BLAST table : Balhi_00030

DB	UniProtKB

	accession	Evalue	Score	Ident.	link	product	gene	organism	ec
1	Q799B4_9PSEU (Q799B4)	1e-112	407	100%	UniProt GenBank	Putative VanY-type carboxypeptidase	vanY	Amycolatopsis balhimycina
2	D3EYX2_CONWI (D3EYX2)	5e-56	221	70%	UniProt GenBank	Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin	Cwoe_1418	Conexibacter woesei (strain DSM 14684 / JCM 11494 / NBRC 100937 / ID131577)
3	D3PUW8_STANL (D3PUW8)	6e-55	218	64%	UniProt GenBank	Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin	Snas_5359	Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)
4	E9L1F1_9ZZZZ (E9L1F1)	7e-55	217	65%	UniProt GenBank	Putative uncharacterized protein	CA37-7	uncultured organism CA37
5	E9L1K5_9ZZZZ (E9L1K5)	4e-54	215	74%	UniProt GenBank	Putative uncharacterized protein	CA878-6	uncultured organism CA878
6	D3Q172_STANL (D3Q172)	2e-53	212	56%	UniProt GenBank	Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin	Snas_6027	Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)
7	D9VBH7_9ACTO (D9VBH7)	5e-53	211	65%	UniProt GenBank	Peptidase M15B and M15C	SSMG_01110	Streptomyces sp. AA4
8	F4CTK1_9PSEU (F4CTK1)	3e-52	209	67%	UniProt GenBank	Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin	Psed_6410	Pseudonocardia dioxanivorans CB1190
9	D2PMY1_KRIFD (D2PMY1)	5e-52	208	61%	UniProt GenBank	Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin	Kfla_3626	Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399)
10	A3TKZ6_9MICO (A3TKZ6)	8e-50	201	66%	UniProt GenBank	Putative uncharacterized protein	JNB_02745	Janibacter sp. HTCC2649
11	F5XGE4_9ACTO (F5XGE4)	1e-49	200	58%	UniProt GenBank	Peptidase M15 family protein	MLP_00370	Microlunatus phosphovorus NM-1
12	E9L1Q2_9ZZZZ (E9L1Q2)	1e-45	187	53%	UniProt GenBank	Putative uncharacterized protein	CA915-10	uncultured organism CA915
13	F4GZ31_CELFA (F4GZ31)	2e-45	186	55%	UniProt GenBank	Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin	Celf_1891	Cellulomonas fimi (strain ATCC 484 / DSM 20113 / JCM 1341 / NBRC 15513 / NCIMB 8980 / NCTC 7547)
14	D6ALF7_STRFL (D6ALF7)	7e-45	184	61%	UniProt GenBank	Peptidase M15B and M15C	SSGG_06837	Streptomyces roseosporus NRRL 15998
15	D8HIQ6_AMYMU (D8HIQ6)	1e-44	183	66%	UniProt GenBank	D-alanyl-D-alanine carboxypeptidase	AMED_8285	Amycolatopsis mediterranei (strain U-32)
16	D1BRJ9_XYLCX (D1BRJ9)	4e-42	175	64%	UniProt GenBank	Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin	Xcel_1423	Xylanimonas cellulosilytica (strain DSM 15894 / CECT 5975 / LMG 20990 / XIL07)
17	B5GYN5_STRCL (B5GYN5)	7e-33	144	55%	UniProt GenBank	Peptidase M15B and M15C	SSCG_04589	Streptomyces clavuligerus ATCC 27064
18	E2PYF6_STRCL (E2PYF6)	1e-32	144	55%	UniProt GenBank	D-alanyl-D-alanine carboxypeptidase	SCLAV_1099	Streptomyces clavuligerus ATCC 27064
19	B1MP50_MYCA9 (B1MP50)	3e-32	142	54%	UniProt GenBank	Putative VanY-type carboxypeptidase	MAB_2019	Mycobacterium abscessus (strain ATCC 19977 / DSM 44196)
20	A1U9R1_MYCSK (A1U9R1)	5e-31	138	52%	UniProt GenBank	Peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysin	Mkms_0352	Mycobacterium sp. (strain KMS)
21	Q1BF71_MYCSS (Q1BF71)	6e-31	138	52%	UniProt GenBank	Peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysin	Mmcs_0342	Mycobacterium sp. (strain MCS)
22	D9UYK5_9ACTO (D9UYK5)	7e-31	138	54%	UniProt GenBank	Peptidase M15B and M15C	SSMG_06553	Streptomyces sp. AA4
23	A3PTB7_MYCSJ (A3PTB7)	2e-30	136	51%	UniProt GenBank	Peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysin	Mjls_0331	Mycobacterium sp. (strain JLS)
24	C3JGT2_RHOER (C3JGT2)	3e-29	132	51%	UniProt GenBank	D-alanyl-D-alanine carboxypeptidase	RHOER0001_4419	Rhodococcus erythropolis SK121
25	D7AXX4_NOCDD (D7AXX4)	4e-29	132	52%	UniProt GenBank	Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin	Ndas_2611	Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) Actinomadura dassonvillei
