Myxa_00050 Myxa_00050   Myxa_00070 Myxa_00070

Myxa_00060 : CDS information

close this sectionLocation

Organism
StrainSga15
Entry nameMyxalamid
Contig
Start / Stop / Direction29,878 / 14,300 / - [in whole cluster]
29,878 / 14,300 / - [in contig]
Locationcomplement(14300..29878) [in whole cluster]
complement(14300..29878) [in contig]
TypeCDS
Length15,579 bp (5,192 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category1.1 PKS
Productpolyketide synthase
Product (GenBank)MxaC
Gene
Gene (GenBank)mxaC
EC number
Keyword
Note
Note (GenBank)
  • PKS; modules 1,2 and 3 contain KS, AT, DH, KR, and ACP regions
Reference
ACC
PmId
[11182319] Novel features in a combined polyketide synthase/non-ribosomal peptide synthetase: the myxalamid biosynthetic gene cluster of the myxobacterium Stigmatella aurantiaca Sga15. (Chem Biol. , 2001)
comment
myxalamid生合成gene clusterの報告。
MxaC: PKS domains
(Module 4: KS, AT, DH, KR, ACP)
(Module 5: KS, AT, KR, ACP)
(Module 6: KS, AT, DH, KR, ACP)

mxaCはmodule 4-6をコード。
mxaCのinactivationでmyxalamidsは産生されなくなる。

mxaCでコードされるmodule 5は必要なDH domainを欠いており、このためにMxaEのDH domainが使用されるかもしれない。

系統樹やalignmentでAT domainの解析を試みているが、例外的なmotifと基質特異性の関連を導くのは無理で、構造解析が必要だとしている。

close this sectionPKS/NRPS Module

4 malonyl-CoA
not conserved HAFHS
5 malonyl-CoA
not conserved HAFHS(H->Y)
6 malonyl-CoA
KS36..405
AT559..877
DH922..1096
KR1466..1645
ACP1739..1812
KS1851..2217
AT2372..2689
KR2988..3181
ACP3281..3351
KS3374..3749
AT3903..4219
DH4263..4432
KR4795..4973
ACP5071..5141

close this sectionSequence

selected fasta
>polyketide synthase [MxaC]
MANRNDESNELSPAKRMLVALEKMQTRLNAVEGAAKEPIAIVGMACRFPQADNVEAFWRL
LQGGVDAVREIPLERWPKDEVADIGDGAMRWGGFLDSVDSFDPGFFGISPREAVRMDPQQ
RLLLEVAWEALEDAGLDVDKLSGSRSGVFIGACNDDYHCMQVERPETGDAFSATGVAASV
LSGRLSYLFNLQGPSLVVDTACSSSLVSLHLACQSLRNRECNMALAGGVNLILSPQSVLL
VSKLQALSPDGRSKAFDASANGFTRGEGCGIVVLKRLSDALADGDHILATIRGSAINQDG
KSTGLTTPNVLSQQALIRQALESSGLKAEQVSYVEAHGTGTPLGDPIEAEALRETYGVPR
PDGSVCGIGSVKTNVGHLESAAGIAGIMKVVLAMRHQSIPPHLHLKQVNPRIQLEGSALT
IPTRLTPWKASGQPRRAGVSSFGISGTNAHVIIEEAPAPVAKDALPQRPEVLPLSARSRE
ALVALAERYAERLGREGGGSLSDVCYTASAHRTHHTHRLAVLADSREHTAERLRAFARGE
QPSGAWSGRKAFGGRRKIVFVYPGQGAQRAGMGRALMESEPVFRDALVKVDKALQPHLGW
SVLDEIAADEQRSRLAEIDVNQPVLFAVEVALTALWRSWGIEPDAVMGHSMGEVVAAHVA
GALSLEDAVLIICHRSKLMRTLGGRGATMAMVELSVEEAEEAIRPWNGKIWLGGLNGPRS
QVLSGEPEAVKEAVEALGKRGVFTRWVKMDVPSHTPLVEVISRELEGRIARITPRAADIP
LCSTVTGEFLDGAKLDAAHWGNNLRNPVRFAAAAQHLLASDHGTFVEVSPHPVLLPAVEQ
TMSAGNTEGVVLASLRRNEDERHTMLSSLGALYSSGHRVAWNRVYPGKGQLVPLPTYPWQ
RERFWMEPAVRGVRASRTSSGHPLIGERIDLSAQGEVSRLWQVQLGPKHFPLLAEHRVQG
VPALPAAAMADMALSAAKQTLGEPVSLEDVSFSALLSFPEDEERVLQLWLSTERPGASAF
RLFSAPVMRETPSDELTWALHAEGSLRHGDASVVEKAAPVALDELRARCGEEASVEAHYQ
TLKEIGLEYGPSFRVVRELYRAKGEALGRVQLEGELTAEEERYSLHPALLDGCFQVLAAA
LEGLDSEGGVYVPVALSRLRVLVRPEAALWSHVRIVSGAEAGSNTIECDVTLLNDQGRVV
AEVRRLVCKKIAAASAPADEVDRWIYSAQWEPQQRQARAETGSSRTAGRWLVFADARGIG
QSLASGLAERAGGCVVVEAGPSYERLEADRYRINPSKLEDFQALLKEAFSDQSPCKGMVH
LYGLDVASNVTEPESFERALSLSSTSVVYLLQAWAQRGWRDTPRLWLVTTGVQVIASGEQ
PGSPAAAPLVGLAAVITHEHPELRCAHVDLSAQPSPEEIASLTEELLGDGAEDRIALRGA
VRHVARLGRGISGRKAAEPREFTADGTYLITGGLGGLGLEVAKWFIQRGARNLALTGRGA
PSEEAQKVLGELRANGAEVRVYRADVTSAADVARLLGSIDSELPPLRGVVHAAGVIADGV
LTQLDEPRLRAVLAPKVQGAWNLHVQTQGRPLELFVMFSSAASMMGSPGQGNYAAANAFM
DVLAHHRRAAGLPGLSVNWGPWADVGLAAVATNRGDRLALRGVGNMPPAQALEALGRLLV
QEAAQVAVVPLDLRQWREFYLSAAQSPFLSVLMQEKVSTPASRKGSARELLAAAEPEQRK
GILEGYLREQLGRILRMEPSRIEPDQPFGDLGMDSLTGLELRNRIESGLKLTLSATLIYA
YPTVQALTTYLYGKLEPVLEAEARPTVRPTQTEPRVSVGVAPASQGPELLAIVGMGCRFP
