Phosl_00170 Phosl_00170   Phosl_00190 Phosl_00190

Phosl_00180 : CDS information

close this sectionLocation

Organism
StrainHK803
Entry namePhoslactomycin
Contig
Start / Stop / Direction41,551 / 48,867 / + [in whole cluster]
41,551 / 48,867 / + [in contig]
Location41551..48867 [in whole cluster]
41551..48867 [in contig]
TypeCDS
Length7,317 bp (2,438 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category1.1 PKS
Productpolyketide synthase
Product (GenBank)Plm1
Gene
Gene (GenBank)plm1
EC number
Keyword
Note
Note (GenBank)
  • polyketide synthase type I
Reference
ACC
PmId
[12819191] Enhancement and selective production of phoslactomycin B, a protein phosphatase IIa inhibitor, through identification and engineering of the corresponding biosynthetic gene cluster. (J Biol Chem. , 2003)
[17256943] Modular polyketide synthases and cis double bond formation: establishment of activated cis-3-cyclohexylpropenoic acid as the diketide intermediate in phoslactomycin biosynthesis. (J Am Chem Soc. , 2007)
[23790488] Structural and stereochemical analysis of a modular polyketide synthase ketoreductase domain required for the generation of a cis-alkene. (Chem Biol. , 2013)
comment
[PMID: 12819191](2003)
Phoslactomycins生合成gene clusterのクローニング、配列解析報告。

plm1はPKSのLoading Module(AT-ACP)とModule 1(KS-AT-DH-KR-ACP)をコードする。
Plm1は、たぶんCHC-CoAのloadを担う開始domainと、最初の伸長domainを含む。

CHC = cyclohexanecarboxylic acid

---
[PMID:17256943](2007)
module 1はC14-C15 cis型二重結合の確立を担うことを、合成基質を用いたPLM B産生によって確認している。

---
[PMID:23790488](2013)
Plm1のKR domain(PlmKR1)が、
3-ketocyclohexylpropionyl-SNAC → L-3-hydroxycyclohexylpropionyl-SNAC
への変換を担うA-type KRsであることを、生化学、構造、配列で確認している。

close this sectionPKS/NRPS Module

0
1 malonyl-CoA
AT201..517
ACP567..640
KS661..1034
AT1188..1491
DH1534..1698
KR1998..2177
ACP2283..2353

close this sectionSequence

selected fasta
>polyketide synthase [Plm1]
MVPSARSRVVLLLARTDEEDQPDWDDVPGVSVCAPRDSGSIFATAETCLRADRPALVVVH
DETGGVAVALALETAGAEHYGPLCDDAEERAAQLRALRPRDRTSALDATTAGTVPLLLSG
RTEAGLRAHAGRLATHLQERTDISVADAAFTQATARTLWPHRAMVAVADRDAVVSALRAM
AEGRAGDAAVRAGSGGPQSAVFVFPGQGAQWVGMARELAATTPVFRDKLAECARELRPFV
DFELDDVLSGALPLERVEVIQPALFAVMVSLAELWRSNGVTPAAVVGHSFGEIAAVTAAG
