Rubra_00350 Rubra_00350   Rubra_00370 Rubra_00370

Rubra_00360 : CDS information

close this sectionLocation

Organism
StrainNRRL 3061 (=NBRC 14000)
Entry nameRubradirin
Contig
Start / Stop / Direction58,781 / 59,782 / + [in whole cluster]
58,781 / 59,782 / + [in contig]
Location58781..59782 [in whole cluster]
58781..59782 [in contig]
TypeCDS
Length1,002 bp (333 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category4.1 transcriptional regulator
Productputative LuxR family transcriptional regulator
Product (GenBank)putative transcription regulator
Gene
Gene (GenBank)rubRg2
EC number
Keyword
Note
Note (GenBank)
Reference
ACC
PmId
[18080113] Biosynthesis of rubradirin as an ansamycin antibiotic from Streptomyces achromogenes var. rubradiris NRRL3061. (Arch Microbiol. , 2008)
comment
Rubradirin生合成clusterの報告。

Table1>配列比較からの推定機能
RubRg2(429aa): Transcription regulator

rub cluster内に3つのputative transcription regulator genesあり。
RubRg1 and RubRg2は細菌のtranscription activators（DnrI, RedD, and AfsRを含む)に似ている。
RubRg3はhelix-turn-helix DNA-binding domainを含むresponse regulatorをコードする。

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DnrI, RedD, and AfsRはblast hit上位500件に見られない。
Family/Domain
FD
IPR000792
comment
[IPR000792] Transcription regulator LuxR, C-terminal (Domain)

close this sectionSequence

selected fasta
>putative LuxR family transcriptional regulator [putative transcription regulator]
MDLVRAKIALCDGRIDEAISLCDTGMAVADDPVLASWASIGSMVRAITAMRRGELATMIH
HANQIKEDVIFGREGLWGRDTFPWNSPAWLVVQIIEAEKGWEVAVPLARGLLTSESSARG
LLLSEPSAASFLVRILLRADDRETAERGRRCAAVLAAENPGIHAIATAALHLEALLERDI
SLLQQVAASDCDERTRSSANEDIGDLLSESAGGFRQACMHYETAMRSYADAGSPRDSSRV
RSKLRRSDAPKTAARFWPSSRISVLTDTEYAVAELVASGLTNAEVGGQMYLSRHTVAFHL
RKVFQKVGAKSRIELAVMWKQLTGQDLDVASHG
selected fasta
>putative LuxR family transcriptional regulator [putative transcription regulator]
ATGGACCTGGTCAGGGCCAAGATCGCCCTCTGTGACGGCCGCATCGACGAGGCCATCAGC
CTGTGTGACACGGGAATGGCCGTGGCGGACGACCCGGTTCTCGCGTCGTGGGCCTCGATC
GGGAGCATGGTCCGCGCGATCACCGCGATGCGCCGTGGCGAACTCGCCACGATGATTCAT
CATGCCAATCAGATCAAGGAGGACGTGATTTTCGGCCGGGAGGGGCTGTGGGGCCGGGAC
ACCTTTCCCTGGAACTCCCCCGCCTGGCTCGTCGTCCAGATCATCGAGGCGGAAAAGGGC
TGGGAGGTCGCCGTACCGCTCGCCCGCGGGCTCCTCACGTCCGAGTCGTCGGCCCGGGGC
CTTCTGCTGTCCGAGCCCTCGGCGGCGTCGTTCCTCGTGCGGATTCTGCTGCGGGCCGAC
GACCGGGAGACCGCCGAGCGTGGCCGGCGTTGCGCGGCGGTGCTCGCCGCGGAGAACCCG
GGCATTCACGCCATCGCGACCGCCGCCCTGCACCTTGAGGCGCTGCTTGAGAGGGACATC
AGCCTGCTCCAGCAGGTCGCCGCCTCCGACTGCGACGAGCGGACCCGCTCCTCGGCGAAC
GAGGACATCGGCGATCTCCTGTCCGAGAGCGCGGGAGGGTTCCGGCAGGCGTGCATGCAC
TACGAGACGGCCATGCGCTCGTACGCGGACGCGGGCTCCCCGCGCGACTCGTCCCGGGTC
CGCAGCAAGTTGCGGCGCAGCGACGCGCCCAAGACCGCGGCGAGGTTCTGGCCCAGCAGC
CGGATCTCCGTGCTGACCGACACCGAATACGCGGTGGCTGAGCTGGTGGCGAGTGGACTG
ACGAACGCCGAGGTCGGCGGCCAGATGTACCTGTCGCGTCACACCGTCGCCTTCCACCTC
CGCAAAGTCTTCCAGAAGGTCGGTGCCAAGTCGCGCATCGAACTGGCAGTCATGTGGAAG
CAGTTGACCGGTCAGGATCTGGACGTGGCCAGCCACGGCTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR000792 Transcription regulator LuxR, C-terminal (Domain)
[258-323] PS50043
PS50043   HTH_LUXR_2
[265-279] 9.20000434662057e-08 PR00038 [279-295] 9.20000434662057e-08 PR00038 [295-307] 9.20000434662057e-08 PR00038
PR00038   HTHLUXR
[262-319] 2.2999993566538e-16 SM00421
SM00421   HTH_LUXR
[263-318] 3.3e-13 PF00196
PF00196   GerE
IPR011990 Tetratricopeptide-like helical (Domain)
[3-172] 3.1e-16 G3DSA:1.25.40.10 [205-271] 3.1e-16 G3DSA:1.25.40.10
G3DSA:1.25.40.10   TPR-like_helical
IPR011991 Winged helix-turn-helix transcription repressor DNA-binding (Domain)
[272-321] 4.5e-17 G3DSA:1.10.10.10
G3DSA:1.10.10.10   Wing_hlx_DNA_bd
IPR016032 Signal transduction response regulator, C-terminal effector (Domain)
[243-329] 2.79999889404114e-15 SSF46894
SSF46894   Bipartite_resp_reg_C-effector
SignalP
[1-29] 0.114 Signal
Bacteria, Gram-positive   
[1-29] 0.095 Signal
Bacteria, Gram-negative   
TMHMM No significant hit
Rubra_00350 Rubra_00350   Rubra_00370 Rubra_00370
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