GGANEPEAYWRLLSDGVDAVREVPADRWQSSTDAAEHKGTRWGGFLDRVDGFDPEFFGIA
PREAVAMDPQQRLLLEVAWEALENAGLPKSRLAGTRTGVFVGVCGYDYAMLQAERDVEGD
VYSVIGCSNSVIAGRLSYLMDLRGPAMTVDTACSSSLVALHLASQSLRNRECDAALVGGV
NLLLSQRPSSWLSKLMALSPDGRCRTFDSRANGFVRGEGCGVVVIKRLSDALASGDNVLG
VIRASAVNQDGGSTGLTAPNVLSQQALIRDALKSANLSPKEIGYIEAHGTGTPLGDPIEV
EALRETYGVRRDDGFPCFLGSAKTNIGHLEAAAGMAGLIKVLLALRHEAIPKHLHFKALN
PRITIEDTPFVIPTQMQPWPVSQRRRYAAVSSFGISGTNAHVILEEAPSPLPAPVAAEAG
AQLLALSARSEGALRALARSYQELLAKPQDEALRLEDIAYTAALRRNPHEHRLSVAGRSK
QELSEQLQSFLDGSTPPYLTTGLAESRREKVVFVFGGQGSQWQGMGRDLLARSEPFAAAL
RECDSLLAQHTGFSIIEALEVEGPTSRLDETEVAQPAIFAIQVALAAAWRALGVVPAAVV
GHSVGEIAAAHVAGALSLAEAARLVAHRSRLMQRATGKGRMAAVELSSEDAQRELARYSD
RLSVGAINDARSVVLSGEPSALGEVLESLRARGLSTRDLGVNYAFHSQQMASLQPELIEA
LGQLETRPTSIPMISTVSGQVIEGQALDAAYWASNIREAVRFSDAVGALIDEGHRLFVEL
GPQPALGRYVSQALERRELEGAAVPSLRKGRDGQTVMLGALGGLHVKGFPVDWARLFPSG
GRLVSLPLYPWQRSRYWIDLDDASATSQAPTTSARGVASGAPASSTSRPDDWVYDITWQA
RERGAASPRAQQGTGTWLILGHREGTGAALAALLEQRGEPCWLVVPGEEAEVLGPTLRSI
HPQRSEHFERLLQEVGPIRAVVHLWGADASPASEPKLAEVESAQQLGVHAVVRLVQAFLK
SGSASGARLWLCTRGSQAVGGAMGGSPLQAPLWGLGRVMALEYPDAWGGLLDLDPSAPAG
EVEALWKELSGFDGEDQAAFRDGVRYVARLVPAAPKPALAPVALRPDASYLVTGGLGGLG
LHVARWLVSKGARHLVLLGRKGLPDRSEWPTIARESDVGRQIAAVEALEANGAVVHALSA
DVGNPIRMAEVIQSIQQGPAPLKGIIHAAGVSTLVSLDTMDEAALASILRPKVTGGWVLH
QVTQGLDLDFTVYFSSGSAVWGSARMAHYAAGNQFLDSLAHYRRARGLHALSINWGPWAA
EGMVAEEGLRWFERMGLRGVSVEGGLHVLEALLAMDVTQRSVAQIDWSLFKSVYESRTRK
PLLEALGPASVPVPRSVEVAAGNEELAQLRNASPARRKELVIAWVREEVARVLGFPSSAS
VKLEQGFFETGMDSITAVELRRRLVARFGVQLATTVAFDRPTVLALSTHILQDVLRLDVE
AKEEASRVVGNATEPIAIVGIGCRVPQASGPEAFWKLLEGGVDAIREVPASRWKVEDYYD
PQPGVPGKTYTRWGGFLDGADQFDAQFFGIAPREAANMDPQQRLLLEVAWESLEHAGIAP
ARLANTRTGVFIGIGSNEYAMLNGVGSASAAGDAYIATGNDSSFAAGRLAYLLRFQGPTM
SLNTACSSSLVAVHLACQSLRAGESNLALAGGVNMTLAPHSTIYLAQLRALSQDGRCKTF
DASADGYVRSEGCGIVVLKRLSDAKRDGDDVLAVIRGSAVNHDGPSSALTVPNGDAQQQV
LRAALANAGVAPADVDYIEAHGTGTSLGDPIEVQALANVLGQGRTSEQRLLIGSVKTTIG
HLEAAAGIAGLIKVVLAHRHGVVPPHLHLKKLNPHIELNGFPLDIPTQVTPWPERARPRI
AGISAFGLSGTNAHVLVEEAPAPEPRAEQAERSLHVLALSAKTKGALTQLAARVGEYLAE
QPEQKLADVCHAANTQRTWFSHRLALVVESVEQTRERLLAFARGEEVPRLAQNRVEGEDP
KVVFVFTGQGAQYAGMGRELYETEPVFRAALDRCNALIEGKWAESLLSVMHGTGSRIDDT
EYTQPALFALEYALAELWRSWGVEPWAVLGHSVGEYVAACVAGVMELEEALGLITERARL
MQALPRNGEMVAVSASEAQVQEMLAPYADRVSIAAVNGPADTVISGEREAVEAISASLQA
KGVKARRLTVSHAFHSPLMDPMLDAFEKAAGKIAFRAPRLHLASNVTGQLLGDGAVLDAA
YFRRHVREAVRFHDGLKALRALGGTVFVEVGPHPTLTSMALKGLGDDAGTWLPSLRKGQP
EQPQILSSLGALYTQGVAVNWIALNGERHRSPVALPVYPWQHQRHWLETAKTPRPVAPTT
CAQSLVGQRVRSPLNKSIVFEGRYSAQSLPFLDDHRLYGTVVVPGSCHIARIIATAAQSF
GTGPYTIEKCLFSQPIVLADDEEQLVQLVLAPKGQGRYDFEIYSLSPTADEETEGWLLNG
TGTLQVGGDGHSRPEPISRQDIEARCTRLMESGLYEKNWDIGFNLGHAFRWIERVQSGGR
EALCQMRLPTERDDRGLYVHPGLVDSFLQAMGTDLIREDAQLSTVYVPISVERFRFYEQP
TGPVWAYAVRRDAEEAVGEVITGDVYVVNAEGRVLIEIEGLKHKRAPREALMAVLRHGQR
DTLYELGWKRQPLPEGVPGSGRWIVFADETGTGEALAERLLKSGCRPVLVRPGEAFARQD
GDRFTLDAQRAEDYARLLKEAVPSGESLGGVVHLWAMRGAHGNDVESLHAAHQLGGGSAL
HLAKAVASFPSAARLWLVTRGARALPSHSGPLALNQVPVWGLGVVFSQEHPERCGALIDL
DPSASGEDATAIWRELSAADGERQVVIREGQRHVARIRASRDEQRNAAQRLRPDASYLLT
GGLGGLGLSLARWMVDQGARNLVLIGRGAAKPEAQETLRTLEAAGAKVLVLQADVSKQAD
VRRTLEEAEKLAPLRGVVHAAGVLDDGVLLQQDWERFSRVFAPKVDGAWHLHELTKDKEL
DFFVLYSSAATLLGPPGQGSYAAANAFLDALAHHRRSQGLPALSINWGPWAEVGMAAQHA
SRFQTQGIEAFSPEAALKAFSQALSRAQPQLTLMQVQWSRYLAQYPRGAAPTVLAEVSGR
AVAEPEANGHSASEFRRRLESAEPRQRLPLLLEHVQGEAVRVLGLDASASLEPRQRLFEV
GMDSLMALELRNRLQTTVGASLPSTLVFDYPTAEAIANYLLGEALGLEKQSAGNAQGEVQ
DTALLERIMELSPDELAASLEAKLSALMEEGS
selected fasta
>polyketide synthase [MxaC]