ALTVTDGARLVAAVSKALARLQGNGEMVAVALPAEQVTALVAEWDLDLDIAVVNGPGSTV
VAGTTESATALLERLRARDVRATLLPIGIAGHSWRMEPAHEYLVQEAAAVRPRVTGIPVY
TSTTTDPLDTGGLDAEHWFRSLREPARFQQVIEELLGRGHRVFVEMSPHPVLTLPIEETA
AHLGRDVVVLDTMRRDDAGHDRYLYALAEAHLHGVAPDWSTVLPDARRVSLPPYRLDLDT
ADATGSGGTGPGTGLRERLLGCAPAQRVDEALRLVTDAVAAHIEPMARAIGTDEAFWSLG
VDSAGALRIRNRLVEVTGLRLPVTVLFDHPTPRALAEELVRAVLGGDAPTPAATAPADPD
EPLAIVGMACRFPGGVRSPDELWQLVHEGRDAVAAFPTDRGWDLAALYDADASQPGTSYQ
REAALLDGVAEFDAAFFGISSREARAMDPQQRLLLETSWEALERGGIDSATLRGSRTGVF
TGVMSLPYGRPLHQARPDLEGYVMTGTTSSVVSGRLSYVLGLEGPALTLDTACSSSLVAL
HLAGQSLRRGESDLALVGGATVMAEPGLFIEFSRLRALAPDGRSKPFSADADGFGMAEGV
AVLVVERLSDARRLGHDVLAVVRGSAVNQDGASNGLTAPSGPAQQRVIRAALDSAGLRAA
DIDVVEAHGTGTRLGDPIEAQALIATYGSDRPAERPLYLGSLKSNIGHAQAAAGVAGVVK
MVQALRHGVMPRSLYADHPTTEVEWSSETVELLAEERAWDRADGRPRRAGVSAFGISGTN
AHIILEECAPQTPVTSRGAESGVPWTDVAMPLVLSGKTPDAVREQARALREHLASHPELP
LAHVARELATRRTAFEHRAVVTGDREEVRAGLGDVSPVLAGSGRVAAVFSGQGAQRAGMG
RQLAADFPVFDEALTEVCGHLETMLGRGLREVMWSDDPELLGRTEFAQPALFAFELALAR
LWQSWGVSFTAVVGHSVGEIAAAVVAGVLTVPDAARLVVARGRLMQSLPGGGAMLAVAAG
EDEVAATLGDSALVGIAAVNGPEAVVVSGARDEVARVGKVWRARGRRVAELRVGHAFHSP
LMEPILDEFRSVVEELRFRPPTVPLRATADTTCPVDTAAYWVDHVHNAVRFGDAVGQLAE
ADILIEVGPDAALAPLIETGHTVLASTRRDRSETHTVLTSLGRAHAHGADVDWAALLPPA
PRADLPTYAFQRQRYWDSASDATAGAAGADPQPHPMLTSRTDLPGDGGLLLSGRLAPGSD
PWLSHHVVMGTVLLPGTGFVELALEAARAAGAGSVDELVLRAPMVFAEGKPRDLQVWVGP
GQDAERELQIRTRETGGDWTLHATGLLAARTADTAGFRDGDWTGGVWPPAGARQLVGRSF
YEELAARGYEYGPAFRGTKALWERAGDLFAEVMLPARQPRGFGIHPALLDAALHALPITG
SLYEAGEVRLPFSFNSVSLFSSDARRLRVRIRADADSAAVWIADDTGSPVLAMEGLILRS
IERAQLEAAGATGRTGWFSETWRQLGRAATADRVPGNWLLLGEVPPALGSLFDDPLTAAS
WDRSTAPDGVLVGAGAAEDLLAALHEVAGHPTGPVWCVTSRAVGVGTVDDPAADVRAAGV
WGLGRVAGLELPDRWGGLVDLPERIDDATRRALAGTLTDDGADDQDGEDQLAVRDGQLWA
RRLVTTPAPQTGTWTPKGTVLITGGTGGLGGHVARRVAEQGSADRILLLSRQGSAAPGAT
ELLEGIRAFGATAEAVAVDVTDRAAMSGLIDALAAEGAPVRTVVHAAGVVRDVRIAETGA
EELAAQMAAKVEGALLLDELLPDLDDFVLFSSISGIWGAAGQAGYAAGNACLDALARRRR
EQGKRAVSVAWGPWAGGGMLTEHDERELRKRGLTPLLVPAALQAMEQAIMSDRAGDPVVA
DVTWSRFLPAFTASRPSPLFGSFEEKAAPEHQAPSDGRRTEGETQGLTQRLAALPDAERL
PALTEVVQTHVAALIGESGPERVSPDRALKEIGFDSLMSVELRNRFAGLIGVKLPATLVF
DHPTPNALARHLLGHLDFGAAGAAPADRPLLEVVEDLQNRVLSPLTDAATRQALAGRLTE
