Monen_00240 Monen_00240   Monen_00260 Monen_00260

Monen_00250 : CDS information

close this sectionLocation

Organism
StrainATCC 15413
Entry nameMonensin
Contig
Start / Stop / Direction88,708 / 77,447 / - [in whole cluster]
88,708 / 77,447 / - [in contig]
Locationcomplement(77447..88708) [in whole cluster]
complement(77447..88708) [in contig]
TypeCDS
Length11,262 bp (3,753 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category1.1 PKS
Productpolyketide synthase
Product (GenBank)monensin polyketide synthase modules 11 and 12
Gene
Gene (GenBank)monAVIII
EC number
Keyword
Note
Note (GenBank)
  • MonAVIII
Reference
ACC
PmId
[12940979] Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization. (Mol Microbiol. , 2003)
comment
monensin生合成 gene clusterの解析論文。

MonAVIII: Polyketide synthase
module11(KS, AT, KR, ACP),
module12(KS, AT, dh, er, KR, ACP)

module 12はmonensin PKSの最終moduleだがTE domainを含んでいない。
(MonCIIがpolyketide chain releaseを担うthioesterase)

close this sectionPKS/NRPS Module

11 methylmalonyl-CoA
12 methylmalonyl-CoA
KS32..408
AT563..882
KR1202..1381
ACP1485..1555
KS1581..1958
AT2119..2436
dh2485..2652
er
KR3275..3455
ACP3559..3629

close this sectionSequence

selected fasta
>polyketide synthase [monensin polyketide synthase modules 11 and 12]
MSNEEKLLDHLKWVTAELRQARQRLHDKESTEPVAIVGMACRYPGGARSAEDLWELVRDG
GDAVAGFPDDRGWDLESLYHPDPEHPATSYVRDGAFLYDAGHFDAEFFGISPREATAMDP
QQRLLLETAWEAIEHAGMNPHALKGSDTGVFTGVSAHDYLTLISQTASDVEGYIGTGNLG
SVVSGRISYTVGLEGPAVTVDTACSSSLVAIHLASQALRQGECSLALAGGSTVMATPGSF
TEFSRQRGLAPDGRCKPFAAAADGTGWGEGAGVVALELLSEARRRGHKVLAVIRGSATNQ
DGTSNGLAAPNGPSQERVIRAALANARLSAEDIDAVEAHGTGTTLGDPIEAQALIATYGQ
GRPEDRPLWLGSVKSNIGHTQAAAGVAGVIKMVMAMRNGLLPTSLHIDAPSPHVQWEQGS
VRLLSEPVDWPAERTRRAGISAFGISGTNAHLILEEAPPEEDAPGPVAAEPGGVVPWVVS
GRTPDALREQARRLGEFAAGLADASVSEVGWSLATTRALFDQRAVVVGRDLAQAGASLEA
LAAGEASADVVAGVAGDVGPGPVLVFPGQGSQWVGMGAQLLDESPVFAARIAECEQALSA
HVDWSLSDVLRGDGSELSRVEVVQPVLWAVMVSLAAVWADYGITPAAVIGHSQGEMAAAC
VAGALSLEDAARIVAVRSDALRQLQGHGDMASLSTGAEQAAELIGDRPGVVVAAVNGPSS
TVISGPPEHVAAVVADAEAQGLRARVIDVRYASHGPQIDQLHDLLTDRLADIQPTTTDVA
FYSTVTAERLDDTTALDTAYWVTNLRQPVRFADTIEALLADGYRLFIEASPHPVLNLGIQ
ETIEQQAGAAGTAVTIPTLRRDHGDTTQLTRAAAHAFTAGAPVDWRRWFPADPTPRTVDL
PTYAFQHKHYWVEPPAAVAAVGGGHDPVEARVWQAIEDLDIDALAGSLEIEGQAESVGAL
ESALPVLSAWRRRHREQSTVDSWRYQVTWKHLPDVPAPELSGAWLLLVPAAHADHPAVLA
TAQTLTAHGGEVRRHVVDARAMERTELAQELRVLMDGAAFAGVVNLLALDEEPHPEHSAV
PAGLAATTALVQALADNGADIAVRTLTQGAVSTSAGDALTHPVQAQVWGLGRVAALEYPR
LWGGLVDLPARIDHQTLARLAAALVPQDEDQISIRPSGVHARRLAHAPANTVGSGLGWRP
DGTTLITGGTGGIGAVLARWLARAGAPHLLLTSRRGPDAPGAQELAAELTELGAAVTVTA