26	A1SCW6_NOCSJ (A1SCW6)	1e-28	130	56%	UniProt GenBank	Peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysin	Noca_0106	Nocardioides sp. (strain BAA-499 / JS614)
27	A1TDP5_MYCVP (A1TDP5)	7e-28	128	50%	UniProt GenBank	Peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysin	Mvan_4520	Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1)
28	E6TMX3_MYCSR (E6TMX3)	7e-28	127	50%	UniProt GenBank	D-alanyl-D-alanine carboxypeptidase	Mspyr1_16090	Mycobacterium sp. (strain Spyr1)
29	A4T8Y8_MYCGI (A4T8Y8)	1e-27	127	50%	UniProt GenBank	Peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysin	Mflv_2177	Mycobacterium gilvum (strain PYR-GCK) Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK)
30	F8A2X4_9GAMM (F8A2X4)	2e-27	126	48%	UniProt GenBank	Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin	Celgi_0163	Cellvibrio gilvus ATCC 13127
31	C0ZWC1_RHOE4 (C0ZWC1)	6e-27	124	55%	UniProt GenBank	Putative M15 family peptidase	RER_19480	Rhodococcus erythropolis (strain PR4 / NBRC 100887)	3.4.-.- niceE keggE
32	D5UPZ0_TSUPD (D5UPZ0)	1e-26	124	50%	UniProt GenBank	Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin	Tpau_0104	Tsukamurella paurometabola (strain ATCC 8368 / DSM 20162 / JCM 10117 / NBRC 16120 / NCTC 13040) Corynebacterium paurometabolum
33	D1BKW2_SANKS (D1BKW2)	6e-26	121	48%	UniProt GenBank	D-alanyl-D-alanine carboxypeptidase	Sked_26850	Sanguibacter keddieii (strain ATCC 51767 / DSM 10542 / NCFB 3025 / ST-74)
34	C5BY53_BEUC1 (C5BY53)	2e-25	120	51%	UniProt GenBank	Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin	Bcav_2708	Beutenbergia cavernae (strain ATCC BAA-8 / DSM 12333 / NBRC 16432)
35	A0QTM8_MYCS2 (A0QTM8)	2e-25	119	51%	UniProt GenBank	D-alanyl-D-alanine carboxypeptidase family protein	MSMEG_1900	Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
36	D0LDY2_GORB4 (D0LDY2)	3e-23	112	51%	UniProt GenBank	Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin	Gbro_2514	Gordonia bronchialis (strain ATCC 25592 / DSM 43247 / JCM 3198 / NCTC 10667) Rhodococcus bronchialis
37	Q5YUU3_NOCFA (Q5YUU3)	2e-22	110	51%	UniProt GenBank	Putative uncharacterized protein	NFA_32010	Nocardia farcinica
38	F1YNJ1_9ACTO (F1YNJ1)	4e-21	105	47%	UniProt GenBank	Putative uncharacterized protein	SCNU_17365	Gordonia neofelifaecis NRRL B-59395
39	D2PZY7_KRIFD (D2PZY7)	9e-21	104	59%	UniProt GenBank	Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin	Kfla_0880	Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399)
40	D1BBW9_SANKS (D1BBW9)	1e-20	103	52%	UniProt GenBank	D-alanyl-D-alanine carboxypeptidase	Sked_07970	Sanguibacter keddieii (strain ATCC 51767 / DSM 10542 / NCFB 3025 / ST-74)
41	F6EJT6_9MYCO (F6EJT6)	5e-20	102	43%	UniProt GenBank	Putative uncharacterized protein	AS9A_1662	Amycolicicoccus subflavus DQS3-9A1
42	C7QJI8_CATAD (C7QJI8)	3e-18	96.3	44%	UniProt GenBank	Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin	Caci_2293	Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
43	D5URU3_TSUPD (D5URU3)	2e-17	93.2	44%	UniProt GenBank	Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin	Tpau_2545	Tsukamurella paurometabola (strain ATCC 8368 / DSM 20162 / JCM 10117 / NBRC 16120 / NCTC 13040) Corynebacterium paurometabolum
44	Q7WZ84_9ACTO (Q7WZ84)	5e-15	85.1	48%	UniProt GenBank	Putative VanY-type carboxypeptidase	dbv7	Nonomuraea sp. ATCC 39727
45	C8XJ67_NAKMY (C8XJ67)	2e-14	83.2	37%	UniProt GenBank	Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin	Namu_2154	Nakamurella multipartita (strain ATCC 700099 / DSM 44233 / JCM 9543 / Y-104) Microsphaera multipartita
46	D9V402_9ACTO (D9V402)	6e-11	71.6	44%	UniProt GenBank	Putative uncharacterized protein	SSMG_02649	Streptomyces sp. AA4
47	D9VBZ5_9ACTO (D9VBZ5)	5e-10	68.9	45%	UniProt GenBank	Putative uncharacterized protein	SSMG_03383	Streptomyces sp. AA4