LLDRLAALDARPVAEADGLASASAAELMQFIDTELGDI
selected fasta
>polyketide synthase [Plm1]
GTGGTTCCGTCCGCCCGCAGCCGTGTGGTGCTTCTGCTCGCACGGACGGACGAGGAGGAC
CAGCCGGACTGGGACGACGTCCCCGGTGTGAGCGTGTGTGCTCCGCGGGACTCCGGCTCG
ATCTTCGCGACGGCCGAGACGTGTCTGCGCGCGGATCGCCCCGCGCTGGTCGTCGTCCAC
GACGAGACCGGCGGCGTGGCGGTGGCGCTGGCTCTGGAGACGGCCGGTGCCGAGCACTAC
GGCCCGCTCTGCGACGACGCCGAGGAGCGCGCGGCGCAGCTGCGCGCGCTCAGGCCCCGG
GACCGCACGAGCGCCTTGGATGCCACGACTGCCGGCACCGTCCCGCTACTGCTGTCCGGC
CGTACCGAGGCCGGTCTGCGCGCCCATGCCGGCCGTCTGGCGACCCACCTCCAGGAGCGT
ACGGACATCTCCGTGGCCGACGCCGCCTTCACCCAGGCCACGGCACGCACCCTCTGGCCG
CACCGGGCGATGGTCGCCGTGGCCGACCGGGATGCCGTCGTCTCAGCTCTTCGCGCGATG
GCCGAGGGCCGGGCGGGCGACGCGGCGGTTCGGGCCGGGAGCGGTGGACCACAGTCCGCG
GTGTTCGTCTTCCCGGGCCAGGGCGCCCAGTGGGTGGGGATGGCGCGCGAACTCGCCGCG
ACGACCCCGGTCTTCCGCGACAAACTGGCCGAATGTGCACGGGAGTTGCGCCCGTTCGTG
GACTTCGAGCTCGACGACGTGCTCTCCGGGGCCCTCCCGCTGGAGCGGGTCGAGGTGATC
CAGCCGGCCCTGTTCGCCGTCATGGTCTCGCTCGCGGAGCTGTGGCGGTCGAACGGCGTC
ACGCCCGCGGCGGTCGTGGGCCACAGTTTCGGCGAGATCGCGGCGGTGACCGCCGCCGGA
GCGCTCACCGTGACGGACGGCGCGCGGCTGGTCGCCGCCGTCAGCAAGGCGCTGGCGCGG
CTCCAGGGCAACGGGGAGATGGTCGCCGTGGCGCTCCCCGCCGAGCAGGTCACCGCTCTG
GTCGCCGAGTGGGATCTGGACCTGGACATCGCGGTCGTCAACGGCCCCGGCTCCACGGTC
GTCGCGGGCACCACCGAGTCCGCGACGGCCTTGTTGGAGCGGCTGCGCGCCCGGGACGTG
CGGGCCACACTGCTGCCCATCGGGATCGCCGGACACTCGTGGCGCATGGAGCCCGCCCAC
GAGTACCTCGTGCAGGAGGCCGCTGCGGTACGGCCGCGCGTCACCGGGATACCCGTGTAC
ACGTCCACCACGACCGATCCGCTCGACACCGGCGGCCTGGATGCCGAGCACTGGTTCCGC
AGCCTTCGCGAGCCCGCCCGGTTCCAGCAGGTCATCGAGGAACTGCTCGGCCGGGGCCAC
CGGGTGTTCGTGGAGATGAGCCCGCACCCGGTGCTCACCCTGCCGATCGAGGAGACCGCC
GCGCACCTCGGCCGCGACGTCGTCGTCCTCGACACGATGCGTCGTGACGACGCGGGCCAC
GACCGCTACCTGTACGCCCTGGCCGAGGCGCACCTGCACGGCGTCGCCCCCGACTGGAGC
ACCGTCCTGCCCGACGCCCGCCGCGTCTCGCTGCCTCCCTACCGGCTCGACCTGGACACG
GCGGACGCCACCGGCAGCGGCGGCACCGGGCCCGGCACCGGACTGCGTGAGCGACTGCTC
GGGTGCGCCCCGGCGCAACGCGTCGACGAGGCCCTCCGCCTCGTGACGGACGCCGTGGCC
GCGCACATCGAGCCGATGGCGAGGGCCATCGGCACGGACGAGGCGTTCTGGTCGCTGGGG
GTGGACTCCGCGGGCGCCCTGCGGATCCGCAACCGGCTGGTCGAGGTGACCGGGCTGCGG
CTGCCCGTGACGGTCTTGTTCGACCACCCCACTCCGCGCGCGCTGGCGGAGGAACTGGTG
CGCGCGGTGCTCGGCGGCGACGCACCGACCCCGGCCGCGACGGCGCCGGCCGACCCCGAC
GAGCCGCTCGCCATCGTCGGCATGGCCTGCCGGTTCCCCGGCGGGGTCAGGTCCCCGGAC
