Ovied_00080 : CDS information

Location

Organism	Streptomyces antibioticus
Strain	ATCC 11891
Entry name	Oviedomycin
Contig	AJ632203
Start / Stop / Direction	6,760 / 7,527 / + [in whole cluster] 6,760 / 7,527 / + [in contig]
Location	6760..7527 [in whole cluster] 6760..7527 [in contig]
Type	CDS
Length	768 bp (255 aa)

Annotation

Category	4.1 transcriptional regulator
Product	putative IclR family transcriptional regulator
Product (GenBank)	IclR-family regulator
Gene
Gene (GenBank)	ovmR
EC number
Keyword
Note
Note (GenBank)
Reference	ACC Q6ZZW5 PmId [15368568] Genetic organization of the biosynthetic gene cluster for the antitumor angucycline oviedomycin in Streptomyces antibioticus ATCC 11891. (Chembiochem. , 2004) comment OvmR: transcriptional regulator oviedomycin生合成gene clusterの報告。 OvmRについては配列解析のみ。 OvmRは、IclR domainを保存。 oviedomycin調節で役割を果たしうる。
Family/Domain	FD IPR005471, IPR014757 comment [IPR005471] Transcription regulator IclR, N-terminal (Domain) [IPR014757] Transcription regulator IclR, C-terminal (Domain)

Sequence

>putative IclR family transcriptional regulator [IclR-family regulator]
MDMHAVSADGRTGERVRAGGTTHAERVFRVQQAFLKLRGRTHGPGELAEAAGLDDSAVHR
ILQSGIYEGVFDRVGRGMYQLGTTAALVGMQAMAHTLDRHTARSILLRLRAATGGGLAFL
YTLAPFGGAQRQCVDMAVGDSDLSELGMTPREVLTVTRSLRVGASGRAILAYLPRPLQER
VAAEPAVTEAGPGVLVDDDALWDSLRDIRDQGYAIGLEECIAGWNSCAAPVMWGRLGSSA
RSSCSCRTPSPSART

>putative IclR family transcriptional regulator [IclR-family regulator]
ATGGACATGCACGCGGTTTCGGCCGACGGACGGACCGGCGAGCGCGTCCGTGCGGGCGGC
ACCACGCACGCGGAGCGCGTGTTCCGGGTCCAGCAGGCGTTCCTCAAGCTGCGCGGCCGG
ACGCACGGCCCCGGAGAGCTGGCCGAGGCGGCCGGACTCGACGACTCCGCCGTCCACCGC
ATCCTGCAATCCGGCATCTACGAGGGCGTCTTCGACCGCGTCGGCCGCGGCATGTACCAA
CTCGGCACCACGGCGGCCCTGGTGGGCATGCAGGCCATGGCGCACACCCTCGACCGCCAC
ACCGCCCGGTCGATCCTGCTCAGGCTGCGCGCCGCCACCGGGGGCGGGCTCGCCTTCCTC
TACACGCTCGCCCCGTTCGGCGGCGCCCAGCGGCAGTGTGTCGACATGGCCGTCGGCGAC
TCCGACCTCTCCGAACTCGGCATGACACCCCGCGAGGTGCTGACCGTCACCCGCTCGCTG
CGCGTCGGCGCGTCCGGCCGCGCCATCCTCGCCTACCTCCCGCGCCCCCTCCAGGAACGG
GTGGCCGCCGAGCCCGCCGTGACCGAGGCGGGCCCCGGCGTGCTGGTGGACGACGACGCG
CTGTGGGACTCACTGCGCGACATACGCGACCAGGGCTACGCCATCGGCCTGGAGGAGTGC
ATCGCCGGCTGGAACTCCTGCGCCGCCCCCGTGATGTGGGGACGGCTGGGGTCTTCGGCG
CGGTCCTCGTGCTCCTGCCGGACTCCGAGCCCGTCCGCCCGGACGTGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR005471 Transcription regulator IclR, N-terminal (Domain) PS51077 HTH_ICLR IPR011991 Winged helix-turn-helix transcription repressor DNA-binding (Domain) G3DSA:1.10.10.10 Wing_hlx_DNA_bd IPR014757 Transcription regulator IclR, C-terminal (Domain) PS51078 ICLR_ED PF01614 IclR
SignalP	No significant hit
TMHMM	No significant hit

Ovied_00070 Ovied_00090