ATGGCAAACCGCAACGACGAGTCCAACGAGCTATCTCCCGCCAAGCGCATGCTGGTGGCG
TTGGAGAAGATGCAGACGCGGCTGAACGCCGTGGAGGGGGCCGCGAAGGAGCCCATTGCC
ATCGTGGGCATGGCGTGCCGCTTCCCTCAGGCGGACAACGTGGAGGCCTTCTGGCGGCTG
CTCCAGGGCGGCGTGGATGCCGTGCGGGAGATTCCCCTGGAGCGCTGGCCCAAGGATGAG
GTCGCCGACATCGGCGATGGGGCCATGCGGTGGGGTGGCTTCCTGGACTCGGTGGATTCG
TTCGACCCCGGCTTTTTCGGGATCTCCCCCCGTGAGGCGGTGAGGATGGATCCCCAGCAG
CGCTTGCTGCTGGAGGTGGCGTGGGAGGCGCTCGAAGACGCGGGGCTGGATGTCGACAAG
CTCTCGGGCAGCCGCAGCGGCGTCTTCATCGGTGCCTGCAACGACGACTACCACTGCATG
CAGGTGGAGCGCCCGGAGACAGGGGACGCGTTCAGTGCCACGGGCGTTGCCGCGAGCGTT
CTGTCGGGCCGGTTGTCCTATCTTTTCAACCTGCAGGGGCCGAGCCTGGTGGTGGACACG
GCGTGCTCGTCCTCGCTCGTGTCGCTGCACCTGGCCTGCCAGAGCTTGCGCAACCGTGAG
TGCAACATGGCGCTCGCGGGCGGCGTCAACCTGATCCTCTCGCCGCAGTCCGTGTTGCTC
GTGTCCAAGCTGCAGGCGCTTTCGCCCGATGGCCGGAGCAAGGCGTTCGATGCTTCCGCC
AATGGCTTCACCCGCGGCGAAGGGTGCGGAATCGTCGTCCTCAAGCGCCTCTCCGATGCG
CTGGCGGACGGTGATCACATCCTGGCGACGATTCGCGGCTCGGCGATCAACCAGGATGGC
AAGTCGACAGGGCTGACCACGCCGAACGTGCTCTCGCAGCAGGCGCTCATCCGCCAGGCG
CTGGAGAGCTCTGGGCTGAAGGCCGAGCAGGTGAGCTATGTGGAAGCGCACGGCACCGGA
ACGCCGCTCGGCGATCCGATAGAGGCGGAGGCGCTGCGTGAGACGTATGGCGTCCCGCGC
CCCGATGGCAGCGTGTGCGGCATCGGCTCGGTGAAGACCAATGTGGGGCACCTGGAGTCC
GCTGCGGGCATTGCGGGCATCATGAAGGTGGTCCTCGCGATGCGCCACCAGAGCATCCCG
CCGCACCTGCACCTCAAGCAGGTCAACCCACGCATTCAGCTTGAGGGCAGCGCGCTCACC
ATCCCCACGCGACTCACGCCGTGGAAGGCTTCTGGACAGCCGCGCCGCGCGGGCGTCAGC
TCGTTTGGCATCAGTGGGACCAACGCCCACGTCATCATCGAGGAGGCACCCGCCCCGGTG
GCGAAGGACGCGTTGCCCCAGCGTCCAGAAGTGTTGCCCTTGTCCGCGCGCAGCCGCGAA
GCCCTCGTGGCCCTCGCGGAGCGCTATGCGGAGCGTCTTGGCCGCGAGGGGGGAGGAAGC
CTCTCCGACGTCTGCTACACGGCATCCGCTCATCGCACGCACCACACCCATCGTCTCGCG
GTGCTGGCGGACTCGCGTGAGCACACCGCTGAGCGGCTTCGGGCGTTCGCGCGGGGAGAG
CAGCCGAGTGGCGCTTGGTCGGGCCGCAAGGCATTCGGCGGGCGCCGGAAAATTGTCTTC
GTCTATCCAGGGCAGGGCGCGCAGCGGGCCGGCATGGGCCGGGCGTTGATGGAGAGCGAG
CCGGTCTTCCGTGATGCGCTCGTCAAGGTGGACAAGGCGTTGCAGCCTCACCTGGGCTGG
AGCGTGCTCGACGAGATCGCGGCGGACGAGCAACGCTCGCGCCTGGCCGAGATTGACGTC
AACCAGCCGGTGCTTTTCGCGGTCGAGGTGGCCCTCACGGCCCTGTGGCGCTCGTGGGGG
ATCGAGCCCGATGCCGTGATGGGACACAGCATGGGCGAGGTGGTCGCGGCACATGTGGCC
GGGGCGCTGAGCCTCGAGGACGCCGTCCTCATCATCTGCCATCGCAGCAAGCTCATGCGC
ACCCTGGGAGGACGGGGCGCCACGATGGCCATGGTCGAGCTCTCGGTGGAAGAGGCCGAG
GAGGCGATACGCCCCTGGAACGGCAAGATCTGGCTGGGGGGCCTGAATGGTCCTCGCTCG
CAGGTGCTGTCGGGCGAGCCAGAGGCGGTCAAGGAAGCGGTCGAGGCGCTCGGGAAGCGC
GGCGTGTTCACCCGCTGGGTGAAGATGGACGTGCCGTCGCACACCCCGCTGGTTGAGGTG
ATCAGCCGAGAGCTGGAAGGGCGGATCGCGCGCATCACGCCCCGCGCCGCGGACATTCCC
CTTTGCTCCACCGTGACGGGAGAGTTCCTGGATGGGGCGAAGCTGGACGCCGCCCACTGG
GGGAACAACCTTCGCAATCCGGTGCGCTTCGCGGCGGCGGCGCAGCACCTGCTCGCGAGC
GATCACGGAACCTTCGTCGAAGTGAGCCCGCACCCCGTTCTGCTTCCGGCCGTCGAGCAG
ACGATGAGCGCGGGGAACACGGAAGGCGTGGTGCTTGCGTCCCTGCGGCGGAATGAGGAC
GAGCGGCACACCATGCTGTCCTCGCTCGGAGCCCTCTATTCCTCGGGACACCGCGTCGCG
TGGAACCGGGTGTATCCGGGCAAGGGGCAGCTCGTGCCACTGCCCACGTATCCCTGGCAG
CGCGAGCGTTTCTGGATGGAGCCTGCCGTCCGTGGGGTACGCGCGTCGCGGACCTCCTCT
GGACACCCGCTCATTGGCGAGCGCATCGACCTGTCCGCGCAAGGAGAGGTCTCGCGCCTG
TGGCAGGTGCAGTTGGGGCCGAAGCACTTTCCTTTGCTGGCGGAGCACCGCGTTCAGGGA
GTGCCCGCGCTGCCTGCGGCGGCCATGGCCGACATGGCGCTGAGTGCGGCAAAGCAGACG
CTCGGAGAGCCGGTTTCTCTCGAGGACGTGAGCTTCAGTGCGCTCCTGTCGTTCCCCGAG
GACGAGGAGCGGGTACTCCAACTGTGGCTCTCGACGGAGCGTCCAGGCGCGAGCGCATTC
CGTCTCTTCAGCGCGCCGGTCATGCGCGAGACGCCGTCCGACGAGCTGACCTGGGCGCTT
CATGCTGAAGGCTCCCTGCGGCACGGGGACGCGTCTGTCGTGGAGAAGGCAGCGCCTGTC
GCGCTCGATGAACTCCGAGCGCGTTGTGGCGAGGAGGCCTCTGTTGAGGCGCACTACCAG
ACCTTGAAGGAGATTGGTCTGGAGTACGGTCCCAGCTTCCGGGTGGTGCGAGAGCTGTAT
CGGGCGAAGGGAGAGGCGCTGGGCCGCGTGCAGCTCGAGGGCGAGCTGACGGCTGAGGAG
GAGCGCTACAGCCTGCACCCGGCACTGCTCGACGGCTGCTTCCAGGTTCTGGCGGCGGCG
