Chalcone and stilbene synthase domain protein	Slin_3187	Spirosoma linguale (strain ATCC 33905 / DSM 74 / LMG 10896)
37	B2IIY3_BEII9 (B2IIY3)	2e-34	151	31%	UniProt GenBank	3-Oxoacyl-(Acyl-carrier-protein (ACP)) synthase III domain protein	Bind_2602	Beijerinckia indica subsp. indica (strain ATCC 9039 / DSM 1715 / NCIB 8712)
38	Q1ILZ4_ACIBL (Q1ILZ4)	4e-34	150	32%	UniProt GenBank	Chalcone and stilbene synthases-like protein	Acid345_3105	Acidobacteria bacterium (strain Ellin345)
39	E6XBH5_CELAD (E6XBH5)	8e-34	149	29%	UniProt GenBank	Naringenin-chalcone synthase	Celal_3841	Cellulophaga algicola (strain DSM 14237 / IC166 / ACAM 630)	2.3.1.74 niceE keggE
40	Q09BD6_STIAD (Q09BD6)	9e-34	149	33%	UniProt GenBank	Chalcone/stilbene synthase family protein Naringenin-chalcone synthase	STAUR_1255 STIAU_8629	Stigmatella aurantiaca (strain DW4/3-1)
41	B1VQK0_STRGG (B1VQK0)	1e-33	149	31%	UniProt GenBank	Type-III PKS	srsA SGR_472	Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
42	F7TWM5_9BACL (F7TWM5)	1e-33	149	30%	UniProt GenBank	Putative chalcone synthase	BRLA_c23490	Brevibacillus laterosporus LMG 15441
43	D5E1D8_BACMQ (D5E1D8)	2e-33	148	28%	UniProt GenBank	Naringenin-chalcone synthase	BMQ_1456	Bacillus megaterium (strain ATCC 12872 / QMB1551)	2.3.1.74 niceE keggE
44	Q26DN5_FLABB (Q26DN5)	3e-33	147	29%	UniProt GenBank	Naringenin-chalcone synthase	BBFL7_00289	Flavobacteria bacterium (strain BBFL7)	2.3.1.74 niceE keggE
45	A0M1T8_GRAFK (A0M1T8)	4e-33	147	28%	UniProt GenBank	Naringenin-chalcone synthase	bcsA GFO_1610	Gramella forsetii (strain KT0803)	2.3.1.74 niceE keggE
46	D5DD68_BACMD (D5DD68)	4e-33	147	28%	UniProt GenBank	Naringenin-chalcone synthase	BMD_1438	Bacillus megaterium (strain DSM 319)	2.3.1.74 niceE keggE
47	D5H907_SALRM (D5H907)	8e-33	145	33%	UniProt GenBank	Naringenin-chalcone synthase	bcsA SRM_01591	Salinibacter ruber (strain M8)	2.3.1.74 niceE keggE
48	E8WUD7_GEOS8 (E8WUD7)	1e-32	145	32%	UniProt GenBank	Chalcone and stilbene synthase domain protein	GM18_0879	Geobacter sp. (strain M18)
49	Q2S2R2_SALRD (Q2S2R2)	1e-32	145	33%	UniProt GenBank	Chalcone synthase, putative	SRU_1395	Salinibacter ruber (strain DSM 13855 / M31)	2.3.1.- niceE keggE
50	E8WZV9_ACISM (E8WZV9)	1e-32	145	30%	UniProt GenBank	Chalcone and stilbene synthase domain protein	AciX9_0700	Acidobacterium sp. (strain MP5ACTX9)
51	F8CAB4_MYXFU (F8CAB4)	1e-32	145	30%	UniProt GenBank	Chalcone/stilbene synthase family protein	LILAB_13320	Myxococcus fulvus
52	C8XT88_9BACT (C8XT88)	1e-32	145	31%	UniProt GenBank	Rmp57 type III polyketide synthase		uncultured bacterium RM57
53	D3FC93_CONWI (D3FC93)	1e-32	145	29%	UniProt GenBank	Chalcone and stilbene synthase domain protein	Cwoe_4977	Conexibacter woesei (strain DSM 14684 / JCM 11494 / NBRC 100937 / ID131577)
54	B5ZR65_RHILW (B5ZR65)	2e-32	145	30%	UniProt GenBank	3-Oxoacyl-(Acyl-carrier-protein (ACP)) synthase III domain protein	Rleg2_0398	Rhizobium leguminosarum bv. trifolii (strain WSM2304)
55	Q2B424_9BACI (Q2B424)	2e-32	145	29%	UniProt GenBank	Naringenin-chalcone synthase	B14911_06918	Bacillus sp. NRRL B-14911
56	E3J5E9_FRASU (E3J5E9)	2e-32	145	31%	UniProt GenBank	Chalcone and stilbene synthase domain protein	FraEuI1c_3887	Frankia sp. (strain EuI1c)