CDVGDREQVRRLIDDVPAEHPLTAVIHAAGVPNYIGLGDVSGAELDEVLRPKALAAHHLH
ELTRELPLSAFVMFSSGAGVWGSGQQGAYGAANHFLDALAEHRRAEGLPATSIAWGPWAE
AGMAADQAALTFFSRFGLHPLSPELCVKALQQALDAGETTLTVANFDWAQFTSTFTAQRP
SPLLADLPENRRASAPAAQQEDATEASSLQQELTEAKPAQQRQLLLQHVRSQAAATLGHS
DVDAVPATKPFQELGFDSLTAVELRNRLNKSTGLTLPTTVVFDHPTPDALTDVLRAELSG
DAAASADPVRAAGASRGAADDEPIAIVGMACRYPGDVRSAEELWDLVAAGKDAMGAFPDD
RGWDLETLYDPDPESRGTSYVREGGFLYDAGDFDAGFFGISPREAVAMDPQQRLLLETAW
EAIERAGLDRETLKGSDAGVFTGLTIFDYLALVGEQPTEVEGYIGTGNLGCVASGRVSYV
LGLEGPAMTIDTGCSSSLVAIHQAAHALRQGECSLALAGGATVMATPGSFVEFSLQRGLA
KDGRCKPFAAAADGTGWAEGVGLVVLERLSEARRNGHNVLAVIRGSAINQDGTSNGLTAP
NGQAQQRVIRQALANARLSAEDVDAVEAHGTGTMLGDPIEASALVATYGKERPADRPLWL
GSIKSNIGHAQASAGVAGVIKMVMALRNEQLPASLHIDAPTPHVDWDGSGVRLLSEPVSW
PRGERPRRAGVSAFGISGTNAHLILEQAPDAPEPVTAPAEDAAAPAGVVPWVVSARGEEA
LRAQARLLADRATADPRLASPLDVGWSLVKTRSVFENRAVVVGKDRQTLLAGLRSLAAGE
PSPDVVEGAVQGASGAGPVLVFPGQGSQWVGMGAQLLDESPVFAARIAECERALSAHVDW
SLSAVLRGDGSELSRVEVVQPVLWAVMVSLASVWADYGITPAAVIGHSQGEMAAACVAGA
LSLEDAARIVAVRSDALRQLMGQGDMASLGAGSEQVAELIGDRPGVCVAAVNGPSSTVIS
GPPEHVAAVVADAEARGLRARVIDVGYASHGPQIDQLHDLLTERLADIRPTTTDVAFYST
VTAERLDDTTTLDTDYWVTNLRQPVRFADTIEALLADGYRLFIEASPHPVLNLGMEETIE
RADMPATVVPTLRRDHGDAAQLTRAAAQAFGAGAEVDWTGWFPAVPLPRVVDLPTYAFQR
ERFWLEGRRGLAGDPAGLGLASAGHPLLGAAVELADGGSHLLTGRISPRDQAWLAEHRVM
DTVLLPGSAFVELALQAAVRAGCAELAELTLHTPLAFGDEGAGAVDVQVVVGSVAEDGRR
PVTVHSRPTGEGEEAVWTRHAAGVVAPPGPDAGDASFGGTWPPPGATPVGEQDPYGELAS
YGYDFGPGSQGLVSAWRLGDDLFAEVALPEAESGRADRYQVHPVLLDATLHALILDAVTS
SADTDQVLLPFSWSGLRVHAPGAEKLRVRIARTAPDQLALTAVDGGGGGEPVLTLESLTV
RPVAAHQIAGARAADRDALFRLVWMEVAARAEETGGGAPRAAVLAPVESGPMGGTSAGAL
ADALSDALAAGPVWDTFGALRDGVAAGGEAPDVVLAVCAAPGAGAGAVADADGRGGDPAG
YARLATVSLLSLLKEWVDDPAFAATRLVVVTRGAVAARPGETAGDLAGASLWGLVRSAQA
ENPGRLTLLDVDGLESSPATLTGVLASGEPELALRDGRAYVPRLVRDDASVRLVPPVGSL
TWRLARCQEAGGGQQLSLVDAPEAGRALEPHEVRVAVRAAAPGPLTAGQVEGAGVVTEVG
GEVGSVAVGDRVMGLFDAVGPVAVTDAALLMPVPAGWSWAQAAGSLGAYVSAYHVLADVV
APRGGETLLVGEETGSVGRAVLRLALAGRWRVEAVDGASTADDSGAERAADVTLRHEGAL
VVHRAGGRPDEGQAVVPPEPGRVREILAELTELTELAEITESAEPGLPAERGDSRALTPL
DITVWDIRQAPAAMAAPPSAGTTVFSLPPAFDPEGTVLVTGGTGALGSLTARHLVERYGA
RHLLLSSRRGADAPGALELAADLSALGARVTFAACDPGDRDEAAALLAAVPSDHPLTAVF
HCAGTVNDAVVQNLTAEQVEEVMRVKADAAWHLHELTRDADLSAFVLYSSVAGLLGGPGQ
GSYTAANAFLDALARHRHDGGAAATSLAWGYWELASGMSGRLTDADRARHARAGVVGLGA
DEGLALLDAAWAGGLPLYAPVRLDLARMRRQAQSHPAPALLRDLVRGGSKSGGGAVSAGA
AALLKSLGAMSDPEREEALLDLVCTHIAAVLGYDAATPVNATQGLRELGFDSLTAVELRN
RLSAATGLKLPATFVFDHPNPAELAAQLRQELAPRAADPLADVLAEFERIEDSLLSVSSK
DGSARAELAGRLRATLARLDAPQDTAGEVAVATRTRIQDASADEIFAFIDRDLGRDGASG
QGNGQPTGQGNGHGNGNGNGNGNGHGQAVEGQR
selected fasta
