Nanch_00100 Nanch_00100   Nanch_00120 Nanch_00120

Nanch_00110 : CDS information

close this sectionLocation

Organism
StrainNS3226
Entry nameNanchangmycin
Contig
Start / Stop / Direction36,429 / 48,299 / + [in whole cluster]
36,429 / 48,299 / + [in contig]
Location36429..48299 [in whole cluster]
36429..48299 [in contig]
TypeCDS
Length11,871 bp (3,956 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category1.1 PKS
Productpolyketide synthase
Product (GenBank)NanA4
Gene
Gene (GenBank)nanA4
EC number
Keyword
Note
Note (GenBank)
  • PKS
Reference
ACC
PmId
[12770825] A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin. (Chem Biol. , 2003)
comment
Nanchangmycin生合成のためのcomplete gene clusterの報告。
（complete clusterと言っているが、同定されたclusterがNanchangmycin生合成に十分かは確認されていない。）

NanA4: PKS
Module 5(KS, ATp, DH, KR, ACP)
Module 6(KS, ATa, DH, ER, KR, ACP)

module 5のKR domainは4つの保存されたactive site残基のうち2つが変更されているためinactive.
module 6のDH domainも保存されたactive site残基が変更されているためinactive.
module 5の DH domainとmodule 6のER domainは、明らかに機能的だが結果としてsilent.

KR6 domainの不活化はC-19にketo基を持ち、4-O-methyl-L-rhodinoseと抗菌活性を失ったNanchangmycin aglyconeを産生した。

close this sectionPKS/NRPS Module

5 methylmalonyl-CoA
6 malonyl-CoA
KS35..409
AT597..918
dh966..1134
kr1476..1653
ACP1728..1798
KS1822..2199
AT2360..2677
dh2724..2889
er3193..3503
KR3513..3693
ACP3798..3868

close this sectionSequence

selected fasta
>polyketide synthase [NanA4]
MSSTEDKLRQYLKRVTVDLGEARARLRKAEQRQHEPIAITSMACRYPGGVTSPETLWELV
DSRTDAIGSFPANRGWNLASLYHPDPDHSGTSYVRDGGFVHDADEFDASFFNISPREALA
MDPQQRLLLETAWELLERAHIDPTALKGTPTGVYTGCGVPGFGTPHIERSAEGFLLTGNA
LSVVSGRIAFTLGLEGPAVTLDTACSSSLVAMHLAVQALRQGECDLALAGGVTVMSTPNV
IVEFSRQRGLSPDGRCKPFATAADGTGFSEGAGLVLLERLSDAERNGHQVLAVIRGTAVN
QDGASNGLSAPNGPSQQRVIRQALANAGLATVEVDAVEAHGTGTTLGDPIEAEALLATYG
QERPEDRPLWLGSIKSNIGHTQGAAGVAGVIKMVMAMRHASLPATLHVDEPTSHVDWDRG
TVRLLTEPVDWPTAPDRPRRAGVSAFGISGTNAHIILEEAGLPTAAEAEAGTAAEAGTDA
GAGTEAGAEDAAPEEATVEPALLGGVAPWVVSARTQEALADQARGLVRAVTDTGAPDAVP
AEVAWSLATTRATFDHRAVVTGTELADLTAALEALATGGEHPHLVRGTALDPQAGPVLVF
PGQGSQWPGMAVGLLDSSPAFATRIAACEQALAPYVDWSLTAVLRGSDTATDPHRVDVIQ
PTLWAVMVSLAGLWQDFGITPAAVIGHSQGEIAAACVAGALSLDDAAKVVALRSQALRAL
AGHGAMASLTLGAEDTARVLTGLGPAAEGVAVAAHNGPRSTVVSGPPDQIATVLAAAEAR
GARTRTIDVDYASHSPHVDRIRDTILAQLADLAPAAPTIPFYSTVTGEPLADTPLDAEYW
FTNLRQPVRFTDTLTTLLDHQHRHFIEASPHPVLTPGIQDAIDDAELPATTIPTLRRDHG
TPHDLADALALAHTTGLAVDWRPWYATTPPATTDLPTYPFQRQRYWSAAGRRTGDVSAAG
LRPVDHPQLSAATGLADGGLLLTGRLPAAGDAGWLGEHEFADVVLVPSTALVEWTLRAAD
EAGCGGVEELTLEVPLTLSAASELRVQVVVDAPDEDGRRAVRVSSQPAVDTPDRADGQDT
WTCHATGTLMAAAAAGTELAGAWPPAGAEPVDLTNLYARAEAAGYRYGPTFQGVQAVWRH
GADLLAEVALDQGAEEGGDEFGIHPALLECALHPVALTDTPHDDTPLGDADTDGPLWLPF
AWNGVSLHAGGATSVRVRIGQRGQTDTEGRELTVVVADPTGAPVLTVDSVALRPADGDWL
KAAERRSTAALFTVEWTPLPPQDSRPEPVEAEDGWATLGASGPGHHYADLAALLSAADGA
