Tetrn_00010 Tetrn_00010   Tetrn_00030 Tetrn_00030

Tetrn_00020 : CDS information

close this sectionLocation

Organism
StrainNRRL 11266
Entry nameTetronomycin
Contig
Start / Stop / Direction1,056 / 1,523 / + [in whole cluster]
1,056 / 1,523 / + [in contig]
Location1056..1523 [in whole cluster]
1056..1523 [in contig]
TypeCDS
Length468 bp (155 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category5.2 function unknown
Productpyridoxamine 5'-phosphate oxidase-like FMN-binding domain protein
Product (GenBank)hypothetical protein
Gene
Gene (GenBank)tmn4
EC number
Keyword
Note
  • It is supposed that this ORF is not involved in tetronomycin biosynthesis.
Note (GenBank)
  • Predicted flavin-nucleotide-binding site is conserved.
Reference
ACC
PmId
[18404760] Analysis of the tetronomycin gene cluster: insights into the biosynthesis of a polyether tetronate antibiotic. (Chembiochem. , 2008)
comment
Streptomyces sp. NRRL 11266におけるtetronomycin (TMN) gene clusterに関する文献。

tmn4(155 aa): pyridoxamine 5'-phosphate oxidase related, FMN-binding protein

tmn4についてはTable 1.以外で特に触れられていないが、本ORFより左側の領域はTMN生合成には関与しないと考えられているとの記載がある。
Family/Domain
FD
IPR011576
comment
[IPR011576] Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain (Domain)
function; pyridoxamine-phosphate oxidase activity, FMN binding

close this sectionSequence

selected fasta
>pyridoxamine 5'-phosphate oxidase-like FMN-binding domain protein [hypothetical protein]
MTAPTHPAEPRTRARRRRDTEHRLAHDVDVWVASAAPDGTPYLVPLSFSWDGAAVWVATP
AGSPTGRNLAATGAARLALGPTRDVTLIDGGVEVFELDALPQEHGDRFAARAGFDPRGAA
GPYRWFRITPRRILAWREVNELKGRELMRDGRWLD
selected fasta
>pyridoxamine 5'-phosphate oxidase-like FMN-binding domain protein [hypothetical protein]
ATGACCGCACCCACGCACCCCGCCGAGCCCCGGACCCGCGCGCGGCGCCGCCGGGACACC
GAGCACCGGCTCGCCCACGACGTGGACGTCTGGGTGGCCAGCGCGGCGCCGGACGGGACG
CCGTACCTCGTGCCGCTGTCGTTCTCCTGGGACGGCGCCGCGGTGTGGGTCGCGACGCCG
GCGGGGAGCCCGACCGGCCGGAACCTCGCCGCCACCGGTGCCGCGCGGCTGGCGCTCGGG
CCCACCCGGGACGTCACGTTGATCGACGGCGGGGTCGAGGTCTTCGAGCTGGACGCGCTG
CCGCAGGAGCACGGCGACCGCTTCGCGGCCCGCGCCGGCTTCGACCCGCGCGGCGCCGCC
GGCCCGTACCGCTGGTTCCGGATCACCCCGCGGCGGATCCTGGCCTGGCGCGAGGTGAAC
GAGCTGAAGGGGCGCGAGCTGATGCGCGACGGCCGCTGGCTGGACTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR009002 FMN-binding split barrel-related (Domain)
[17-141] 1.20000117458134e-14 SSF50475
SSF50475   FMN_binding
IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain (Domain)
[30-83] 5.60000000000001e-07 PF01243
PF01243   Pyridox_oxidase
IPR012349 FMN-binding split barrel (Domain)
[12-152] 1.09999999999999e-43 G3DSA:2.30.110.10
G3DSA:2.30.110.10   PNPOx_FMN_bd
SignalP No significant hit
TMHMM No significant hit
Tetrn_00010 Tetrn_00010   Tetrn_00030 Tetrn_00030
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