BLAST table : A4092_00280

DB	UniProtKB

	accession	Evalue	Score	Ident.	link	product	gene	organism	ec
1	Q7WZ69_9ACTO (Q7WZ69)	0.0	830	100%	UniProt GenBank	Putative sensory kinase	dbv22	Nonomuraea sp. ATCC 39727
2	D7C2P2_STRBB (D7C2P2)	9e-82	308	50%	UniProt GenBank	Histidine kinase	SBI_02804	Streptomyces bingchenggensis (strain BCW-1)
3	E2D2F1_9BACT (E2D2F1)	1e-75	288	43%	UniProt GenBank	Histidine kinase		uncultured soil bacterium
4	E3J679_FRASU (E3J679)	1e-69	268	40%	UniProt GenBank	Integral membrane sensor signal transduction histidine kinase	FraEuI1c_1441	Frankia sp. (strain EuI1c)
5	C4RGY9_9ACTO (C4RGY9)	1e-64	252	41%	UniProt GenBank	Two-component system sensor kinase	MCAG_00665	Micromonospora sp. ATCC 39149
6	Q47NJ6_THEFY (Q47NJ6)	2e-63	247	38%	UniProt GenBank	ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal	Tfu_1940	Thermobifida fusca (strain YX)
7	E4NI79_KITSK (E4NI79)	2e-62	244	39%	UniProt GenBank	Putative two-component system sensor kinase	cutS KSE_54340	Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054) Streptomyces setae
8	D3CVH7_9ACTO (D3CVH7)	2e-62	244	40%	UniProt GenBank	Histidine kinase	FrEUN1fDRAFT_1523	Frankia sp. EUN1f
9	D7C512_STRBB (D7C512)	7e-62	242	43%	UniProt GenBank	Histidine kinase	SBI_05118	Streptomyces bingchenggensis (strain BCW-1)
10	C7PZZ7_CATAD (C7PZZ7)	5e-61	239	38%	UniProt GenBank	Histidine kinase	Caci_6644	Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
11	B1VXN2_STRGG (B1VXN2)	3e-60	237	37%	UniProt GenBank	Putative two-component system sensor kinase	SGR_1669	Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
12	F4F149_VERMA (F4F149)	4e-60	236	40%	UniProt GenBank	Histidine kinase	VAB18032_07925	Verrucosispora maris (strain AB-18-032)
13	B5H8Q7_STRPR (B5H8Q7)	5e-60	236	37%	UniProt GenBank	Sensor protein cutS	SSDG_01629	Streptomyces pristinaespiralis ATCC 25486
14	D2PW06_KRIFD (D2PW06)	4e-59	233	37%	UniProt GenBank	Histidine kinase	Kfla_0541	Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399)
15	D1AC04_THECD (D1AC04)	9e-59	232	41%	UniProt GenBank	Histidine kinase	Tcur_1695	Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
16	D6Y3D2_THEBD (D6Y3D2)	1e-58	232	39%	UniProt GenBank	Histidine kinase	Tbis_2297	Thermobispora bispora (strain ATCC 19993 / DSM 43833 / CBS 139.67 / JCM 10125 / NBRC 14880 / R51)
17	E0KH19_STRVO (E0KH19)	1e-58	232	37%	UniProt GenBank	Integral membrane sensor signal transduction histidine kinase	StrviDRAFT_1946	Streptomyces violaceusniger Tu 4113
18	F2R814_STRVP (F2R814)	4e-58	230	36%	UniProt GenBank	Two-component sensor	SVEN_5537	Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
19	Q2JA80_FRASC (Q2JA80)	4e-58	230	40%	UniProt GenBank	Periplasmic sensor signal transduction histidine kinase	Francci3_2445	Frankia sp. (strain CcI3)
20	D2PVJ9_KRIFD (D2PVJ9)	2e-57	228	37%	UniProt GenBank	Histidine kinase	Kfla_6236	Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399)