EPAPPVVLASVTPTADTGADSEADTDLATVRRTLGLIQEWLAEPGLRDSRLVLITSGATS
VGDGDGPVEPGSAAVFGLVQAVQAEHPDRFMLVDVGADADADGDGDGGETLADAVRRAIA
ADEPQIAVRSGEVSVPRLLRAAARPDEGTAVELSGGTVVVSGAMDHVSGGAIAEQLVRAY
GAERLLLLSHPDEQAPDLAERLTALGAAVEVAVVDIADRAALAEVLASVPDSHPLVGVVH
LAGAADEGPVESWNDGRLSRAWAPRATGAWQLHTLTQDLPLRMFVVCSAAADVTGGPGRA
GYAAANAHTDALIAHRRAAGLPGTGLVWALEEEATADASRLFDAAFHAVQPLVVAADLDT
ARLGPSAPALLRALVRPARRRAAERQSAAHALTSRLAGLDNSGQRELLLDVVRQMAAVVL
GHSSDTAIRAEAAFKELGFDSLTAVGLRNRLVDATGLRLPSTLVFDYPTPRALADHLLQL
VTSTAPTTSLPVGPARAAGADDEPIAVVAMACRFPGDVTTPEGLWDLVAAGENIRGPFPT
NRGWDLANLFHPDPEHPGTTYASQGAFIYDADGFDAAFFGINPREALAIDPQQRLILETA
WEALERAGIDPHTLKESLTGVYTGVIYHDYAAGLPASDPRLDGYTMLSSIGSIISGRVAY
TLGLQGPAVTVDTACSSSLVAMHLAAQALRQGECDLALAGGVTVMATPDPFTGFSRQRGL
APDGRCKPFAAAADGTSLSEGAGLVVLERLSDARRNGHQVLAVLRGSAINQDGASNGLTA
PNGPSQQRVIGQALANAGLGPADIDAVEAHGTGTTLGDPIEAQALLATYGQHRADDRPLW
LGSVKSNIGHTQAASGVVGVIKMIMAMRHGRLPASLHIDEPSPHIDWTSGNVQLLTEAID
WPEADRPRRAGVSSFGASGTNAHVILEEAPPPPDPAPEPAAAPAIAGGVVPWPLSARDEQ
ALREQASALAEHLGTDDRASVADVGWSLATTRAMFERRAVIVGEGREEMAAALEALADGS
PHPGLSTLGGTASDTPGKTVWLFSGQGSQRPGMGADLYRRFPVFAEAFDGVRALLDPHLD
HPLADVVFATDPGHGDLIHHTTYTQAGLFALHIALARLLGDMGLAPDAVAGHSIGEISAA
HLAGVLSLEDAAQLVAARATLMGGLPSGGAMATVNADEQEITATLADYPDLAIAAMNTPA
HTVVSGPADQVAALTAAWRERGRKTRALPVSHAFHSPQMEPILVPFTEAIGHLAFHPPRI
PLISNLTGEPAGEDIATPDYWARHIRRPVHFHQSITHLAEDTAVFLELGPAPVLTHAVHH
TLPEETTATALATLTGKQPDVPALAHSLAALHTSHAPVDWTPWFRTDPAPRTVGLPTYRF
QRRPYWIAPRVSGGATPGGTGLDHPLLDTAAALADGGMVLTGSVPPADHDSWLTERAIAG
TVVLPGTALLELALRCAEDTRSPHVEELLLHHPLTLHPTAHLDLQVVIGAADDDARRTLH
LYTRPQSDSSAEWTRHATATLTGEPTDDRPPAEGEAAWPPAGAEPVDLTGFYDRAASNGY
AYGPSLRGLQALWRHGEDLLADIALPMADDSTDTLVLHPALLDSALHPLLAVMDTSGDQV
WLPFSWSGVTLHATGATHARVRVTPHDDHEHRIALTDTAGRPILTANAVAVRPTRLEAPQ
QPLSEGLFSLEWTPVSTLADRSDAAAPTPGVVLAKAPVAEGEGGELEAVQRALTLVQDWL
AEPRPDDARLVVMTRDAVAVDGEAHIDPVAAAVWGLIRSAQTENPGRFVLLDRDLDTELD
TDPVLGPDALAEADGRVAEAVRCALDLDESQVALRGGRVLVPRLVRATASATLPGPVDRR
NWRLEAATPAGAASLDAVAPVPFPEAEEEPAAGRVRIEVRAAGVTFRDVLIATGGVPDET
RLGGEGAGVVLEVGPDVTDVAPGDRVMGVFDGAFGRVADADARMVTRMPRTWDFTRAAGV
PVAFLTAWYGLVELADLRAGESVLIHAATGGVGTAAVQIARHLGADAYATADPAEHHVLE
AMGIDEAHRASSRDLDFENAFRAATGGRGVDVVLNSLTGDHIDDRTDASLRLLAEGGRFL
DPGRADARDPEQLAKDFPAVDYRVYDLVPDAGPERVQPMLAALVALFDEGVLAPLPVRAW
PLARARQALRHMSRAEHTGKLVLTVPPALDPDGTVLITGGTGVLAGLVAEHLVTTHHITH
LHLLSRRGPDAPGATDLATRLAELGATVHITAADASDPGALRRVVDAIDPDHPLTGVVHT
AGIVEDAVVTSQTPDTLRRVWTAKATSAANLHQATKHLPLAMFTLYSSVSGTLGNPGQAN
YAAANAYCDALAAQRQHAGLPATSIAWGLWSTASDITGQLSQADVARMGRAGVRALATEH
ALALFDAAHRQGDPQLVALNLDVPALAAQPVAILPAALRGLATRSGGTTRRAAAAVQRPD
DWTRRLAGLPEAEQRQQLLTLVRGNAATVLGHADSERVREEAPFKDLGFDSLTGVELRNR
LSAATGLRLPAALVFDFPSAKSLADYLRGRLVADGGSAAQAGVDPVLGELARLESTLSAL
DLPEADARAVTDRLEGLLAQWKAASAPPAEDNAADRLTLATADEVLAFIDNELGTS
selected fasta
>polyketide synthase [NanA4]