57	A3U9Q4_CROAH (A3U9Q4)	2e-32	144	28%	UniProt GenBank	Naringenin-chalcone synthase	CA2559_10908	Croceibacter atlanticus (strain ATCC BAA-628 / HTCC2559 / KCTC 12090)
58	B7GKS5_ANOFW (B7GKS5)	3e-32	144	29%	UniProt GenBank	Naringenin-chalcone synthase	bcsA Aflv_1363	Anoxybacillus flavithermus (strain DSM 21510 / WK1)
59	A6ED58_9SPHI (A6ED58)	4e-32	144	28%	UniProt GenBank	Chalcone/stilbene synthase family protein	PBAL39_25200	Pedobacter sp. BAL39
60	Q1CXW7_MYXXD (Q1CXW7)	7e-32	143	31%	UniProt GenBank	Chalcone/stilbene synthase family protein	MXAN_6639	Myxococcus xanthus (strain DK 1622)
61	A4BX89_9FLAO (A4BX89)	8e-32	142	27%	UniProt GenBank	Naringenin-chalcone synthase	PI23P_03762	Polaribacter irgensii 23-P
62	PKS1_DICDI (Q55E72)	8e-32	142	29%	UniProt GenBank	Probable polyketide synthase 1 Polyketide synthase stlA Chalcone synthase stlA Steely1	stlA pks1 DDB_G0269364	Dictyostelium discoideum Slime mold	2.3.1.- niceE keggE 2.3.1.74 niceE keggE
63	A2TPD4_9FLAO (A2TPD4)	9e-32	142	26%	UniProt GenBank	3-oxoacyl-[acyl-carrier-protein (ACP)] synthase III	MED134_04714	Dokdonia donghaensis MED134
64	A2TYE6_9FLAO (A2TYE6)	2e-31	141	25%	UniProt GenBank	3-oxoacyl-[acyl-carrier-protein (ACP)] synthase III	MED152_08615	Polaribacter sp. MED152
65	F4Q2Z0_DICFS (F4Q2Z0)	2e-31	141	28%	UniProt GenBank	Putative polyketide synthase	stlA DFA_08550	Dictyostelium fasciculatum (strain SH3) Slime mold
66	E6SG44_INTC7 (E6SG44)	3e-31	140	31%	UniProt GenBank	Chalcone and stilbene synthase domain protein	Intca_3524	Intrasporangium calvum (strain ATCC 23552 / DSM 43043 / JCM 3097 / NBRC 12989 / 7 KIP)
67	B3PQG4_RHIE6 (B3PQG4)	3e-31	140	29%	UniProt GenBank	Probable chalcone synthase protein	RHECIAT_CH0000823	Rhizobium etli (strain CIAT 652)	2.3.1.74 niceE keggE
68	C6XUK5_PEDHD (C6XUK5)	3e-31	140	27%	UniProt GenBank	Chalcone and stilbene synthase domain protein	Phep_1642	Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / NCIB 9290)
69	A3PZ25_MYCSJ (A3PZ25)	3e-31	140	30%	UniProt GenBank	Chalcone and stilbene synthases domain protein	Mjls_2367	Mycobacterium sp. (strain JLS)
70	A0QQM4_MYCS2 (A0QQM4)	4e-31	140	32%	UniProt GenBank	Possible chalcone synthase Pks10	MSMEG_0808	Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
71	A5FDA2_FLAJ1 (A5FDA2)	4e-31	140	26%	UniProt GenBank	Chalcone/stilbene polyketide synthase family protein	Fjoh_3808	Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / UW101) Cytophaga johnsonae
72	Q2KC78_RHIEC (Q2KC78)	4e-31	140	29%	UniProt GenBank	Probable chalcone synthase protein	RHE_CH00744	Rhizobium etli (strain CFN 42 / ATCC 51251)	2.3.1.74 niceE keggE
73	Q1BD61_MYCSS (Q1BD61)	9e-31	139	31%	UniProt GenBank	Chalcone and stilbene synthases-like protein	Mmcs_1059	Mycobacterium sp. (strain MCS)
74	A1UBT1_MYCSK (A1UBT1)	9e-31	139	31%	UniProt GenBank	Chalcone and stilbene synthases domain protein	Mkms_1075	Mycobacterium sp. (strain KMS)
75	A3PVG6_MYCSJ (A3PVG6)	1e-30	139	32%	UniProt GenBank	Chalcone and stilbene synthases domain protein	Mjls_1086	Mycobacterium sp. (strain JLS)
76	F7NDK8_9FIRM (F7NDK8)	1e-30	138	28%	UniProt GenBank	Naringenin-chalcone synthase	ALO_00575	Acetonema longum DSM 6540