48	F0L6I8_AGRSH (F0L6I8)	1e-09	67.8	45%	UniProt GenBank	Minor tail protein	AGROH133_06876	Agrobacterium sp. (strain H13-3) Rhizobium lupini (strain H13-3)
49	D9V5K5_9ACTO (D9V5K5)	2e-09	67	39%	UniProt GenBank	Putative uncharacterized protein	SSMG_02784	Streptomyces sp. AA4
50	F7X3I5_RHIME (F7X3I5)	4e-08	62.4	41%	UniProt GenBank	Phage-related minor tail protein	SM11_chr2328	Sinorhizobium meliloti SM11
51	D9R853_CLOSW (D9R853)	8e-08	61.6	36%	UniProt GenBank	Serine-type D-Ala-D-Ala carboxypeptidase	Closa_1198	Clostridium saccharolyticum (strain ATCC 35040 / DSM 2544 / NRCC 2533 / WM1)	3.4.16.4 niceE keggE
52	A7VSL6_9CLOT (A7VSL6)	2e-07	60.1	30%	UniProt GenBank	Putative uncharacterized protein	CLOLEP_01557	Clostridium leptum DSM 753
53	Q9L8Y3_ENTFA (Q9L8Y3)	2e-07	60.1	32%	UniProt GenBank	VanY protein VanYB	vanYB vanY	Enterococcus faecalis Streptococcus faecalis
54	Q7BI95_ENTFC (Q7BI95)	2e-07	60.1	32%	UniProt GenBank	D,D-carboxypeptidase VanYB	vanYB2 vanYB	Enterococcus faecium Streptococcus faecium
55	Q56R51_9CLOT (Q56R51)	2e-07	60.1	32%	UniProt GenBank	VanYX	vanYB	Clostridium sp. CCRI-9842
56	Q32ZB2_9ACTN (Q32ZB2)	2e-07	60.1	32%	UniProt GenBank	VanYB	vanYB	Eggerthella lenta
57	Q32ZA3_9CLOT (Q32ZA3)	2e-07	60.1	32%	UniProt GenBank	VanYB	vanYB	Clostridium sp. MLG245
58	Q9AHN5_ENTFC (Q9AHN5)	2e-07	59.7	32%	UniProt GenBank	D,D-carboxypeptidase	vanYB2	Enterococcus faecium Streptococcus faecium
59	C7WYV6_ENTFA (C7WYV6)	3e-07	59.7	33%	UniProt GenBank	D,D-carboxypeptidase	EFGG_02749	Enterococcus faecalis Merz96
60	VANY_ENTFA (Q47746)	3e-07	59.7	33%	UniProt GenBank	D-alanyl-D-alanine carboxypeptidase	vanYB EF_2297	Enterococcus faecalis Streptococcus faecalis	3.4.16.4 niceE keggE
61	D0APH8_ENTFC (D0APH8)	3e-07	59.7	32%	UniProt GenBank	VanY protein	EFXG_01483	Enterococcus faecium C68
62	D4L4C9_9FIRM (D4L4C9)	6e-07	58.5	31%	UniProt GenBank	D-alanyl-D-alanine carboxypeptidase	RO1_43140	Roseburia intestinalis XB6B4	3.4.16.4 niceE keggE
63	C0X1U9_ENTFA (C0X1U9)	6e-07	58.5	34%	UniProt GenBank	Serine family D-Ala-D-Ala carboxypeptidase	vanYB2 HMPREF0348_0484	Enterococcus faecalis TX0104	3.4.16.4 niceE keggE
64	D3F8V5_CONWI (D3F8V5)	9e-07	58.2	36%	UniProt GenBank	Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin	Cwoe_4537	Conexibacter woesei (strain DSM 14684 / JCM 11494 / NBRC 100937 / ID131577)
65	E0GB12_ENTFA (E0GB12)	2e-06	57	28%	UniProt GenBank	Serine-type D-Ala-D-Ala carboxypeptidase	HMPREF9514_00843	Enterococcus faecalis TX0855
66	C7VJW7_ENTFA (C7VJW7)	2e-06	57	28%	UniProt GenBank	D,D-carboxypeptidase	EFHG_01372	Enterococcus faecalis HIP11704
67	F8C7C4_MYXFU (F8C7C4)	2e-06	56.6	34%	UniProt GenBank	Penicillin-resistant DD-carboxypeptidase	LILAB_06005	Myxococcus fulvus
68	F2NUJ4_TRES6 (F2NUJ4)	2e-06	56.6	32%	UniProt GenBank	Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin	Tresu_0616	Treponema succinifaciens (strain ATCC 33096 / DSM 2489 / 6091)
69	E0RNI8_SPITD (E0RNI8)	2e-06	56.6	39%	UniProt GenBank	Putative uncharacterized protein	STHERM_c16390	Spirochaeta thermophila (strain ATCC 49972 / DSM 6192 / RI 19.B1)
70	F3R1X7_ENTFA (F3R1X7)	2e-06	56.6	28%	UniProt GenBank	Serine-type D-Ala-D-Ala carboxypeptidase	HMPREF9520_00986	Enterococcus faecalis TX1467
71	F2NV42_TRES6 (F2NV42)	3e-06	56.2	32%	UniProt GenBank	Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin	Tresu_0319	Treponema succinifaciens (strain ATCC 33096 / DSM 2489 / 6091)
72	E6JTR1_9SPIO (E6JTR1)	3e-06	56.2	36%	UniProt GenBank	Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin	SpithDRAFT_0663	Spirochaeta thermophila DSM 6578
73	Q97E20_CLOAB (Q97E20)	3e-06	56.2	29%	UniProt GenBank	D-alanyl-D-alanine carboxypeptidase family hydrolase, YODJ B.subtilis ortholog	CA_C3297	Clostridium acetobutylicum
