Asco_00060 : CDS information

Location

Organism	Streptomyces hygroscopicus subsp. ascomyceticus
Strain	ATCC 14891 (=NBRC 13981)
Entry name	Ascomycin
Contig	AF235504
Start / Stop / Direction	6,808 / 8,052 / + [in whole cluster] 6,808 / 8,052 / + [in contig]
Location	6808..8052 [in whole cluster] 6808..8052 [in contig]
Type	CDS
Length	1,245 bp (414 aa)

Annotation

Category	5.4 hypothetical protein
Product	hypothetical protein
Product (GenBank)	FkbF
Gene
Gene (GenBank)	fkbF
EC number
Keyword
Note
Note (GenBank)	similar to Rhizobium trifolii MatC; dicarboxylate carrier
Reference	ACC Q9KIE8 PmId [10863099] The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units. (Gene. , 2000) comment FK520 gene clusterの報告。 fkbF: dicarboxylate carrier(?) fkbFは12TMSsのタンパク。最も近いhomologueはRhizobium trifoliiのputative dicarboxylate carrier protein。FK520合成は細胞膜を通したdicarboxylic acidの移動を要求しなそうなので、FkbFは他の機能を持っているのかもしれない。

Sequence

>hypothetical protein [FkbF]
MPNELTGVLILAAVFLLAGVRGLNMGLLALVATFLLGVVALDRTPDEVLAGFPASMFLVL
VAVTFLFGIARVNGTVDWLVRVAVRAVGARVGAVPWVLFGLAALLCATGAASPAAVAIVA
PISVAFAVRHRIDPLYAGLMAVNGAAAGSFAPSGILGGIVHSALEKNHLPVSGGLLFAGT
FAFNLAVAAVSWLVLGRRRLEPHDLDEDTDPTEGDPASRPGAEHVMTLTAMAALVLGTTV
LSLDTGFLALTLAALLALLFPRTSQQATKEIAWPVVLLVCGIVTYVALLQELGIVDSLGK
MIAAIGTPLLAALVICYVGGVVSAFASTTGILGALMPLSEPFLKSGAIGTTGMVMALAAA
ATVVDASPFSTNGALVVANAPERLRPGVYQGLLWWGAGVCALAPAAAWAAFVVA

>hypothetical protein [FkbF]
ATGCCGAATGAACTCACCGGAGTCCTGATCCTGGCCGCCGTGTTCCTGCTCGCCGGCGTA
CGGGGGCTGAACATGGGCCTGCTCGCGCTGGTCGCCACCTTTCTGCTCGGGGTGGTCGCA
CTCGACCGAACGCCGGACGAGGTGCTGGCGGGTTTCCCCGCGAGCATGTTCCTGGTGCTG
GTCGCCGTCACGTTCCTCTTCGGGATCGCCCGCGTCAACGGCACGGTGGACTGGCTGGTA
CGTGTCGCGGTGCGGGCGGTGGGGGCCCGGGTGGGAGCCGTCCCCTGGGTGCTCTTCGGC
CTGGCGGCACTGCTCTGCGCGACAGGCGCGGCCTCGCCCGCGGCGGTGGCGATCGTGGCG
CCGATCAGCGTCGCGTTCGCCGTCAGGCACCGCATCGATCCGCTGTACGCCGGACTGATG
GCGGTGAACGGGGCCGCAGCCGGCAGTTTCGCCCCCTCCGGGATCCTGGGCGGCATCGTC
CACTCGGCGCTGGAGAAGAACCATCTGCCCGTCAGCGGCGGGCTGCTCTTCGCAGGCACC
TTCGCCTTCAACCTGGCGGTCGCCGCGGTGTCATGGCTCGTCCTCGGGCGCAGGCGCCTC
GAACCACATGACCTGGACGAGGACACCGATCCCACGGAAGGGGACCCGGCTTCCCGCCCC
GGCGCGGAACACGTGATGACGCTGACCGCGATGGCCGCGCTGGTGCTGGGAACCACGGTC
CTCTCCCTGGACACCGGCTTCCTGGCCCTCACCTTGGCGGCGTTGCTGGCGCTGCTCTTC
CCGCGCACCTCCCAGCAGGCCACCAAGGAGATCGCCTGGCCCGTGGTGCTGCTGGTATGC
GGGATCGTGACCTACGTCGCCCTGCTCCAGGAGCTGGGCATCGTGGACTCCCTGGGGAAG
ATGATCGCGGCGATCGGCACCCCGCTGCTGGCCGCCCTGGTGATCTGCTACGTGGGCGGT
GTCGTCTCGGCCTTCGCCTCGACCACCGGGATCCTCGGTGCCCTGATGCCGCTGTCCGAG
CCGTTCCTGAAGTCCGGTGCCATCGGGACGACCGGCATGGTGATGGCCCTGGCGGCCGCG
GCGACCGTGGTGGACGCGAGTCCCTTCTCCACCAATGGTGCTCTGGTGGTGGCCAACGCT
CCCGAGCGGCTGCGGCCCGGCGTGTACCAGGGGTTGCTGTGGTGGGGCGCCGGGGTGTGC
GCACTGGCTCCCGCGGCCGCCTGGGCGGCCTTCGTGGTGGCGTGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR009827 Dicarboxylate carrier MatC N-terminal (Domain) PF07158 MatC_N
SignalP	Eukaryota Bacteria, Gram-negative
TMHMM	Transmembrane 11

Asco_00050 Asco_00070