ATGTCGTCCACGGAAGACAAGCTGCGCCAGTACCTCAAGCGGGTCACCGTCGACCTGGGC
GAGGCCCGAGCGCGCCTGCGCAAAGCGGAGCAACGCCAACACGAGCCCATCGCCATCACC
TCCATGGCCTGCCGCTACCCCGGCGGTGTCACCTCCCCCGAAACCCTGTGGGAGCTGGTC
GACAGCCGCACCGACGCCATCGGCTCCTTCCCGGCCAACCGCGGCTGGAACCTGGCCTCC
CTCTACCACCCCGACCCCGACCACTCCGGCACCAGTTACGTCCGGGACGGCGGCTTCGTC
CACGACGCCGATGAATTCGACGCCTCCTTCTTCAACATCAGCCCGCGCGAAGCCCTCGCC
ATGGACCCGCAGCAGCGGCTCCTCCTCGAAACCGCCTGGGAACTCCTCGAACGCGCCCAT
ATCGACCCCACGGCCCTCAAGGGCACCCCCACCGGGGTCTACACGGGCTGTGGTGTGCCC
GGTTTCGGCACACCACATATCGAGCGGAGCGCCGAGGGCTTCCTGCTGACCGGCAACGCG
CTCAGCGTGGTGTCCGGCCGTATCGCCTTCACCCTCGGCCTGGAGGGCCCGGCGGTCACG
CTGGACACGGCGTGCTCGTCCTCGCTGGTCGCGATGCACCTGGCGGTCCAGGCACTGCGG
CAGGGCGAATGCGACCTGGCGCTGGCCGGCGGGGTGACGGTCATGTCGACCCCGAACGTG
ATCGTCGAGTTCTCCCGGCAGCGCGGCCTGTCCCCGGACGGGCGGTGCAAGCCGTTCGCC
ACGGCGGCCGACGGCACGGGCTTCTCCGAGGGCGCGGGCCTGGTGCTGCTGGAGCGGCTG
TCGGACGCCGAGCGCAACGGGCACCAGGTGCTCGCCGTCATCCGGGGTACGGCCGTCAAC
CAGGACGGCGCGAGCAACGGGCTGAGCGCCCCCAACGGACCCTCGCAGCAGCGGGTGATC
CGCCAGGCGCTGGCCAACGCCGGGCTGGCCACGGTCGAAGTGGACGCGGTGGAGGCCCAT
GGCACGGGCACCACGCTCGGCGACCCGATCGAGGCCGAGGCGCTGCTGGCCACCTACGGT
CAGGAGCGGCCGGAGGACCGTCCGCTGTGGCTGGGGTCGATCAAGTCCAACATCGGCCAT
ACGCAGGGCGCCGCCGGGGTCGCGGGCGTCATCAAGATGGTGATGGCCATGCGCCACGCC
TCGCTGCCCGCCACCCTGCACGTCGACGAGCCCACGTCGCATGTGGACTGGGACCGGGGC
ACGGTACGGCTGCTGACCGAGCCGGTCGACTGGCCGACGGCCCCCGACCGGCCGCGCCGG
GCCGGTGTCTCGGCGTTCGGCATCTCCGGCACCAACGCCCACATCATCCTGGAGGAGGCG
GGCCTGCCCACGGCGGCGGAGGCGGAGGCTGGGACTGCGGCTGAGGCTGGGACTGACGCT
GGGGCTGGGACTGAGGCTGGGGCTGAGGACGCCGCACCGGAGGAGGCCACCGTAGAGCCG
GCCCTCCTGGGCGGCGTGGCGCCCTGGGTGGTCTCGGCCCGTACCCAGGAGGCCCTGGCC
GACCAGGCGCGCGGGCTGGTCCGCGCCGTCACCGACACCGGCGCCCCGGATGCCGTGCCC
GCCGAGGTGGCCTGGTCGCTGGCCACCACCCGCGCCACATTCGACCACCGCGCCGTGGTC
ACCGGCACCGAACTCGCCGACCTCACCGCCGCGCTCGAGGCCCTGGCCACCGGCGGTGAA
CACCCCCATCTCGTCCGAGGCACCGCCCTCGACCCGCAGGCGGGCCCGGTCCTCGTCTTC
CCCGGCCAGGGCTCCCAGTGGCCCGGTATGGCCGTCGGGCTGCTGGACTCCTCCCCCGCC
TTCGCCACCCGGATCGCCGCCTGCGAACAGGCCCTGGCCCCGTATGTCGACTGGTCACTC
ACCGCCGTTCTGCGCGGCAGTGACACCGCAACCGACCCGCACCGCGTGGATGTCATCCAG
CCGACCCTGTGGGCCGTCATGGTGTCCCTGGCGGGCCTGTGGCAGGACTTCGGCATCACC
CCGGCCGCCGTCATCGGACACTCCCAGGGCGAGATCGCCGCCGCTTGTGTGGCCGGGGCC
CTCAGCCTCGACGACGCCGCCAAGGTGGTGGCACTGCGCAGCCAGGCGCTACGCGCCCTC
GCCGGCCACGGGGCCATGGCCTCCCTCACCCTCGGCGCCGAGGACACCGCCCGCGTCCTG
ACCGGACTCGGCCCGGCCGCCGAGGGCGTCGCGGTCGCCGCCCACAACGGCCCCCGCTCC
ACCGTCGTCTCCGGGCCACCGGACCAGATCGCCACCGTCCTGGCGGCCGCCGAGGCACGA
GGGGCGCGGACCCGCACCATCGACGTGGACTACGCCTCCCACAGCCCGCACGTCGACCGC
ATCCGCGACACCATCCTCGCGCAACTCGCCGATCTGGCCCCCGCCGCGCCCACCATCCCC
TTCTACTCCACCGTCACCGGCGAGCCGCTGGCCGACACCCCGCTCGACGCCGAGTACTGG
TTCACCAACCTCCGCCAGCCGGTCCGCTTCACCGACACCCTCACCACCCTCCTGGACCAC
CAGCACCGCCACTTCATCGAGGCGAGCCCCCACCCCGTCCTCACCCCCGGCATCCAGGAC
GCCATCGACGACGCCGAGCTCCCCGCCACCACGATCCCCACCCTCCGCCGCGACCACGGC