74	F0K8V5_CLOAE (F0K8V5)	3e-06	56.2	29%	UniProt GenBank	D-alanyl-D-alanine carboxypeptidase family hydrolase, YODJ	CEA_G3299	Clostridium acetobutylicum (strain EA 2018)
75	F7ZPP6_CLOAB (F7ZPP6)	3e-06	56.2	29%	UniProt GenBank	D-alanyl-D-alanine carboxypeptidase	yodJ SMB_G3334	Clostridium acetobutylicum DSM 1731
76	C0BEB6_9FIRM (C0BEB6)	4e-06	55.8	28%	UniProt GenBank	Putative uncharacterized protein	COPCOM_03528	Coprococcus comes ATCC 27758
77	E9SD74_RUMAL (E9SD74)	4e-06	55.8	33%	UniProt GenBank	Serine-type D-Ala-D-Ala carboxypeptidase	CUS_6090	Ruminococcus albus 8	3.4.16.4 niceE keggE
78	Q1DEU4_MYXXD (Q1DEU4)	6e-06	55.1	32%	UniProt GenBank	Penicillin-resistant DD-carboxypeptidase	pdcA MXAN_0560	Myxococcus xanthus (strain DK 1622)
79	Q9S596_MYXXA (Q9S596)	6e-06	55.1	32%	UniProt GenBank	Penicillin-resistant DD-carboxypeptidase	pdcA	Myxococcus xanthus
80	F2MUF7_ENTFO (F2MUF7)	1e-05	54.3	27%	UniProt GenBank	Serine-type D-Ala-D-Ala carboxypeptidase	vanYB OG1RF_12161	Enterococcus faecalis (strain ATCC 47077 / OG1RF)	3.4.16.4 niceE keggE
81	F0PDZ9_ENTF6 (F0PDZ9)	1e-05	54.3	27%	UniProt GenBank	D-alanyl-D-alanine carboxypeptidase	pbp5 EF62_2955	Enterococcus faecalis (strain 62)	3.4.16.4 niceE keggE
82	E6HUG3_ENTFA (E6HUG3)	1e-05	54.3	27%	UniProt GenBank	Serine-type D-Ala-D-Ala carboxypeptidase	HMPREF9508_01211	Enterococcus faecalis TX0312
83	E6GJ54_ENTFA (E6GJ54)	1e-05	54.3	27%	UniProt GenBank	Serine-type D-Ala-D-Ala carboxypeptidase	HMPREF9501_00954	Enterococcus faecalis TX0027
84	E6G090_ENTFA (E6G090)	1e-05	54.3	27%	UniProt GenBank	Serine-type D-Ala-D-Ala carboxypeptidase	HMPREF9516_00022	Enterococcus faecalis TX1302
85	E6FSZ3_ENTFA (E6FSZ3)	1e-05	54.3	27%	UniProt GenBank	Serine-type D-Ala-D-Ala carboxypeptidase	HMPREF9518_00270	Enterococcus faecalis TX1342
86	E6F418_ENTFA (E6F418)	1e-05	54.3	27%	UniProt GenBank	Serine-type D-Ala-D-Ala carboxypeptidase	HMPREF9502_00382	Enterococcus faecalis TX0031
87	E2Y1H3_ENTFA (E2Y1H3)	1e-05	54.3	27%	UniProt GenBank	Serine-type D-Ala-D-Ala carboxypeptidase	HMPREF9504_00223	Enterococcus faecalis TX0102
88	E1EQC9_ENTFA (E1EQC9)	1e-05	54.3	27%	UniProt GenBank	Serine-type D-Ala-D-Ala carboxypeptidase	HMPREF0347_6398	Enterococcus faecalis TUSoD Ef11	3.4.16.4 niceE keggE
89	E0H1F3_ENTFA (E0H1F3)	1e-05	54.3	27%	UniProt GenBank	Serine-type D-Ala-D-Ala carboxypeptidase	HMPREF9505_00387	Enterococcus faecalis TX0109
90	E0GM90_ENTFA (E0GM90)	1e-05	54.3	27%	UniProt GenBank	Serine-type D-Ala-D-Ala carboxypeptidase	HMPREF9521_01785	Enterococcus faecalis TX2134
91	E0G0L8_ENTFA (E0G0L8)	1e-05	54.3	27%	UniProt GenBank	Serine-type D-Ala-D-Ala carboxypeptidase	HMPREF9498_00474	Enterococcus faecalis TX4248
92	D4UX62_ENTFA (D4UX62)	1e-05	54.3	27%	UniProt GenBank	Serine-type D-Ala-D-Ala carboxypeptidase	CUI_1725	Enterococcus faecalis PC1.1
93	D4MDH5_9ENTE (D4MDH5)	1e-05	54.3	27%	UniProt GenBank	D-alanyl-D-alanine carboxypeptidase	ENT_19710	Enterococcus sp. 7L76	3.4.16.4 niceE keggE
94	C7WRT8_ENTFA (C7WRT8)	1e-05	54.3	27%	UniProt GenBank	D,D-carboxypeptidase	EFFG_01970	Enterococcus faecalis ARO1/DG
95	C7WI49_ENTFA (C7WI49)	1e-05	54.3	27%	UniProt GenBank	D,D-carboxypeptidase	EFEG_02430	Enterococcus faecalis DS5
96	C7W9E4_ENTFA (C7W9E4)	1e-05	54.3	27%	UniProt GenBank	VanYB	EFIG_01231	Enterococcus faecalis JH1
97	C7CUB4_ENTFA (C7CUB4)	1e-05	54.3	27%	UniProt GenBank	D,D-carboxypeptidase	EFAG_00033	Enterococcus faecalis T1
98	D5HKK6_ENTFC (D5HKK6)	1e-05	53.9	26%	UniProt GenBank	Metallo D,D carboxypeptidase	ddcY	Enterococcus faecium Streptococcus faecium
99	D4RCM8_ENTFC (D4RCM8)	1e-05	53.9	26%	UniProt GenBank	D-alanyl-D-alanine carboxypeptidase	EfmE1636_2597	Enterococcus faecium E1636
100	D3LH84_ENTFC (D3LH84)	1e-05	53.9	26%	UniProt GenBank	M15 family muramoylpentapeptide carboxypeptidase	EDAG_01553	Enterococcus faecium D344SRF

