Gelda2_00090 Gelda2_00090   Gelda2_00110 Gelda2_00110

Gelda2_00100 : CDS information

close this sectionLocation

Organism
StrainNRRL 3602 (=NBRC 14620)
Entry nameGeldanamycin
Contig
Start / Stop / Direction49,428 / 61,118 / + [in whole cluster]
38,128 / 49,818 / + [in contig]
Location49428..61118 [in whole cluster]
38128..49818 [in contig]
TypeCDS
Length11,691 bp (3,896 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category1.1 PKS
Productpolyketide synthase
Product (GenBank)GdmAIII
GenegdmAIII
gdmA3
Gene (GenBank)gdmAIII
EC number
Keyword
Note
Note (GenBank)
  • polyketide synthase; modules 6-7
Reference
ACC
PmId
[12586396] Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602. (FEMS Microbiol Lett. , 2003)
[16085885] Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption. (Appl Environ Microbiol. , 2005)
comment
[PMID:12586396](2003)
ansamycin系抗生物質geldanamycin産生のgene clusterのクローニング、及び配列解析と遺伝子破壊による特性解析についての報告。

GdmA3 (3896aa) : PKS modules 6-7
Module 6 (KS-AT-DH-ER-KR-ACP)
Module 7 (KS-AT-DH-KR-ACP)

GdmA3に関する機能実験無し。

---
[PMID:16085885](2005)
herbimycin生合成系gene clusterのクローニングを行い、同じbenzoquinone ansamycin系のgeldanamycin のgene clusterと比較し、一部の遺伝子欠損株を作成してその生合成における関与を調べた文献。

GdmAIII : PKS modules 6 and 7
Module 6 (KS-AT-DH-ER-KR-ACP)
Module 7 (KS-AT-DH-KR-ACP)

GdmAIII に関する機能実験無し。
Related Reference
ACC
Q06BM4
NITE
Gelda_00010
PmId
[18214443] The LuxR family members GdmRI and GdmRII are positive regulators of geldanamycin biosynthesis in Streptomyces hygroscopicus 17997. (Arch Microbiol. , 2008)
comment
Streptomyces hygroscopicus 17997 でのgeldanamycin生合成clusterにある対応遺伝子(fragment)。

close this sectionPKS/NRPS Module

6 malonyl-CoA
7 methylmalonyl-CoA
KS35..410
AT584..907
DH954..1118
ER1430..1730
KR1740..1920
ACP2022..2092
KS2119..2494
AT2662..2981
DH3029..3197
KR3510..3690
ACP3797..3867