>polyketide synthase [monensin polyketide synthase modules 11 and 12]
ATGTCGAACGAGGAGAAGCTTCTCGATCACCTCAAGTGGGTCACCGCGGAGCTGCGCCAG
GCCCGGCAACGGCTCCACGACAAGGAATCGACCGAGCCGGTCGCCATCGTCGGCATGGCC
TGCCGCTACCCGGGCGGCGCCCGGTCGGCGGAGGACCTCTGGGAACTCGTGCGCGACGGG
GGTGACGCGGTCGCGGGGTTCCCCGACGACCGGGGCTGGGACCTGGAGTCGCTGTATCAC
CCGGATCCGGAGCATCCGGCCACCAGCTATGTGCGGGACGGCGCCTTCCTGTACGACGCC
GGCCATTTCGACGCCGAGTTCTTCGGCATCAGCCCGCGCGAGGCCACGGCGATGGATCCG
CAGCAGCGGCTGCTCCTGGAGACCGCGTGGGAGGCGATCGAGCACGCGGGCATGAACCCG
CACGCGCTGAAGGGCAGCGACACCGGCGTCTTCACCGGAGTGAGCGCCCACGACTACCTG
ACGCTGATCAGCCAGACGGCCAGCGACGTCGAGGGGTACATCGGCACCGGCAACCTCGGC
AGTGTGGTGTCGGGCCGGATCTCCTACACGGTGGGGCTCGAAGGTCCCGCGGTCACCGTC
GACACGGCGTGCTCGTCGTCCCTGGTGGCGATCCATCTGGCAAGTCAGGCGCTGCGGCAG
GGCGAGTGCTCGCTCGCGCTGGCGGGCGGTTCGACGGTGATGGCGACGCCGGGTTCGTTC
ACCGAGTTCTCCCGGCAGCGGGGGCTCGCGCCCGACGGGCGGTGCAAGCCGTTCGCGGCC
GCCGCCGACGGCACCGGCTGGGGCGAGGGCGCCGGGGTGGTGGCGCTGGAGCTGCTCTCC
GAAGCGCGGCGCCGCGGCCACAAGGTCCTTGCGGTGATACGGGGTTCGGCCACCAACCAG
GACGGTACGAGCAACGGGCTCGCCGCCCCCAACGGCCCCTCCCAGGAACGCGTCATCCGC
GCCGCCCTCGCCAACGCCCGCCTCTCCGCCGAGGACATCGACGCCGTAGAGGCGCACGGC
ACCGGCACCACGCTCGGCGACCCCATCGAGGCGCAGGCCCTGATCGCCACGTACGGCCAG
GGGCGCCCGGAGGACCGTCCGCTCTGGCTCGGCTCGGTGAAATCCAACATCGGCCACACG
CAGGCCGCCGCCGGTGTCGCGGGCGTCATCAAGATGGTCATGGCGATGCGCAACGGTCTC
CTCCCGACCTCCCTGCACATCGACGCCCCGTCACCGCACGTCCAGTGGGAACAGGGCAGC
GTACGACTGCTCTCCGAGCCCGTGGACTGGCCGGCGGAGCGCACGCGGCGGGCAGGCATC
TCGGCGTTCGGGATCTCCGGGACGAACGCGCACCTGATTCTGGAGGAGGCGCCGCCGGAA
GAGGACGCGCCGGGCCCCGTGGCGGCTGAGCCGGGTGGGGTCGTGCCGTGGGTGGTGTCC
GGGCGGACGCCGGACGCGTTGCGTGAACAGGCGCGGCGGCTGGGCGAGTTCGCGGCCGGG
CTGGCGGATGCGTCGGTCTCCGAGGTGGGCTGGTCGCTGGCCACGACACGCGCGTTGTTC
GATCAGCGGGCCGTGGTCGTGGGGCGGGACTTGGCTCAGGCTGGTGCCAGCCTGGAGGCA
TTGGCCGCGGGTGAGGCGTCGGCGGATGTGGTGGCCGGGGTGGCCGGTGATGTGGGTCCT
GGGCCGGTGTTGGTGTTTCCGGGGCAGGGGTCGCAGTGGGTGGGCATGGGCGCCCAGCTC
CTTGACGAGTCGCCCGTCTTCGCGGCGCGGATCGCGGAGTGTGAGCAGGCGCTGTCGGCG
CATGTGGACTGGTCGCTGAGTGATGTCTTGCGCGGGGACGGGAGCGAGCTGTCCCGGGTC
GAGGTCGTGCAGCCCGTGCTGTGGGCGGTGATGGTCTCGCTGGCTGCGGTGTGGGCCGAT
TACGGCATCACCCCGGCTGCCGTCATCGGGCACTCGCAGGGCGAGATGGCTGCCGCGTGT
GTGGCGGGGGCACTGTCACTGGAGGATGCGGCACGGATCGTAGCCGTACGCAGCGACGCG
CTTCGTCAGCTGCAAGGGCACGGCGACATGGCCTCGCTCAGCACCGGTGCCGAGCAGGCC
GCAGAGCTGATCGGCGACCGGCCGGGCGTAGTCGTCGCGGCCGTCAACGGACCGTCGTCG
ACCGTGATTTCGGGCCCGCCGGAGCATGTGGCAGCCGTCGTCGCCGATGCGGAGGCGCAG
GGACTCAGGGCCCGCGTCATCGACGTCAGGTACGCCTCCCACGGTCCCCAGATCGACCAG
CTCCACGACCTCCTCACCGACCGGCTCGCCGACATCCAGCCGACCACCACCGACGTGGCG
TTCTACTCGACGGTCACCGCAGAGCGCCTCGACGACACCACCGCCCTAGACACCGCCTAC
TGGGTCACCAACCTCCGCCAGCCCGTCCGCTTCGCCGACACCATCGAAGCGCTGCTGGCC