accession

alignment

Evalue

Score

Ident.

link

information

pubmed

Q799B4_9PSEU
(Q799B4)

1e-112

407

100%

Product: Putative VanY-type carboxypeptidase
Gene: vanY
Organism: Amycolatopsis balhimycina

[pubmed all]
1uniprot[Pubmed] 10390204 [Medline] 99318579 Identification and analysis of the balhimycin biosynthetic gene cluster and its use for manipulating glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908.(Antimicrob. Agents Chemother.) [1999]
2uniprot[Pubmed] 11932455 [Medline] 21930292 Nonribosomal biosynthesis of vancomycin-type antibiotics: a heptapeptide backbone and eight peptide synthetase modules.(Microbiology) [2002]
3uniprot[Pubmed] 11495926 [Medline] 21486455 A polyketide synthase in glycopeptide biosynthesis: the biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine.(J. Biol. Chem.) [2001]
4uniprot[Pubmed] 12404385 The biosynthesis of vancomycin-type glycopeptide antibiotics - the order of cyclization steps.(Angew. Chem. Int. Ed. Engl.) [2001]
5uniprot[Pubmed] 11880037 [Medline] 21869276 Glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908: function of a halogenase and a haloperoxidase/perhydrolase.(Chem. Biol.) [2002]
6uniprot Precursor-directed biosynthesis for the generation of novel glycopetides.(Ernst Schering Res. Found. Workshop) [2005]

D3PUW8_STANL
(D3PUW8)

6e-55

218

64%

Product: Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin
Gene: Snas_5359
Organism: Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)