ACCCCCCACGACCTCGCGGACGCCCTCGCGCTCGCCCACACCACCGGCCTCGCCGTCGAC
TGGCGGCCCTGGTACGCCACCACCCCGCCCGCCACCACCGATCTGCCCACCTACCCCTTC
CAGCGGCAGCGCTACTGGTCGGCGGCTGGCCGCCGGACCGGCGACGTCAGCGCGGCCGGT
CTGCGGCCGGTGGACCATCCGCAGCTGTCCGCCGCGACGGGCCTCGCCGACGGCGGGCTC
CTGCTCACCGGGCGCCTGCCGGCCGCCGGTGACGCGGGCTGGCTGGGCGAGCACGAGTTC
GCCGATGTGGTCCTGGTGCCCAGCACGGCCCTGGTGGAGTGGACACTGCGGGCGGCCGAC
GAGGCGGGCTGCGGCGGCGTCGAGGAGCTGACCCTTGAGGTCCCGCTGACCCTGTCCGCC
GCCTCCGAGCTACGGGTCCAGGTCGTGGTGGACGCCCCCGACGAGGACGGCCGACGCGCC
GTACGCGTCTCCTCCCAACCCGCGGTGGACACCCCGGACCGGGCCGACGGGCAGGACACC
TGGACCTGCCATGCGACGGGCACCCTCATGGCCGCCGCAGCCGCTGGGACCGAGCTGGCG
GGCGCCTGGCCACCGGCCGGTGCCGAACCTGTGGACCTCACCAACCTGTACGCACGCGCC
GAGGCCGCCGGCTACCGGTACGGGCCGACGTTCCAGGGTGTCCAGGCGGTGTGGCGGCAC
GGCGCCGACCTGCTCGCCGAAGTGGCCCTGGACCAGGGGGCCGAGGAGGGCGGCGACGAG
TTCGGCATCCATCCCGCGCTGCTCGAATGCGCCCTTCACCCGGTGGCGCTGACCGATACA
CCGCACGACGATACGCCGCTGGGCGATGCGGACACCGACGGTCCGCTGTGGCTGCCGTTC
GCCTGGAACGGCGTATCCCTGCACGCGGGCGGCGCGACGAGCGTACGGGTGCGGATCGGG
CAGCGGGGGCAGACGGACACCGAAGGCCGTGAGCTGACCGTCGTGGTCGCGGACCCGACC
GGCGCCCCGGTGCTCACCGTGGACTCGGTCGCGCTGCGGCCCGCCGACGGCGACTGGCTG
AAAGCCGCGGAACGGCGTTCCACGGCCGCGCTGTTCACGGTGGAATGGACACCGCTGCCG
CCCCAGGACAGTCGGCCCGAGCCGGTCGAGGCCGAGGACGGCTGGGCGACACTCGGCGCC
TCCGGCCCCGGGCACCACTACGCCGACCTGGCCGCGCTGCTGTCGGCGGCGGATGGCGCA
GAGCCCGCGCCGCCCGTGGTCCTCGCCTCCGTAACTCCGACGGCCGACACCGGGGCCGAC
TCCGAGGCTGACACGGATCTGGCCACCGTACGGCGCACGTTGGGGCTCATCCAGGAGTGG
CTGGCGGAGCCGGGGCTACGGGACTCCCGGCTGGTGCTGATCACCTCCGGCGCGACCTCG
GTCGGCGACGGCGACGGGCCGGTGGAGCCGGGGAGCGCTGCTGTGTTCGGCCTGGTTCAG
GCGGTCCAGGCCGAACACCCGGACCGCTTCATGCTGGTCGACGTGGGCGCCGACGCGGAC
GCGGACGGTGACGGAGACGGTGGCGAGACGTTGGCCGATGCCGTACGCCGGGCCATCGCC
GCGGACGAACCGCAGATCGCGGTCCGTTCGGGCGAGGTGTCGGTCCCCCGCCTGCTGCGC
GCCGCCGCCCGGCCCGACGAGGGCACGGCGGTCGAGCTGTCCGGCGGTACGGTGGTGGTG
TCGGGCGCGATGGACCATGTGTCCGGCGGCGCGATCGCCGAGCAGCTGGTACGTGCGTAC
GGAGCCGAACGTCTGCTGCTCCTCTCCCACCCGGACGAGCAGGCTCCCGACCTGGCCGAG
CGGCTGACGGCGCTGGGCGCGGCGGTTGAGGTGGCGGTGGTCGATATCGCCGACCGCGCC
GCTCTGGCGGAGGTTCTGGCGTCCGTACCGGACAGCCACCCGCTGGTGGGCGTGGTGCAT
CTGGCGGGGGCGGCCGACGAGGGGCCAGTGGAGTCGTGGAACGACGGGCGACTGTCGCGG
GCGTGGGCGCCGCGGGCCACCGGGGCGTGGCAGCTGCACACCCTCACCCAGGACCTGCCG
CTGCGGATGTTCGTGGTGTGCTCCGCCGCCGCTGACGTCACGGGCGGCCCCGGCCGGGCC
GGATACGCCGCCGCCAACGCCCACACCGACGCCCTGATCGCCCACCGGCGCGCCGCCGGG
CTCCCGGGCACGGGTCTGGTCTGGGCCCTGGAGGAAGAGGCCACCGCCGACGCCTCGCGC
CTGTTCGACGCGGCGTTCCATGCCGTACAGCCGCTGGTCGTGGCCGCGGACCTGGACACC
GCCCGGCTGGGCCCCTCGGCCCCCGCGCTGCTGCGTGCCCTGGTCCGGCCGGCCCGGCGC
CGCGCCGCGGAACGGCAGTCGGCGGCCCACGCCCTGACCTCGCGCCTCGCCGGTCTCGAC
AACTCCGGACAGCGCGAACTGCTGCTGGATGTGGTGCGCCAGATGGCCGCCGTGGTCCTG
GGCCACTCCTCCGACACGGCGATCCGGGCCGAGGCCGCCTTCAAGGAGCTGGGCTTCGAC
TCCCTCACGGCCGTCGGGCTGCGCAACCGCCTTGTCGACGCCACCGGGCTGCGGCTGCCC