CTCGAGGGGCTCGACAGCGAAGGGGGCGTTTACGTCCCCGTGGCGCTGTCACGGCTGCGC
GTCCTGGTGCGCCCGGAGGCCGCGCTCTGGAGCCACGTCCGGATCGTCAGCGGTGCCGAG
GCGGGCTCGAACACCATCGAGTGTGACGTCACGCTCCTGAATGATCAGGGCAGGGTGGTG
GCGGAGGTGCGGCGGCTGGTCTGCAAGAAGATCGCCGCTGCCAGCGCCCCGGCCGACGAA
GTCGACCGCTGGATATACTCCGCCCAGTGGGAGCCGCAGCAGCGTCAGGCTCGGGCCGAG
ACGGGGAGTTCGCGGACCGCGGGCCGTTGGCTCGTCTTCGCGGATGCTCGGGGTATTGGC
CAGTCGCTCGCCTCGGGGCTCGCGGAGCGGGCTGGGGGCTGCGTCGTGGTGGAGGCAGGG
CCCTCCTACGAGCGGCTCGAGGCGGATCGTTATCGCATCAACCCCTCGAAGCTCGAGGAC
TTCCAAGCGCTTCTGAAAGAAGCGTTCAGCGACCAGTCGCCCTGCAAGGGCATGGTGCAC
CTCTACGGGCTCGATGTGGCGTCCAACGTGACGGAGCCCGAGTCTTTCGAGCGTGCGTTG
TCCCTGAGCAGCACGAGCGTGGTGTACCTGCTTCAGGCGTGGGCGCAGCGCGGGTGGCGC
GACACGCCGCGATTGTGGCTGGTGACAACGGGTGTCCAGGTGATCGCCTCGGGCGAGCAG
CCGGGCTCTCCGGCCGCAGCACCCCTGGTGGGCCTCGCGGCGGTCATTACCCACGAGCAC
CCCGAACTGCGTTGTGCTCACGTGGATCTGAGCGCGCAGCCTTCGCCCGAGGAGATCGCC
TCGCTGACCGAGGAGCTTCTGGGGGATGGGGCGGAAGATCGAATCGCGTTGCGTGGGGCT
GTGCGCCACGTCGCGCGGCTGGGCCGCGGCATCTCTGGGCGCAAGGCGGCGGAGCCCCGT
GAGTTCACGGCGGATGGCACCTACCTCATCACCGGCGGCCTGGGTGGGCTCGGGCTGGAG
GTGGCGAAGTGGTTCATCCAGAGGGGAGCCCGGAATCTGGCGCTCACCGGGCGTGGGGCT
CCGTCCGAAGAGGCCCAGAAGGTGTTGGGAGAGCTCCGTGCAAACGGAGCCGAGGTGCGT
GTCTACCGGGCGGACGTCACGAGTGCCGCCGACGTGGCGCGCTTGCTCGGATCGATCGAT
TCGGAGCTGCCTCCCCTGCGGGGCGTCGTCCACGCGGCCGGTGTCATCGCCGATGGCGTG
CTGACGCAACTGGATGAGCCTCGGCTGCGCGCGGTGCTGGCGCCAAAGGTTCAGGGTGCG
TGGAACCTGCATGTGCAGACGCAGGGCCGTCCCCTGGAACTCTTCGTGATGTTCTCCTCG
GCTGCGTCGATGATGGGCTCGCCGGGCCAGGGCAACTACGCGGCGGCCAACGCCTTCATG
GACGTACTCGCGCACCACCGGCGCGCGGCAGGGCTCCCTGGGTTGAGCGTCAACTGGGGA
CCCTGGGCCGATGTGGGGCTCGCCGCCGTGGCGACGAACCGGGGCGACCGCTTGGCGCTG
CGAGGCGTGGGCAACATGCCGCCCGCGCAGGCCCTCGAAGCCCTTGGCCGTCTCTTGGTT
CAAGAGGCTGCCCAGGTGGCGGTGGTGCCGCTCGACTTGCGGCAGTGGCGCGAGTTCTAC
CTGAGCGCCGCGCAGTCGCCCTTCCTCTCCGTGCTGATGCAGGAGAAGGTGAGTACCCCG
GCTTCGCGCAAGGGCAGTGCGCGTGAATTGCTGGCAGCGGCGGAGCCAGAGCAGCGGAAG
GGAATCCTGGAGGGCTACCTGCGCGAGCAGCTCGGGCGCATCCTCCGCATGGAGCCGTCG
CGCATCGAACCCGATCAGCCCTTTGGCGATTTGGGAATGGACAGCCTGACGGGCTTGGAG
CTGCGCAACCGCATCGAGTCGGGCCTGAAGCTCACGCTGTCCGCGACCCTCATTTACGCC
TACCCGACGGTGCAGGCGCTGACGACGTACCTGTACGGCAAGTTGGAGCCCGTGCTTGAG
GCCGAGGCGCGCCCCACGGTTCGCCCCACCCAGACCGAGCCCCGGGTTTCCGTGGGAGTG
GCTCCGGCTTCCCAAGGACCCGAGCTTCTCGCCATCGTTGGCATGGGGTGCCGCTTCCCG
GGCGGCGCCAACGAGCCGGAGGCGTACTGGCGGCTGTTGAGTGACGGGGTGGATGCGGTT
CGCGAGGTCCCCGCTGATCGCTGGCAGAGCAGCACGGACGCCGCGGAGCACAAGGGCACG
CGCTGGGGCGGCTTCTTGGATCGCGTGGATGGCTTCGATCCGGAATTCTTCGGGATCGCC
CCTCGCGAGGCCGTGGCGATGGATCCGCAGCAGCGCCTGCTGCTTGAGGTAGCCTGGGAG
GCGCTCGAGAATGCCGGTCTGCCGAAGTCGCGACTGGCGGGCACCCGAACGGGCGTCTTC
GTCGGCGTGTGTGGCTATGACTACGCCATGCTGCAGGCGGAGCGCGATGTCGAGGGCGAC
GTCTACTCGGTCATCGGCTGCTCCAACAGCGTGATTGCCGGACGGCTTTCGTACCTGATG
GACCTGCGTGGCCCGGCCATGACCGTGGACACGGCATGCTCGTCCTCGCTGGTGGCGTTG
CACCTGGCCAGCCAGAGCCTGCGCAACCGCGAGTGCGATGCCGCGCTCGTGGGGGGCGTC
AACCTGCTCCTCTCTCAGCGGCCGAGTTCTTGGCTCTCCAAGCTCATGGCTCTGTCGCCG
GACGGGCGTTGCCGGACCTTCGATTCGAGAGCCAATGGCTTCGTGCGTGGCGAGGGCTGT
GGCGTCGTCGTGATCAAGCGGCTCTCCGATGCGCTGGCCAGTGGGGACAACGTCCTCGGG
GTGATCCGCGCTTCGGCCGTGAACCAGGATGGTGGTTCCACCGGACTGACGGCACCCAAC
GTGCTGTCTCAGCAGGCACTGATCCGCGATGCCCTGAAGTCGGCCAACCTGTCTCCCAAG
GAGATCGGTTACATCGAAGCCCACGGCACCGGGACGCCGCTCGGCGATCCGATAGAGGTC
GAAGCCCTGCGGGAAACCTATGGCGTCCGGCGCGACGACGGGTTCCCCTGCTTCCTTGGC
TCGGCGAAGACGAACATCGGACACCTGGAGGCAGCGGCCGGTATGGCGGGCCTCATCAAG
GTTCTCCTGGCCCTGCGGCACGAGGCCATTCCGAAGCACCTGCACTTCAAGGCGCTCAAT
CCCCGCATCACAATCGAAGACACGCCCTTCGTCATCCCGACGCAAATGCAGCCGTGGCCG
GTCTCTCAGAGGCGCCGTTACGCGGCCGTGAGTTCCTTCGGCATCAGCGGGACCAACGCG
CATGTGATTCTCGAGGAGGCTCCCTCGCCGCTCCCCGCGCCCGTGGCCGCCGAGGCCGGG