close this sectionSequence

selected fasta
>polyketide synthase [GdmAIII]
MAASREDLVKALRTSLMDAERLKRENDRLIAESTEPVAIVAMACRLPGGVTDPESLWELV
DEGRDAIGPFPTDRGWDLETLFDSDPDAVGKSYVREAGFLEGAGGFDAAFFGISPREALS
LDPQQRLLLETAWETFERAGMDPRSVEGRDIAVFAGGSGQGYGGGPGEAPKGLEGYLGVG
ASGSVISGRVSYTLGLTGPAVTVDTACSSSLVAAHLAVQALRSGECSMALAGGVAVMGQP
TAFVEFSRQRGLAPDGRCKSFGAGADGTTWSEGVGLVLLERLSDARRNGHEVLAVIRGTA
VNQDGASNGLTAPNGPSQERVIRQALSNAGLTVADVDAVEAHGTGTALGDPIEAQAVLAT
YGQSRPEGRPLWLGSLKSNIGHAQAAAGIASVIKTVMALRHGRLPKTLHAEQPTSQVNWT
SGAVSLLAEARAWPETGHARRAGISSFGVSGTNAHVILEQAPEEAEATGENTADQEPPVR
SAESADPGPVATGHVVPWLLSGHTQEALRAQAARLLTQVRETPSDSPRDVGWSLATTRTR
LDHRAVVLCADAEQAVAGLEAVASGTSARSAVTGSVASGKVAVLFTGQGSQRAGMGRELH
GAHPVFARAFDAVCAQFGDLRDGDDKVSLAEVIFAEEGSATAALLDRTEFTQPALFALEV
ALFRLVESWGVRPAYVLGHSIGEVAAAHVAGVLSLPDACTLVRARGRLMQQLTATGAMVA
VEAAEDEVAPLLAGKEHKVSIAAVNGPASVVVSGDEDVVTAVAETLARQGRKTKRLVVSH
AFHSPHMDGMLDAFREVASRLAYAPPRIPVVSNLTGAVADPEELCSPEYWVRHARGAVRF
LDGVRTLADEGVRTHLELGPDGVLTAMGQDCLPEADAAFVPSLRPGVQEPHAVLAGLAGL
YVRGVRVDWDAMFAGSGARPVALPTYAFQHEHYWLERAAGSGDVGAVGLGEAGHPLLGAV
VQLPETGGVQLSGRLSVRAQPWLGEHVISGAVLVPGTAMVELAVRAGDETGTPVLEELVI
GQPMVLPGDTALSVQVVVGADEGGRRTVRIYSRTDGGTDWTEHATGTLAAQGPAPLDGAA
GGAAVEWPPAEAEPIPVEDFYRSLVDAGYAYGPAFRGLVAAWRRDGEIFGDVALPEASVA
EAERFGIHPALLDAALHAGSFCLPSDPARQVTLLPFAWNTVRLHAGGASAVRVHVRPVGD
DAFSVRLTDGSGQTVASVDSLTLRAVDPAQLKIGTADDALWTVRWSETSLPDGAVSWAPL
GESATGATGGYGATGDGGGPGGALPDVLVADTRAWAEDLTGPPTARARELTGRLLEEIQR
WVADDAMAGTRLAVVTRGAVAVHDDTEVTDPAATALWGLVRSAQAEHPGRVALVDADGAC
EELPAGVWSGDEPQLAVRGGAVWVPRLTRVEPGLRVPAQASWHLDSAEYGTLDNLALLPD
EAEPAPPAAGQVRIEVRAAGLNFRDVLVALGMYPGRSVIGTEGAGVVTEVGPGVTGLAVG
DRVMGLFSGSFGPLATADARTVIRMPEGWSFGTAAGVPVAYLTALYALQDLGRVQPGETV
LVHAAAGGVGMAAVQLAQHFGATVLGTAHPSKHHALHRLGVPAERLASSRDLAYADTFPT
ADVVLNSLTGEHIDASLGLLNPGGRFLEMGKTDLREPGEVGARHPEVTYRAFDLGGEAPA
ERVRELLHQLVELFEAGRIEPLPVRQWDITRAPEAFRWMSQGRHTGKIVLTLPRALDPDG