1uniprot
Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21T).(Stand. Genomic Sci.) [2009]

E9L1F1_9ZZZZ
(E9L1F1)

7e-55

217

65%

Product: Putative uncharacterized protein
Gene: CA37-7
Organism: uncultured organism CA37

1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]

E9L1K5_9ZZZZ
(E9L1K5)

4e-54

215

74%

Product: Putative uncharacterized protein
Gene: CA878-6
Organism: uncultured organism CA878

1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]

D3Q172_STANL
(D3Q172)

2e-53

212

56%

Product: Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin
Gene: Snas_6027
Organism: Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)

1uniprot
Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21T).(Stand. Genomic Sci.) [2009]

A3TKZ6_9MICO
(A3TKZ6)

8e-50

201

66%

Product: Putative uncharacterized protein
Gene: JNB_02745
Organism: Janibacter sp. HTCC2649

1uniprot[Pubmed] 21075932
Genome sequence of the Marine Janibacter Sp. Strain HTCC2649.(J. Bacteriol.) [2011]

E9L1Q2_9ZZZZ
(E9L1Q2)

1e-45

187

53%

Product: Putative uncharacterized protein
Gene: CA915-10
Organism: uncultured organism CA915

1uniprot[Pubmed] 20945895
Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010]

D8HIQ6_AMYMU
(D8HIQ6)

1e-44

183

66%

Product: D-alanyl-D-alanine carboxypeptidase
Gene: AMED_8285
Organism: Amycolatopsis mediterranei (strain U-32)

1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]

E2PYF6_STRCL
(E2PYF6)

1e-32

144

55%

Product: D-alanyl-D-alanine carboxypeptidase
Gene: SCLAV_1099
Organism: Streptomyces clavuligerus ATCC 27064

1uniprot[Pubmed] 20624727
The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]

D7AXX4_NOCDD
(D7AXX4)

4e-29

132

52%

Product: Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin
Gene: Ndas_2611
Organism: Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei

1uniprot
Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010]

C0ZWC1_RHOE4
(C0ZWC1)

6e-27

124

55%

Product: Putative M15 family peptidase
Gene: RER_19480
Organism: Rhodococcus erythropolis (strain PR4 / NBRC 100887)

1uniprot
Sequence analysis of three plasmids harboured in Rhodococcus erythropolis strain PR4.(Environ. Microbiol.) [2006]

D1BKW2_SANKS
(D1BKW2)

6e-26

121

48%

Product: D-alanyl-D-alanine carboxypeptidase
Gene: Sked_26850
Organism: Sanguibacter keddieii (strain ATCC 51767 / DSM 10542 / NCFB 3025 / ST-74)

1uniprot
Complete genome sequence of Sanguibacter keddieii type strain (ST-74T).(Stand. Genomic Sci.) [2009]

C5BY53_BEUC1
(C5BY53)

2e-25

120

51%

Product: Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin
Gene: Bcav_2708
Organism: Beutenbergia cavernae (strain ATCC BAA-8 / DSM 12333 / NBRC 16432)

1uniprot[Pubmed] 21304633
Complete genome sequence of Beutenbergia cavernae type strain (HKI 0122).(Stand. Genomic Sci.) [2009]

Q5YUU3_NOCFA
(Q5YUU3)

2e-22

110

51%

Product: Putative uncharacterized protein
Gene: NFA_32010
Organism: Nocardia farcinica

1uniprot[Pubmed] 15466710
The complete genomic sequence of Nocardia farcinica IFM 10152.(Proc. Natl. Acad. Sci. U.S.A.) [2004]

D1BBW9_SANKS
(D1BBW9)

1e-20

103

52%

Product: D-alanyl-D-alanine carboxypeptidase
Gene: Sked_07970
Organism: Sanguibacter keddieii (strain ATCC 51767 / DSM 10542 / NCFB 3025 / ST-74)

1uniprot
Complete genome sequence of Sanguibacter keddieii type strain (ST-74T).(Stand. Genomic Sci.) [2009]

C7QJI8_CATAD
(C7QJI8)

3e-18

96.3

44%

Product: Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin
Gene: Caci_2293
Organism: Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)

1uniprot
Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009]

Q7WZ84_9ACTO
(Q7WZ84)

5e-15

85.1

48%

Product: Putative VanY-type carboxypeptidase
Gene: dbv7
Organism: Nonomuraea sp. ATCC 39727

1uniprot[Pubmed] 12837387 [Medline] 22721464
The gene cluster for the biosynthesis of the glycopeptide antibiotic A40926 by nonomuraea species.(Chem. Biol.) [2003]

F0L6I8_AGRSH
(F0L6I8)

1e-09

67.8

45%

Product: Minor tail protein
Gene: AGROH133_06876
Organism: Agrobacterium sp. (strain H13-3)
Rhizobium lupini (strain H13-3)