GACGGCTACCGCCTGTTCATCGAGGCCAGCCCCCACCCCGTCCTCAACCTCGGCATCCAG
GAGACCATCGAGCAGCAGGCCGGTGCTGCGGGGACGGCCGTCACCATCCCCACCCTGCGT
CGCGACCACGGTGACACCACCCAGCTCACCCGCGCGGCCGCCCACGCCTTCACCGCCGGC
GCCCCCGTCGACTGGCGGCGCTGGTTCCCGGCCGACCCCACCCCCCGTACCGTCGACCTC
CCCACCTACGCCTTCCAGCACAAGCACTACTGGGTGGAGCCGCCCGCGGCGGTCGCAGCC
GTGGGTGGTGGGCACGATCCGGTCGAGGCCCGGGTGTGGCAGGCGATCGAGGACCTGGAC
ATCGACGCCCTCGCCGGCAGTCTGGAGATCGAGGGGCAGGCGGAGAGCGTCGGAGCGCTG
GAGTCCGCGCTGCCCGTCCTCTCGGCCTGGCGGCGTCGGCACCGCGAGCAGTCCACCGTC
GACTCCTGGCGTTATCAGGTCACTTGGAAGCATCTGCCCGACGTGCCGGCGCCGGAGCTC
AGCGGGGCCTGGCTGCTGCTCGTGCCCGCCGCGCACGCCGACCACCCGGCCGTCCTCGCG
ACCGCGCAGACGCTGACCGCCCATGGTGGCGAGGTGCGACGCCACGTGGTCGACGCACGT
GCCATGGAGCGTACGGAGTTGGCGCAGGAGCTGCGTGTCCTGATGGACGGGGCCGCGTTT
GCCGGAGTCGTCAATCTGCTGGCCCTGGACGAGGAGCCGCATCCCGAGCACTCGGCCGTG
CCCGCCGGACTCGCCGCGACGACCGCTCTCGTCCAGGCCCTCGCGGACAACGGCGCCGAC
ATCGCCGTACGCACTCTCACGCAGGGGGCTGTTTCCACGAGCGCCGGCGACGCCCTCACC
CACCCGGTGCAGGCTCAGGTGTGGGGGCTGGGGCGCGTCGCTGCGCTGGAGTATCCGCGG
CTGTGGGGCGGGCTGGTCGATCTGCCCGCTCGTATCGACCATCAGACGCTGGCCCGGCTG
GCCGCCGCGCTGGTTCCGCAGGACGAGGACCAGATCTCCATCCGGCCGTCCGGCGTCCAT
GCCCGTCGCCTTGCACACGCGCCCGCCAACACGGTCGGCAGCGGGCTTGGTTGGCGGCCC
GACGGCACCACTCTCATCACCGGCGGGACCGGCGGCATCGGCGCCGTCCTCGCGCGGTGG
CTCGCCCGTGCGGGCGCCCCGCACCTCCTCCTGACCAGCCGCCGCGGCCCCGACGCCCCG
GGAGCACAGGAACTCGCCGCGGAACTGACGGAGTTGGGGGCCGCCGTCACCGTCACCGCC
TGCGACGTCGGCGACCGCGAGCAGGTGCGACGCCTCATCGACGATGTCCCCGCCGAGCAC
CCGCTGACCGCCGTCATCCACGCGGCCGGCGTGCCGAACTACATCGGTCTCGGCGACGTG
TCGGGTGCCGAGCTGGACGAGGTGCTGCGTCCGAAGGCGCTCGCCGCTCACCATCTGCAT
GAACTGACCCGGGAGTTGCCGCTCTCGGCGTTCGTGATGTTCTCGTCGGGCGCAGGCGTG
TGGGGCAGTGGCCAGCAGGGCGCCTATGGTGCGGCCAACCACTTCCTCGACGCCCTCGCC
GAGCACCGCCGCGCCGAGGGCCTGCCCGCCACCTCCATCGCCTGGGGGCCCTGGGCCGAG
GCGGGCATGGCGGCGGACCAGGCCGCGTTGACGTTCTTCAGCCGCTTCGGCCTGCACCCG
CTCAGCCCGGAGCTGTGCGTCAAGGCGCTGCAGCAGGCCCTGGACGCGGGTGAGACGACG
CTGACCGTGGCGAACTTCGACTGGGCGCAGTTCACGTCGACGTTCACCGCGCAGCGGCCC
AGCCCGCTCCTCGCCGATCTGCCCGAGAACCGGCGGGCCAGCGCACCCGCGGCACAGCAG
GAAGACGCCACGGAGGCATCGTCGCTCCAGCAGGAGCTGACGGAGGCGAAGCCGGCGCAG
CAGCGGCAGTTGCTGCTGCAGCACGTGCGCTCCCAGGCGGCGGCCACGCTGGGGCACTCG
GACGTCGACGCGGTGCCCGCCACCAAGCCGTTCCAGGAGCTGGGCTTCGACTCGCTGACC
GCGGTGGAGCTGCGCAACAGGCTGAACAAGAGCACCGGCCTGACACTGCCGACCACGGTC
GTCTTCGACCACCCCACCCCCGACGCGCTCACCGACGTCCTGCGGGCCGAGCTGTCCGGT
GACGCGGCGGCCTCCGCCGACCCGGTGCGGGCGGCCGGGGCCTCCAGGGGCGCCGCCGAC
GACGAGCCGATCGCGATCGTCGGCATGGCCTGCCGCTATCCGGGCGACGTCCGCTCCGCC
GAGGAGCTGTGGGATCTGGTCGCGGCCGGCAAGGACGCCATGGGGGCCTTCCCCGACGAC
CGGGGCTGGGACCTGGAGACGCTGTACGACCCGGACCCGGAGAGCCGCGGCACCAGCTAT
GTGCGCGAAGGCGGGTTCCTCTACGACGCGGGCGACTTCGACGCCGGATTCTTCGGCATC