21	B5GUQ2_STRCL (B5GUQ2)	3e-57	227	37%	UniProt GenBank	Sensor protein Sensor protein cutS	SCLAV_4787 SSCG_03037	Streptomyces clavuligerus ATCC 27064
22	D7CAW3_STRBB (D7CAW3)	3e-57	227	36%	UniProt GenBank	Integral membrane sensor signal transduction histidine kinase	SBI_05560	Streptomyces bingchenggensis (strain BCW-1)
23	D1XGS0_9ACTO (D1XGS0)	4e-57	226	35%	UniProt GenBank	Histidine kinase	SACTEDRAFT_1971	Streptomyces sp. SA3_actE
24	D2AZF0_STRRD (D2AZF0)	6e-57	226	37%	UniProt GenBank	Integral membrane sensor signal transduction histidine kinase	Sros_0303	Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
25	D7B0R0_NOCDD (D7B0R0)	1e-56	225	39%	UniProt GenBank	Integral membrane sensor signal transduction histidine kinase	Ndas_2884	Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) Actinomadura dassonvillei
26	E9UYD9_9ACTO (E9UYD9)	7e-56	223	40%	UniProt GenBank	Histidine kinase	NBCG_03802	Nocardioidaceae bacterium Broad-1
27	D9W1S9_9ACTO (D9W1S9)	1e-55	221	37%	UniProt GenBank	Two-component system sensor kinase	SSNG_05374	Streptomyces sp. C
28	E8W504_STRFA (E8W504)	1e-55	221	35%	UniProt GenBank	Integral membrane sensor signal transduction histidine kinase	Sfla_1505	Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
29	D9W9Q3_9ACTO (D9W9Q3)	2e-55	221	37%	UniProt GenBank	Histidine kinase	SSOG_02431	Streptomyces himastatinicus ATCC 53653
30	D7C8J9_STRBB (D7C8J9)	2e-55	221	38%	UniProt GenBank	Putative two-component system sensor kinase	cutS SBI_03267	Streptomyces bingchenggensis (strain BCW-1)
31	D6ATB5_STRFL (D6ATB5)	3e-55	220	36%	UniProt GenBank	Two-component system sensor kinase	SSGG_05559	Streptomyces roseosporus NRRL 15998
32	D6TUT5_9CHLR (D6TUT5)	9e-55	219	40%	UniProt GenBank	Integral membrane sensor signal transduction histidine kinase	Krac_6444	Ktedonobacter racemifer DSM 44963
33	D1XLA4_9ACTO (D1XLA4)	2e-54	218	36%	UniProt GenBank	Histidine kinase	SACTEDRAFT_3464	Streptomyces sp. SA3_actE
34	D3Q036_STANL (D3Q036)	2e-54	218	35%	UniProt GenBank	Histidine kinase	Snas_5938	Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)
35	B4V8P2_9ACTO (B4V8P2)	4e-54	217	36%	UniProt GenBank	Two-component system sensor kinase	SSAG_04120	Streptomyces sp. Mg1
36	A8L3M1_FRASN (A8L3M1)	5e-54	216	35%	UniProt GenBank	Integral membrane sensor signal transduction histidine kinase	Franean1_6947	Frankia sp. (strain EAN1pec)
37	D7B079_NOCDD (D7B079)	1e-53	215	39%	UniProt GenBank	Integral membrane sensor signal transduction histidine kinase	Ndas_4783	Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) Actinomadura dassonvillei
38	C4RH84_9ACTO (C4RH84)	1e-53	215	37%	UniProt GenBank	Periplasmic sensor signal transduction histidine kinase	MCAG_00760	Micromonospora sp. ATCC 39149
39	Q54293_STRHY (Q54293)	2e-53	214	36%	UniProt GenBank	Sensory protein kinase	orfS	Streptomyces hygroscopicus
40	D5SL45_STRCL (D5SL45)	2e-53	214	41%	UniProt GenBank	Sensor protein	SCLAV_p1152	Streptomyces clavuligerus ATCC 27064