TVLVTGGTGTLGATIARHLLTQHGARHLLLVSRRGPDAPGATDLTTELTELGATVRITAC
DTADRDQLAALLADIPADHPLTAVVHTAGTLDDGVLTALTPDRLDTVFRPKVDAVTHLHD
LTRDHDLAAFVVYSSAAGVLGGPGQGNYSAANAYLDGLAQWRRAHGLPATSLAWGMWAQT
SGMTAGLGSGDLHRVRRGGIVGLSTAEALDLFDRSVASGLSLLVPLRLDIAALGAEAAEP
PPLLRGLVRPARRTARPVPKAGEGGLAERLAGLSAAEQERLLIELIREQAASVLGFPTVD
PIGPEQAFRDMGFDSLTAVELRNRLNTATGLRLPATLVFDHPSPLATAEFLRDQLGGRAV
EAAPRPARRDRSAPDGAEDPVVVVGMGCRLPGDVRSPEDLWRLIATGTDAIGPFPQDRGW
DLAGLFDSDPDAQGKSYVREGGFLTDAGGFDATFFGISPREALSMDPQQRVLLETAWETL
ERSGIVPTSLRGQEVGVFVGASGQGYGTGPGAAPEGLEGYLGVGGATSVASGRVSYTFGL
TGPAVTVDTACSSSLVALHLAAQALRSGECTMALAGGVAVMGQPGAFVEFSRQRGLASDG
RCKSFGEGADGTNWSEGVGLVLLERLSDARRNGHEVLAVIRGTAVNQDGASNGLTAPNGP
SQQRVIRQALANAGLTVADVDAVEAHGTGTALGDPIEAQALLATYGQDRPGDEPLWLGSL
KSNIGHAQAAAGVASVIKMVLAIRQGTLPRSLHINEPTTQVDWTSGAVCLLTDARPWPET
GHPRRAGISSFGVSGTNAHLILEQAPQPEPEPASKADEGTDTPGLVTTGGTTPWVLSAKT
PAALRAQARRLLDHLESDMDAHPVDIGWSLATTRTLHDHRAVVITDTEADSDEAAAALTA
LATGQPHPRLTTGHATTHGKTVFVFPGQGAQWVGMGAQLLKTSPVFAERLHECAAALAPY
TDWSLIDVITGTPDAPSLERVDVVQPATFAVVVSLAALWQSVGIHPDAVIGHSQGEIAAA
CVAGHLTLTNAAKIVTLRSQTIAHHLAGHGGMMSVLTSREQVEEALTPWHGKLWIAAHNS
PNATVIAGDTDALHQLHTHYTDQGIRARIIPVDYASHTGHVDTIKNQLHQTLADTTTEPG
TIPWLSTVTGQWIEPDTVDSGYWYRNLRQTVQFEHTIHTLANDGYRTFIEISPHPVLTTA
IQETLEANDTPNTTITGTLRRDDDTPTRFLTHLAELSTRGTPMDWPTAYTGSQPSQIPLP
TYPFEHETFWLDRGGPGDVRAVGLEDTGHPLVGAVVSVPDTGGVLLTGRLSLRSHPWLAD
HAVSGTVLLPGTAMVELAVRAGDEADTSTLEELVISRPMTVPDEGTLHVQVLVGGEDRGR
RKVGVYSRPEGTRQWTEHATGTLTGRATGTLTAGATAPPPEAAQPWPPEGSEPVALEGFY
EHLAEVGYEYGPAFRGLRAVWKRDDEVFAEVSVPEEQTGVAGRFGIHPALLDATLHAGNF
CFQSDGERPTMLPFAWTDVRLHAVGATTVRVRATVSDGDGLCVRISDPQGVPVATIGSLQ
LRETTPDQLRALSAASGGNALWAVDWAECGLDATEARWATLGESRLPDSPPSYPDLSTAV
EAVESAEAGERPAVLVADVSAWVPEKTGPIDRTHALCARVLDLLRQWVDRRELADTHLVV
LTHGAMAAHDTAEVTDPAAAAVWGLVRSAQSEHPGRIRLIDIDDHSHQALPTALATTEAQ
LALRDATAYTPHLTPAPATTPEPLTLDPEGTVLITGGTGTLGALTARHLITHHHARHLLL
VSRQGPDAPGATDLTTELTELGATVHITACDTADRDQLAALLADIPAAHPLTAVVHTAGT