77	C6DS06_MYCTK (C6DS06)	1e-30	138	30%	UniProt GenBank	Chalcone synthase pks11	TBMG_02328	Mycobacterium tuberculosis (strain KZN 1435 / MDR)
78	C1ANT8_MYCBT (C1ANT8)	1e-30	138	30%	UniProt GenBank	Putative chalcone synthase	pks11 JTY_1679	Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019)	2.3.1.74 niceE keggE
79	A5WMY7_MYCTF (A5WMY7)	1e-30	138	30%	UniProt GenBank	Chalcone synthase pks11	TBFG_11683	Mycobacterium tuberculosis (strain F11)
80	A5U322_MYCTA (A5U322)	1e-30	138	30%	UniProt GenBank	Putative chalcone synthase Pks11	pks11 MRA_1676	Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
81	A1KJ82_MYCBP (A1KJ82)	1e-30	138	30%	UniProt GenBank	Possible chalcone synthase pks11	pks11 BCG_1704	Mycobacterium bovis (strain BCG / Pasteur 1173P2)	2.3.1.74 niceE keggE
82	F8M8Q1_9MYCO (F8M8Q1)	1e-30	138	30%	UniProt GenBank	Putative chalcone synthase pks11	pks11 MAF_16820	Mycobacterium africanum GM041182	2.3.1.74 niceE keggE
83	F2V862_MYCTU (F2V862)	1e-30	138	30%	UniProt GenBank	Chalcone synthase pks11	TBPG_01147	Mycobacterium tuberculosis W-148
84	F2GKM4_MYCTU (F2GKM4)	1e-30	138	30%	UniProt GenBank	Chalcone synthase pks11	TBSG_02340	Mycobacterium tuberculosis KZN 4207
85	E9ZJ99_MYCTU (E9ZJ99)	1e-30	138	30%	UniProt GenBank	Chalcone synthase pks11	TMMG_00916	Mycobacterium tuberculosis CDC1551A
86	E2WHH3_MYCTU (E2WHH3)	1e-30	138	30%	UniProt GenBank	Chalcone synthase pks11	TMLG_00648	Mycobacterium tuberculosis SUMu012
87	E2W5I8_MYCTU (E2W5I8)	1e-30	138	30%	UniProt GenBank	Chalcone synthase pks11	TMKG_02172	Mycobacterium tuberculosis SUMu011
88	E2VU94_MYCTU (E2VU94)	1e-30	138	30%	UniProt GenBank	Chalcone synthase pks11	TMJG_03098	Mycobacterium tuberculosis SUMu010
89	E2VI09_MYCTU (E2VI09)	1e-30	138	30%	UniProt GenBank	Chalcone synthase pks11	TMIG_01920	Mycobacterium tuberculosis SUMu009
90	E2V8Q2_MYCTU (E2V8Q2)	1e-30	138	30%	UniProt GenBank	Chalcone synthase pks11	TMHG_00848	Mycobacterium tuberculosis SUMu008
91	E2UYI4_MYCTU (E2UYI4)	1e-30	138	30%	UniProt GenBank	Chalcone synthase pks11	TMGG_00212	Mycobacterium tuberculosis SUMu007
92	E2UL90_MYCTU (E2UL90)	1e-30	138	30%	UniProt GenBank	Chalcone synthase pks11	TMFG_00751	Mycobacterium tuberculosis SUMu006
93	E2U9R1_MYCTU (E2U9R1)	1e-30	138	30%	UniProt GenBank	Chalcone synthase pks11	TMEG_01565	Mycobacterium tuberculosis SUMu005
94	E2TYC7_MYCTU (E2TYC7)	1e-30	138	30%	UniProt GenBank	Chalcone synthase pks11	TMDG_03384	Mycobacterium tuberculosis SUMu004
95	E2T9F0_MYCTU (E2T9F0)	1e-30	138	30%	UniProt GenBank	Chalcone synthase pks11	TMBG_00211	Mycobacterium tuberculosis SUMu002
96	E1H9G4_MYCTU (E1H9G4)	1e-30	138	30%	UniProt GenBank	Chalcone synthase pks11	TMAG_01499	Mycobacterium tuberculosis SUMu001
97	D7ERA1_MYCTU (D7ERA1)	1e-30	138	30%	UniProt GenBank	Chalcone synthase pks11	TBAG_00584	Mycobacterium tuberculosis 94_M4241A
98	D5ZHF7_MYCTU (D5ZHF7)	1e-30	138	30%	UniProt GenBank	Chalcone synthase pks11	TBJG_00079	Mycobacterium tuberculosis T17
99	D5Z4E9_MYCTU (D5Z4E9)	1e-30	138	30%	UniProt GenBank	Chalcone synthase pks11	TBIG_01055	Mycobacterium tuberculosis GM 1503
100	D5YT81_MYCTU (D5YT81)	1e-30	138	30%	UniProt GenBank	Chalcone synthase pks11	TBBG_01348	Mycobacterium tuberculosis 02_1987