41	E8WD17_STRFA (E8WD17)	4e-53	213	36%	UniProt GenBank	Integral membrane sensor signal transduction histidine kinase	Sfla_3263	Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
42	A1TBS1_MYCVP (A1TBS1)	7e-53	213	36%	UniProt GenBank	Integral membrane sensor signal transduction histidine kinase	Mvan_3840	Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1)
43	D2AR60_STRRD (D2AR60)	3e-52	211	37%	UniProt GenBank	Integral membrane sensor signal transduction histidine kinase	Sros_5650	Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
44	B5GU89_STRCL (B5GU89)	3e-52	211	39%	UniProt GenBank	Sensor protein Sensory protein kinase	SCLAV_3019 SSCG_02913	Streptomyces clavuligerus ATCC 27064
45	C7Q499_CATAD (C7Q499)	3e-52	210	38%	UniProt GenBank	Histidine kinase	Caci_1033	Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
46	D2B5H6_STRRD (D2B5H6)	3e-52	210	35%	UniProt GenBank	Signal transduction histidine kinase-like protein	Sros_6772	Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
47	D6ARL2_STRFL (D6ARL2)	7e-52	209	37%	UniProt GenBank	Sensor protein cutS	SSGG_03254	Streptomyces roseosporus NRRL 15998
48	C6WAL1_ACTMD (C6WAL1)	9e-52	209	38%	UniProt GenBank	Histidine kinase	Amir_1527	Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
49	D6BB50_9ACTO (D6BB50)	9e-52	209	36%	UniProt GenBank	Two-component system sensor kinase	SSHG_04920	Streptomyces albus J1074
50	B5H151_STRCL (B5H151)	1e-51	209	41%	UniProt GenBank	Integral membrane sensor signal transduction histidine kinase	SSCG_05325	Streptomyces clavuligerus ATCC 27064
51	F8JQP1_STRCT (F8JQP1)	2e-51	208	37%	UniProt GenBank	Sensor protein cutS	cutS SCAT_4633	Streptomyces cattleya	2.7.13.3 niceE keggE
52	D5ZRW6_9ACTO (D5ZRW6)	3e-51	207	36%	UniProt GenBank	Two-component system sensor kinase	SSFG_01878	Streptomyces ghanaensis ATCC 14672
53	B5I2H0_9ACTO (B5I2H0)	4e-51	207	34%	UniProt GenBank	Two-component sensor kinase	SSEG_05926	Streptomyces sviceus ATCC 29083
54	D8HJ87_AMYMU (D8HJ87)	5e-51	206	37%	UniProt GenBank	Two-component system histidine kinase	AMED_8468	Amycolatopsis mediterranei (strain U-32)
55	D9XSI7_9ACTO (D9XSI7)	5e-51	206	35%	UniProt GenBank	Histidine kinase	SSRG_01459	Streptomyces griseoflavus Tu4000
56	Q82KJ9_STRAW (Q82KJ9)	1e-50	205	37%	UniProt GenBank	Putative two-component system sensor kinase	cutS SAV2404 SAV_2404	Streptomyces avermitilis
57	D1BK29_SANKS (D1BK29)	2e-50	204	37%	UniProt GenBank	Signal transduction histidine kinase	Sked_25340	Sanguibacter keddieii (strain ATCC 51767 / DSM 10542 / NCFB 3025 / ST-74)
58	F2RBX6_STRVP (F2RBX6)	2e-50	204	39%	UniProt GenBank	Two-component system sensor kinase	SVEN_3551	Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
59	D2B7S3_STRRD (D2B7S3)	3e-50	204	36%	UniProt GenBank	Signal transduction histidine kinase-like protein	Sros_0840	Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
