Rever_00200 : CDS information

Location

Organism	Streptomyces sp.
Strain	SN-593
Entry name	Reveromycin
Contig	AB568601
Start / Stop / Direction	48,311 / 49,384 / + [in whole cluster] 48,311 / 49,384 / + [in contig]
Location	48311..49384 [in whole cluster] 48311..49384 [in contig]
Type	CDS
Length	1,074 bp (357 aa)

Annotation

Category	5.2 function unknown
Product	AMP-binding family protein
Product (GenBank)	hypothetical protein
Gene
Gene (GenBank)	revL
EC number
Keyword
Note
Note (GenBank)
Reference	ACC G1UDV0 PmId [21642985] Reveromycin A biosynthesis uses RevG and RevJ for stereospecific spiroacetal formation. (Nat Chem Biol. , 2011) comment 配列解析によりrevLのfunctionをUnknownとしている。また、revE〜revNでPost-PKS modificationとしている。実験情報は無し。
Family/Domain	FD IPR000873 comment [IPR000873] AMP-dependent synthetase/ligase (Domain) Pfam> Family: AMP-binding (PF00501)

Sequence

>AMP-binding family protein [hypothetical protein]
MNESLALVDQFLQTDLDEWTRQVVRRHFDPGTGSPYWLKRAAELDFDPLEITRYDELSAL
GPFPLSVLRKLDPADLVPQAVPRPIAGRVFDSGGTTGDPKRILYTPAMLQHRQAWRHWSF
HTEGFRPDGNWVQGTPTGPHVIGLGVQELSSYGGRMYIVDIDPRWVKRLIRAGKLAEADE
YTDHVLGQITNILASQPIDYLNTTSALLTALIRRAPELAAKLKGVRVSGTHCTPAMFRTF
KETLNGGSGAIVGRSYGNTFGTSAGIPDEDDGEILPYLPNYPNVTARVVDKQDWTREVGF
GEQGQVMLNVLHPDLLLPNFLERDQAVRYDTGAAYPCDGVANVMPLQITRNAPEGIY

>AMP-binding family protein [hypothetical protein]
ATGAACGAATCACTGGCTCTGGTCGACCAGTTCCTGCAGACCGACCTCGACGAGTGGACC
CGGCAGGTGGTCCGACGGCACTTCGACCCCGGAACCGGCAGCCCCTACTGGCTCAAGCGC
GCGGCGGAGCTGGACTTCGACCCGCTGGAGATCACCCGCTACGACGAGCTGAGCGCGCTC
GGGCCGTTCCCGCTGTCCGTGCTGCGCAAGCTCGACCCCGCCGACCTGGTTCCCCAGGCG
GTGCCGCGGCCGATCGCCGGCCGGGTCTTCGACTCCGGCGGCACCACCGGCGACCCCAAG
CGCATCCTGTACACGCCCGCCATGCTCCAGCACCGGCAGGCGTGGCGGCACTGGTCGTTC
CACACCGAGGGCTTCCGCCCCGACGGCAACTGGGTGCAGGGCACCCCCACCGGACCGCAC
GTGATCGGCCTCGGCGTCCAGGAACTGTCGTCCTACGGCGGGCGGATGTACATCGTCGAC
ATCGACCCGCGGTGGGTCAAGCGGCTCATCCGCGCCGGCAAGCTCGCCGAGGCCGACGAG
TACACCGACCACGTCCTCGGCCAGATCACCAACATCCTTGCCAGCCAGCCGATCGACTAC
CTCAACACCACGTCGGCCCTGCTCACCGCCCTCATCCGGCGCGCCCCGGAGCTGGCCGCG
AAGCTCAAGGGCGTACGGGTCAGCGGCACCCACTGCACCCCGGCCATGTTCCGCACGTTC
AAGGAGACCCTCAACGGCGGCAGCGGCGCCATCGTGGGGCGCAGCTACGGCAACACCTTC
GGCACCTCGGCCGGCATCCCGGACGAGGACGACGGCGAGATCCTGCCGTACCTGCCGAAC
TACCCCAACGTCACCGCCCGCGTGGTCGACAAGCAGGACTGGACCCGCGAGGTCGGGTTC
GGCGAGCAGGGCCAGGTCATGCTGAACGTCCTGCACCCCGACCTGCTCCTGCCCAACTTC
CTCGAACGGGACCAGGCCGTCCGGTACGACACCGGCGCCGCCTACCCCTGCGACGGCGTC
GCCAACGTCATGCCCCTCCAGATCACCAGGAACGCCCCGGAGGGCATCTACTGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR000873 AMP-dependent synthetase/ligase (Domain) PF00501 AMP-binding
SignalP	No significant hit
TMHMM	No significant hit

Rever_00190 Rever_00210