Indano_00010 : CDS information

Location

Organism	Streptomyces antibioticus
Strain	NRRL 8167
Entry name	Indanomycin
Contig	FJ545274
Start / Stop / Direction	190 / 954 / + [in whole cluster] 190 / 954 / + [in contig]
Location	190..954 [in whole cluster] 190..954 [in contig]
Type	CDS
Length	765 bp (254 aa)

Annotation

Category	5.1 general function
Product	putative hydrolase
Product (GenBank)	metallo beta lactamase family protein
Gene
Gene (GenBank)
EC number
Keyword
Note	It is supposed that this ORF is not involved in indanomycin biosynthesis.
Note (GenBank)	Orf1
Reference	ACC C5HUZ9 PmId [19301315] Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167. (Chembiochem. , 2009) comment indanomycin biosynthetic gene clusterに関する文献。 orf1(254a.a): metallo beta lactamase superfamily protein orf1自体の機能実験は無し。相同性より機能を推定している模様。 indanomycin biosynthesisには関係しないと文中で予想している記載有り。
Family/Domain	FD IPR001279 comment [IPR001279] Beta-lactamase-like (Domain) function; hydrolase activity

Sequence

>putative hydrolase [metallo beta lactamase family protein]
MGELNQVADGVWVRQSEWVWTNSIVVRGEDGLILIDPGIDGSELNLLADDVDRLGIPVVA
GFCTHPHWDHLLWHPRFGDVPRYATPSAAHLAGQARERARAMAAESASGVPLDLVALVTP
LPADGGRMPGEIIEHRAHAVGHAAVLLADRGVLLAGDMLSDVLIPLFDFRQDDQVGAYEA
ALDRLDEAVGHVHVVVPGHGAVAEGPEVAARLAADRAYVDALRRGAEPVDARLGPHADWL
LGPHRSNLEQARGR

>putative hydrolase [metallo beta lactamase family protein]
ATGGGCGAGCTGAATCAGGTGGCCGACGGAGTCTGGGTCCGTCAGAGCGAGTGGGTGTGG
ACCAATTCCATCGTGGTGCGCGGAGAGGACGGGCTGATCCTCATCGATCCCGGCATCGAC
GGCTCCGAGTTGAACCTGCTCGCCGATGACGTGGACCGGCTCGGCATTCCGGTGGTCGCC
GGGTTCTGCACTCATCCCCACTGGGACCACCTGCTCTGGCATCCCCGGTTCGGCGACGTT
CCGCGCTACGCCACCCCCTCCGCCGCCCACCTTGCCGGTCAGGCCCGAGAGCGGGCGCGG
GCGATGGCGGCGGAGAGCGCGTCCGGCGTCCCCCTCGACCTGGTCGCGCTGGTCACCCCG
CTGCCCGCGGACGGCGGACGGATGCCGGGCGAGATCATCGAGCACCGGGCGCACGCTGTC
GGCCACGCCGCGGTCCTCCTCGCGGACCGTGGCGTCCTGCTCGCCGGCGACATGCTCTCC
GACGTCCTGATCCCGCTCTTCGACTTCCGCCAAGACGATCAGGTGGGAGCCTACGAGGCC
GCACTCGACCGGCTGGATGAGGCGGTCGGTCACGTCCATGTAGTGGTCCCCGGCCACGGA
GCCGTTGCCGAAGGCCCCGAGGTGGCGGCGCGTCTCGCCGCCGATCGTGCCTACGTCGAC
GCGCTCCGGCGGGGAGCGGAACCGGTCGACGCGCGTCTGGGACCGCACGCGGACTGGCTC
CTCGGCCCCCACCGGTCGAACCTTGAACAGGCCCGAGGGCGGTAG

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR001279 Beta-lactamase-like (Domain) PF00753 Lactamase_B SM00849 Lactamase_B
SignalP	No significant hit
TMHMM	No significant hit

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