LDDALLTDLTPQRLDTVFRPKVDALTHLHDLTRDHDLTAFVIYSSATGTLGTPGQANYAA
ANTYADALAHQRHATGLPATSLAWGLWETTSSLTAGMTATQQQRTRDSGVVPLTDADGMR
LLDTALATRHPHLVPLELDLAALQNNTGPHTLPPLLRTLIRGHHRPTAHTTAQPEDDAPS
LAEQLAALDPTQRHQRLTALVRAEAAAVLGHPTPDAVGPDDALFEIGFDSLTAVELRNRL
NAATGLQLAAAMLFDYPTPSMAAEHLQEQLALDAATTETHVAAREAAEDDDQSTER
selected fasta
>polyketide synthase [GdmAIII]
ATGGCTGCGTCCCGGGAAGACCTGGTCAAGGCGCTGCGTACCTCGCTGATGGACGCCGAG
CGGCTGAAGCGGGAGAACGACCGGCTGATCGCCGAGTCCACCGAACCGGTGGCGATCGTG
GCGATGGCGTGCCGGCTGCCGGGTGGGGTGACCGACCCGGAGTCGCTGTGGGAGCTGGTG
GACGAGGGGCGGGACGCGATCGGGCCGTTCCCCACGGATCGCGGCTGGGACCTGGAGACC
CTGTTCGACTCCGATCCGGACGCCGTGGGCAAGTCCTACGTACGCGAGGCGGGGTTCCTG
GAGGGGGCGGGCGGATTCGACGCCGCCTTCTTCGGCATCTCGCCGCGCGAGGCCCTGTCG
CTGGACCCGCAGCAGCGGCTGCTGCTGGAGACCGCGTGGGAGACCTTCGAGCGGGCGGGG
ATGGATCCGCGGTCGGTGGAGGGCCGGGACATCGCGGTGTTCGCCGGGGGCAGCGGCCAG
GGGTACGGCGGCGGTCCGGGTGAGGCGCCCAAGGGCCTGGAGGGCTATCTGGGGGTCGGC
GCTTCCGGCAGTGTCATCTCCGGGCGCGTGTCGTACACGCTCGGGCTGACCGGTCCCGCC
GTGACCGTGGACACCGCCTGCTCGTCCTCGCTGGTGGCCGCCCATCTCGCCGTGCAGGCG
CTGCGGTCCGGCGAATGTTCCATGGCGCTGGCCGGTGGTGTCGCCGTGATGGGCCAGCCC
ACCGCCTTCGTCGAGTTCTCCCGGCAGCGTGGCCTGGCGCCCGACGGGCGCTGCAAGTCC
TTCGGCGCGGGCGCCGACGGCACCACCTGGTCCGAAGGTGTCGGGCTCGTTCTGCTGGAG
CGGCTGTCGGACGCCCGCCGCAACGGCCACGAAGTGCTGGCCGTGATCCGGGGCACCGCG
GTCAACCAGGACGGCGCCTCCAACGGACTCACCGCGCCCAACGGCCCCTCCCAGGAGCGG
GTGATCCGCCAGGCCCTGTCCAACGCCGGGCTGACGGTGGCCGACGTGGACGCCGTCGAG
GCCCACGGCACCGGCACCGCCCTCGGCGACCCCATCGAAGCCCAGGCCGTTCTCGCCACC
TACGGCCAAAGCCGCCCGGAGGGCCGGCCGCTGTGGCTCGGCTCCCTCAAGTCCAACATC
GGCCACGCGCAGGCCGCAGCGGGCATCGCCAGTGTCATCAAGACCGTCATGGCCTTACGC
CACGGCCGGTTGCCGAAGACCCTCCACGCCGAACAGCCCACCTCCCAGGTGAACTGGACG
TCGGGCGCGGTGTCCCTGCTCGCCGAGGCGCGGGCGTGGCCGGAGACCGGACACGCCCGC
CGCGCCGGGATCTCCTCCTTCGGCGTCAGCGGGACGAACGCACACGTCATCCTGGAACAG
GCCCCTGAGGAAGCCGAGGCGACCGGGGAGAACACCGCCGATCAGGAACCGCCCGTACGC
