Resis_00110 : CDS information

Location

Organism	Streptomyces resistomycificus
Strain	HKI-237
Entry name	Resistomycin
Contig	AJ585192
Start / Stop / Direction	7,821 / 8,828 / + [in whole cluster] 7,821 / 8,828 / + [in contig]
Location	7821..8828 [in whole cluster] 7821..8828 [in contig]
Type	CDS
Length	1,008 bp (335 aa)

Annotation

Category	5.1 general function
Product	putative phosphotransferase
Product (GenBank)	RemJ protein
Gene
Gene (GenBank)	remJ
EC number
Keyword
Note
Note (GenBank)
Reference	ACC Q70DW7 PmId [14982421] A gene cluster encoding resistomycin biosynthesis in Streptomyces resistomycificus; exploring polyketide cyclization beyond linear and angucyclic patterns. (J Am Chem Soc. , 2004) comment resistomycin生合成gene cluster全体を異種性発現により同定。 RemJ: Kinase 特に詳細な記述はなし。機能推定はAA配列相同性から。
Family/Domain	FD IPR011611, IPR002173 comment [IPR011611] Carbohydrate/purine kinase (Domain) [IPR002173] Carbohydrate/puine kinase, PfkB, conserved site (Conserved_site)

Sequence

>putative phosphotransferase [RemJ protein]
MRIAVTGSIAMDHLMSFPGRFAEQLVADRLHSVSLSFLSDRLEIRRGGVAANIAYGLGRL
GMSPVLVGAAGADFFDYQVWLGQHGVDTDSVLVVPGEHTARFVCTTDADHNQIATFHAGA
MRAAYTIALRDVRARVGELGLVVVSPNDPAAMLRHTEECRGAGLPFVADPSQQLARMDRA
DVRFLLSQARWLFTNEYEAALLQECTGWGAARVLDRVGTWVTTLGAGGVRLERAGHDPLV
VPAVPGVPVADPTGAGDALRAGMLAALALGVPAEPAARLGCALASFALESVGTQTYAPGD
RAVAGRVREVYGERALAELAPVPGLTAVTQKARLS

>putative phosphotransferase [RemJ protein]
GTGCGTATCGCCGTCACCGGGTCCATCGCCATGGACCACCTCATGTCCTTCCCCGGCCGG
TTCGCCGAGCAGCTCGTCGCCGACCGACTGCACAGCGTCTCCCTGTCGTTCCTGTCCGAC
CGGCTGGAGATACGACGTGGCGGCGTCGCCGCCAACATCGCCTACGGCCTCGGTCGGCTC
GGGATGTCCCCGGTGCTGGTCGGCGCGGCGGGGGCGGACTTCTTCGACTACCAGGTCTGG
CTGGGGCAGCACGGCGTCGACACCGACTCCGTTCTGGTCGTGCCGGGCGAGCACACGGCA
CGCTTCGTGTGCACCACCGACGCGGACCACAACCAGATCGCCACGTTCCACGCGGGCGCG
ATGCGGGCGGCGTACACCATCGCCCTGCGGGACGTCCGGGCCCGGGTCGGGGAGCTCGGC
CTGGTGGTCGTGTCGCCCAACGACCCCGCGGCGATGCTGCGGCACACCGAGGAGTGCCGC
GGCGCCGGGCTTCCGTTCGTCGCCGACCCCTCCCAGCAACTCGCCCGCATGGACCGGGCC
GACGTCCGGTTCCTGCTGAGTCAGGCCCGCTGGCTGTTCACCAACGAGTACGAGGCCGCG
CTGCTCCAGGAGTGCACGGGCTGGGGCGCGGCGCGCGTCCTGGACCGGGTTGGCACCTGG
GTGACCACGCTCGGCGCGGGCGGCGTACGCCTCGAGCGCGCCGGCCACGATCCGCTCGTC
GTTCCCGCGGTACCCGGAGTCCCGGTGGCCGATCCGACGGGTGCGGGGGACGCGCTGCGG
GCGGGCATGCTCGCCGCCCTCGCGCTCGGCGTACCGGCCGAGCCGGCGGCCCGCCTCGGC
TGCGCCCTCGCGTCCTTCGCCCTGGAGTCGGTCGGCACCCAGACCTACGCGCCCGGCGAC
CGGGCGGTGGCGGGCCGGGTGCGCGAGGTCTACGGCGAGCGGGCCCTGGCGGAACTGGCA
CCGGTGCCGGGCCTCACGGCCGTGACCCAGAAGGCGAGGCTGTCGTGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR002173 Carbohydrate/puine kinase, PfkB, conserved site (Conserved_site) PS00584 PFKB_KINASES_2 PS00583 PFKB_KINASES_1 IPR011611 PfkB (Domain) PF00294 PfkB
SignalP	Bacteria, Gram-negative Eukaryota
TMHMM	No significant hit

Resis_00100 Resis_00120