Medem_00050 : CDS information

Location

Organism	Streptomyces sp.
Strain	AM-7161
Entry name	Medermycin
Contig	AB103463
Start / Stop / Direction	4,718 / 4,149 / - [in whole cluster] 4,718 / 4,149 / - [in contig]
Location	complement(4149..4718) [in whole cluster] complement(4149..4718) [in contig]
Type	CDS
Length	570 bp (189 aa)

Annotation

Category
Product
Product (GenBank)	acetyltransferase
Gene
Gene (GenBank)	ORF Y
EC number
Keyword
Note	It is supposed that this ORF is not involved in medermycin biosynthesis.
Note (GenBank)
Reference	ACC Q7WT37 PmId [12855716] Cloning, sequencing and heterologous expression of the medermycin biosynthetic gene cluster of Streptomyces sp. AM-7161: towards comparative analysis of the benzoisochromanequinone gene clusters. (Microbiology. , 2003) comment ORF Y: No relation?

Sequence

>[acetyltransferase]
MRITLTTWSLEQTSPSDLRPSPAPEGDDITIARAAVPSPEYSRFLYTAVGGDIRWNDRLP
LTYKEWEEIVEKPGAEIWVAYDRGTPAGYVELDPQPDGVVEIVYFGLIPAFRGRRIGGHL
LSFGTARAWDLAERWPDREATRRVWLHTCSLDGPHAMANYERRGFRLFDTKVEEVEESET
PGPWPGAHA

>[acetyltransferase]
ATGCGCATCACTCTCACCACCTGGTCCCTCGAACAGACCTCGCCGTCCGATCTCCGCCCC
TCCCCCGCCCCGGAGGGTGACGACATCACGATCGCGCGGGCCGCGGTCCCCTCGCCGGAG
TACAGCCGCTTCCTCTATACGGCGGTCGGCGGCGACATCCGCTGGAACGACCGCCTGCCG
CTCACGTACAAGGAGTGGGAGGAGATCGTCGAGAAGCCGGGGGCCGAGATCTGGGTGGCG
TACGACCGGGGGACGCCGGCCGGGTACGTGGAGCTCGACCCGCAGCCCGACGGCGTCGTC
GAGATCGTCTACTTCGGCCTGATCCCCGCCTTCCGCGGTCGCCGGATCGGCGGCCACCTC
CTCTCCTTCGGAACGGCGCGCGCCTGGGACCTGGCCGAGCGGTGGCCGGACCGGGAGGCC
ACGCGGCGCGTCTGGCTGCACACCTGCTCGCTCGACGGCCCGCACGCGATGGCCAACTAC
GAGCGGCGCGGATTCCGGCTCTTCGACACCAAGGTGGAGGAGGTCGAGGAGTCCGAGACC
CCCGGCCCGTGGCCCGGCGCCCACGCCTGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR000182 GNAT domain (Domain) PF13508 Acetyltransf_7 PS51186 GNAT IPR016181 Acyl-CoA N-acyltransferase (Domain) G3DSA:3.40.630.30 Acyl_CoA_acyltransferase SSF55729 Acyl_CoA_acyltransferase
SignalP	No significant hit
TMHMM	No significant hit

Medem_00040 Medem_00060