TCGGCGGAGTCCGCCGACCCCGGCCCGGTCGCCACCGGCCACGTGGTGCCGTGGCTGCTC
TCGGGCCATACGCAGGAGGCGCTGCGTGCCCAGGCCGCCCGGCTGCTGACCCAGGTGCGC
GAGACGCCCTCCGACAGTCCGCGGGACGTGGGCTGGTCACTGGCCACCACCCGGACCCGG
CTGGACCACCGCGCGGTCGTACTGTGCGCCGATGCCGAGCAGGCCGTCGCGGGGCTGGAG
GCGGTGGCCTCGGGCACGTCCGCCCGGTCGGCGGTCACCGGGTCCGTGGCCTCCGGAAAG
GTGGCGGTGCTGTTCACCGGGCAGGGCAGCCAGCGGGCCGGAATGGGCCGCGAACTGCAC
GGCGCCCACCCGGTGTTCGCGCGGGCCTTCGACGCCGTGTGCGCCCAGTTCGGCGACCTG
CGCGACGGGGACGACAAGGTCTCGCTGGCCGAGGTGATCTTCGCCGAGGAGGGGTCGGCG
ACGGCAGCGCTGCTGGACCGGACCGAGTTCACCCAGCCCGCGCTGTTCGCGCTGGAGGTG
GCGCTGTTCCGGCTCGTGGAGTCGTGGGGAGTGCGCCCCGCGTATGTGCTGGGCCACTCG
ATCGGCGAAGTGGCGGCGGCCCATGTGGCCGGGGTCCTGTCCCTGCCGGACGCCTGCACA
TTGGTGCGGGCGCGCGGGCGGCTGATGCAGCAACTCACCGCGACCGGGGCGATGGTCGCG
GTGGAGGCGGCCGAGGACGAGGTGGCGCCGCTGCTCGCGGGGAAGGAGCACAAGGTCTCC
ATCGCCGCGGTCAACGGCCCGGCCTCCGTGGTCGTCTCCGGTGACGAGGACGTGGTCACG
GCGGTGGCGGAGACGCTGGCGCGGCAGGGCCGCAAGACCAAGCGGCTCGTGGTCTCGCAC
GCCTTCCACTCCCCCCACATGGACGGGATGCTGGACGCGTTCCGCGAGGTGGCGTCGCGG
CTGGCCTACGCGCCACCCCGGATACCCGTGGTGTCGAACCTCACCGGCGCGGTCGCCGAT
CCCGAGGAGCTGTGCTCCCCCGAGTACTGGGTACGGCATGCACGTGGCGCGGTGCGGTTC
CTCGACGGTGTCCGCACACTGGCCGACGAGGGCGTGCGCACCCATCTGGAACTCGGCCCG
GATGGGGTGCTGACCGCGATGGGGCAGGACTGTCTGCCCGAGGCGGACGCGGCGTTCGTG
CCGTCCCTGCGTCCGGGCGTCCAGGAGCCGCACGCGGTGCTGGCCGGGCTCGCCGGCCTG
TACGTACGGGGTGTGCGGGTGGACTGGGACGCGATGTTCGCCGGGTCCGGCGCCCGGCCC
GTCGCCCTTCCCACGTACGCCTTCCAGCACGAGCACTACTGGCTGGAGCGGGCCGCCGGC
TCCGGCGACGTGGGCGCGGTGGGGCTCGGCGAGGCGGGCCATCCGCTGCTGGGCGCGGTG
GTGCAGCTCCCGGAGACGGGCGGGGTGCAGCTCAGCGGGCGGCTGTCGGTACGGGCCCAG
CCCTGGCTGGGCGAACACGTCATCTCCGGGGCGGTGCTGGTGCCCGGCACCGCCATGGTG
GAACTGGCCGTCCGCGCCGGGGACGAGACCGGCACCCCGGTGCTGGAGGAGCTGGTGATC
GGGCAGCCGATGGTGCTGCCCGGCGACACCGCCCTCAGTGTCCAGGTCGTCGTGGGCGCG
GACGAGGGCGGGCGGCGTACGGTGCGGATCTACTCCCGTACCGACGGGGGCACCGACTGG
ACCGAGCACGCCACCGGCACGCTCGCGGCGCAGGGCCCGGCACCGCTGGACGGGGCCGCG
GGCGGGGCCGCCGTCGAGTGGCCGCCCGCGGAAGCCGAGCCGATCCCCGTGGAGGACTTC