1uniprot[Pubmed] 21329740
Complete genome sequencing of Agrobacterium sp H13-3, the former Rhizobium lupini H13-3, reveals a tripartite genome consisting of a circular and a linear chromosome and an accessory plasmid but lacking a tumor-inducing Ti-plasmid.(J. Biotechnol.) [2011]

F7X3I5_RHIME
(F7X3I5)

4e-08

62.4

41%

Product: Phage-related minor tail protein
Gene: SM11_chr2328
Organism: Sinorhizobium meliloti SM11

1uniprot[Pubmed] 21396969
The complete genome sequence of the dominant Sinorhizobium meliloti field isolate SM11 extends the S. meliloti pan-genome.(J. Biotechnol.) [2011]

Q9L8Y3_ENTFA
(Q9L8Y3)

2e-07

60.1

32%

Product: VanY protein
VanYB
Gene: vanYB
vanY
Organism: Enterococcus faecalis
Streptococcus faecalis

[pubmed all]
1uniprot[Pubmed] 10846226 [Medline] 20307505 Characterization of transposon Tn1549, conferring VanB-type resistance in Enterococcus spp.(Microbiology) [2000]
2uniprot[Pubmed] 19029325 Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2201, encoding erythromycin resistance and cytolysin (Hly/Bac).(Antimicrob. Agents Chemother.) [2009]

Q7BI95_ENTFC
(Q7BI95)

2e-07

60.1

32%

Product: D,D-carboxypeptidase
VanYB
Gene: vanYB2
vanYB
Organism: Enterococcus faecium
Streptococcus faecium

[pubmed all]
1uniprot[Pubmed] 11230450 [Medline] 21142680 Possible horizontal transfer of the vanB2 gene among genetically diverse strains of vancomycin-resistant Enterococcus faecium in a Korean hospital.(J. Clin. Microbiol.) [2001]
2uniprot[Pubmed] 19273676 VanB-type Enterococcus faecium clinical isolate successively inducibly resistant to, dependent on, and constitutively resistant to vancomycin.(Antimicrob. Agents Chemother.) [2009]
3uniprot[Pubmed] 15616278 Comparison of three PCR primer sets for identification of vanB gene carriage in feces and correlation with carriage of vancomycin-resistant enterococci: interference by vanB-containing anaerobic bacilli.(Antimicrob. Agents Chemother.) [2005]
4uniprot Molecular characterization of vanB elements in naturally-occurring gut anaerobes.(Antimicrob. Agents Chemother.) [2005]
5uniprot[Pubmed] 14617162 [Medline] 22983133 A six amino acid deletion, partially overlapping the VanSB G2 ATP-binding motif, leads to constitutive glycopeptide resistance in VanB-type Enterococcus faecium.(Mol. Microbiol.) [2003]
6uniprot[Pubmed] 11376048 [Medline] 21270249 High prevalence of VanB2 vancomycin-resistant Enterococcus faecium in Taiwan.(J. Clin. Microbiol.) [2001]

Q56R51_9CLOT
(Q56R51)

2e-07

60.1

32%

Product: VanYX
Gene: vanYB
Organism: Clostridium sp. CCRI-9842

1uniprot[Pubmed] 15731199
Characterization of a Tn5382-like transposon containing the vanB2 gene cluster in a Clostridium strain isolated from human faeces.(J. Antimicrob. Chemother.) [2005]

Q32ZB2_9ACTN
(Q32ZB2)

2e-07

60.1

32%

Product: VanYB
Gene: vanYB
Organism: Eggerthella lenta

1uniprot[Pubmed] 15616278
Comparison of three PCR primer sets for identification of vanB gene carriage in feces and correlation with carriage of vancomycin-resistant enterococci: interference by vanB-containing anaerobic bacilli.(Antimicrob. Agents Chemother.) [2005]

2uniprot
Molecular characterization of vanB elements in naturally-occurring gut anaerobes.(Antimicrob. Agents Chemother.) [2005]

Q32ZA3_9CLOT
(Q32ZA3)

2e-07

60.1

32%

Product: VanYB
Gene: vanYB
Organism: Clostridium sp. MLG245

2uniprot
Molecular characterization of vanB elements in naturally-occurring gut anaerobes.(Antimicrob. Agents Chemother.) [2005]

Q9AHN5_ENTFC
(Q9AHN5)

2e-07

59.7

32%

Product: D,D-carboxypeptidase
Gene: vanYB2
Organism: Enterococcus faecium
Streptococcus faecium

1uniprot[Pubmed] 11230450 [Medline] 21142680
Possible horizontal transfer of the vanB2 gene among genetically diverse strains of vancomycin-resistant Enterococcus faecium in a Korean hospital.(J. Clin. Microbiol.) [2001]

