MUP_00190 : CDS information

Location

Organism	Mycobacterium ulcerans
Strain	Agy99
Entry name	Mycolactone
Contig	BX649209
Start / Stop / Direction	15,406 / 16,440 / + [in whole cluster] 15,406 / 16,440 / + [in contig]
Location	15406..16440 [in whole cluster] 15406..16440 [in contig]
Type	CDS
Length	1,035 bp (344 aa)

Annotation

Category
Product
Product (GenBank)	probable conserved membrane protein
Gene
Gene (GenBank)
EC number
Keyword
Note
Note (GenBank)	MUP019, -, len: 344 aa. Probable conserved membrane protein, weakly similar to several membrane associated proteins from M. tuberculosis e.g. to the C-terminus of two probable serine/threonine-protein kinases Q11053\|PKNH_MYCTU\|Rv1266c (626 aa), fasta scores: opt: 483, E(): 3.7e-16, (29.032% identity in 341 aa overlap); and PKNJ_MYCTU\|Q10697\|Rv2088 (589 aa), fasta scores: opt: 315, E(): 5.4e-08, (25.649% identity in 308 aa overlap). Also weakly similar to P96858\|Rv3576 Possible lipoprotein lppH from M. tuberculosis (237 aa), fasta scores: opt: 380, E(): 1.9e-11, (29.918% identity in 244 aa overlap). Contains a Prosite match to entry PS50099 PRO_RICH Proline-rich region. Contains a membrane spanning region between aa 102 to 124.

Sequence

>[probable conserved membrane protein]
MLGITFGLAPRRMITMSVDTEPTMPSHTWDARPSTGPTPVDPWGPPITTMGQPRPTNPQT
PEARYSWAPPPMAFQPGFGRAPGWPYPPATPNTAPHRASARIAAAVVGAALAVIALIVLI
TTVGGSTKPGAALTHTTPTVSAQPPSTTTTPPPPPPIAPAALAGLLLDTDTINALINSGE
LAVDPKHTTTKLFTDTADHPACGGVLVNASKQVYDGSGWVAAQTQALRDNTTRQHVVYES
VISYPSARTATKMVAQEAHNWQRCNGRSITTTATSYPAQTWFVATVDNHDGMLTALMNQE
GARGWACQHALTARNNIVIDIEVCGADITHQATAIAKKVAQNVH

>[probable conserved membrane protein]
ATGCTCGGTATCACATTCGGATTAGCGCCCAGGAGGATGATCACAATGTCGGTCGACACC
GAGCCCACGATGCCCAGTCACACATGGGATGCGCGGCCCTCAACCGGACCCACCCCGGTG
GATCCGTGGGGTCCACCCATCACCACGATGGGGCAGCCGAGGCCGACCAACCCGCAAACG
CCGGAGGCACGGTATTCGTGGGCCCCACCACCCATGGCCTTTCAACCCGGTTTTGGTCGG
GCTCCAGGCTGGCCGTATCCACCGGCCACACCAAACACTGCCCCGCATCGCGCGTCAGCA
CGCATCGCCGCCGCAGTAGTCGGCGCAGCGCTCGCAGTGATCGCGCTGATAGTGCTCATC
ACCACCGTCGGCGGATCAACCAAACCCGGCGCCGCCCTCACCCACACCACACCGACTGTC
TCAGCACAGCCACCGTCCACTACGACGACCCCGCCCCCGCCCCCGCCCATCGCGCCGGCA
GCCCTGGCAGGGCTGCTGCTCGACACAGACACCATCAACGCGCTGATAAACTCCGGAGAA
CTAGCGGTGGACCCAAAGCACACGACGACGAAGTTGTTCACCGACACCGCCGACCACCCG
GCATGCGGCGGAGTGTTGGTCAACGCCAGCAAACAGGTCTACGACGGCAGCGGATGGGTC
GCAGCGCAAACCCAAGCCCTGCGTGACAACACCACCCGACAACACGTCGTCTACGAATCG
GTAATCAGCTATCCCTCAGCACGCACCGCCACCAAAATGGTTGCCCAAGAAGCCCACAAC
TGGCAACGCTGCAACGGCCGATCCATAACCACCACCGCCACCAGCTACCCGGCCCAGACT
TGGTTTGTCGCCACCGTCGACAACCACGACGGCATGCTCACCGCGTTGATGAACCAAGAA
GGCGCTCGAGGCTGGGCCTGCCAGCACGCATTGACCGCACGCAACAACATCGTCATCGAC
ATTGAGGTATGCGGTGCCGACATCACCCATCAAGCCACCGCAATCGCCAAGAAGGTCGCC
CAAAATGTCCACTGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	No significant hit
SignalP	No significant hit
TMHMM	Transmembrane 1

MUP_00180 MUP_00200