MUP_00640 : CDS information

Location

Organism	Mycobacterium ulcerans
Strain	Agy99
Entry name	Mycolactone
Contig	BX649209
Start / Stop / Direction	158,251 / 157,889 / - [in whole cluster] 158,251 / 157,889 / - [in contig]
Location	complement(157889..158251) [in whole cluster] complement(157889..158251) [in contig]
Type	CDS
Length	363 bp (120 aa)

Annotation

Category
Product
Product (GenBank)	possible conserved membrane protein
Gene
Gene (GenBank)
EC number
Keyword
Note
Note (GenBank)	MUP064c, -, len: 120 aa. Possible conserved membrane protein, shows some similarity with other putative membrane proteins e.g. C-terminus of O06345\|Rv3482c Probable conserved membrane protein from M. tuberculosis (260 aa), fasta scores: opt: 129, E(): 0.39, (30.233% identity in 86 aa overlap). And show some similarity to Mycobacteriophage proteins e.g. AAN12600 Gp39 from Mycobacteriophage (132 aa), fasta score: E(): 0.055, (40.000% identity in 50 aa overlap). Contains several membrane spanning regions towards the C-terminus.

Sequence

>[possible conserved membrane protein]
MTTPPPPPGWYPDPSDPEKRIYWDGAAWSRPASAATEVDKANKSKKTAITIGVCVLVVIG
LVMSMQSVSLMTGSGPVWTGVAVVAAGTAIAFFLRAARWVRVVAALILALALANAGLRRC

>[possible conserved membrane protein]
GTGACCACGCCCCCACCTCCGCCAGGTTGGTATCCAGACCCATCGGATCCTGAAAAACGA
ATCTACTGGGACGGCGCCGCTTGGAGCAGGCCAGCATCCGCGGCGACCGAAGTCGACAAG
GCAAACAAGAGCAAGAAGACGGCGATTACGATTGGCGTCTGCGTACTTGTTGTCATCGGA
CTTGTCATGTCAATGCAGTCAGTCAGCCTCATGACAGGCTCAGGCCCGGTGTGGACCGGC
GTTGCCGTCGTAGCAGCTGGCACGGCAATTGCATTCTTTTTACGCGCTGCCAGGTGGGTC
CGCGTCGTCGCTGCCTTGATCCTGGCGCTTGCACTCGCAAACGCAGGGCTCCGGCGTTGT
TGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR018929 Domain of unknown function DUF2510 (Domain) PF10708 DUF2510
SignalP	Eukaryota Bacteria, Gram-negative
TMHMM	Transmembrane 3

MUP_00630 MUP_00650