accession

alignment

Evalue

Score

Ident.

link

information

pubmed

Q8KLK5_STRTO
(Q8KLK5)

0.0

793

100%

Product: DpgA
Gene
Organism: Streptomyces toyocaensis

[pubmed all]
1uniprot[Pubmed] 9177243 [Medline] 97322398 D-Ala-D-Ala ligases from glycopeptide antibiotic-producing organisms are highly homologous to the enterococcal vancomycin-resistance ligases VanA and VanB.(Proc. Natl. Acad. Sci. U.S.A.) [1997]
2uniprot[Pubmed] 12060705 [Medline] 22080153 Assembling the glycopeptide antibiotic scaffold: the biosynthesis of A47934 from Streptomyces toyocaensis NRRL15009.(Proc. Natl. Acad. Sci. U.S.A.) [2002]

E2D2E5_9BACT
(E2D2E5)

1e-178

628

80%

Product: Dihydroxyphenylglycine synthase subunit A
Gene
Organism: uncultured soil bacterium

1uniprot[Pubmed] 20577994
Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR.(Biopolymers) [2010]

Q939X3_9PSEU
(Q939X3)

1e-160

567

74%

Product: Dihydroxyphenylacetic acid synthase
Gene: dpgA
Organism: Amycolatopsis balhimycina

[pubmed all]
1uniprot[Pubmed] 10390204 [Medline] 99318579 Identification and analysis of the balhimycin biosynthetic gene cluster and its use for manipulating glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908.(Antimicrob. Agents Chemother.) [1999]
2uniprot[Pubmed] 11932455 [Medline] 21930292 Nonribosomal biosynthesis of vancomycin-type antibiotics: a heptapeptide backbone and eight peptide synthetase modules.(Microbiology) [2002]
3uniprot[Pubmed] 11495926 [Medline] 21486455 A polyketide synthase in glycopeptide biosynthesis: the biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine.(J. Biol. Chem.) [2001]
4uniprot[Pubmed] 12404385 The biosynthesis of vancomycin-type glycopeptide antibiotics - the order of cyclization steps.(Angew. Chem. Int. Ed. Engl.) [2001]
5uniprot[Pubmed] 11880037 [Medline] 21869276 Glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908: function of a halogenase and a haloperoxidase/perhydrolase.(Chem. Biol.) [2002]
6uniprot Precursor-directed biosynthesis for the generation of novel glycopetides.(Ernst Schering Res. Found. Workshop) [2005]

