Medem_00060 Medem_00060   Medem_00080 Medem_00080

Medem_00070 : CDS information

close this sectionLocation

Organism
StrainAM-7161
Entry nameMedermycin
Contig
Start / Stop / Direction6,358 / 5,738 / - [in whole cluster]
6,358 / 5,738 / - [in contig]
Locationcomplement(5738..6358) [in whole cluster]
complement(5738..6358) [in contig]
TypeCDS
Length621 bp (206 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category5.4 hypothetical protein
Producthypothetical protein
Product (GenBank)putative disulphide-forming protein
Gene
Gene (GenBank)med-ORF26
EC number
Keyword
Note
Note (GenBank)
Reference
ACC
PmId
[12855716] Cloning, sequencing and heterologous expression of the medermycin biosynthetic gene cluster of Streptomyces sp. AM-7161: towards comparative analysis of the benzoisochromanequinone gene clusters. (Microbiology. , 2003)
comment
entire medermycin(med) biosynthetic gene clusterの報告。
Streptomyces coelicolor CH999でmed clusterを発現してmedermycin産生を確認している。

ORF26: Putative disulphide-forming protein

配列解析のみ。gra-ORF19 homolog.
glutaredoxin/thioredoxin superfamilyのredox sensorsに見られるCXXC motifの保存あり。

close this sectionSequence

selected fasta
>hypothetical protein [putative disulphide-forming protein]
MRVEVYFDILCPWCYIGKKRLATALAGRDDVDLVWRSMELDPDGSPTAGPTAAEVIAQYQ
SGPEQAAARVRQIQSLGEAEGVRLDLHKARPVNSFDAHRLVHLGAAHGRADEVLERLLYG
YHTEGLDIAAPEVLEKLGVEAGLDPAAVRRVVEGTEFTEHVRADERRAVEAGVRGVPSLV
VDGGVPASAVQSPEALARLLTPRSRG
selected fasta
>hypothetical protein [putative disulphide-forming protein]
ATGAGGGTCGAGGTGTACTTCGACATCCTGTGCCCCTGGTGCTACATCGGGAAGAAGAGG
CTGGCGACCGCGCTCGCCGGACGCGACGACGTGGACCTCGTCTGGCGCAGCATGGAACTG
GACCCGGACGGCAGTCCGACGGCGGGCCCGACGGCCGCCGAGGTGATCGCCCAGTACCAG
AGCGGTCCCGAGCAGGCCGCCGCCCGGGTGCGGCAGATCCAGTCGCTCGGCGAGGCCGAG
GGGGTGCGGCTCGACCTCCACAAGGCGCGGCCGGTCAACTCCTTCGACGCGCACCGGCTC
GTCCACCTGGGCGCCGCGCACGGGCGGGCCGACGAGGTCCTCGAACGGCTGCTGTACGGC
TATCACACCGAGGGGCTCGACATCGCCGCCCCCGAGGTCCTGGAGAAGCTGGGGGTCGAG
GCGGGTCTCGACCCGGCCGCGGTCCGCCGGGTGGTGGAGGGCACGGAGTTCACGGAGCAT
GTGCGCGCCGACGAACGGCGTGCCGTGGAGGCGGGCGTCAGGGGAGTGCCGTCGCTGGTG
GTCGACGGCGGGGTGCCCGCCTCGGCCGTCCAGAGTCCGGAGGCCCTGGCCCGGCTGCTG
ACCCCCCGGTCGCGTGGCTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR001853 DSBA-like thioredoxin domain (Domain)
[2-200] 6.40000000000004e-42 PF01323
PF01323   DSBA
IPR012336 Thioredoxin-like fold (Domain)
[2-48] 4.3e-13 G3DSA:3.40.30.10 [163-201] 4.3e-13 G3DSA:3.40.30.10
G3DSA:3.40.30.10   Thioredoxin_fold
[1-206] 2.90000354677981e-43 SSF52833
SSF52833   Thiordxn-like_fd
IPR023169 Protein disulphide isomerase, central domain (Domain)
[62-162] 3.2e-17 G3DSA:1.10.472.60
G3DSA:1.10.472.60   G3DSA:1.10.472.60
SignalP No significant hit
TMHMM No significant hit
Medem_00060 Medem_00060   Medem_00080 Medem_00080
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