Tauto_00070 : CDS information

Location

Organism	Streptomyces spiroverticillatus
Strain
Entry name	Tautomycin
Contig	EF990140
Start / Stop / Direction	7,322 / 8,611 / + [in whole cluster] 7,322 / 8,611 / + [in contig]
Location	7322..8611 [in whole cluster] 7322..8611 [in contig]
Type	CDS
Length	1,290 bp (429 aa)

Annotation

Category	4.1 transcriptional regulator
Product	putative LuxR family transcriptional regulator
Product (GenBank)	putative regulatory protein
Gene
Gene (GenBank)	ttmF
EC number
Keyword
Note
Note (GenBank)
Reference	ACC C0SMW0 PmId [18708355] Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis. (J Biol Chem. , 2008) comment tautomycin (TTM) biosynthetic gene clusterについての文献。 ttmF(429a.a.): transcriptional activator ttmFについての機能を調べた実験は行われていない。 TtmFのN末にはresponse regulatorに典型的なautoinducer domainが存在しないとの記載がある。
Family/Domain	FD IPR000792 comment [IPR000792] Transcription regulator LuxR, C-terminal (Domain) Function GO:0003700 sequence-specific DNA binding transcription factor activity GO:0043565 sequence-specific DNA binding

Sequence

>putative LuxR family transcriptional regulator [putative regulatory protein]
MRDSRSQLHTQLPHTPSEGPTATAADDQRDDPLARSLSAWLAGEVHRAIELATTPGGDEN
DPRHAKIWHARLLTRVRELPEATRVLDELTTSYDVADDGGVSAALTTCRAEFALASGDAG
SAFAEANVGLGLAEGAGAYALLPDLHVVLALSAVRQSATSTGLRFARNLGDDALLGRTAH
MRGQCVWAAAQAFEADGGPACVSHLVERLISDDQLTQELLASQPAAAAWLVRLARSMGDE
RLAFKCVVRAESFILKSWGFRSPYAAALHAKGLFEKNPDKLRAACELYPDGWASASAAED
LAQTWSSLRLGRDRAAEQLKRAAAGYERAGAARDLARVASKLRELGVRSGRVRRPMRCDG
HRTGSLTDTEFAVADLVSQGLTNVQVGRQLYISAHTVAFHLKKIFRKMEVSSRVELARTW
VNSDQQTVG

>putative LuxR family transcriptional regulator [putative regulatory protein]
ATGCGTGATAGCCGGTCCCAGCTGCACACCCAGCTGCCCCACACACCGTCTGAAGGTCCT
ACCGCCACCGCGGCCGACGACCAGCGAGACGACCCGCTCGCACGCTCCTTGTCCGCCTGG
CTCGCCGGTGAGGTCCACCGGGCCATCGAGCTGGCCACCACACCCGGCGGCGACGAGAAC
GACCCGAGGCACGCCAAGATCTGGCACGCCCGGCTCCTGACCCGCGTCCGCGAACTTCCG
GAAGCCACGCGGGTGCTCGACGAGTTGACCACCTCGTACGACGTCGCCGACGACGGGGGT
GTTTCAGCCGCGTTGACCACCTGCCGCGCCGAGTTCGCGCTCGCGTCGGGTGACGCCGGC
AGCGCGTTCGCCGAGGCGAACGTCGGCCTCGGGCTGGCCGAAGGGGCCGGCGCCTACGCC
TTGCTGCCGGACCTGCACGTCGTCCTGGCGCTGAGCGCCGTCCGGCAGTCCGCCACGTCG
ACCGGCCTGCGATTCGCGCGCAACCTGGGCGATGACGCTCTGCTCGGCCGCACTGCGCAC
ATGCGCGGGCAGTGCGTGTGGGCCGCCGCTCAGGCGTTCGAGGCCGACGGCGGTCCGGCC
TGCGTCAGTCACCTCGTCGAGCGCCTGATCTCCGACGACCAGCTGACGCAGGAACTCCTC
GCGTCCCAGCCCGCCGCCGCGGCGTGGCTCGTCCGCCTCGCGCGAAGCATGGGAGACGAG
CGACTCGCCTTCAAGTGTGTGGTGCGAGCCGAGTCGTTCATCCTGAAGTCGTGGGGTTTT
CGTTCGCCCTACGCGGCGGCACTGCACGCCAAAGGGCTGTTCGAAAAGAATCCTGACAAA
CTGCGCGCCGCTTGCGAACTGTATCCGGACGGCTGGGCGTCGGCGTCAGCCGCCGAAGAC
CTGGCCCAGACGTGGTCCTCGCTGCGCCTGGGCCGGGATCGCGCCGCCGAACAGTTGAAA
CGCGCAGCCGCCGGTTATGAGCGGGCCGGTGCGGCCCGCGACCTCGCCCGGGTCGCGAGC
AAGCTTCGTGAGCTCGGCGTGCGATCGGGCCGCGTGCGGCGGCCGATGCGCTGCGACGGA
CACCGCACCGGCTCCCTCACGGACACCGAGTTCGCGGTGGCCGACCTGGTGAGCCAGGGC
CTGACGAACGTACAGGTCGGCCGCCAGCTCTACATCTCCGCGCACACCGTGGCGTTCCAT
CTGAAGAAGATCTTCCGCAAGATGGAGGTCTCTTCGCGGGTGGAACTGGCCCGCACGTGG
GTTAACTCGGATCAGCAAACCGTCGGCTGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR000792 Transcription regulator LuxR, C-terminal (Domain) PS50043 HTH_LUXR_2 PR00038 HTHLUXR PF00196 GerE SM00421 HTH_LUXR IPR011990 Tetratricopeptide-like helical (Domain) G3DSA:1.25.40.10 TPR-like_helical IPR011991 Winged helix-turn-helix transcription repressor DNA-binding (Domain) G3DSA:1.10.10.10 Wing_hlx_DNA_bd IPR016032 Signal transduction response regulator, C-terminal effector (Domain) SSF46894 Bipartite_resp_reg_C-effector
SignalP	Bacteria, Gram-negative Bacteria, Gram-positive
TMHMM	No significant hit

Tauto_00060 Tauto_00080