60	D9WZ78_STRVR (D9WZ78)	3e-50	204	35%	UniProt GenBank	Two-component sensor kinase	SSQG_05899	Streptomyces viridochromogenes DSM 40736
61	B5G719_9ACTO (B5G719)	3e-50	204	36%	UniProt GenBank	Histidine kinase	SSBG_00291	Streptomyces sp. SPB74
62	D6K3J6_9ACTO (D6K3J6)	5e-50	203	37%	UniProt GenBank	Histidine kinase	SSTG_03887	Streptomyces sp. e14
63	D3CY99_9ACTO (D3CY99)	6e-50	202	38%	UniProt GenBank	Histidine kinase	FrEUN1fDRAFT_2519	Frankia sp. EUN1f
64	F3NNV9_9ACTO (F3NNV9)	2e-49	201	37%	UniProt GenBank	Putative two-component system sensor kinase	SGM_4823	Streptomyces griseoaurantiacus M045
65	D9UF67_9ACTO (D9UF67)	3e-49	200	35%	UniProt GenBank	Sensor protein cutS	SSLG_05121	Streptomyces sp. SPB78
66	B1VQX2_STRGG (B1VQX2)	4e-49	200	36%	UniProt GenBank	Putative two-component system sensor kinase	SGR_3794	Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
67	F2R1Z4_STRVP (F2R1Z4)	2e-48	197	39%	UniProt GenBank	Two-component sensor	SVEN_7375	Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
68	C9Z0G9_STRSW (C9Z0G9)	2e-48	197	35%	UniProt GenBank	Two-component sensor kinase	SCAB_24071	Streptomyces scabies (strain 87.22) Streptomyces scabiei
69	C8XG45_NAKMY (C8XG45)	3e-48	197	36%	UniProt GenBank	Histidine kinase	Namu_3749	Nakamurella multipartita (strain ATCC 700099 / DSM 44233 / JCM 9543 / Y-104) Microsphaera multipartita
70	D9VSJ1_9ACTO (D9VSJ1)	4e-48	197	39%	UniProt GenBank	Predicted protein	SSNG_04077	Streptomyces sp. C
71	D3Q1M5_STANL (D3Q1M5)	4e-48	197	36%	UniProt GenBank	Histidine kinase	Snas_0153	Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)
72	F4GZ29_CELFA (F4GZ29)	4e-47	194	35%	UniProt GenBank	Integral membrane sensor signal transduction histidine kinase	Celf_1889	Cellulomonas fimi (strain ATCC 484 / DSM 20113 / JCM 1341 / NBRC 15513 / NCIMB 8980 / NCTC 7547)
73	F3NLU6_9ACTO (F3NLU6)	4e-47	193	39%	UniProt GenBank	Putative two-component system sensor kinase	SGM_4201	Streptomyces griseoaurantiacus M045
74	D8HQ07_AMYMU (D8HQ07)	8e-47	192	37%	UniProt GenBank	Two-component system histidine kinase	AMED_4052	Amycolatopsis mediterranei (strain U-32)
75	F2UX76_ACTVI (F2UX76)	2e-46	191	34%	UniProt GenBank	Histidine kinase	HMPREF0059_01421	Actinomyces viscosus C505
76	C7QBH2_CATAD (C7QBH2)	2e-46	191	31%	UniProt GenBank	Histidine kinase	Caci_1628	Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
77	A8LB87_FRASN (A8LB87)	3e-46	191	34%	UniProt GenBank	Integral membrane sensor signal transduction histidine kinase	Franean1_0081	Frankia sp. (strain EAN1pec)
78	D6EP08_STRLI (D6EP08)	5e-46	190	35%	UniProt GenBank	Two-component sensor	SSPG_01865	Streptomyces lividans TK24
79	CUTS_STRLI (P0A4I8)	5e-46	190	35%	UniProt GenBank	Sensor protein CutS	cutS	Streptomyces lividans	2.7.13.3 niceE keggE
80	CUTS_STRCO (P0A4I7)	5e-46	190	35%	UniProt GenBank	Sensor protein CutS	cutS SCO5863 SC2E9.04	Streptomyces coelicolor	2.7.13.3 niceE keggE
81	E0KX54_STRVO (E0KX54)	2e-45	188	33%	UniProt GenBank	Integral membrane sensor signal transduction histidine kinase	StrviDRAFT_7232	Streptomyces violaceusniger Tu 4113