B7T1A9_9BACT
(B7T1A9)

1e-159

567

73%

Product: Veg37
Gene: veg37
Organism: uncultured soil bacterium

1uniprot[Pubmed] 18987322
Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary.(Proc. Natl. Acad. Sci. U.S.A.) [2008]

O52795_AMYOR
(O52795)

1e-159

565

74%

Product: PCZA361.6
Gene
Organism: Amycolatopsis orientalis
Nocardia orientalis

1uniprot[Pubmed] 9545426 [Medline] 98212597
Sequencing and analysis of genes involved in the biosynthesis of a vancomycin group antibiotic.(Chem. Biol.) [1998]

Q7WZ60_9ACTO
(Q7WZ60)

1e-158

561

72%

Product: Putative DpgA protein
Gene: dbv31
Organism: Nonomuraea sp. ATCC 39727

1uniprot[Pubmed] 12837387 [Medline] 22721464
The gene cluster for the biosynthesis of the glycopeptide antibiotic A40926 by nonomuraea species.(Chem. Biol.) [2003]

Q2JA67_FRASC
(Q2JA67)

1e-157

560

76%

Product: Chalcone and stilbene synthases-like
Gene: Francci3_2458
Organism: Frankia sp. (strain CcI3)

1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]

Q6ZZH6_ACTTI
(Q6ZZH6)

1e-156

554

73%

Product: DpgA protein
Gene: tcp30
Organism: Actinoplanes teichomyceticus

[pubmed all]
1uniprot[Pubmed] 15113000 Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase.(Chem. Biol.) [2004]
2uniprot[Pubmed] 14702401 Organization of the teicoplanin gene cluster in Actinoplanes teichomyceticus.(Microbiology) [2004]

E9L1N9_9ZZZZ
(E9L1N9)

1e-154

548

77%

Product: Putative uncharacterized protein
Gene: CA878-40
Organism: uncultured organism CA878

1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]

E9L1I8_9ZZZZ
(E9L1I8)

1e-153

545

78%

Product: Putative uncharacterized protein
Gene: CA37-44
Organism: uncultured organism CA37

1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]

E9L1T9_9ZZZZ
(E9L1T9)

1e-151

540

75%

Product: Putative uncharacterized protein
Gene: CA915-47
Organism: uncultured organism CA915

1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]

D7B4X8_NOCDD
(D7B4X8)

1e-141

505

70%

Product: Chalcone and stilbene synthase domain protein
Gene: Ndas_1740
Organism: Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei

1uniprot
Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010]

F2R788_STRVP
(F2R788)

1e-133

478

67%

Product: Chalcone synthase
Gene: SVEN_0493
Organism: Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)

1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]

F3NRX4_9ACTO
(F3NRX4)

1e-130

470

65%

Product: Chalcone and stilbene synthase domain protein, type-III PKS
Gene: SGM_5888
Organism: Streptomyces griseoaurantiacus M045

1uniprot[Pubmed] 21551298
Draft Genome Sequence of the Marine Bacterium Streptomyces griseoaurantiacus M045, Which Produces Novel Manumycin-Type Antibiotics with a pABA Core Component.(J. Bacteriol.) [2011]

D2UD60_XANAP
(D2UD60)

1e-117

426

59%

Product: Putative acyltransferase protein
Gene: XALc_1059
Organism: Xanthomonas albilineans (strain GPE PC73 / CFBP 7063)

1uniprot
The complete genome sequence of Xanthomonas albilineans provides new insights into the reductive genome evolution of the xylem-limited Xanthomonadaceae.(BMC Genomics) [2009]

A3TNL8_9MICO
(A3TNL8)