GCGCAGCTCCTTGCCCTGTCCGCGAGGAGCGAGGGCGCGCTGCGAGCGCTCGCGCGCTCG
TACCAGGAACTCCTGGCAAAGCCTCAGGACGAGGCGCTTCGCCTCGAAGACATCGCCTAC
ACCGCGGCGCTCCGGCGCAACCCCCACGAGCACCGGCTCTCCGTGGCTGGACGCTCCAAG
CAGGAGTTGAGCGAGCAACTTCAGTCTTTCCTCGATGGTTCGACGCCGCCGTACCTCACC
ACGGGGCTCGCCGAGAGTCGGAGGGAGAAGGTCGTCTTCGTCTTCGGCGGTCAGGGTTCA
CAGTGGCAGGGCATGGGGCGGGACCTCCTCGCGCGGAGCGAGCCTTTCGCCGCTGCGCTG
CGCGAGTGCGATTCGCTGCTGGCCCAGCACACCGGGTTCTCGATCATCGAAGCGCTCGAG
GTTGAAGGCCCCACGTCGCGGTTGGATGAGACGGAAGTGGCGCAGCCCGCCATCTTCGCG
ATCCAAGTCGCGCTCGCGGCGGCATGGCGTGCGCTGGGTGTCGTCCCGGCTGCGGTCGTG
GGCCACAGCGTGGGAGAGATCGCCGCCGCGCACGTGGCTGGGGCGCTGAGCCTGGCCGAA
GCGGCGCGACTGGTGGCGCACCGGAGCCGCCTCATGCAGCGGGCCACCGGCAAGGGCCGC
ATGGCCGCGGTCGAGCTTTCGTCCGAGGACGCCCAGCGCGAACTCGCGCGGTACTCCGAT
CGGCTGTCAGTCGGTGCCATCAACGACGCCCGGTCCGTTGTCCTCTCTGGAGAGCCCTCG
GCGCTCGGGGAGGTGCTCGAATCCCTGCGGGCGCGTGGACTCTCCACGCGTGATCTCGGC
GTCAACTACGCGTTCCACAGCCAGCAGATGGCATCGCTTCAGCCCGAATTGATCGAGGCG
CTGGGGCAACTCGAGACGCGGCCGACGTCCATACCGATGATCTCGACGGTGAGCGGCCAG
GTCATCGAGGGCCAGGCGCTGGATGCGGCCTATTGGGCGAGCAACATCCGCGAGGCCGTG
CGCTTCTCCGACGCCGTGGGCGCCCTGATCGATGAAGGCCACCGGCTCTTCGTGGAGCTC
GGGCCTCAGCCCGCGCTCGGTCGGTATGTCTCCCAGGCGCTCGAGCGCCGCGAGCTGGAA
GGCGCGGCGGTACCCTCCCTGCGCAAGGGCCGGGATGGCCAGACGGTGATGCTCGGCGCG
CTGGGCGGGCTCCACGTGAAGGGCTTCCCCGTGGACTGGGCCCGGCTCTTCCCCTCGGGG
GGGCGTTTGGTGTCGCTGCCCCTCTACCCATGGCAGCGCTCCCGGTACTGGATTGATCTC
GACGACGCCTCGGCGACGTCCCAGGCTCCGACAACCTCGGCGAGAGGCGTGGCCAGCGGT
GCTCCCGCTTCGAGCACGAGCCGACCAGACGATTGGGTCTACGACATCACGTGGCAGGCG
CGTGAGCGCGGGGCGGCTTCTCCGCGCGCGCAGCAGGGAACGGGGACCTGGTTGATCCTC
GGCCATCGCGAAGGCACGGGCGCCGCGCTGGCGGCCCTGCTCGAGCAGCGGGGCGAGCCG
TGCTGGTTGGTCGTTCCCGGGGAGGAAGCGGAGGTCCTCGGTCCAACGTTGCGGTCGATC
CACCCGCAACGTTCAGAGCATTTCGAGCGGTTGCTCCAGGAGGTGGGCCCGATTCGGGCC
GTCGTGCACCTGTGGGGAGCGGATGCTTCGCCAGCCTCGGAGCCCAAGCTCGCGGAGGTT
GAGTCCGCGCAGCAGCTGGGCGTCCACGCGGTGGTGCGCCTCGTGCAGGCCTTCCTGAAG
AGTGGTTCCGCGAGCGGTGCTCGGCTGTGGCTGTGCACCCGGGGTAGCCAGGCGGTGGGC
GGAGCGATGGGGGGCTCGCCCTTGCAGGCACCGTTGTGGGGCCTTGGGCGCGTCATGGCG
CTCGAGTACCCGGATGCGTGGGGTGGGTTGCTGGATCTGGATCCGAGCGCTCCCGCGGGT
GAGGTGGAGGCGCTGTGGAAAGAGCTGTCTGGCTTCGATGGAGAGGACCAGGCTGCCTTC
CGGGACGGGGTACGCTACGTGGCGCGGCTCGTGCCGGCGGCGCCGAAGCCCGCGCTGGCG
CCTGTCGCGCTTCGTCCGGATGCGTCGTACCTGGTCACGGGTGGCCTCGGTGGGTTGGGG
CTGCACGTGGCGAGGTGGTTGGTCTCGAAGGGCGCGCGGCACCTGGTGCTGCTGGGCCGG
AAGGGGCTGCCCGACCGAAGCGAGTGGCCGACGATTGCCCGCGAGAGTGACGTGGGGCGG
CAGATTGCCGCGGTCGAAGCCCTGGAGGCCAATGGGGCCGTCGTTCACGCCCTCAGTGCG
GATGTGGGCAATCCGATCCGCATGGCGGAGGTGATTCAGTCGATCCAGCAGGGTCCAGCG
CCGCTGAAGGGCATCATCCACGCCGCGGGCGTGTCCACCCTCGTGTCGCTCGATACGATG
GACGAGGCGGCACTCGCTTCCATTCTGCGTCCGAAGGTGACCGGTGGTTGGGTGCTGCAC
CAGGTGACGCAAGGGCTGGACCTGGACTTCACCGTCTACTTCTCGTCGGGCTCGGCCGTG
TGGGGCTCGGCGCGGATGGCGCACTACGCCGCTGGCAACCAGTTCCTCGATTCGCTTGCC
CACTACCGCCGTGCGCGGGGTCTGCACGCGTTGAGCATCAACTGGGGACCGTGGGCCGCC
GAGGGCATGGTCGCCGAAGAGGGCCTGCGCTGGTTCGAGCGCATGGGCCTCCGGGGTGTC
TCCGTGGAGGGCGGGCTCCACGTGCTGGAGGCGTTGCTCGCCATGGACGTTACCCAGCGC
AGCGTGGCCCAGATCGATTGGAGCCTCTTCAAGTCCGTGTATGAGTCGCGGACGCGCAAG
CCCTTGCTGGAGGCGCTCGGTCCCGCGTCGGTTCCCGTGCCGCGCTCAGTGGAGGTGGCC
GCCGGAAACGAGGAGCTGGCGCAGTTGCGCAACGCTTCGCCCGCGCGCCGCAAGGAACTG
GTGATCGCGTGGGTCCGTGAGGAAGTGGCCCGGGTGCTTGGCTTCCCGTCGAGTGCCTCG
GTCAAGCTGGAGCAGGGCTTCTTCGAGACGGGCATGGATTCGATCACCGCCGTGGAGTTG
CGGCGGCGGTTGGTGGCCCGGTTTGGCGTCCAGCTCGCGACCACGGTCGCCTTTGATCGT
CCCACCGTTTTGGCGCTCTCGACCCATATCCTGCAGGACGTGCTCCGGCTGGATGTGGAG
GCCAAGGAGGAGGCGAGCCGCGTCGTGGGCAACGCCACGGAGCCGATTGCGATCGTCGGC
ATTGGCTGCCGAGTCCCGCAGGCTTCGGGTCCGGAGGCGTTCTGGAAGCTGTTGGAGGGA
GGCGTGGACGCCATCCGCGAAGTGCCTGCCTCGCGGTGGAAGGTCGAGGACTACTACGAC