82	E3IZN7_FRASU (E3IZN7)	3e-45	187	38%	UniProt GenBank	Integral membrane sensor signal transduction histidine kinase	FraEuI1c_5971	Frankia sp. (strain EuI1c)
83	E8SBX2_MICSL (E8SBX2)	6e-45	186	34%	UniProt GenBank	Integral membrane sensor signal transduction histidine kinase	ML5_1876	Micromonospora sp. (strain L5)
84	D9SZP0_MICAI (D9SZP0)	6e-45	186	34%	UniProt GenBank	ATP-binding region ATPase domain protein	Micau_1617	Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
85	E7N6I9_9ACTO (E7N6I9)	2e-44	184	34%	UniProt GenBank	ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein	HMPREF9057_00392	Actinomyces sp. oral taxon 171 str. F0337
86	C7MYJ0_SACVD (C7MYJ0)	8e-43	179	35%	UniProt GenBank	Signal transduction histidine kinase	Svir_24130	Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
87	F2RIZ3_STRVP (F2RIZ3)	1e-41	175	34%	UniProt GenBank	Putative two-component system sensor kinase	SVEN_6833	Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
88	D9UXX0_9ACTO (D9UXX0)	1e-41	175	35%	UniProt GenBank	Two-component sensor	SSMG_02154	Streptomyces sp. AA4
89	D8HXX9_AMYMU (D8HXX9)	2e-41	174	37%	UniProt GenBank	Two-component system histidine kinase	AMED_2626	Amycolatopsis mediterranei (strain U-32)
90	D6XCM3_9ACTO (D6XCM3)	2e-41	174	34%	UniProt GenBank	Sensor histidine kinase	SSEG_10728	Streptomyces sviceus ATCC 29083
91	F3P7V6_9ACTO (F3P7V6)	3e-41	174	33%	UniProt GenBank	ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein	HMPREF9056_01123	Actinomyces sp. oral taxon 170 str. F0386
92	A4FAQ8_SACEN (A4FAQ8)	6e-41	173	39%	UniProt GenBank	Two-component sensor (Kinase)	cutS SACE_1818	Saccharopolyspora erythraea (strain NRRL 23338)	2.7.3.- niceE keggE
93	B5HLN8_9ACTO (B5HLN8)	8e-41	172	34%	UniProt GenBank	Two component sensor kinase	SSEG_08353	Streptomyces sviceus ATCC 29083
94	D8HLW1_AMYMU (D8HLW1)	1e-40	172	35%	UniProt GenBank	Two-component system histidine kinase	AMED_8142	Amycolatopsis mediterranei (strain U-32)
95	D7B818_NOCDD (D7B818)	1e-40	172	34%	UniProt GenBank	Integral membrane sensor signal transduction histidine kinase	Ndas_4943	Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) Actinomadura dassonvillei
96	D6ADL3_STRFL (D6ADL3)	2e-40	171	33%	UniProt GenBank	Sensory protein kinase	SSGG_04066	Streptomyces roseosporus NRRL 15998
97	E9UYS2_9ACTO (E9UYS2)	2e-40	171	33%	UniProt GenBank	Putative two-component system sensor kinase	NBCG_03943	Nocardioidaceae bacterium Broad-1
98	C0W8A9_9ACTO (C0W8A9)	3e-40	171	33%	UniProt GenBank	Histidine kinase	cutS HMPREF0058_2103	Actinomyces urogenitalis DSM 15434
99	A4X513_SALTO (A4X513)	5e-40	170	35%	UniProt GenBank	ATP-binding region, ATPase domain protein domain protein	Strop_1497	Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
100	E9V302_9ACTO (E9V302)	2e-39	168	32%	UniProt GenBank	Histidine kinase	NBCG_05454	Nocardioidaceae bacterium Broad-1