VANY_ENTFA
(Q47746)

3e-07

59.7

33%

Product: D-alanyl-D-alanine carboxypeptidase
Gene: vanYB
EF_2297
Organism: Enterococcus faecalis
Streptococcus faecalis

[pubmed all]
1uniprot[Pubmed] 8631706 [Medline] 96200099 Regulation of VanB-type vancomycin resistance gene expression by the VanS(B)-VanR(B) two-component regulatory system in Enterococcus faecalis V583.(J. Bacteriol.) [1996]
2uniprot[Pubmed] 12663927 [Medline] 22550857 Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus faecalis.(Science) [2003]

E0RNI8_SPITD
(E0RNI8)

2e-06

56.6

39%

Product: Putative uncharacterized protein
Gene: STHERM_c16390
Organism: Spirochaeta thermophila (strain ATCC 49972 / DSM 6192 / RI 19.B1)

1uniprot[Pubmed] 20935097
Genome sequence of the polysaccharide-degrading, thermophilic anaerobe Spirochaeta thermophila DSM 6192.(J. Bacteriol.) [2010]

Q97E20_CLOAB
(Q97E20)

3e-06

56.2

29%

Product: D-alanyl-D-alanine carboxypeptidase family hydrolase, YODJ B.subtilis ortholog
Gene: CA_C3297
Organism: Clostridium acetobutylicum

1uniprot[Pubmed] 11466286 [Medline] 21359325
Genome sequence and comparative analysis of the solvent-producing bacterium Clostridium acetobutylicum.(J. Bacteriol.) [2001]

F0K8V5_CLOAE
(F0K8V5)

3e-06

56.2

29%

Product: D-alanyl-D-alanine carboxypeptidase family hydrolase, YODJ
Gene: CEA_G3299
Organism: Clostridium acetobutylicum (strain EA 2018)

1uniprot[Pubmed] 21284892
Comparative genomic and transcriptomic analysis revealed genetic characteristics related to solvent formation and xylose utilization in Clostridium acetobutylicum EA 2018.(BMC Genomics) [2011]

Q1DEU4_MYXXD
(Q1DEU4)

6e-06

55.1

32%

Product: Penicillin-resistant DD-carboxypeptidase
Gene: pdcA
MXAN_0560
Organism: Myxococcus xanthus (strain DK 1622)

1uniprot[Pubmed] 17015832
Evolution of sensory complexity recorded in a myxobacterial genome.(Proc. Natl. Acad. Sci. U.S.A.) [2006]

Q9S596_MYXXA
(Q9S596)

6e-06

55.1

32%

Product: Penicillin-resistant DD-carboxypeptidase
Gene: pdcA
Organism: Myxococcus xanthus

1uniprot[Pubmed] 10419975 [Medline] 99350441
Molecular cloning, sequence analysis, and characterization of a penicillin-resistant DD-carboxypeptidase of Myxococcus xanthus.(J. Bacteriol.) [1999]

F2MUF7_ENTFO
(F2MUF7)

1e-05

54.3

27%

Product: Serine-type D-Ala-D-Ala carboxypeptidase
Gene: vanYB
OG1RF_12161
Organism: Enterococcus faecalis (strain ATCC 47077 / OG1RF)

1uniprot[Pubmed] 18611278
Large scale variation in Enterococcus faecalis illustrated by the genome analysis of strain OG1RF.(Genome Biol.) [2008]

F0PDZ9_ENTF6
(F0PDZ9)

1e-05

54.3

27%

Product: D-alanyl-D-alanine carboxypeptidase
Gene: pbp5
EF62_2955
Organism: Enterococcus faecalis (strain 62)

1uniprot[Pubmed] 21398545
Complete genome sequence of the commensal Enterococcus faecalis 62, isolated from a healthy Norwegian infant.(J. Bacteriol.) [2011]

D5HKK6_ENTFC
(D5HKK6)

1e-05

53.9

26%

Product: Metallo D,D carboxypeptidase
Gene: ddcY
Organism: Enterococcus faecium
Streptococcus faecium

1uniprot[Pubmed] 20025663
Activation of the L,D-transpeptidation peptidoglycan cross-linking pathway by a metallo-D,D-carboxypeptidase in Enterococcus faecium.(Mol. Microbiol.) [2010]

D4RCM8_ENTFC
(D4RCM8)

1e-05

53.9

26%

Product: D-alanyl-D-alanine carboxypeptidase
Gene: EfmE1636_2597
Organism: Enterococcus faecium E1636

1uniprot[Pubmed] 20398277
Pyrosequencing-based comparative genome analysis of the nosocomial pathogen Enterococcus faecium and identification of a large transferable pathogenicity island.(BMC Genomics) [2010]