AGCCCCCGCGAGGCCGTCGCGATGGACCCGCAGCAGCGGCTGCTCCTGGAGACCGCGTGG
GAGGCGATCGAACGCGCGGGCCTCGACCGGGAGACCCTCAAGGGCAGCGACGCCGGGGTG
TTCACGGGCCTGACCATCTTCGACTACCTCGCGCTCGTCGGTGAACAGCCCACCGAGGTC
GAGGGCTACATCGGCACCGGCAACCTCGGCTGTGTCGCCTCCGGCAGGGTGTCGTACGTA
CTCGGCCTAGAAGGCCCCGCCATGACGATCGACACCGGCTGCTCTTCGTCCCTGGTGGCG
ATCCACCAGGCGGCGCACGCGCTGCGCCAGGGCGAGTGCTCGCTCGCTCTCGCGGGCGGC
GCGACGGTGATGGCCACGCCGGGCTCGTTCGTCGAGTTCTCGCTGCAGCGCGGGCTCGCC
AAGGACGGCCGGTGCAAGCCGTTCGCGGCCGCCGCCGACGGCACCGGCTGGGCCGAGGGA
GTCGGCCTGGTCGTACTCGAACGGCTCTCGGAGGCCCGGCGCAACGGCCACAACGTCCTG
GCGGTGATCCGGGGTTCGGCCATCAACCAGGACGGCACGAGCAACGGGCTCACGGCACCC
AACGGGCAGGCGCAGCAGCGGGTGATCCGGCAGGCACTCGCCAACGCGCGGCTCTCCGCC
GAGGACGTCGACGCGGTGGAGGCGCACGGCACCGGCACCATGCTGGGCGACCCCATCGAA
GCCAGCGCGCTCGTCGCCACCTACGGCAAGGAGCGGCCCGCGGACCGGCCGCTGTGGCTC
GGCTCGATCAAGTCGAACATCGGGCACGCGCAGGCGTCGGCCGGTGTCGCCGGTGTGATC
AAGATGGTCATGGCGCTGCGCAACGAACAGCTGCCCGCCTCCCTGCACATCGACGCGCCC
ACGCCGCACGTGGACTGGGACGGCAGTGGCGTCCGCCTGCTGTCCGAACCGGTCTCCTGG
CCGCGCGGCGAACGCCCGCGCCGCGCCGGGGTGTCCGCCTTCGGCATCTCCGGCACCAAC
GCGCACCTCATCCTGGAACAGGCCCCGGACGCGCCGGAGCCCGTGACCGCTCCGGCGGAG
GACGCCGCGGCGCCGGCCGGAGTGGTGCCCTGGGTGGTGTCGGCGCGCGGCGAGGAGGCG
CTGCGGGCCCAGGCCCGCCTGCTGGCCGACCGCGCCACCGCCGACCCGCGGCTCGCGTCG
CCGCTGGACGTGGGCTGGTCCCTGGTCAAGACCCGGTCGGTGTTCGAGAACCGAGCCGTC
GTCGTGGGCAAGGACCGCCAGACTCTCCTCGCCGGGCTACGGTCCCTGGCGGCGGGCGAG
CCGTCACCGGACGTCGTCGAGGGCGCCGTACAGGGCGCCTCCGGCGCGGGTCCGGTGTTG
GTGTTTCCGGGGCAGGGGTCGCAGTGGGTGGGCATGGGTGCCCAGCTCCTTGACGAGTCC
CCCGTCTTCGCGGCGCGGATCGCGGAGTGTGAGCGGGCCCTGTCGGCGCATGTGGACTGG
TCGCTGAGTGCGGTGTTGCGCGGGGACGGGAGTGAGCTGTCCCGGGTCGAGGTCGTGCAG
CCCGTGTTGTGGGCGGTGATGGTCTCGCTGGCTTCGGTGTGGGCCGATTACGGCATCACC
CCGGCTGCCGTCATCGGGCACTCGCAGGGCGAGATGGCCGCCGCGTGTGTGGCGGGGGCA
CTGTCACTGGAGGATGCGGCGCGGATCGTGGCCGTACGCAGTGACGCGCTCCGTCAGCTC
ATGGGGCAGGGCGACATGGCGTCGTTGGGGGCCGGCTCGGAGCAGGTTGCTGAGCTCATC
GGCGACCGGCCCGGCGTGTGTGTCGCTGCCGTCAACGGGCCCTCCTCTACGGTCATTTCA
GGGCCGCCGGAGCATGTGGCAGCCGTGGTCGCGGATGCGGAGGCGCGAGGCCTGCGCGCC
CGCGTCATCGACGTCGGATACGCCTCCCACGGCCCCCAGATCGACCAGCTCCACGACCTC
CTCACCGAGCGCCTGGCCGACATCCGGCCCACGACCACGGACGTCGCCTTCTACTCCACG
GTCACCGCCGAACGCCTCGACGACACCACCACCCTCGACACGGATTACTGGGTCACCAAC
CTCCGCCAGCCCGTCCGCTTCGCCGACACCATCGAAGCGCTGCTGGCCGACGGCTACCGC
CTGTTCATCGAGGCCAGCCCCCACCCCGTCCTCAACCTCGGCATGGAGGAGACCATCGAG
CGGGCCGACATGCCCGCCACCGTCGTGCCCACCCTGCGCCGCGACCACGGCGACGCCGCG
CAGCTCACCCGCGCGGCCGCCCAGGCCTTCGGCGCGGGGGCGGAGGTCGACTGGACGGGC
TGGTTCCCGGCCGTGCCGCTGCCTCGGGTGGTGGATCTGCCGACGTACGCCTTCCAGCGG
GAGCGGTTCTGGCTGGAGGGGCGCAGGGGGCTCGCCGGGGACCCGGCGGGGCTCGGGCTC
GCGTCCGCGGGGCATCCGCTGCTCGGAGCCGCCGTGGAACTCGCGGACGGCGGCAGTCAC
CTGCTGACCGGCCGGATCTCTCCGCGGGACCAGGCGTGGCTGGCCGAGCACCGGGTCATG