accession

alignment

Evalue

Score

Ident.

link

information

pubmed

Q7WZ69_9ACTO
(Q7WZ69)

0.0

830

100%

Product: Putative sensory kinase
Gene: dbv22
Organism: Nonomuraea sp. ATCC 39727

1uniprot[Pubmed] 12837387 [Medline] 22721464
The gene cluster for the biosynthesis of the glycopeptide antibiotic A40926 by nonomuraea species.(Chem. Biol.) [2003]

D7C2P2_STRBB
(D7C2P2)

9e-82

308

50%

Product: Histidine kinase
Gene: SBI_02804
Organism: Streptomyces bingchenggensis (strain BCW-1)

1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]

E2D2F1_9BACT
(E2D2F1)

1e-75

288

43%

Product: Histidine kinase
Gene
Organism: uncultured soil bacterium

1uniprot[Pubmed] 20577994
Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR.(Biopolymers) [2010]

Q47NJ6_THEFY
(Q47NJ6)

2e-63

247

38%

Product: ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal
Gene: Tfu_1940
Organism: Thermobifida fusca (strain YX)

1uniprot[Pubmed] 17209016
Genome sequence and analysis of the soil cellulolytic actinomycete Thermobifida fusca YX.(J. Bacteriol.) [2007]

E4NI79_KITSK
(E4NI79)

2e-62

244

39%

Product: Putative two-component system sensor kinase
Gene: cutS
KSE_54340
Organism: Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae

1uniprot[Pubmed] 21059706
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010]

D7C512_STRBB
(D7C512)

7e-62

242

43%

Product: Histidine kinase
Gene: SBI_05118
Organism: Streptomyces bingchenggensis (strain BCW-1)

1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]

C7PZZ7_CATAD
(C7PZZ7)

5e-61

239

38%

Product: Histidine kinase
Gene: Caci_6644
Organism: Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)

1uniprot
Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009]

B1VXN2_STRGG
(B1VXN2)

3e-60

237

37%

Product: Putative two-component system sensor kinase
Gene: SGR_1669
Organism: Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)

1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]

F4F149_VERMA
(F4F149)

4e-60

236

40%

Product: Histidine kinase
Gene: VAB18032_07925
Organism: Verrucosispora maris (strain AB-18-032)

1uniprot[Pubmed] 21551311
Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011]

D1AC04_THECD
(D1AC04)

9e-59

232

41%

Product: Histidine kinase
Gene: Tcur_1695
Organism: Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)

1uniprot
Complete genome sequence of Thermomonospora curvata type strain (B9).(Stand. Genomic Sci.) [2011]

F2R814_STRVP
(F2R814)

4e-58

230

36%

Product: Two-component sensor
Gene: SVEN_5537
Organism: Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)

1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]

Q2JA80_FRASC
(Q2JA80)

4e-58

230

40%

Product: Periplasmic sensor signal transduction histidine kinase
Gene: Francci3_2445
Organism: Frankia sp. (strain CcI3)

1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]

B5GUQ2_STRCL
(B5GUQ2)

3e-57

227

37%

Product: Sensor protein
Sensor protein cutS
Gene: SCLAV_4787
SSCG_03037
Organism: Streptomyces clavuligerus ATCC 27064

1uniprot[Pubmed] 20624727
The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]

D7CAW3_STRBB
(D7CAW3)

3e-57

227

36%

Product: Integral membrane sensor signal transduction histidine kinase
Gene: SBI_05560
Organism: Streptomyces bingchenggensis (strain BCW-1)

1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]

D2AZF0_STRRD
(D2AZF0)

6e-57

226

37%

Product: Integral membrane sensor signal transduction histidine kinase
Gene: Sros_0303
Organism: Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)

1uniprot
Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010]

D7B0R0_NOCDD
(D7B0R0)

1e-56

225

39%

Product: Integral membrane sensor signal transduction histidine kinase
Gene: Ndas_2884
Organism: Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei

