Cosmo_00050 : CDS information

Location

Organism	Streptomyces olindensis
Strain	DAUFPE 5622
Entry name	Cosmomycin
Contig	DQ280500
Start / Stop / Direction	3,284 / 4,261 / + [in whole cluster] 3,284 / 4,261 / + [in contig]
Location	3284..4261 [in whole cluster] 3284..4261 [in contig]
Type	CDS
Length	978 bp (325 aa)

Annotation

Category	5.4 hypothetical protein
Product	hypothetical protein
Product (GenBank)	CosY
Gene
Gene (GenBank)	cosY
EC number
Keyword
Note
Note (GenBank)
Reference	ACC Q2PZS1 PmId [16810496] Insights in the glycosylation steps during biosynthesis of the antitumor anthracycline cosmomycin: characterization of two glycosyltransferase genes. (Appl Microbiol Biotechnol. , 2006) comment cosmomycinsを含むanthracycline複合体retamycinの産生株Streptomyces olindensisの染色体14kb領域から、cosmomycin生合成に関連した13genesを同定。 cosY: Unknown CosYについては本文記載なし。

Sequence

>hypothetical protein [CosY]
MPIMLTSEDVDDAFDDEAFMEERFSDVQRLLLGRGPALGPETPVLLPATHCRLTVGPHTS
GPFGRCFAVRLDPGADQSAPRVELLLADDGSLLGLVDAGALDGWRSAIPSGLAARYLAPP
APSLLGLFGSGEPAWSCLLVLHHALPSLSEVHVVGRDPAQARDLATAAALRTGLRVRTSE
DARATAAGADVVATTGGHPRVRAEWLAAGALLIDQTATAATAATAAPTAAGPAVGQVGLV
PPRGPAVRQVSLVPPRGPAEDTRHEPLPLAEIVAGRALPRRSGSDIVHYQGAELAGWSAI
AAAAGLGHAWRRDVGTPVRLGRGSP

>hypothetical protein [CosY]
GTGCCGATCATGCTGACCTCCGAAGACGTGGACGACGCCTTCGACGACGAGGCCTTCATG
GAGGAGCGGTTCTCCGACGTCCAGCGACTGCTCCTAGGCCGTGGGCCGGCGCTCGGCCCC
GAGACCCCGGTCCTGCTCCCCGCCACGCACTGCCGGCTGACCGTGGGACCCCACACCTCC
GGCCCCTTCGGCCGCTGCTTCGCCGTCCGCCTCGACCCCGGCGCCGACCAGTCCGCCCCG
CGCGTGGAACTGCTGCTCGCCGACGACGGATCACTCCTCGGCCTGGTCGACGCCGGCGCC
CTGGACGGCTGGCGCAGCGCCATCCCCTCCGGGCTCGCCGCGCGCTACCTCGCCCCGCCG
GCCCCCTCCCTGCTCGGCCTCTTCGGCTCCGGCGAACCGGCCTGGTCCTGCCTGCTCGTG
CTGCACCACGCGCTGCCCTCGCTCTCCGAGGTGCACGTCGTCGGCCGGGACCCGGCCCAG
GCCCGGGACCTCGCGACGGCCGCCGCCCTGCGCACCGGCCTCAGGGTGCGCACGTCCGAG
GACGCCCGCGCCACCGCAGCGGGCGCCGACGTCGTCGCCACCACCGGCGGTCACCCGCGC
GTCCGCGCCGAATGGCTCGCGGCCGGGGCGCTCCTGATCGACCAGACCGCCACGGCCGCC
ACGGCGGCCACGGCCGCGCCGACCGCCGCCGGCCCCGCCGTCGGGCAGGTCGGCCTCGTG
CCCCCGCGCGGTCCCGCCGTACGGCAGGTCAGCCTCGTCCCTCCGCGCGGCCCCGCCGAG
GACACCCGGCACGAACCCCTGCCCCTCGCCGAGATCGTCGCGGGCCGGGCGCTGCCCCGG
CGCAGCGGCTCCGACATCGTCCACTACCAGGGCGCCGAACTGGCCGGCTGGAGCGCCATC
GCCGCCGCCGCAGGACTCGGCCACGCCTGGCGGCGGGACGTCGGCACCCCCGTGCGGCTG
GGGCGCGGCAGTCCCTGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR003462 Ornithine cyclodeaminase/mu-crystallin (Family) PF02423 OCD_Mu_crystall IPR016040 NAD(P)-binding domain (Domain) G3DSA:3.40.50.720 NAD(P)-bd
SignalP	No significant hit
TMHMM	No significant hit

Cosmo_00040 Cosmo_00060