1e-41

175

35%

Product: Possible chalcone synthase
Gene: JNB_14218
Organism: Janibacter sp. HTCC2649

1uniprot[Pubmed] 21075932
Genome sequence of the Marine Janibacter Sp. Strain HTCC2649.(J. Bacteriol.) [2011]

C1F687_ACIC5
(C1F687)

1e-39

169

32%

Product: Chalcone/stilbene synthase family protein
Gene: ACP_3317
Organism: Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670)

1uniprot[Pubmed] 19201974
Three genomes from the phylum Acidobacteria provide insight into the lifestyles of these microorganisms in soils.(Appl. Environ. Microbiol.) [2009]

D5MLA6_9BACT
(D5MLA6)

2e-39

168

31%

Product: Putative Chalcone and stilbene synthase domain protein
Gene: DAMO_0702
Organism: NC10 bacterium 'Dutch sediment'

1uniprot
Nitrite-driven anaerobic methane oxidation by oxygenic bacteria.(Nature) [2010]

Q1ILZ4_ACIBL
(Q1ILZ4)

4e-34

150

32%

Product: Chalcone and stilbene synthases-like protein
Gene: Acid345_3105
Organism: Acidobacteria bacterium (strain Ellin345)

1uniprot[Pubmed] 19201974
Three genomes from the phylum Acidobacteria provide insight into the lifestyles of these microorganisms in soils.(Appl. Environ. Microbiol.) [2009]

E6XBH5_CELAD
(E6XBH5)

8e-34

149

29%

Product: Naringenin-chalcone synthase
Gene: Celal_3841
Organism: Cellulophaga algicola (strain DSM 14237 / IC166 / ACAM 630)

1uniprot
Complete genome sequence of Cellulophaga algicola type strain (IC166).(Stand. Genomic Sci.) [2010]

B1VQK0_STRGG
(B1VQK0)

1e-33

149

31%

Product: Type-III PKS
Gene: srsA
SGR_472
Organism: Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)

1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]

A0M1T8_GRAFK
(A0M1T8)

4e-33

147

28%

Product: Naringenin-chalcone synthase
Gene: bcsA
GFO_1610
Organism: Gramella forsetii (strain KT0803)

1uniprot[Pubmed] 17107561
Whole genome analysis of the marine Bacteroidetes'Gramella forsetii' reveals adaptations to degradation of polymeric organic matter.(Environ. Microbiol.) [2006]

Q2S2R2_SALRD
(Q2S2R2)

1e-32

145

33%

Product: Chalcone synthase, putative
Gene: SRU_1395
Organism: Salinibacter ruber (strain DSM 13855 / M31)

1uniprot[Pubmed] 16330755
The genome of Salinibacter ruber: convergence and gene exchange among hyperhalophilic bacteria and archaea.(Proc. Natl. Acad. Sci. U.S.A.) [2005]

C8XT88_9BACT
(C8XT88)

1e-32

145

31%

Product: Rmp57 type III polyketide synthase
Gene
Organism: uncultured bacterium RM57

1uniprot[Pubmed] 19146479
Natural products from environmental DNA hosted in Ralstonia metallidurans.(ACS Chem. Biol.) [2009]

A3U9Q4_CROAH
(A3U9Q4)

2e-32

144

28%

Product: Naringenin-chalcone synthase
Gene: CA2559_10908
Organism: Croceibacter atlanticus (strain ATCC BAA-628 / HTCC2559 / KCTC 12090)

1uniprot[Pubmed] 20639333
The complete genome sequence of Croceibacter atlanticus HTCC2559T.(J. Bacteriol.) [2010]

B7GKS5_ANOFW
(B7GKS5)

3e-32

144

29%

Product: Naringenin-chalcone synthase
Gene: bcsA
Aflv_1363
Organism: Anoxybacillus flavithermus (strain DSM 21510 / WK1)

1uniprot[Pubmed] 19014707
Encapsulated in silica: genome, proteome and physiology of the thermophilic bacterium Anoxybacillus flavithermus WK1.(Genome Biol.) [2008]

Q1CXW7_MYXXD
(Q1CXW7)

