Medem_00040 : CDS information

Location

Organism	Streptomyces sp.
Strain	AM-7161
Entry name	Medermycin
Contig	AB103463
Start / Stop / Direction	3,785 / 2,091 / - [in whole cluster] 3,785 / 2,091 / - [in contig]
Location	complement(2091..3785) [in whole cluster] complement(2091..3785) [in contig]
Type	CDS
Length	1,695 bp (564 aa)

Annotation

Category
Product
Product (GenBank)	nitrite/sulphite reductase
Gene
Gene (GenBank)	ORF X
EC number
Keyword
Note	It is supposed that this ORF is not involved in medermycin biosynthesis.
Note (GenBank)
Reference	ACC Q7WT38 PmId [12855716] Cloning, sequencing and heterologous expression of the medermycin biosynthetic gene cluster of Streptomyces sp. AM-7161: towards comparative analysis of the benzoisochromanequinone gene clusters. (Microbiology. , 2003) comment ORF X: No relation?

Sequence

>[nitrite/sulphite reductase]
MAATPENPTPAAARRKVGRHRGEGQWAVGHFTPLNGNEQFKKDDDGLNVRTRIETVYSKR
GFDSIDPNDLRGRMRWWGLYTQRKQGLDGTKTGVLEPEELDDEYFMLRVRIDGGRLTTEQ
LRVIGEISEEFARGTADITDRQNVQYHWIRIEDVPEIWNRLEAVGLSTTEACGDTPRVIL
GSPVAGIAADEIIDGTPAIEEIYRRIVGNKDFSNLPRKFKSAVSGSPLLDVAHEINDIAF
VGVEHPEHGPGFDVWVGGGLSTNPKLGVRLGTWVSLDEVPDVYEGVISIFRDYGYRRLRN
RARLKFLVADWGPEKFRQVLEDEYLNRKLTDGPAPEQPAGRWRDHVGVHRQKDGRFYVGF
APRVGRVDGATLTKIAGIAEEHGSGRVRTTAEQKMLVLDIEEAQVESIVAALEALDCGSP
PAFRRGTMACTGIEFCKLAIVETKGRGSSLIDELERRIPEFDEPLTININGCPNACARIQ
VADIGLKGQLVLDDDGNRVEGYQVHLGGALGLEAGFGRKVRGLKVTAAELPDYVERVLKR
FQAERETGERFATWTARASEESLS

>[nitrite/sulphite reductase]
ATGGCCGCCACCCCGGAAAACCCCACTCCCGCCGCCGCCCGACGCAAGGTCGGGCGCCAC
CGTGGCGAGGGTCAGTGGGCCGTGGGGCACTTCACCCCCCTGAACGGCAATGAGCAGTTC
AAGAAGGACGACGACGGTCTCAATGTACGGACACGTATTGAGACGGTCTACTCGAAGCGC
GGCTTCGACTCCATCGACCCCAACGACCTGCGCGGACGCATGCGCTGGTGGGGCCTCTAC
ACCCAGCGCAAGCAGGGTCTGGACGGCACCAAGACGGGTGTCCTGGAGCCGGAGGAGCTG
GACGACGAGTACTTCATGCTCCGCGTCCGCATCGACGGCGGCCGGCTGACCACCGAGCAG
CTCCGGGTCATCGGCGAGATCTCCGAGGAGTTCGCCCGCGGCACCGCCGACATCACGGAC
CGGCAGAACGTCCAGTACCACTGGATCCGCATCGAGGACGTCCCCGAGATCTGGAACCGC
CTGGAGGCGGTCGGCCTGTCGACCACCGAGGCCTGCGGCGACACCCCGCGCGTCATCCTC
GGCTCCCCCGTGGCCGGCATCGCCGCCGACGAGATCATCGACGGCACCCCCGCCATCGAG
GAGATCTACCGGCGGATCGTCGGCAACAAGGACTTCTCCAACCTGCCCCGCAAGTTCAAG
TCCGCGGTCTCCGGCTCGCCGCTGCTCGACGTGGCGCACGAGATCAACGACATCGCCTTC
GTCGGCGTGGAGCACCCGGAGCACGGCCCCGGCTTCGACGTGTGGGTCGGCGGCGGTCTG
TCCACCAACCCGAAGCTCGGCGTCCGCCTCGGCACCTGGGTCTCCCTCGACGAGGTCCCC
GACGTCTACGAGGGCGTCATCTCGATCTTCCGCGACTACGGCTACCGCCGGCTGCGCAAC
CGCGCCCGCCTGAAGTTCCTCGTCGCCGACTGGGGCCCGGAGAAGTTCCGCCAGGTCCTG
GAGGACGAGTACCTGAACCGCAAGCTGACGGACGGCCCCGCCCCCGAGCAGCCCGCGGGC
CGCTGGCGCGACCACGTCGGCGTCCACCGCCAGAAGGACGGACGGTTCTACGTCGGTTTC
GCGCCGCGCGTCGGCCGCGTCGACGGCGCCACCCTGACGAAGATCGCCGGGATCGCCGAG
GAGCACGGCTCCGGCCGGGTCCGCACCACCGCCGAGCAGAAGATGCTCGTCCTCGACATC
GAGGAGGCGCAGGTCGAGTCGATCGTCGCCGCCCTGGAGGCGCTGGACTGCGGGTCACCC
CCTGCGTTCCGGCGCGGCACGATGGCCTGCACCGGCATCGAGTTCTGCAAGCTCGCGATC
GTCGAGACGAAGGGCCGCGGCTCCTCGCTCATCGACGAACTGGAGCGGCGCATCCCCGAG
TTCGACGAGCCGCTGACGATCAACATCAACGGCTGCCCGAACGCCTGCGCCCGCATCCAG
GTGGCGGACATCGGTCTCAAGGGCCAGCTGGTCCTGGACGACGACGGCAACCGCGTCGAG
GGCTACCAGGTCCACCTGGGCGGCGCGCTCGGCCTGGAGGCAGGTTTCGGCCGCAAGGTC
CGCGGCCTCAAGGTCACGGCGGCCGAGCTCCCGGACTACGTGGAGCGGGTCCTCAAGCGC
TTCCAGGCGGAGCGCGAGACCGGCGAGCGCTTCGCGACCTGGACGGCCCGCGCGTCGGAG
GAGTCCCTGTCGTGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR005117 Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like (Domain) G3DSA:3.90.480.10 G3DSA:3.90.480.10 PF03460 NIR_SIR_ferr SSF55124 NiR_SiRalpha_1/3 IPR006066 Nitrite/sulphite reductase iron-sulphur/siroheam-binding site (Binding_site) PR00397 SIROHAEM PS00365 NIR_SIR IPR006067 Nitrite/sulphite reductase 4Fe-4S domain (Domain) PF01077 NIR_SIR
SignalP	No significant hit
TMHMM	No significant hit

Medem_00030 Medem_00050