CCGCAGCCCGGCGTCCCGGGGAAGACCTACACCCGGTGGGGTGGTTTCTTGGATGGGGCT
GACCAGTTCGACGCCCAGTTCTTCGGGATCGCCCCTCGCGAAGCGGCGAACATGGACCCG
CAGCAGCGCCTCCTGCTGGAGGTGGCCTGGGAGTCCCTGGAGCACGCGGGAATCGCTCCG
GCGCGCCTGGCCAACACCCGCACTGGCGTGTTCATTGGTATTGGCAGCAACGAGTACGCG
ATGCTCAACGGGGTGGGGAGCGCCTCGGCCGCAGGGGATGCCTACATCGCCACGGGCAAT
GACTCGAGCTTCGCCGCGGGCCGGCTGGCCTATCTGCTCCGGTTCCAGGGGCCGACGATG
AGCTTGAACACCGCGTGCTCCTCTTCGCTGGTGGCCGTGCACCTGGCCTGCCAGAGCTTG
CGCGCCGGTGAGAGCAACCTGGCGCTGGCGGGTGGCGTCAACATGACGCTCGCGCCGCAC
TCGACCATCTACCTCGCGCAGCTTCGTGCCTTGTCTCAGGATGGGCGGTGCAAGACCTTC
GATGCCTCCGCGGACGGCTACGTGCGCAGCGAGGGTTGCGGCATCGTGGTTCTCAAGCGC
CTGTCCGATGCGAAACGGGATGGGGATGACGTCCTGGCCGTCATCCGCGGCTCGGCGGTC
AACCACGATGGTCCGAGCAGTGCGCTCACGGTGCCCAATGGCGATGCCCAGCAGCAGGTT
CTCCGGGCGGCCCTGGCCAACGCGGGGGTTGCGCCTGCGGACGTGGATTACATCGAGGCG
CATGGAACGGGCACGTCACTCGGCGATCCCATCGAGGTCCAGGCTCTGGCCAACGTGCTC
GGCCAGGGACGTACGTCCGAACAGCGGCTGCTGATCGGCTCGGTGAAGACCACCATTGGT
CACCTGGAGGCAGCGGCGGGCATCGCCGGTCTCATCAAGGTCGTCCTCGCCCATCGGCAT
GGGGTGGTTCCGCCGCACCTGCACCTCAAGAAGCTCAACCCGCACATCGAGCTGAATGGC
TTCCCGCTGGACATCCCGACACAGGTCACTCCGTGGCCGGAGCGTGCGCGTCCTCGGATC
GCTGGCATCAGCGCCTTTGGCTTGAGCGGCACCAATGCGCACGTCCTCGTGGAGGAGGCG
CCCGCTCCCGAGCCTCGCGCGGAACAGGCGGAGCGGAGCCTGCACGTGCTTGCGCTCTCG
GCGAAGACGAAGGGTGCGCTCACGCAACTCGCGGCTCGGGTGGGTGAGTACCTCGCCGAG
CAGCCAGAGCAGAAGCTCGCGGATGTCTGCCATGCGGCGAACACGCAGCGCACTTGGTTC
TCGCATCGACTCGCGCTCGTCGTGGAGTCGGTGGAGCAGACCCGGGAGCGGCTGTTGGCG
TTCGCGCGAGGGGAGGAAGTCCCTCGGCTGGCCCAGAACCGCGTCGAAGGCGAAGATCCC
AAGGTCGTCTTCGTATTCACGGGGCAGGGCGCGCAGTACGCGGGCATGGGCCGGGAGCTG
TACGAGACCGAGCCTGTCTTCCGTGCGGCCTTGGATCGGTGCAATGCATTGATCGAGGGC
AAGTGGGCCGAGTCCCTCCTCTCGGTGATGCACGGCACGGGCTCGCGGATTGACGACACC
GAGTACACCCAGCCGGCCTTGTTCGCGTTGGAGTACGCCCTGGCGGAGCTGTGGCGTTCC
TGGGGCGTCGAGCCCTGGGCGGTGTTGGGCCACAGCGTCGGTGAGTACGTGGCCGCCTGC
GTGGCGGGGGTGATGGAGCTCGAAGAAGCCCTCGGTCTCATCACCGAGCGTGCGCGGCTC
ATGCAAGCACTGCCGCGCAATGGCGAGATGGTGGCCGTCTCCGCGAGTGAGGCGCAGGTC
CAGGAAATGCTGGCTCCTTATGCGGATCGGGTTTCGATCGCGGCGGTCAATGGCCCGGCG
GACACCGTGATTTCCGGTGAGAGGGAGGCGGTGGAAGCCATCTCCGCTTCGTTGCAGGCC
AAGGGCGTCAAGGCCCGGCGGCTTACCGTGTCCCACGCGTTCCACTCTCCGCTCATGGAC
CCCATGCTGGATGCGTTCGAGAAGGCGGCTGGCAAGATCGCCTTCCGTGCGCCTCGCCTC
CACCTGGCCTCCAACGTCACGGGCCAGCTCCTCGGAGATGGCGCCGTGCTCGACGCCGCA
TACTTCCGCCGCCACGTGCGCGAGGCCGTGCGCTTCCACGACGGGCTGAAGGCACTTCGG
GCGCTCGGTGGCACCGTGTTCGTGGAGGTCGGCCCGCACCCGACGCTCACCAGCATGGCG
CTGAAGGGGCTGGGGGATGATGCGGGCACTTGGTTACCCTCGCTGCGCAAGGGTCAGCCC
GAGCAGCCGCAGATTCTTTCCAGCCTGGGCGCACTCTACACCCAGGGCGTGGCGGTGAAC
TGGATCGCGCTGAACGGCGAGCGCCACCGGTCGCCCGTTGCGCTCCCTGTCTACCCGTGG
CAGCACCAGCGGCACTGGCTGGAAACCGCCAAGACGCCGCGTCCCGTCGCACCGACCACG
TGTGCGCAGTCGCTCGTGGGACAGCGTGTGCGCTCGCCCTTGAACAAATCGATCGTCTTC
GAGGGCCGCTACAGCGCGCAGTCGTTGCCCTTCTTGGATGACCACCGACTCTACGGAACG
GTCGTCGTGCCCGGCTCGTGCCACATCGCGCGCATCATCGCGACCGCTGCTCAGTCGTTC
GGGACGGGGCCGTACACCATCGAAAAGTGCCTCTTCTCGCAGCCCATCGTGCTCGCGGAC
GACGAGGAGCAGCTCGTCCAACTCGTTCTTGCTCCGAAGGGGCAGGGTCGGTACGACTTC
GAGATCTACAGCCTCTCCCCGACCGCCGATGAGGAGACCGAGGGGTGGTTGCTGAATGGC
ACGGGCACGCTGCAAGTGGGTGGAGACGGGCACTCGCGTCCGGAGCCCATCTCGCGACAG
GACATCGAAGCGCGTTGCACGCGCTTGATGGAGTCGGGTCTCTACGAGAAGAATTGGGAC
ATCGGGTTTAACCTCGGCCACGCATTCCGGTGGATCGAGCGCGTCCAGAGTGGCGGGCGC
GAGGCGCTCTGCCAGATGCGTCTGCCGACGGAGCGGGATGACCGGGGGCTGTACGTTCAC
CCGGGCTTGGTCGACTCCTTCCTGCAGGCGATGGGCACGGATCTCATCCGCGAGGACGCG
CAGTTGAGCACCGTCTACGTACCCATCTCCGTGGAGCGCTTCCGCTTCTACGAGCAGCCG
ACGGGTCCCGTGTGGGCCTACGCTGTCCGCCGGGACGCGGAAGAGGCCGTGGGCGAGGTG
ATCACCGGCGACGTGTACGTGGTCAACGCCGAGGGGCGGGTGCTCATCGAGATCGAGGGG
TTGAAGCACAAGCGTGCCCCGCGAGAGGCCCTGATGGCAGTGTTGCGCCATGGCCAGCGC