GAGTTGTGGCAGCTGGTGCACGAAGGGCGGGACGCGGTCGCGGCCTTCCCGACCGACCGC
GGCTGGGACCTCGCCGCGCTGTACGACGCCGACGCCTCGCAGCCGGGCACCTCGTATCAG
CGCGAAGCCGCTCTGCTCGACGGCGTGGCCGAGTTCGACGCCGCCTTCTTCGGCATCTCC
TCGCGTGAGGCGCGGGCGATGGACCCGCAGCAGCGGCTGCTGCTGGAGACGTCGTGGGAA
GCGCTGGAGCGCGGCGGGATCGACAGTGCGACCCTGCGGGGCAGCCGGACCGGTGTATTC
ACCGGCGTCATGAGCCTGCCGTACGGCCGGCCGCTGCACCAGGCACGGCCCGACCTGGAG
GGCTATGTGATGACGGGTACCACCTCCAGCGTGGTCTCCGGCCGGCTGTCCTACGTCCTG
GGCCTGGAAGGTCCCGCCCTCACCCTCGACACGGCCTGCTCCTCCTCCTTGGTGGCGCTG
CACCTGGCGGGTCAGTCGCTGCGCCGCGGCGAGAGCGACCTGGCGCTGGTGGGCGGGGCG
ACGGTGATGGCCGAGCCCGGACTGTTCATCGAGTTCAGCAGGCTCCGCGCGCTCGCGCCC
GACGGCCGTTCCAAACCGTTCTCCGCCGATGCCGACGGCTTCGGCATGGCCGAGGGCGTG
GCCGTGCTGGTGGTGGAGCGGCTGTCCGACGCGCGGCGACTGGGCCATGACGTGCTGGCG
GTGGTCAGGGGGAGCGCCGTCAACCAGGACGGCGCCTCCAACGGCCTCACCGCGCCCAGC
GGCCCCGCCCAGCAGCGGGTGATCCGGGCCGCGCTGGACAGTGCCGGCTTGCGCGCCGCG
GACATCGACGTGGTGGAGGCGCACGGCACCGGGACGCGGCTGGGCGACCCCATCGAGGCA
CAGGCGCTGATCGCGACGTACGGGAGCGATCGCCCCGCCGAACGGCCGTTGTACCTCGGT
TCCTTGAAGTCGAACATCGGGCACGCGCAGGCGGCCGCCGGGGTGGCCGGGGTGGTGAAG
ATGGTGCAGGCGCTGCGGCACGGTGTGATGCCGCGCAGCCTGTACGCGGACCATCCGACG
ACGGAGGTGGAGTGGTCGTCGGAGACGGTCGAGCTGCTGGCCGAGGAGCGCGCGTGGGAT
CGTGCCGACGGTCGCCCGCGCCGAGCCGGTGTGTCCGCCTTCGGGATCAGCGGGACGAAC
GCGCACATCATCCTGGAGGAGTGCGCGCCGCAGACTCCGGTGACCTCCCGGGGCGCGGAG
TCCGGCGTCCCCTGGACGGACGTGGCGATGCCGCTGGTGCTCTCCGGCAAGACTCCGGAC
GCCGTACGCGAGCAGGCGCGGGCGCTGCGGGAGCACCTCGCGTCGCACCCGGAGCTGCCA
CTGGCGCACGTCGCCCGGGAGCTGGCCACGCGCCGTACGGCGTTCGAGCACCGCGCCGTG
GTCACGGGCGACCGGGAGGAGGTCCGGGCCGGTCTCGGCGACGTCTCCCCGGTGCTCGCC
GGGTCCGGCAGGGTGGCGGCCGTGTTCTCCGGCCAGGGCGCGCAGCGCGCGGGGATGGGC
CGGCAACTGGCCGCGGACTTCCCGGTGTTCGACGAGGCGTTGACGGAGGTGTGCGGCCAC
CTCGAGACGATGCTCGGACGTGGACTGCGGGAAGTGATGTGGTCCGACGATCCGGAACTA
CTGGGCCGGACGGAGTTCGCACAGCCCGCGCTGTTCGCGTTCGAGTTGGCGCTGGCCCGG
CTGTGGCAGTCCTGGGGCGTGTCGTTCACGGCTGTCGTGGGTCACTCGGTGGGCGAGATC
GCCGCCGCCGTGGTCGCCGGGGTGCTGACGGTGCCGGACGCGGCGCGGCTGGTGGTGGCC
CGGGGCCGGCTGATGCAGTCCCTGCCCGGCGGGGGCGCCATGCTCGCCGTCGCCGCGGGC
GAGGACGAGGTGGCGGCCACACTGGGCGATTCCGCGCTCGTCGGAATCGCCGCGGTCAAC
GGGCCCGAGGCGGTCGTCGTCTCCGGTGCCCGCGACGAGGTGGCACGCGTGGGCAAGGTC
TGGCGTGCACGCGGCCGGCGTGTCGCCGAGCTCCGGGTGGGCCACGCCTTCCACTCACCG
