- Oviedomycin, an unusual angucyclinone encoded by genes of the oleandomycin-producer Streptomyces antibioticus ATCC11891.
Mendez C, Kunzel E, Lipata F, Lombo F, Cotham W, Walla M, Bearden DW, Brana AF, Salas JA, Rohr J
[PMID: 12027768]J Nat Prod. 65 (2002) 779-82- Genetic organization of the biosynthetic gene cluster for the antitumor angucycline oviedomycin in Streptomyces antibioticus ATCC 11891.
Lombo F, Brana AF, Salas JA, Mendez C
[PMID: 15368568]Chembiochem. 5 (2004) 1181-7- Elucidation of oxygenation steps during oviedomycin biosynthesis and generation of derivatives with increased antitumor activity.
Lombo F, Abdelfattah MS, Brana AF, Salas JA, Rohr J, Mendez C
[PMID: 18988223]Chembiochem. 10 (2009) 296-303- Engineering precursor metabolite pools for increasing production of antitumor mithramycins in Streptomyces argillaceus.
Zabala D, Brana AF, Florez AB, Salas JA, Mendez C
[PMID: 24148183]Metab Eng. 20 (2013) 187-97
Compound
Oviedomycin
