Tetrn_00300 Tetrn_00300   Tetrn_00320 Tetrn_00320

Tetrn_00310 : CDS information

close this sectionLocation

Organism
StrainNRRL 11266
Entry nameTetronomycin
Contig
Start / Stop / Direction108,964 / 110,211 / + [in whole cluster]
108,964 / 110,211 / + [in contig]
Location108964..110211 [in whole cluster]
108964..110211 [in contig]
TypeCDS
Length1,248 bp (415 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category5.4 hypothetical protein
Producthypothetical protein
Product (GenBank)hypothetical protein
Gene
Gene (GenBank)tmn24
EC number
Keyword
Note
  • It is supposed that this ORF is not involved in tetronomycin biosynthesis.
Note (GenBank)
  • 25% identity with protein_id: CAB92560.1 - putative carboxylase from Streptomyces coelicolor A3(2)
Reference
ACC
PmId
[18404760] Analysis of the tetronomycin gene cluster: insights into the biosynthesis of a polyether tetronate antibiotic. (Chembiochem. , 2008)
comment
Streptomyces sp. NRRL 11266におけるtetronomycin (TMN) gene clusterに関する文献。

tmn24(415 aa): putative ATP-dependent carboxylate-amine ligase domain protein

tmn24についてはTable 1.以外の文献中で特に触れられていないが、TMN産生に関与するTMN gene clusterの外側に位置しているtmnDI 破壊株でTMN産生に影響が見られないことより、tmnDI のさらに外側に位置している本ORFはTMN産生に関与しないと考えられている。

close this sectionSequence

selected fasta
>hypothetical protein [hypothetical protein]
MGVLYDAGSACAAEVAAAARCCDAELFLVVDRASEHVRARLPVLTRRFALCDITGLAARD
AARAVSEFVPDGLLTFSEHRMEMTSAIAAAIGIPYWHSPAVAGRLVDKLQQRRAFAEAGL
DDLPFAPVADAADLDAALDAVGLPAVLKPRRGAGGRLVQRLDTVSGARAAVAACADAAPG
TDLLVEALLPGDPEAAGAQWGDYVSVETAVHRRECQPLCVTGKFPLAAPFRERGSFVPHT
LDAPLAERAETLAEAAIGALDISDGIVHTQLKLTAEGPRLVEVNGRLGSLVGDVVRRGSG
FDMVAAAMRLALGLPVPDAPRFDEVTYQYSLLPPVHGAAHAPAAGPPDLSARLDGLRHLP
GVDLAVLLDAPAPPGLQDLAAARLGRLQGRTADHAELTRLATAIDELCSPVLGTV
selected fasta
>hypothetical protein [hypothetical protein]
GTGGGCGTCCTGTACGACGCGGGCTCGGCCTGCGCCGCGGAGGTCGCGGCGGCGGCACGC
TGCTGCGACGCCGAGCTGTTCCTCGTCGTGGACCGGGCCTCGGAACACGTGCGGGCGCGG
CTGCCGGTGCTGACGCGGCGGTTCGCGCTGTGCGACATCACCGGTCTCGCCGCGCGGGAC
GCGGCGCGGGCGGTCTCCGAGTTCGTACCCGACGGGCTGCTGACGTTCAGCGAGCACCGG
ATGGAGATGACCTCCGCGATCGCCGCGGCGATCGGCATCCCGTACTGGCACTCCCCCGCG
GTCGCCGGGCGGCTGGTGGACAAGCTCCAGCAGCGCCGGGCGTTCGCCGAAGCGGGCCTG
GACGACCTGCCGTTCGCACCGGTGGCCGACGCCGCGGACCTCGACGCCGCGCTGGACGCG
GTGGGGCTGCCCGCGGTGCTGAAGCCGCGGCGCGGCGCCGGCGGCCGGCTCGTACAGCGC
CTCGACACGGTCTCCGGCGCCCGGGCGGCGGTCGCGGCGTGCGCGGACGCGGCGCCCGGC
ACGGACCTGCTGGTCGAGGCGCTGCTCCCGGGCGACCCCGAGGCGGCCGGGGCGCAGTGG
GGCGACTACGTCTCCGTGGAGACCGCCGTGCACCGCAGGGAGTGCCAACCGCTGTGCGTA
ACGGGGAAGTTCCCCCTTGCCGCGCCCTTCCGGGAGCGCGGCTCCTTCGTCCCGCACACC
CTCGACGCCCCGCTGGCGGAGCGCGCCGAGACCCTGGCGGAGGCGGCGATAGGCGCGCTG
GACATCAGCGACGGCATCGTGCACACGCAGCTGAAGCTCACCGCGGAGGGGCCGCGGCTG
GTCGAGGTCAACGGCCGCCTCGGCAGCCTCGTCGGCGACGTCGTACGGCGCGGGTCGGGC
TTCGACATGGTGGCGGCGGCGATGCGGCTGGCGCTGGGGCTGCCGGTGCCGGACGCACCG
CGGTTCGACGAGGTCACGTACCAGTACTCGCTGCTGCCGCCGGTGCACGGTGCCGCGCAC
GCGCCCGCGGCCGGCCCGCCGGACCTGTCCGCCCGGCTCGACGGGCTGCGCCACCTCCCC
GGCGTCGACCTCGCCGTCCTGCTCGACGCACCGGCACCGCCCGGCCTCCAGGACCTGGCG
GCCGCGCGCCTCGGGCGGCTCCAGGGACGTACGGCGGACCACGCGGAACTCACCCGGCTG
GCAACGGCGATCGACGAACTGTGCAGCCCGGTGCTCGGCACGGTCTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR011761 ATP-grasp fold (Domain)
[112-312] PS50975
PS50975   ATP_GRASP
IPR013815 ATP-grasp fold, subdomain 1 (Domain)
[117-191] 3.3e-10 G3DSA:3.30.1490.20
G3DSA:3.30.1490.20   ATP_grasp_subdomain_1
IPR013816 ATP-grasp fold, subdomain 2 (Domain)
[235-337] 1e-07 G3DSA:3.30.470.20
G3DSA:3.30.470.20   ATP_grasp_subdomain_2
SignalP
[1-39] 0.11 Signal
Eukaryota   
[1-51] 0.039 Signal
Bacteria, Gram-negative   
TMHMM No significant hit
Tetrn_00300 Tetrn_00300   Tetrn_00320 Tetrn_00320
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