1uniprot
Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010]

D7C8J9_STRBB
(D7C8J9)

2e-55

221

38%

Product: Putative two-component system sensor kinase
Gene: cutS
SBI_03267
Organism: Streptomyces bingchenggensis (strain BCW-1)

1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]

D3Q036_STANL
(D3Q036)

2e-54

218

35%

Product: Histidine kinase
Gene: Snas_5938
Organism: Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)

1uniprot
Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21T).(Stand. Genomic Sci.) [2009]

A8L3M1_FRASN
(A8L3M1)

5e-54

216

35%

Product: Integral membrane sensor signal transduction histidine kinase
Gene: Franean1_6947
Organism: Frankia sp. (strain EAN1pec)

1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]

D7B079_NOCDD
(D7B079)

1e-53

215

39%

Product: Integral membrane sensor signal transduction histidine kinase
Gene: Ndas_4783
Organism: Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei

1uniprot
Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010]

Q54293_STRHY
(Q54293)

2e-53

214

36%

Product: Sensory protein kinase
Gene: orfS
Organism: Streptomyces hygroscopicus

[pubmed all]
1uniprot[Pubmed] 7644502 [Medline] 95372374 The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895 Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896 Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]

D5SL45_STRCL
(D5SL45)

2e-53

214

41%

Product: Sensor protein
Gene: SCLAV_p1152
Organism: Streptomyces clavuligerus ATCC 27064

1uniprot
The sequence of a 1.8 Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]

D2AR60_STRRD
(D2AR60)

3e-52

211

37%

Product: Integral membrane sensor signal transduction histidine kinase
Gene: Sros_5650
Organism: Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)

1uniprot
Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010]

B5GU89_STRCL
(B5GU89)

3e-52

211

39%

Product: Sensor protein
Sensory protein kinase
Gene: SCLAV_3019
SSCG_02913
Organism: Streptomyces clavuligerus ATCC 27064

1uniprot[Pubmed] 20624727
The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]

C7Q499_CATAD
(C7Q499)

3e-52

210

38%

Product: Histidine kinase
Gene: Caci_1033
Organism: Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)

1uniprot
Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009]

D2B5H6_STRRD
(D2B5H6)

3e-52

210

35%

Product: Signal transduction histidine kinase-like protein
Gene: Sros_6772
Organism: Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)

1uniprot
Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010]

C6WAL1_ACTMD
(C6WAL1)

9e-52

209

38%

Product: Histidine kinase
Gene: Amir_1527
Organism: Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)

1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]

D8HJ87_AMYMU
(D8HJ87)

5e-51

206

37%

Product: Two-component system histidine kinase
Gene: AMED_8468
Organism: Amycolatopsis mediterranei (strain U-32)

1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]

Q82KJ9_STRAW
(Q82KJ9)

1e-50

205

37%

Product: Putative two-component system sensor kinase
Gene: cutS
SAV2404
SAV_2404
Organism: Streptomyces avermitilis

1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]

D1BK29_SANKS
(D1BK29)

2e-50

204

37%

Product: Signal transduction histidine kinase
Gene: Sked_25340
Organism: Sanguibacter keddieii (strain ATCC 51767 / DSM 10542 / NCFB 3025 / ST-74)

1uniprot
Complete genome sequence of Sanguibacter keddieii type strain (ST-74T).(Stand. Genomic Sci.) [2009]

F2RBX6_STRVP
(F2RBX6)

2e-50

204

39%

Product: Two-component system sensor kinase
Gene: SVEN_3551
Organism: Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)

1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]

D2B7S3_STRRD
(D2B7S3)

3e-50

204

36%

Product: Signal transduction histidine kinase-like protein
Gene: Sros_0840
Organism: Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)

1uniprot
Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010]

F3NNV9_9ACTO
(F3NNV9)

2e-49

201

37%

Product: Putative two-component system sensor kinase
Gene: SGM_4823
Organism: Streptomyces griseoaurantiacus M045