7e-32

143

31%

Product: Chalcone/stilbene synthase family protein
Gene: MXAN_6639
Organism: Myxococcus xanthus (strain DK 1622)

1uniprot[Pubmed] 17015832
Evolution of sensory complexity recorded in a myxobacterial genome.(Proc. Natl. Acad. Sci. U.S.A.) [2006]

PKS1_DICDI
(Q55E72)

8e-32

142

29%

Product: Probable polyketide synthase 1
Polyketide synthase stlA
Chalcone synthase stlA
Steely1
Gene: stlA
pks1
DDB_G0269364
Organism: Dictyostelium discoideum
Slime mold

[pubmed all]
1uniprot[Pubmed] 15875012 The genome of the social amoeba Dictyostelium discoideum.(Nature) [2005]
2uniprot[Pubmed] 17660200 Polyketide synthase genes and the natural products potential of Dictyostelium discoideum.(Bioinformatics) [2007]
3uniprot[Pubmed] 16906151 Biosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid-type III polyketide synthase.(Nat. Chem. Biol.) [2006]

A2TPD4_9FLAO
(A2TPD4)

9e-32

142

26%

Product: 3-oxoacyl-[acyl-carrier-protein (ACP)] synthase III
Gene: MED134_04714
Organism: Dokdonia donghaensis MED134

1uniprot[Pubmed] 17215843
Light stimulates growth of proteorhodopsin-containing marine Flavobacteria.(Nature) [2007]

A2TYE6_9FLAO
(A2TYE6)

2e-31

141

25%

Product: 3-oxoacyl-[acyl-carrier-protein (ACP)] synthase III
Gene: MED152_08615
Organism: Polaribacter sp. MED152

[pubmed all]
1uniprot[Pubmed] 17215843 Light stimulates growth of proteorhodopsin-containing marine Flavobacteria.(Nature) [2007]
2uniprot[Pubmed] 18552178 Genome analysis of the proteorhodopsin-containing marine bacterium Polaribacter sp. MED152 (Flavobacteria).(Proc. Natl. Acad. Sci. U.S.A.) [2008]

E6SG44_INTC7
(E6SG44)

3e-31

140

31%

Product: Chalcone and stilbene synthase domain protein
Gene: Intca_3524
Organism: Intrasporangium calvum (strain ATCC 23552 / DSM 43043 / JCM 3097 / NBRC 12989 / 7 KIP)

1uniprot[Pubmed] 21304734
Complete genome sequence of Intrasporangium calvum type strain (7 KIP).(Stand. Genomic Sci.) [2010]

C6XUK5_PEDHD
(C6XUK5)

3e-31

140

27%

Product: Chalcone and stilbene synthase domain protein
Gene: Phep_1642
Organism: Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / NCIB 9290)

1uniprot
Complete genome sequence of Pedobacter heparinus type strain (HIM 762-3T).(Stand. Genomic Sci.) [2009]

Q2KC78_RHIEC
(Q2KC78)

4e-31

140

29%

Product: Probable chalcone synthase protein
Gene: RHE_CH00744
Organism: Rhizobium etli (strain CFN 42 / ATCC 51251)

1uniprot[Pubmed] 16505379
The partitioned Rhizobium etli genome: genetic and metabolic redundancy in seven interacting replicons.(Proc. Natl. Acad. Sci. U.S.A.) [2006]

C1ANT8_MYCBT
(C1ANT8)

1e-30

138

30%

Product: Putative chalcone synthase
Gene: pks11
JTY_1679
Organism: Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019)

1uniprot[Pubmed] 19200449
Whole genome sequence analysis of Mycobacterium bovis bacillus Calmette-Guerin (BCG) Tokyo 172: a comparative study of BCG vaccine substrains.(Vaccine) [2009]

A1KJ82_MYCBP
(A1KJ82)

1e-30

138

30%

Product: Possible chalcone synthase pks11
Gene: pks11
BCG_1704
Organism: Mycobacterium bovis (strain BCG / Pasteur 1173P2)

1uniprot[Pubmed] 17372194
Genome plasticity of BCG and impact on vaccine efficacy.(Proc. Natl. Acad. Sci. U.S.A.) [2007]