TCGACCCTGGTCTTCGACTATCCGACCCCCCGGGCCCTGGCCGACCACCTCCTCCAGCTC
GTGACCAGCACCGCGCCCACCACTTCGCTCCCGGTGGGGCCGGCGCGGGCCGCCGGCGCG
GACGACGAGCCCATCGCCGTGGTGGCGATGGCATGCCGCTTCCCCGGCGATGTGACCACG
CCCGAGGGGCTGTGGGACCTGGTCGCGGCGGGAGAGAACATCCGCGGCCCGTTCCCCACC
AACCGCGGCTGGGACCTGGCCAACCTCTTCCACCCCGACCCCGAACACCCCGGCACGACC
TACGCCTCGCAAGGCGCGTTCATCTACGACGCCGACGGCTTCGACGCCGCGTTCTTCGGC
ATCAACCCCCGCGAGGCGCTGGCCATCGACCCCCAGCAGCGCCTGATCCTGGAAACCGCC
TGGGAAGCCCTCGAACGCGCCGGTATCGACCCACACACCCTCAAGGAGAGCCTGACCGGC
GTCTATACCGGCGTCATCTACCACGACTACGCCGCCGGTCTGCCCGCGAGCGACCCCCGG
CTGGACGGCTACACCATGCTGTCCAGCATCGGCAGCATCATCTCCGGCCGGGTGGCGTAC
ACCCTCGGCCTGCAGGGCCCGGCCGTCACCGTGGACACCGCCTGCTCCTCCTCCCTGGTG
GCCATGCACCTCGCCGCCCAGGCGCTCCGCCAGGGCGAATGCGATCTGGCGCTCGCGGGC
GGCGTGACCGTCATGGCCACCCCCGACCCGTTCACCGGGTTCTCGCGCCAGCGCGGACTG
GCCCCGGACGGGCGGTGCAAGCCGTTCGCCGCCGCCGCCGACGGCACCAGCCTGAGCGAG
GGAGCCGGGCTCGTCGTGCTCGAACGGCTCTCCGACGCCCGCCGCAACGGCCATCAGGTG
CTCGCCGTACTGCGCGGATCCGCGATCAACCAGGACGGCGCGAGCAACGGGCTGACCGCC
CCCAACGGCCCCTCCCAGCAACGCGTCATCGGCCAGGCACTCGCCAACGCCGGCCTCGGC
CCCGCCGACATCGACGCCGTCGAGGCCCATGGCACCGGCACGACGCTGGGCGACCCCATC
GAGGCCCAGGCCCTGCTGGCCACCTACGGCCAACACCGCGCCGACGACCGGCCGCTGTGG
CTCGGCTCGGTCAAGTCCAACATCGGCCACACCCAGGCCGCCAGCGGGGTCGTCGGCGTG
ATCAAGATGATCATGGCGATGCGCCACGGCCGGCTGCCCGCCAGCCTCCATATCGACGAA
CCCAGCCCGCATATCGACTGGACCAGCGGAAACGTCCAGCTCCTCACCGAAGCCATCGAC
TGGCCCGAGGCCGACCGGCCCCGCCGCGCCGGTGTGTCCTCCTTCGGCGCCTCCGGTACC
AACGCTCATGTGATCCTGGAAGAGGCGCCCCCACCGCCCGATCCCGCGCCCGAACCGGCC
GCCGCGCCCGCCATCGCGGGCGGCGTGGTGCCCTGGCCGCTGTCGGCGCGGGACGAGCAG
GCGCTGCGCGAGCAGGCCTCGGCGCTCGCCGAGCACCTGGGGACCGACGACCGTGCGTCT
GTCGCGGACGTGGGATGGTCCTTGGCCACGACACGGGCGATGTTCGAGCGGCGGGCCGTG
ATCGTCGGGGAGGGCCGCGAGGAGATGGCCGCCGCCCTGGAGGCGCTGGCCGACGGGTCC
CCCCACCCCGGCCTGTCCACCCTCGGTGGCACCGCTTCGGACACACCAGGGAAGACGGTG
TGGCTGTTCTCCGGACAGGGCAGCCAGCGCCCCGGCATGGGCGCCGACCTCTACCGGCGT
TTCCCCGTCTTCGCCGAGGCCTTCGACGGGGTCCGCGCGCTCCTGGACCCCCACCTCGAT
CACCCGCTCGCCGACGTGGTCTTCGCCACCGACCCCGGACACGGCGACCTGATCCACCAC
ACCACCTACACCCAGGCCGGGCTCTTCGCCCTCCACATCGCCCTCGCCCGCCTGCTGGGC
GACATGGGCCTGGCGCCCGACGCGGTCGCCGGACACTCCATCGGTGAGATCAGCGCCGCC
CACCTCGCCGGTGTGCTCTCCCTGGAGGACGCCGCCCAACTCGTCGCCGCCCGCGCCACC
CTCATGGGCGGCCTCCCGTCCGGCGGCGCCATGGCCACCGTGAACGCCGACGAACAGGAG
ATCACCGCCACCCTGGCCGACTATCCCGACCTGGCCATCGCCGCGATGAACACCCCCGCA
CACACCGTCGTCTCCGGCCCCGCCGACCAGGTCGCCGCCCTCACCGCCGCCTGGCGGGAG
CGAGGCCGCAAGACCCGCGCCCTCCCGGTCTCCCACGCCTTCCACTCGCCCCAGATGGAG
CCCATCCTCGTCCCCTTCACCGAGGCCATCGGCCACCTGGCCTTCCACCCGCCCCGCATC
CCGCTCATCAGCAACCTCACCGGCGAGCCCGCGGGCGAGGACATCGCCACACCCGATTAC
TGGGCCCGCCACATCCGCAGGCCCGTCCACTTCCACCAGAGCATCACCCACCTCGCCGAG
GACACGGCCGTCTTCCTGGAGCTGGGCCCCGCTCCGGTACTGACCCACGCCGTCCACCAC
ACCCTCCCCGAGGAGACCACAGCCACCGCGCTCGCCACCCTCACCGGTAAGCAACCCGAC
GTGCCCGCCCTGGCCCACAGCCTGGCGGCGCTGCACACCAGTCACGCCCCGGTGGACTGG