GACACGGTGCTGCTGCCCGGTTCGGCGTTCGTGGAGCTCGCGCTGCAGGCCGCGGTGCGG
GCCGGCTGCGCGGAGTTGGCGGAGCTGACGCTGCACACTCCGCTCGCCTTCGGGGACGAG
GGTGCGGGCGCGGTCGACGTGCAGGTGGTGGTCGGTTCCGTGGCCGAGGACGGGCGGCGT
CCCGTGACCGTCCATTCGCGGCCCACGGGTGAGGGCGAGGAGGCCGTGTGGACCCGGCAT
GCCGCGGGCGTGGTCGCTCCCCCGGGGCCCGACGCCGGGGACGCCTCGTTCGGCGGGACG
TGGCCGCCCCCGGGCGCCACACCGGTCGGCGAGCAGGATCCGTACGGGGAACTCGCTTCG
TACGGCTATGACTTCGGGCCCGGCTCACAGGGACTGGTGAGCGCGTGGCGGCTCGGGGAC
GACCTTTTCGCCGAGGTGGCGCTGCCCGAGGCGGAGAGCGGCAGGGCCGACCGCTACCAG
GTGCACCCGGTGTTGCTCGACGCCACGCTGCACGCGCTGATCCTGGACGCGGTCACGTCG
TCCGCCGACACCGACCAAGTGCTGCTGCCGTTCTCCTGGAGCGGGTTGCGGGTGCACGCG
CCGGGCGCTGAGAAGTTGCGGGTACGTATCGCACGCACCGCGCCCGACCAGCTGGCCCTC
ACGGCCGTGGACGGGGGCGGAGGCGGGGAGCCGGTTCTCACGCTGGAGTCGCTCACGGTA
CGGCCGGTGGCCGCCCACCAGATCGCGGGCGCCCGTGCGGCGGACCGTGACGCGCTGTTC
CGGCTCGTGTGGATGGAGGTCGCCGCGCGGGCCGAGGAGACGGGCGGCGGCGCCCCGCGT
GCCGCGGTCCTCGCGCCGGTCGAGAGTGGCCCGATGGGCGGTACGTCGGCCGGTGCGCTG
GCCGACGCCTTGTCCGATGCGCTGGCCGCCGGCCCCGTGTGGGACACGTTCGGTGCGCTC
CGGGACGGAGTGGCGGCTGGGGGCGAAGCGCCCGATGTCGTGCTCGCCGTGTGCGCCGCG
CCCGGCGCAGGTGCCGGGGCCGTTGCGGATGCCGATGGCAGGGGCGGCGACCCGGCCGGG
TACGCGCGGCTGGCCACCGTGTCCCTTCTGTCGCTGCTCAAGGAGTGGGTGGACGACCCG
GCGTTCGCGGCGACCCGTCTCGTCGTCGTCACCCGAGGCGCGGTCGCCGCGCGGCCGGGT
GAGACCGCCGGTGATCTGGCGGGCGCGTCGCTGTGGGGTCTGGTGCGCAGCGCGCAGGCC
GAGAATCCCGGTCGCCTCACGCTGCTCGACGTGGACGGACTGGAGTCTTCTCCGGCCACG
CTGACCGGCGTACTGGCCTCCGGCGAACCGGAATTGGCGCTGCGTGACGGGCGCGCCTAC
GTGCCACGGCTCGTGCGCGACGACGCGTCGGTGCGGCTGGTGCCGCCGGTCGGATCGCTC
ACGTGGCGGCTGGCTCGGTGCCAAGAGGCGGGCGGCGGACAGCAGTTGTCCCTTGTCGAC
GCTCCCGAGGCCGGACGGGCGCTGGAGCCGCACGAGGTGCGGGTGGCGGTGCGGGCCGCG
GCGCCGGGGCCGCTCACGGCGGGCCAGGTCGAGGGTGCCGGTGTGGTGACGGAAGTCGGC
GGCGAGGTCGGTTCGGTGGCCGTGGGCGACCGGGTGATGGGGTTGTTCGACGCGGTGGGC
CCGGTGGCCGTCACCGATGCCGCGCTGCTTATGCCGGTTCCGGCGGGCTGGAGTTGGGCG
CAGGCGGCCGGGTCCTTGGGGGCCTATGTGTCCGCGTATCACGTGCTGGCGGATGTCGTG
GCGCCGCGCGGCGGCGAGACTCTGCTCGTCGGGGAGGAAACCGGTTCCGTCGGCCGTGCC
GTGCTGCGTCTTGCTCTTGCCGGGCGGTGGCGGGTCGAGGCCGTGGACGGTGCGTCGACG
GCGGATGATTCGGGCGCCGAGCGCGCGGCCGACGTCACCCTCCGCCACGAGGGGGCCCTG
GTGGTCCACCGTGCGGGCGGTCGTCCGGACGAGGGACAGGCTGTCGTGCCGCCCGAGCCC
GGGCGCGTACGGGAAATCCTCGCGGAGCTGACCGAGCTGACCGAGCTTGCCGAGATCACG
GAGTCGGCGGAGCCCGGGCTGCCCGCGGAACGGGGTGACAGCCGTGCTCTGACGCCGCTC
GACATCACCGTGTGGGACATCCGGCAGGCGCCCGCCGCGATGGCGGCCCCGCCCTCGGCG
GGCACGACCGTGTTCTCGCTGCCTCCCGCCTTCGACCCCGAGGGCACCGTGCTGGTCACC
GGCGGCACCGGAGCACTCGGCTCGCTGACGGCCCGTCACCTGGTGGAACGGTACGGAGCC
AGGCACCTGTTGCTGTCCAGCAGGCGGGGAGCCGACGCGCCGGGCGCACTCGAACTGGCC
GCCGACCTCTCCGCGCTCGGCGCGCGAGTCACCTTCGCCGCGTGCGACCCGGGCGACCGG
GACGAAGCCGCCGCCCTCCTCGCGGCGGTGCCCTCGGACCACCCGCTGACCGCCGTCTTC
