Sch475_00010 : CDS information

Location

Organism	Streptomyces sp.
Strain	SCC-2136
Entry name	Sch 47554
Contig	AJ628018
Start / Stop / Direction	498 / 1,481 / + [in whole cluster] 498 / 1,481 / + [in contig]
Location	498..1481 [in whole cluster] 498..1481 [in contig]
Type	CDS
Length	984 bp (327 aa)

Annotation

Category	4.3 transport
Product	putative transporter
Product (GenBank)	putative transport system permease ABC transporter
Gene
Gene (GenBank)	schA1
EC number
Keyword
Note
Note (GenBank)
Reference	ACC Q2HR45 PmId [17085966] Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: cloning, sequencing, and characterization. (Mol Cells. , 2006) comment angucyclines Sch 47554 and Sch 47555の生合成に関連したentire gene clusterのクローニング、シークエンス、配列解析からの特徴づけ。 SchA1(327aa): Putative transport system permease ABC transporter 細菌のpermeases familyに属する。
Related Reference	ACC Q93KC0 PmId [11555291] Identification of TogMNAB, an ABC transporter which mediates the uptake of pectic oligomers in Erwinia chrysanthemi 3937. (Mol Microbiol. , 2001) comment Blast 108th, id49%, 3e-75 Erwinia chrysanthemi_togM Inner membrane protein 植物病原菌Erwinia chrysanthemiはペクチンをC源として利用でき、その最初のステップとしてpectic oligomersの取り込み系が働く。complex sugarsの取り込み系であるcarbohydrate uptake transporter-1 familyに属するABCトランスポーター(TogMNAB)がこれを行っているとしている。大腸菌で発現するとoligogalacturonidesの輸送活性があった。Erwinia chrysanthemiではTogBはoligogalacturonidesに対する走化性にも重要らしい。
Family/Domain	FD IPR000515 comment [IPR000515] Binding-protein-dependent transport systems inner membrane component (Family) function; transporter activity

Sequence

>putative transporter [putative transport system permease ABC transporter]
MSMTTAKTDEVVKEQPAPSTPSDQRERDRMRRRLARRRGGGWWPYAFLAPWFIGLFGLTI
YPMLDSLYLSFTNFDLLTPAQWVGTDNYSKMFTDDPVFWDSVHATLLYVVVSVPLKLALA
LGVAMLLNRDLKGIGLYRAAFYLPSLLGGAVAIAIVWRQVFGGDGLFNDFLAWFGIKGQD
WISSPDTALYTLILLAVWQFGTPMVIFLAGLKQLPKDVYEAAAIDGASPVTRFFKITLPL
LTPIVFFNVVLQIIDAFKTFTPAFVISNGSGGPLNSTMLYSLYLYKKGFTDLQMGYASAL
AWVLFLVIAGFTAVNFIASRYWVHYDD

>putative transporter [putative transport system permease ABC transporter]
ATGAGTATGACCACCGCGAAGACAGACGAGGTCGTGAAGGAGCAGCCCGCTCCCTCGACC
CCGTCCGACCAGCGGGAGCGCGACCGTATGCGCCGCCGCCTCGCCAGACGGCGGGGCGGG
GGCTGGTGGCCGTACGCCTTCCTGGCCCCCTGGTTCATCGGCCTGTTCGGCCTGACGATC
TACCCGATGCTGGACTCGCTGTATCTGTCCTTCACCAACTTCGACCTGCTGACTCCGGCG
CAGTGGGTCGGGACCGACAACTACAGCAAGATGTTCACCGACGACCCGGTCTTCTGGGAC
TCGGTGCACGCCACGCTGCTGTACGTCGTCGTCTCGGTGCCGCTGAAGCTCGCGCTCGCG
CTCGGTGTGGCGATGCTGCTCAACCGCGACCTGAAGGGCATCGGTCTGTACCGGGCCGCC
TTCTATCTGCCGTCGCTGCTCGGCGGGGCGGTCGCCATCGCCATCGTGTGGCGGCAGGTC
TTCGGCGGCGACGGCCTGTTCAACGACTTCCTCGCCTGGTTCGGCATCAAGGGCCAGGAC
TGGATCTCCAGCCCCGACACCGCGCTCTACACGCTGATCCTGCTGGCCGTCTGGCAGTTC
GGCACCCCGATGGTCATCTTCCTCGCGGGTCTGAAGCAGCTGCCGAAGGATGTGTACGAG
GCCGCCGCGATCGACGGCGCCTCGCCGGTCACCCGGTTCTTCAAGATCACCCTGCCGCTG
CTGACCCCGATCGTCTTCTTCAACGTGGTCCTGCAGATCATCGACGCGTTCAAGACGTTC
ACCCCCGCCTTCGTCATCAGCAACGGCTCCGGCGGACCGCTCAACTCGACGATGCTGTAC
TCCCTCTACCTGTACAAAAAGGGCTTCACCGACCTCCAGATGGGATACGCCTCGGCTCTC
GCCTGGGTGCTGTTCCTGGTCATCGCTGGCTTCACGGCGGTCAACTTCATCGCCAGCCGC
TACTGGGTCCACTACGACGACTGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR000515 Binding-protein-dependent transport systems inner membrane component (Family) PS50928 ABC_TM1 PF00528 BPD_transp_1
SignalP	Eukaryota
TMHMM	Transmembrane 6

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