ACGCCCTGGTTCCGCACCGATCCGGCCCCCAGGACCGTGGGCCTGCCCACCTACCGCTTC
CAGCGCCGGCCCTACTGGATCGCCCCCCGCGTCTCCGGCGGCGCCACCCCCGGCGGTACC
GGCCTGGACCACCCGCTGCTGGACACCGCGGCGGCTCTGGCGGACGGCGGCATGGTGCTC
ACCGGGAGCGTCCCTCCGGCCGACCACGACAGCTGGCTCACCGAGCGCGCCATCGCGGGA
ACCGTCGTGCTGCCCGGCACCGCCCTCCTCGAACTCGCCCTCCGCTGCGCCGAGGACACC
CGCAGCCCCCACGTCGAGGAGCTTCTCCTCCACCACCCCCTCACCCTCCACCCCACCGCA
CATCTCGATCTGCAGGTCGTCATCGGCGCCGCCGATGACGACGCCCGTCGCACCCTCCAC
CTGTACACCCGCCCCCAGTCCGACTCCTCGGCCGAGTGGACCCGGCACGCCACCGCCACC
CTGACCGGCGAACCCACTGACGACCGGCCGCCGGCAGAAGGGGAAGCGGCCTGGCCGCCT
GCCGGCGCCGAGCCCGTCGACCTCACCGGCTTCTATGACCGCGCCGCGTCGAACGGCTAT
GCGTACGGGCCCTCCCTCCGAGGGCTTCAGGCGCTGTGGCGCCACGGCGAAGACCTCCTC
GCCGACATCGCCCTGCCCATGGCCGACGACTCCACCGACACCCTCGTCCTCCACCCCGCA
CTCCTGGACAGCGCGCTCCACCCCCTCCTCGCCGTCATGGACACCTCGGGCGACCAGGTC
TGGCTGCCGTTCTCCTGGAGCGGCGTCACCCTGCACGCCACCGGCGCCACCCACGCCCGT
GTCCGCGTCACCCCCCACGACGACCACGAGCACCGCATCGCTCTCACCGACACCGCCGGC
CGACCGATCCTCACCGCCAACGCCGTCGCCGTCCGGCCGACCCGCCTCGAGGCGCCTCAA
CAGCCGCTGTCCGAAGGGCTGTTCAGCCTGGAGTGGACGCCCGTGTCGACGCTGGCCGAC
CGGTCCGACGCGGCCGCGCCGACGCCGGGGGTGGTCCTCGCCAAGGCGCCGGTCGCGGAG
GGGGAAGGCGGTGAGCTGGAGGCCGTCCAGCGGGCGTTGACCCTGGTACAGGACTGGCTG
GCCGAGCCGCGGCCCGACGATGCCCGGCTGGTGGTGATGACCCGCGACGCCGTCGCCGTG
GACGGGGAAGCGCACATCGATCCCGTAGCGGCGGCCGTCTGGGGCCTGATCCGCAGTGCT
CAGACGGAGAACCCCGGCCGGTTCGTCCTGCTGGACAGGGACCTGGACACAGAGCTGGAC
ACGGATCCGGTCCTGGGTCCCGATGCCCTTGCCGAGGCGGACGGCCGGGTGGCCGAAGCG
GTCCGCTGCGCGCTGGACCTCGACGAGTCGCAGGTGGCGCTCCGCGGCGGCCGGGTTCTG
GTACCCCGGCTCGTCCGCGCGACCGCCTCGGCCACGCTGCCTGGCCCCGTCGACCGGCGG
AACTGGCGGCTGGAGGCCGCGACCCCGGCCGGCGCCGCGTCGCTCGACGCCGTGGCGCCG
GTGCCGTTCCCCGAGGCGGAGGAGGAGCCGGCGGCCGGGCGCGTACGCATCGAGGTGCGC
GCGGCCGGCGTCACCTTCCGCGATGTCCTGATCGCCACCGGCGGGGTGCCCGACGAGACC
CGCCTCGGCGGCGAAGGCGCGGGCGTCGTCCTCGAGGTGGGCCCCGACGTCACCGACGTG
GCACCGGGCGACCGTGTCATGGGCGTCTTCGACGGCGCGTTCGGCCGGGTCGCCGACGCC
GACGCGCGCATGGTGACCCGGATGCCGAGGACCTGGGACTTCACCCGGGCGGCGGGCGTC
CCCGTGGCGTTTCTCACCGCCTGGTACGGCCTGGTGGAGCTCGCGGACCTCAGGGCGGGC
GAGTCGGTCCTCATCCACGCGGCCACCGGCGGCGTCGGCACGGCGGCGGTGCAGATCGCC
CGCCACCTGGGCGCCGATGCCTACGCCACCGCCGACCCTGCCGAGCACCATGTACTGGAG
GCGATGGGCATCGACGAGGCCCACCGCGCATCCTCCCGCGACCTGGACTTCGAGAACGCC
TTCCGCGCCGCCACCGGCGGCCGCGGCGTCGACGTGGTCCTCAACAGCCTCACCGGCGAC
CACATCGACGACCGCACCGACGCGTCCCTGCGCCTGCTGGCCGAGGGCGGCCGCTTCCTT
GATCCCGGCCGGGCCGACGCACGCGATCCCGAACAGCTGGCCAAGGACTTCCCTGCCGTG
GACTACCGCGTCTACGACCTGGTCCCGGACGCCGGGCCGGAGCGCGTCCAGCCGATGCTG
GCGGCGCTGGTGGCGCTGTTCGACGAGGGTGTCCTGGCACCGCTCCCGGTGCGGGCGTGG
CCGCTGGCCAGGGCCCGTCAGGCGCTGCGCCACATGAGCCGGGCCGAGCACACCGGCAAG
CTCGTGCTGACCGTCCCTCCCGCCCTCGATCCCGACGGCACCGTTCTGATCACCGGTGGC
ACCGGCGTGCTCGCCGGCCTGGTCGCCGAACACCTCGTCACCACCCACCACATCACCCAT
CTCCACCTCCTCAGCCGTCGCGGACCCGACGCCCCCGGCGCCACCGATCTGGCGACCCGC
CTCGCCGAACTGGGTGCCACCGTCCACATCACCGCCGCGGACGCCTCGGATCCGGGGGCC