CACTGCGCGGGCACCGTGAACGACGCCGTGGTGCAGAACCTCACGGCCGAGCAGGTCGAG
GAGGTGATGCGCGTGAAGGCGGACGCCGCGTGGCACCTGCACGAGCTGACGCGGGACGCG
GACCTGTCCGCGTTCGTCCTGTACTCCTCGGTCGCCGGGCTGCTCGGCGGCCCCGGCCAG
GGCAGCTACACGGCCGCCAACGCCTTCTTGGACGCGCTGGCCCGGCACCGGCACGACGGC
GGTGCGGCGGCGACCTCCCTGGCGTGGGGCTACTGGGAGCTGGCGAGCGGCATGTCGGGA
CGGCTCACCGACGCCGACCGGGCGCGCCATGCCCGCGCCGGCGTGGTCGGGCTCGGCGCC
GACGAGGGACTCGCCCTCCTCGACGCGGCGTGGGCCGGCGGACTGCCCCTGTACGCGCCG
GTCCGTCTGGACCTGGCCCGGATGCGCCGGCAGGCCCAGAGCCACCCCGCACCGGCGCTG
CTGCGCGACCTGGTGCGCGGGGGGAGCAAGAGCGGCGGCGGTGCCGTGTCGGCGGGGGCG
GCCGCGCTGCTCAAGTCGCTCGGCGCGATGTCCGACCCCGAGCGGGAGGAGGCGCTGCTC
GACCTGGTGTGCACCCATATCGCGGCCGTCCTCGGCTACGACGCGGCCACGCCCGTCAAC
GCGACGCAGGGGCTGCGGGAACTCGGCTTCGACTCCCTGACCGCGGTGGAGCTGCGCAAC
CGGCTCTCGGCCGCGACGGGGCTGAAGCTGCCCGCCACGTTCGTCTTCGACCATCCCAAC
CCGGCGGAGCTCGCCGCGCAGCTGCGGCAGGAGCTGGCCCCGCGCGCGGCGGATCCGCTC
GCCGACGTCCTGGCGGAGTTCGAGCGCATCGAGGACTCGCTGCTCTCGGTCTCCTCGAAG
GACGGCTCGGCGCGGGCCGAACTGGCGGGGCGGCTGCGCGCGACGCTGGCCAGGCTCGAC
GCGCCGCAGGACACGGCCGGCGAGGTCGCGGTGGCCACTCGTACACGTATCCAGGACGCG
TCGGCGGACGAGATCTTCGCGTTCATCGACCGGGACCTCGGCAGGGACGGCGCGAGCGGA
CAGGGCAACGGACAGCCCACCGGGCAGGGCAACGGACACGGCAACGGCAACGGCAACGGC
AACGGCAACGGACACGGTCAGGCAGTGGAGGGGCAGCGATGA
[11] KS32..408
[11] AT563..882
[11] methylmalonyl-CoA751..755
[11] KR1202..1381
[11] ACP1485..1555
[12] KS1581..1958
[12] AT2119..2436
[12] methylmalonyl-CoA2307..2311
[12] dh2485..2652
[12] KR3275..3455
[12] ACP3559..3629
[11] KS94..1224
[11] AT1687..2646
[11] methylmalonyl-CoA2251..2265
[11] KR3604..4143
[11] ACP4453..4665
[12] KS4741..5874
[12] AT6355..7308
[12] methylmalonyl-CoA6919..6933
[12] dh7453..7956
[12] KR9823..10365
[12] ACP10675..10887

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR001227 Acyl transferase domain (Domain)
[560-684] G3DSA:3.40.366.10 [751-872] G3DSA:3.40.366.10 [2116-2240] G3DSA:3.40.366.10 [2307-2425] G3DSA:3.40.366.10
G3DSA:3.40.366.10   Ac_transferase_reg
IPR002198 Short-chain dehydrogenase/reductase SDR (Family)
[1202-1368] 2.29999999999998e-61 PF00106 [3275-3441] 6.19999999999994e-61 PF00106
PF00106   adh_short
IPR006162 Phosphopantetheine attachment site (PTM)
[1513-1528] PS00012 [3587-3602] PS00012
PS00012   PHOSPHOPANTETHEINE
IPR009081 Acyl carrier protein-like (Domain)
[1483-1559] 3.7e-44 G3DSA:1.10.1200.10 [3557-3633] 3.7e-44 G3DSA:1.10.1200.10
G3DSA:1.10.1200.10   ACP_like
[1489-1552] 4.3e-11 PF00550 [3562-3627] 1.8e-13 PF00550
PF00550   PP-binding
[1485-1555] PS50075 [3559-3629] PS50075
PS50075   ACP_DOMAIN
[1478-1598] 5.10001002358244e-29 SSF47336 [3551-3646] 8.40001703163684e-23 SSF47336