CTCATGGAGCCGATCCTCGACGAGTTCCGCTCGGTGGTGGAGGAGCTGCGCTTCCGGCCG
CCGACCGTCCCGCTCCGTGCCACCGCCGACACCACCTGCCCCGTCGACACCGCCGCCTAC
TGGGTCGACCACGTGCACAACGCCGTACGGTTCGGCGACGCCGTAGGGCAGCTCGCCGAG
GCCGACATCCTGATCGAGGTCGGCCCGGACGCCGCCCTGGCCCCGCTGATCGAGACCGGT
CACACCGTCCTGGCCAGCACCCGGCGCGACCGGTCCGAGACGCACACCGTCCTCACCTCG
CTGGGCCGGGCCCATGCCCATGGCGCCGACGTCGACTGGGCCGCGCTCCTGCCGCCCGCT
CCCCGTGCCGACCTGCCCACGTACGCCTTCCAGCGGCAGCGCTACTGGGACTCCGCGTCG
GACGCCACCGCCGGTGCCGCGGGAGCGGATCCGCAGCCGCACCCGATGCTCACCTCGCGC
ACGGATCTGCCGGGTGACGGCGGCCTGCTGCTGTCCGGCAGGCTGGCACCCGGCAGCGAC
CCGTGGCTGTCGCATCACGTCGTCATGGGCACGGTGCTGCTGCCCGGCACGGGCTTCGTC
GAGCTCGCGCTCGAAGCGGCCCGCGCGGCCGGCGCCGGGTCGGTCGACGAACTCGTCCTG
CGCGCGCCGATGGTGTTCGCCGAGGGCAAGCCCCGCGACCTCCAGGTGTGGGTGGGGCCG
GGCCAGGACGCCGAGCGTGAACTGCAGATCCGTACCAGGGAGACCGGCGGCGACTGGACG
CTGCACGCCACCGGTCTCCTCGCGGCGCGGACCGCCGACACCGCAGGCTTCCGCGACGGC
GACTGGACCGGCGGGGTCTGGCCCCCGGCCGGTGCGCGGCAGCTCGTCGGCCGCTCGTTC
TACGAGGAGCTCGCGGCCCGTGGCTACGAGTACGGCCCGGCTTTCCGGGGCACCAAGGCC
CTCTGGGAGCGTGCCGGCGACCTCTTCGCGGAGGTCATGCTCCCCGCGCGGCAGCCGCGC
GGGTTCGGTATCCACCCCGCACTACTGGACGCCGCCCTGCATGCCCTGCCGATCACCGGC
AGCCTCTACGAGGCCGGCGAGGTCCGGCTGCCGTTCTCCTTCAACAGCGTGTCCCTGTTC
TCCTCGGATGCCCGGCGGCTGCGTGTGCGGATCCGGGCGGACGCCGACTCCGCCGCCGTG
TGGATCGCGGACGACACCGGGTCCCCCGTCCTCGCCATGGAGGGCCTCATCTTGCGCTCC
ATCGAGCGCGCACAGCTGGAAGCGGCGGGGGCGACCGGCCGCACCGGGTGGTTCTCAGAG
ACGTGGCGGCAACTGGGGCGGGCCGCCACGGCCGACCGGGTGCCCGGCAACTGGCTCCTG
CTCGGCGAGGTGCCCCCGGCGCTCGGCTCCCTCTTCGACGACCCGCTCACCGCCGCTTCC
TGGGACCGCTCGACCGCGCCGGACGGGGTGCTGGTCGGCGCCGGAGCCGCGGAGGATCTG
CTCGCCGCCCTGCACGAGGTCGCCGGGCACCCGACCGGCCCGGTCTGGTGCGTCACGAGC
CGCGCCGTCGGAGTGGGGACGGTCGACGACCCCGCCGCCGACGTGCGGGCGGCGGGTGTC
TGGGGGCTCGGCCGGGTGGCCGGACTGGAACTGCCCGACCGCTGGGGCGGACTGGTGGAT
CTGCCCGAGCGGATCGACGACGCGACGCGGCGGGCGCTGGCCGGGACCCTCACCGACGAC
GGCGCCGACGACCAGGACGGCGAGGACCAACTCGCCGTTCGCGACGGACAGCTGTGGGCT
CGTAGGCTCGTGACCACGCCCGCGCCGCAGACCGGTACCTGGACGCCCAAGGGCACCGTG
CTGATCACCGGCGGGACCGGCGGTCTCGGCGGGCACGTCGCCCGCCGGGTCGCCGAGCAG
GGCAGCGCCGACCGTATTCTCCTCCTCTCCCGTCAGGGTTCGGCGGCCCCCGGCGCCACC
GAACTGCTGGAGGGCATCCGCGCGTTCGGCGCCACGGCGGAGGCCGTCGCCGTTGATGTG
ACGGATCGTGCCGCGATGAGCGGCCTGATCGACGCCCTGGCAGCGGAGGGAGCCCCGGTA