1uniprot[Pubmed] 21551298
Draft Genome Sequence of the Marine Bacterium Streptomyces griseoaurantiacus M045, Which Produces Novel Manumycin-Type Antibiotics with a pABA Core Component.(J. Bacteriol.) [2011]

B1VQX2_STRGG
(B1VQX2)

4e-49

200

36%

Product: Putative two-component system sensor kinase
Gene: SGR_3794
Organism: Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)

1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]

F2R1Z4_STRVP
(F2R1Z4)

2e-48

197

39%

Product: Two-component sensor
Gene: SVEN_7375
Organism: Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)

1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]

C9Z0G9_STRSW
(C9Z0G9)

2e-48

197

35%

Product: Two-component sensor kinase
Gene: SCAB_24071
Organism: Streptomyces scabies (strain 87.22)
Streptomyces scabiei

1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]

D3Q1M5_STANL
(D3Q1M5)

4e-48

197

36%

Product: Histidine kinase
Gene: Snas_0153
Organism: Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)

1uniprot
Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21T).(Stand. Genomic Sci.) [2009]

F3NLU6_9ACTO
(F3NLU6)

4e-47

193

39%

Product: Putative two-component system sensor kinase
Gene: SGM_4201
Organism: Streptomyces griseoaurantiacus M045

D8HQ07_AMYMU
(D8HQ07)

8e-47

192

37%

Product: Two-component system histidine kinase
Gene: AMED_4052
Organism: Amycolatopsis mediterranei (strain U-32)

1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]

C7QBH2_CATAD
(C7QBH2)

2e-46

191

31%

Product: Histidine kinase
Gene: Caci_1628
Organism: Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)

1uniprot
Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009]

A8LB87_FRASN
(A8LB87)

3e-46

191

34%

Product: Integral membrane sensor signal transduction histidine kinase
Gene: Franean1_0081
Organism: Frankia sp. (strain EAN1pec)

1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]

CUTS_STRLI
(P0A4I8)

5e-46

190

35%

Product: Sensor protein CutS
Gene: cutS
Organism: Streptomyces lividans

1uniprot[Pubmed] 1956295 [Medline] 92065815
A cloned ompR-like gene of Streptomyces lividans 66 suppresses defective melC1, a putative copper-transfer gene.(Mol. Microbiol.) [1991]

CUTS_STRCO
(P0A4I7)

5e-46

190

35%

Product: Sensor protein CutS
Gene: cutS
SCO5863
SC2E9.04
Organism: Streptomyces coelicolor

1uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]

C7MYJ0_SACVD
(C7MYJ0)

8e-43

179

35%

Product: Signal transduction histidine kinase
Gene: Svir_24130
Organism: Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)

1uniprot
Complete genome sequence of Saccharomonospora viridis type strain (P101T).(Stand. Genomic Sci.) [2009]

F2RIZ3_STRVP
(F2RIZ3)

1e-41

175

34%

Product: Putative two-component system sensor kinase
Gene: SVEN_6833
Organism: Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)

1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]

D8HXX9_AMYMU
(D8HXX9)

2e-41

174

37%

Product: Two-component system histidine kinase
Gene: AMED_2626
Organism: Amycolatopsis mediterranei (strain U-32)

1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]

A4FAQ8_SACEN
(A4FAQ8)

6e-41

173

39%

Product: Two-component sensor (Kinase)
Gene: cutS
SACE_1818
Organism: Saccharopolyspora erythraea (strain NRRL 23338)

1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]

D8HLW1_AMYMU
(D8HLW1)

1e-40

172

35%

Product: Two-component system histidine kinase
Gene: AMED_8142
Organism: Amycolatopsis mediterranei (strain U-32)

1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]

D7B818_NOCDD
(D7B818)

1e-40

172

34%

Product: Integral membrane sensor signal transduction histidine kinase
Gene: Ndas_4943
Organism: Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei

1uniprot
Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010]