SSF47336   ACP_like
IPR011032 GroES-like (Domain)
[3002-3135] 4.19999771339581e-16 SSF50129
SSF50129   GroES_like
IPR014030 Beta-ketoacyl synthase, N-terminal (Domain)
[32-282] 6.99999999999989e-96 PF00109 [1581-1832] 2.39999999999997e-93 PF00109
PF00109   ketoacyl-synt
IPR014031 Beta-ketoacyl synthase, C-terminal (Domain)
[290-408] 5.40000000000002e-47 PF02801 [1840-1958] 1.2e-45 PF02801
PF02801   Ketoacyl-synt_C
IPR014043 Acyl transferase (Domain)
[563-882] 1.60000000000002e-104 PF00698 [2119-2436] 2.99999999999998e-105 PF00698
PF00698   Acyl_transf_1
IPR015083 Polyketide synthase, docking (Domain)
[1-27] 9e-14 PF08990
PF08990   Docking
IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase (Domain)
[561-845] 3.49999466863949e-62 SSF52151 [2117-2419] 4.69998262513195e-63 SSF52151
SSF52151   Acyl_Trfase/lysoPlipase
IPR016036 Malonyl-CoA ACP transacylase, ACP-binding (Domain)
[686-750] 1.39999892049878e-15 SSF55048 [2242-2306] 2.19999900980708e-16 SSF55048
SSF55048   Malonyl_transacylase_ACP-bd
IPR016038 Thiolase-like, subgroup (Domain)
[32-293] G3DSA:3.40.47.10 [294-460] 1.9e-126 G3DSA:3.40.47.10 [1581-1843] G3DSA:3.40.47.10 [1844-2010] 1.9e-126 G3DSA:3.40.47.10
G3DSA:3.40.47.10   Thiolase-like_subgr
IPR016039 Thiolase-like (Domain)
[24-406] 3.79997359309398e-103 SSF53901 [1574-1956] 2.1000026783403e-101 SSF53901
SSF53901   Thiolase-like
IPR016040 NAD(P)-binding domain (Domain)
[1202-1418] 1.39999999999997e-77 G3DSA:3.40.50.720 [3276-3453] 1.10000000000001e-77 G3DSA:3.40.50.720
G3DSA:3.40.50.720   NAD(P)-bd
IPR018201 Beta-ketoacyl synthase, active site (Active_site)
[195-211] PS00606 [1745-1761] PS00606
PS00606   B_KETOACYL_SYNTHASE
IPR020801 Polyketide synthase, acyl transferase domain (Domain)
[565-863] 2.89997807423186e-112 SM00827 [2121-2416] 5.10003242202156e-114 SM00827
SM00827   PKS_AT
IPR020806 Polyketide synthase, phosphopantetheine-binding domain (Domain)
[1486-1558] 8.59998776239544e-34 SM00823 [3560-3632] 2.80000504261099e-35 SM00823
SM00823   PKS_PP
IPR020807 Polyketide synthase, dehydratase domain (Domain)
[2485-2652] 2.0000139277205e-67 SM00826
SM00826   PKS_DH
IPR020841 Polyketide synthase, beta-ketoacyl synthase domain (Domain)
[34-459] SM00825 [1584-2010] SM00825
SM00825   PKS_KS
IPR020842 Polyketide synthase/Fatty acid synthase, KR (Domain)
[1202-1381] 1.90000694315261e-54 SM00822 [3275-3455] 1e-55 SM00822
SM00822   PKS_KR
SignalP No significant hit
TMHMM No significant hit
Monen_00240 Monen_00240   Monen_00260 Monen_00260
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