GATACGCTCTACGAGCTTGGGTGGAAGCGCCAACCGCTGCCCGAGGGCGTGCCTGGCTCT
GGTCGCTGGATCGTGTTCGCGGACGAGACGGGCACCGGTGAGGCGCTCGCGGAGCGGCTC
CTGAAGAGTGGTTGTCGCCCTGTGCTGGTCCGGCCGGGAGAGGCGTTCGCCCGTCAGGAC
GGAGACCGTTTCACCCTCGACGCACAGCGCGCCGAGGACTACGCGCGGCTGCTCAAGGAA
GCGGTGCCTTCGGGCGAATCGCTTGGGGGCGTTGTCCACCTCTGGGCGATGCGCGGGGCC
CACGGAAATGACGTGGAGTCGCTGCACGCGGCGCACCAGTTGGGTGGCGGCAGCGCGCTG
CATCTGGCCAAGGCCGTGGCGAGCTTCCCCTCTGCCGCGCGCCTCTGGCTGGTGACCCGT
GGCGCTCGGGCGCTCCCATCTCATTCAGGGCCACTGGCGCTGAATCAGGTTCCTGTCTGG
GGCTTGGGGGTCGTCTTTTCGCAGGAGCATCCGGAGCGATGCGGTGCGCTGATCGACCTC
GATCCCTCTGCTTCTGGAGAGGATGCGACGGCGATCTGGCGCGAGCTCAGCGCCGCTGAT
GGCGAGCGGCAGGTGGTGATCCGTGAGGGCCAGCGTCACGTCGCTCGCATTCGCGCATCG
CGGGACGAGCAGCGAAACGCGGCGCAGCGGTTGCGGCCGGACGCGAGCTACCTGCTTACG
GGTGGACTCGGTGGGCTGGGCCTCTCGCTGGCTCGGTGGATGGTGGATCAAGGGGCACGG
AACCTCGTGCTCATCGGACGCGGTGCGGCCAAGCCAGAGGCGCAGGAGACCCTCCGCACC
CTGGAGGCTGCGGGCGCGAAGGTTCTTGTCCTCCAGGCGGATGTGTCGAAGCAGGCAGAC
GTCCGCCGTACCCTCGAGGAAGCTGAGAAGCTGGCGCCTCTGCGCGGCGTGGTCCATGCC
GCGGGCGTCCTGGACGATGGTGTCCTTCTGCAGCAGGACTGGGAGCGCTTCTCCCGGGTG
TTCGCACCCAAGGTGGATGGCGCATGGCATCTCCATGAGTTGACGAAGGACAAGGAGCTC
GACTTCTTCGTCCTGTACTCGTCAGCGGCGACGTTGCTGGGCCCGCCGGGACAGGGAAGC
TATGCGGCGGCCAATGCCTTCCTGGACGCGCTGGCGCATCACCGGCGCTCTCAGGGGCTG
CCGGCACTGAGCATCAACTGGGGCCCCTGGGCCGAAGTGGGCATGGCCGCGCAGCATGCG
TCCCGCTTCCAGACACAGGGCATCGAGGCATTCTCTCCGGAAGCGGCGCTGAAGGCGTTC
AGCCAGGCGCTGAGTCGAGCGCAGCCGCAACTCACCCTCATGCAGGTGCAGTGGTCGCGC
TACCTCGCGCAGTACCCGAGGGGCGCGGCACCGACCGTGCTCGCTGAAGTCTCGGGCCGG
GCGGTGGCCGAGCCCGAAGCCAACGGGCACTCGGCTTCCGAATTCCGGCGTCGGCTCGAG
TCGGCGGAGCCACGCCAGCGCTTGCCGTTGCTGTTGGAGCACGTGCAGGGCGAGGCGGTG
CGGGTGCTCGGCCTGGATGCATCGGCGTCGTTGGAGCCTCGGCAGCGGTTGTTCGAGGTG
GGCATGGACTCGCTGATGGCGCTGGAGCTTCGCAACCGTCTGCAGACCACTGTGGGGGCG
TCGCTGCCGTCGACCCTGGTCTTCGATTACCCGACGGCCGAGGCGATCGCGAACTACCTG
CTGGGGGAAGCCCTGGGGTTGGAGAAGCAATCGGCAGGAAACGCGCAAGGAGAAGTCCAG
GACACGGCGCTTCTCGAGCGCATCATGGAGCTATCGCCGGATGAGCTTGCCGCCTCCCTG
GAGGCGAAGCTCTCCGCCCTGATGGAAGAAGGATCATGA
[4] KS36..405
[4] AT559..877
[4] malonyl-CoA not conserved HAFHS750..754
[4] DH922..1096
[4] KR1466..1645
[4] ACP1739..1812
[5] KS1851..2217
[5] AT2372..2689
[5] malonyl-CoA not conserved HAFHS(H->Y)2563..2567
[5] KR2988..3181
[5] ACP3281..3351
[6] KS3374..3749
[6] AT3903..4219
[6] malonyl-CoA4092..4096
[6] DH4263..4432
[6] KR4795..4973
[6] ACP5071..5141
[4] KS106..1215
[4] AT1675..2631
[4] malonyl-CoA not conserved HAFHS2248..2262
[4] DH2764..3288
[4] KR4396..4935
[4] ACP5215..5436
[5] KS5551..6651
[5] AT7114..8067
[5] malonyl-CoA not conserved HAFHS(H->Y)7687..7701
[5] KR8962..9543
[5] ACP9841..10053
[6] KS10120..11247
[6] AT11707..12657
[6] malonyl-CoA12274..12288
[6] DH12787..13296
[6] KR14383..14919
[6] ACP15211..15423

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR001227 Acyl transferase domain (Domain)
[555-682] G3DSA:3.40.366.10 [751-868] G3DSA:3.40.366.10 [2364-2495] G3DSA:3.40.366.10 [2563-2679] G3DSA:3.40.366.10 [3896-4024] G3DSA:3.40.366.10 [4092-4207] G3DSA:3.40.366.10
G3DSA:3.40.366.10   Ac_transferase_reg
IPR002198 Short-chain dehydrogenase/reductase SDR (Family)
[1466-1632] 5.40000000000002e-61 PF00106 [2989-3168] 9.29999999999998e-51 PF00106
PF00106   adh_short
IPR006162 Phosphopantetheine attachment site (PTM)
[1770-1785] PS00012 [3309-3324] PS00012 [5099-5114] PS00012
PS00012   PHOSPHOPANTETHEINE
IPR009081 Acyl carrier protein-like (Domain)
[1746-1811] 3.7e-11 PF00550 [3284-3350] 5.8e-12 PF00550 [5076-5140] 1.4e-10 PF00550
PF00550   PP-binding
