Tauto_00040 : CDS information

Location

Organism	Streptomyces spiroverticillatus
Strain
Entry name	Tautomycin
Contig	EF990140
Start / Stop / Direction	3,213 / 2,500 / - [in whole cluster] 3,213 / 2,500 / - [in contig]
Location	complement(2500..3213) [in whole cluster] complement(2500..3213) [in contig]
Type	CDS
Length	714 bp (237 aa)

Annotation

Category	5.1 general function
Product	putative oxidoreductase
Product (GenBank)	putative dehydrogenase
Gene
Gene (GenBank)
EC number
Keyword
Note	This ORF is not involved in tautomycin biosynthesis.
Note (GenBank)	orf(-3)
Reference	ACC C0SMV7 PmId [18708355] Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis. (J Biol Chem. , 2008) comment tautomycin (TTM) biosynthetic gene clusterについての文献。 orf(-3)(237a.a.): dehydrogenase orf(-3)を不活化してもTTMの生産に影響を及ぼさない事が示されている。
Family/Domain	FD IPR002198 comment [IPR002198] Short-chain dehydrogenase/reductase SDR (Domain) Function GO:0016491 oxidoreductase activity

Sequence

>putative oxidoreductase [putative dehydrogenase]
MSSEKKVAIVTGASQGIGAAVADAYRGRGYAVVVTARSIPSSHDPDVLAVPGDLSRPGTG
AQIVEQALDRFGRIDTLVNNAGVYREKPFTDYTDADYDLVTGVNLRGFFDVTRSAIPAML
AGGDGGHVLCVSTSLVDRANARIPAALASLTKGGLVAATKELAIEYAARRIRANAVSLGV
IRTPMHPDDPGGTLAALHPLGRMGEIDDVVEAIMYLEQASFVTGEILHVDGGQSAGF

>putative oxidoreductase [putative dehydrogenase]
ATGAGCTCGGAGAAGAAGGTGGCAATCGTCACCGGTGCTTCACAAGGCATCGGCGCGGCC
GTCGCCGACGCGTACCGCGGGCGCGGGTACGCCGTCGTCGTGACTGCCCGGTCCATCCCC
TCGTCGCACGATCCGGACGTACTCGCCGTGCCCGGCGACCTGAGCCGGCCCGGCACCGGT
GCGCAGATCGTCGAGCAGGCGCTGGACCGCTTCGGCCGGATCGACACTCTGGTGAACAAC
GCCGGCGTCTACCGGGAGAAACCATTCACCGACTACACCGACGCCGACTACGACCTGGTG
ACCGGCGTCAACCTGCGCGGCTTCTTCGACGTCACGCGCAGCGCCATCCCCGCGATGCTC
GCGGGCGGCGACGGCGGGCACGTCCTGTGCGTGTCGACGTCGCTGGTCGACCGCGCCAAC
GCGCGCATACCCGCGGCGCTCGCCTCGCTGACCAAAGGCGGCCTGGTCGCGGCGACGAAG
GAGCTGGCCATCGAATACGCGGCGCGCCGCATCCGCGCCAACGCCGTCTCACTCGGCGTC
ATCCGCACTCCGATGCACCCGGACGACCCGGGCGGCACGCTCGCCGCGCTGCACCCGCTC
GGGCGGATGGGTGAGATCGACGACGTCGTCGAGGCGATCATGTACCTCGAACAGGCCTCG
TTCGTCACCGGCGAGATCCTGCACGTCGACGGCGGCCAGAGCGCCGGCTTCTGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR002198 Short-chain dehydrogenase/reductase SDR (Family) PR00080 SDRFAMILY IPR002347 Glucose/ribitol dehydrogenase (Family) PR00081 GDHRDH IPR016040 NAD(P)-binding domain (Domain) G3DSA:3.40.50.720 NAD(P)-bd
SignalP	Bacteria, Gram-negative Eukaryota
TMHMM	No significant hit

Tauto_00030 Tauto_00050