CTGCGCCGGGTCGTCGACGCCATCGATCCGGACCATCCCCTCACCGGCGTCGTCCACACC
GCGGGCATCGTCGAGGACGCCGTGGTCACCTCGCAGACCCCCGACACCCTCCGGCGCGTC
TGGACCGCCAAGGCGACGAGCGCCGCCAACCTCCACCAGGCCACCAAGCACCTCCCCCTG
GCCATGTTCACCCTGTACTCCTCCGTCTCCGGCACCCTCGGCAACCCCGGACAGGCCAAC
TACGCCGCCGCCAACGCCTACTGCGACGCCCTCGCCGCCCAGCGGCAGCACGCCGGCCTG
CCGGCCACCTCCATCGCCTGGGGCCTGTGGTCCACCGCCAGCGACATCACCGGGCAACTC
AGCCAAGCCGATGTGGCACGGATGGGCCGCGCCGGCGTCAGGGCGCTGGCCACCGAACAC
GCGCTGGCGCTGTTCGACGCGGCACACCGGCAAGGCGACCCGCAACTCGTGGCGCTCAAT
CTCGACGTGCCCGCCCTGGCCGCGCAGCCGGTCGCCATCCTCCCGGCCGCACTGCGCGGC
CTGGCCACCCGCTCGGGCGGGACCACCCGGCGCGCCGCCGCGGCCGTGCAGCGCCCCGAC
GACTGGACGCGCCGGCTCGCCGGGCTCCCGGAGGCCGAACAGCGGCAGCAGCTGCTCACG
CTGGTACGCGGCAACGCCGCGACCGTGCTCGGCCACGCGGATTCCGAGCGCGTCCGGGAG
GAGGCCCCGTTCAAGGATCTCGGCTTCGACTCCCTGACCGGCGTCGAGCTGCGCAACCGG
CTCTCGGCCGCGACCGGGCTGCGGCTGCCCGCCGCGCTCGTCTTCGACTTCCCGTCGGCG
AAGTCGCTGGCCGATTACCTGCGCGGCCGGCTGGTGGCGGACGGGGGGTCGGCGGCCCAG
GCCGGTGTCGACCCGGTGCTCGGCGAGCTGGCGAGGCTGGAGTCCACGCTGTCGGCCCTC
GATCTGCCCGAGGCCGACGCGCGGGCGGTGACAGATCGGCTTGAGGGTCTGCTGGCCCAA
TGGAAGGCGGCGTCCGCGCCACCGGCCGAGGACAACGCGGCCGACCGGCTCACGCTCGCC
ACCGCCGACGAGGTGCTCGCGTTCATCGACAACGAACTCGGCACCTCGTGA
[5] KS35..409
[5] AT597..918
[5] methylmalonyl-CoA791..795
[5] dh966..1134
[5] kr1476..1653
[5] ACP1728..1798
[6] KS1822..2199
[6] AT2360..2677
[6] malonyl-CoA2552..2556
[6] dh2724..2889
[6] er3193..3503
[6] KR3513..3693
[6] ACP3798..3868
[5] KS103..1227
[5] AT1789..2754
[5] methylmalonyl-CoA2371..2385
[5] dh2896..3402
[5] kr4426..4959
[5] ACP5182..5394
[6] KS5464..6597
[6] AT7078..8031
[6] malonyl-CoA7654..7668
[6] dh8170..8667
[6] er9577..10509
[6] KR10537..11079
[6] ACP11392..11604

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR001227 Acyl transferase domain (Domain)
[593-720] G3DSA:3.40.366.10 [791-907] G3DSA:3.40.366.10 [2351-2485] G3DSA:3.40.366.10 [2552-2664] G3DSA:3.40.366.10
G3DSA:3.40.366.10   Ac_transferase_reg
IPR006162 Phosphopantetheine attachment site (PTM)
[1756-1771] PS00012 [3826-3841] PS00012
PS00012   PHOSPHOPANTETHEINE
IPR009081 Acyl carrier protein-like (Domain)
[1731-1797] 2.3e-11 PF00550 [3802-3867] 6.40000000000001e-11 PF00550
PF00550   PP-binding
[1721-1839] 1.50000306971104e-25 SSF47336 [3790-3885] 1.50000306971104e-23 SSF47336
SSF47336   ACP_like
[1728-1798] PS50075 [3798-3868] PS50075
PS50075   ACP_DOMAIN
[1725-1801] 6.40000000000004e-44 G3DSA:1.10.1200.10 [3795-3871] 6.40000000000004e-44 G3DSA:1.10.1200.10
G3DSA:1.10.1200.10   ACP_like
IPR011032 GroES-like (Domain)
[3184-3338] 2.70000183580794e-29 SSF50129
SSF50129   GroES_like
IPR013154 Alcohol dehydrogenase GroES-like (Domain)
[3213-3268] 7.5e-08 PF08240
PF08240   ADH_N
IPR013968 Polyketide synthase, KR (Domain)
[1476-1650] 2.80000000000001e-41 PF08659 [3513-3691] 2.19999999999997e-56 PF08659