[1736-1864] 2.60000517657733e-25 SSF47336 [3274-3390] 1.70000295590054e-21 SSF47336 [5064-5143] 1.10000150671642e-18 SSF47336
SSF47336   ACP_like
[1744-1815] 1.40000000000001e-55 G3DSA:1.10.1200.10 [3280-3352] 1.40000000000001e-55 G3DSA:1.10.1200.10 [5071-5142] 1.40000000000001e-55 G3DSA:1.10.1200.10
G3DSA:1.10.1200.10   ACP_like
[1739-1812] PS50075 [3281-3351] PS50075 [5071-5141] PS50075
PS50075   ACP_DOMAIN
IPR013968 Polyketide synthase, KR (Domain)
[4795-4973] 6.70000000000005e-75 PF08659
PF08659   KR
IPR014030 Beta-ketoacyl synthase, N-terminal (Domain)
[36-280] 1.29999999999998e-93 PF00109 [1851-2091] 1.79999999999997e-92 PF00109 [3374-3624] 1.69999999999998e-96 PF00109
PF00109   ketoacyl-synt
IPR014031 Beta-ketoacyl synthase, C-terminal (Domain)
[288-405] 3.2e-43 PF02801 [2099-2217] 9.69999999999989e-43 PF02801 [3632-3749] 1.29999999999998e-46 PF02801
PF02801   Ketoacyl-synt_C
IPR014043 Acyl transferase (Domain)
[559-877] 2.50000000000001e-90 PF00698 [2372-2689] 6.60000000000002e-94 PF00698 [3903-4219] 1.39999999999997e-75 PF00698
PF00698   Acyl_transf_1
IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase (Domain)
[557-862] 8.70005082121737e-67 SSF52151 [2370-2672] 8.29994113369276e-73 SSF52151 [3901-4202] 5.29997329885557e-73 SSF52151
SSF52151   Acyl_Trfase/lysoPlipase
IPR016036 Malonyl-CoA ACP transacylase, ACP-binding (Domain)
[685-750] 2.09999806691534e-14 SSF55048 [2497-2562] 2.79999889404114e-14 SSF55048 [4026-4091] 7.00000734129907e-20 SSF55048
SSF55048   Malonyl_transacylase_ACP-bd
IPR016038 Thiolase-like, subgroup (Domain)
[36-291] G3DSA:3.40.47.10 [292-458] G3DSA:3.40.47.10 [1851-2103] G3DSA:3.40.47.10 [2105-2269] G3DSA:3.40.47.10 [3376-3636] G3DSA:3.40.47.10 [3637-3803] G3DSA:3.40.47.10
G3DSA:3.40.47.10   Thiolase-like_subgr
IPR016039 Thiolase-like (Domain)
[29-404] 1.19999063421924e-101 SSF53901 [1840-2269] 5.39997012872478e-103 SSF53901 [3366-3748] 1.3000049540733e-103 SSF53901
SSF53901   Thiolase-like
IPR016040 NAD(P)-binding domain (Domain)
[1251-1357] 1.29999999999998e-61 G3DSA:3.40.50.720 [1465-1651] G3DSA:3.40.50.720 [2777-2886] 3.70000000000004e-71 G3DSA:3.40.50.720 [2990-3183] 3.30000000000002e-118 G3DSA:3.40.50.720 [4796-5006] G3DSA:3.40.50.720
G3DSA:3.40.50.720   NAD(P)-bd
IPR018201 Beta-ketoacyl synthase, active site (Active_site)
[193-209] PS00606 [2004-2020] PS00606 [3537-3553] PS00606
PS00606   B_KETOACYL_SYNTHASE
IPR020801 Polyketide synthase, acyl transferase domain (Domain)
[561-859] 3.99998544139406e-116 SM00827 [2374-2671] 2.39999798157263e-110 SM00827 [3905-4199] 4.40002866058555e-128 SM00827
SM00827   PKS_AT
IPR020806 Polyketide synthase, phosphopantetheine-binding domain (Domain)
[1744-1815] 4.49999046578037e-23 SM00823 [3282-3354] 7.19999557654549e-23 SM00823 [5072-5144] 1.10000150671642e-26 SM00823
SM00823   PKS_PP
IPR020807 Polyketide synthase, dehydratase domain (Domain)
[922-1096] 5.50001754266469e-41 SM00826 [4263-4432] 1.90000694315261e-42 SM00826
SM00826   PKS_DH
IPR020841 Polyketide synthase, beta-ketoacyl synthase domain (Domain)
[39-458] SM00825 [1850-2269] SM00825 [3376-3802] SM00825
SM00825   PKS_KS
IPR020842 Polyketide synthase/Fatty acid synthase, KR (Domain)
[1466-1645] 1.20000117458134e-62 SM00822 [2988-3181] 1.40000506907309e-57 SM00822 [4795-4973] 5.20000089003336e-70 SM00822
SM00822   PKS_KR
SignalP No significant hit
TMHMM No significant hit
Myxa_00050 Myxa_00050   Myxa_00070 Myxa_00070
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