CGCACCGTGGTCCATGCCGCGGGCGTGGTCCGGGACGTGCGGATCGCGGAGACCGGGGCC
GAGGAGCTGGCGGCCCAGATGGCGGCCAAGGTCGAGGGTGCCCTGCTGCTCGACGAACTA
CTGCCGGACCTCGACGACTTCGTCCTGTTCTCCTCCATCTCCGGCATCTGGGGCGCCGCG
GGCCAAGCCGGGTACGCCGCCGGCAACGCCTGCCTCGACGCACTCGCCCGGCGCCGCCGC
GAGCAGGGCAAGCGCGCGGTCTCCGTCGCCTGGGGGCCGTGGGCGGGCGGCGGCATGCTG
ACCGAGCACGACGAACGGGAACTGCGCAAGCGTGGTCTGACCCCTCTCCTGGTGCCCGCC
GCCCTCCAGGCCATGGAGCAGGCCATCATGTCGGACCGCGCGGGGGACCCGGTGGTGGCC
GACGTCACCTGGTCGCGCTTCCTGCCCGCGTTCACCGCCTCCCGGCCCAGTCCGTTGTTC
GGCTCGTTCGAGGAGAAGGCCGCCCCTGAGCACCAGGCACCGTCGGACGGCCGGCGTACC
GAGGGTGAGACGCAGGGCCTCACACAGCGGCTCGCCGCACTGCCGGACGCCGAGCGGCTC
CCCGCCCTGACCGAGGTCGTGCAGACCCATGTGGCGGCACTCATCGGCGAATCCGGACCC
GAGCGGGTCAGTCCCGACCGTGCGCTCAAGGAGATCGGGTTCGACTCCCTGATGTCCGTG
GAACTGCGCAACAGATTCGCCGGTCTCATCGGCGTCAAGCTGCCCGCCACGCTGGTCTTC
GACCATCCGACGCCGAACGCGCTGGCGCGGCATCTTCTGGGGCACCTCGATTTCGGCGCG
GCCGGCGCCGCACCGGCCGACCGGCCGCTGCTGGAGGTGGTCGAGGACCTCCAGAACCGG
GTCCTGTCGCCGCTCACCGATGCCGCCACCCGCCAGGCCCTGGCCGGCCGTCTCACCGAG
CTGCTGGACCGGCTGGCCGCACTCGACGCCAGGCCGGTCGCTGAGGCGGACGGGCTCGCC
TCGGCCAGCGCCGCCGAGCTGATGCAGTTCATCGACACCGAGTTGGGGGACATCTGA
[0] AT201..517
[0] ACP567..640
[1] KS661..1034
[1] AT1188..1491
[1] malonyl-CoA1375..1379
[1] DH1534..1698
[1] KR1998..2177
[1] ACP2283..2353
[0] AT601..1551
[0] ACP1699..1920
[1] KS1981..3102
[1] AT3562..4473
[1] malonyl-CoA4123..4137
[1] DH4600..5094
[1] KR5992..6531
[1] ACP6847..7059

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR001227 Acyl transferase domain (Domain)
[197-321] G3DSA:3.40.366.10 [389-504] G3DSA:3.40.366.10 [1181-1308] G3DSA:3.40.366.10 [1375-1480] G3DSA:3.40.366.10
G3DSA:3.40.366.10   Ac_transferase_reg
IPR006162 Phosphopantetheine attachment site (PTM)
[2311-2326] PS00012
PS00012   PHOSPHOPANTETHEINE
IPR009081 Acyl carrier protein-like (Domain)
[569-641] 1e-33 G3DSA:1.10.1200.10 [2282-2356] 1e-33 G3DSA:1.10.1200.10
G3DSA:1.10.1200.10   ACP_like
[564-677] 3.00000067992871e-26 SSF47336 [2275-2370] 3.69999438558106e-21 SSF47336
SSF47336   ACP_like
[579-639] 2.2e-08 PF00550 [2286-2352] 3.1e-11 PF00550
PF00550   PP-binding
[567-640] PS50075 [2283-2353] PS50075
PS50075   ACP_DOMAIN
IPR013968 Polyketide synthase, KR (Domain)