PF08659   KR
IPR014030 Beta-ketoacyl synthase, N-terminal (Domain)
[35-283] 5.99999999999995e-91 PF00109 [1822-2073] 1.60000000000002e-91 PF00109
PF00109   ketoacyl-synt
IPR014031 Beta-ketoacyl synthase, C-terminal (Domain)
[291-409] 1.99999999999999e-47 PF02801 [2081-2199] 3.89999999999997e-48 PF02801
PF02801   Ketoacyl-synt_C
IPR014043 Acyl transferase (Domain)
[597-918] 6.60000000000002e-101 PF00698 [2360-2677] 3.49999999999995e-67 PF00698
PF00698   Acyl_transf_1
IPR015083 Polyketide synthase, docking (Domain)
[3-27] 3.90000000000001e-10 PF08990
PF08990   Docking
[2-35] 1.89999859865864e-10 SSF101173
SSF101173   Polyketide_synth_docking
IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase (Domain)
[595-900] 1.90000694315261e-67 SSF52151 [2358-2649] 3.49999466863949e-65 SSF52151
SSF52151   Acyl_Trfase/lysoPlipase
IPR016036 Malonyl-CoA ACP transacylase, ACP-binding (Domain)
[722-790] 7.70000171387738e-16 SSF55048 [2487-2551] 4.80000830876748e-17 SSF55048
SSF55048   Malonyl_transacylase_ACP-bd
IPR016038 Thiolase-like, subgroup (Domain)
[35-294] G3DSA:3.40.47.10 [295-460] G3DSA:3.40.47.10 [1825-2085] G3DSA:3.40.47.10 [2086-2251] G3DSA:3.40.47.10
G3DSA:3.40.47.10   Thiolase-like_subgr
IPR016039 Thiolase-like (Domain)
[27-459] 2.89997807423186e-103 SSF53901 [1815-2197] 2.80000504261099e-103 SSF53901
SSF53901   Thiolase-like
IPR016040 NAD(P)-binding domain (Domain)
[1472-1659] 6.6999999999999e-53 G3DSA:3.40.50.720 [3328-3424] 1.4e-17 G3DSA:3.40.50.720 [3513-3693] 6.6999999999999e-53 G3DSA:3.40.50.720
G3DSA:3.40.50.720   NAD(P)-bd
IPR018201 Beta-ketoacyl synthase, active site (Active_site)
[196-212] PS00606 [1986-2002] PS00606
PS00606   B_KETOACYL_SYNTHASE
IPR020801 Polyketide synthase, acyl transferase domain (Domain)
[599-899] 5.50001754266469e-119 SM00827 [2362-2658] 8.50003024809049e-115 SM00827
SM00827   PKS_AT
IPR020806 Polyketide synthase, phosphopantetheine-binding domain (Domain)
[1729-1801] 9.59999914716171e-32 SM00823 [3799-3871] 2.10000267834031e-32 SM00823
SM00823   PKS_PP
IPR020807 Polyketide synthase, dehydratase domain (Domain)
[966-1134] 3.29999077503323e-64 SM00826 [2724-2889] 1.10000150671643e-59 SM00826
SM00826   PKS_DH
IPR020841 Polyketide synthase, beta-ketoacyl synthase domain (Domain)
[37-462] SM00825 [1825-2251] SM00825
SM00825   PKS_KS
IPR020842 Polyketide synthase/Fatty acid synthase, KR (Domain)
[1476-1653] 9.00000407957274e-21 SM00822 [3513-3693] 5.6999970878395e-49 SM00822
SM00822   PKS_KR
IPR020843 Polyketide synthase, enoylreductase (Domain)
[3193-3503] SM00829
SM00829   PKS_ER
SignalP No significant hit
TMHMM No significant hit
Nanch_00100 Nanch_00100   Nanch_00120 Nanch_00120
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