[1998-2176] 3.60000000000002e-58 PF08659
PF08659   KR
IPR014030 Beta-ketoacyl synthase, N-terminal (Domain)
[661-911] 1.29999999999998e-91 PF00109
PF00109   ketoacyl-synt
IPR014031 Beta-ketoacyl synthase, C-terminal (Domain)
[919-1034] 6.40000000000004e-46 PF02801
PF02801   Ketoacyl-synt_C
IPR014043 Acyl transferase (Domain)
[201-517] 2.20000000000002e-91 PF00698 [1188-1491] 1.09999999999999e-62 PF00698
PF00698   Acyl_transf_1
IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase (Domain)
[199-508] 1.60000240695997e-56 SSF52151 [1184-1474] 1.79999754022375e-62 SSF52151
SSF52151   Acyl_Trfase/lysoPlipase
IPR016036 Malonyl-CoA ACP transacylase, ACP-binding (Domain)
[323-388] 3.00000067992871e-16 SSF55048 [1310-1374] 1.29999924468179e-14 SSF55048
SSF55048   Malonyl_transacylase_ACP-bd
IPR016038 Thiolase-like, subgroup (Domain)
[661-922] 6.40000000000004e-89 G3DSA:3.40.47.10 [923-1089] 5.30000000000001e-61 G3DSA:3.40.47.10
G3DSA:3.40.47.10   Thiolase-like_subgr
IPR016039 Thiolase-like (Domain)
[653-1033] 1.50000965748778e-101 SSF53901
SSF53901   Thiolase-like
IPR016040 NAD(P)-binding domain (Domain)
[1997-2209] 9.60000000000003e-37 G3DSA:3.40.50.720
G3DSA:3.40.50.720   NAD(P)-bd
IPR018201 Beta-ketoacyl synthase, active site (Active_site)
[824-840] PS00606
PS00606   B_KETOACYL_SYNTHASE
IPR020801 Polyketide synthase, acyl transferase domain (Domain)
[203-497] 5.7999965385478e-93 SM00827 [1188-1471] 1.19999063421924e-102 SM00827
SM00827   PKS_AT
IPR020806 Polyketide synthase, phosphopantetheine-binding domain (Domain)
[572-643] 3.0999994589937e-20 SM00823 [2284-2356] 2.30000440726534e-34 SM00823
SM00823   PKS_PP
IPR020807 Polyketide synthase, dehydratase domain (Domain)
[1534-1698] 5.6999970878395e-63 SM00826
SM00826   PKS_DH
IPR020841 Polyketide synthase, beta-ketoacyl synthase domain (Domain)
[663-1088] SM00825
SM00825   PKS_KS
IPR020842 Polyketide synthase/Fatty acid synthase, KR (Domain)
[1998-2177] 5.00000909915354e-47 SM00822
SM00822   PKS_KR
SignalP No significant hit
TMHMM No significant hit
Phosl_00170 Phosl_00170   Phosl_00190 Phosl_00190
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