TACCGCTCGCTCGTCGACGCCGGATACGCGTACGGACCGGCGTTCCGCGGGCTCGTCGCC
GCGTGGCGCCGGGACGGTGAGATCTTCGGCGATGTGGCGCTGCCGGAGGCGTCCGTCGCG
GAGGCCGAGCGGTTCGGCATCCACCCGGCGCTGCTGGACGCCGCACTGCACGCGGGCAGC
TTCTGTCTGCCCTCCGACCCGGCGCGACAGGTGACCCTGCTGCCGTTCGCCTGGAACACC
GTGCGTCTGCACGCGGGCGGCGCGTCCGCGGTCCGGGTGCATGTCCGCCCGGTCGGCGAC
GACGCCTTCTCGGTACGCCTGACCGACGGCTCGGGCCAGACGGTGGCCTCGGTGGACTCG
CTCACCTTGCGGGCGGTGGACCCGGCCCAGCTCAAGATCGGCACGGCCGACGACGCGCTG
TGGACGGTCCGCTGGAGCGAGACCTCGCTGCCGGACGGCGCGGTCTCCTGGGCCCCGCTC
GGCGAGTCGGCCACCGGGGCAACCGGGGGCTACGGCGCCACAGGGGACGGCGGAGGCCCA
GGGGGCGCGCTTCCCGACGTCCTCGTGGCCGATACGCGCGCCTGGGCCGAAGACCTCACC
GGACCGCCGACCGCGCGGGCCCGGGAGCTCACCGGCCGCCTGCTGGAGGAGATCCAGCGG
TGGGTCGCCGACGACGCCATGGCCGGGACGCGGCTCGCCGTGGTCACCCGCGGCGCGGTC
GCGGTCCACGACGACACCGAGGTCACCGACCCGGCCGCCACCGCGCTCTGGGGCCTGGTC
CGCTCGGCCCAGGCCGAACACCCGGGGCGGGTGGCCCTGGTGGATGCCGACGGAGCGTGC
GAGGAACTGCCCGCCGGGGTGTGGTCCGGGGACGAGCCCCAACTGGCGGTGCGCGGTGGC
GCCGTGTGGGTGCCACGCCTCACCCGGGTCGAGCCCGGCCTGCGCGTGCCCGCGCAGGCG
TCGTGGCATCTGGACTCGGCCGAGTACGGCACCCTGGACAATCTGGCGCTGCTGCCCGAC
GAGGCCGAGCCCGCACCGCCGGCGGCCGGTCAGGTGCGGATCGAGGTCCGCGCCGCCGGG
CTCAACTTCCGGGATGTCCTGGTGGCTCTCGGCATGTATCCGGGCCGGTCGGTGATCGGC
ACGGAGGGCGCCGGTGTGGTGACCGAAGTCGGTCCGGGCGTCACGGGCCTGGCCGTGGGC
GACCGGGTGATGGGCCTGTTCTCCGGCTCGTTCGGACCGCTGGCCACCGCCGACGCGCGC
ACGGTGATCCGGATGCCGGAGGGCTGGTCGTTCGGCACGGCGGCCGGGGTGCCGGTGGCC
TATCTGACGGCGCTGTACGCGTTGCAGGACCTCGGGAGGGTCCAGCCGGGCGAGACGGTC
CTGGTGCACGCCGCCGCGGGCGGTGTGGGCATGGCCGCCGTCCAGCTCGCACAGCACTTC
GGCGCCACCGTCCTGGGCACCGCCCACCCCTCCAAGCACCACGCACTCCACCGGCTGGGC
GTTCCCGCCGAACGGCTCGCCTCCAGCCGCGACCTCGCCTACGCCGACACCTTCCCCACC
GCCGACGTCGTCCTCAACTCCCTCACCGGCGAGCACATCGACGCCTCCCTCGGACTTCTC
AACCCCGGCGGCCGGTTCCTGGAGATGGGGAAGACCGACCTGCGGGAGCCCGGCGAGGTC
GGGGCGCGGCATCCGGAGGTCACCTACCGGGCGTTCGATCTCGGTGGGGAGGCCCCCGCG
GAGCGGGTGCGGGAGTTGCTGCACCAGTTGGTGGAGCTGTTCGAGGCGGGCCGGATCGAG
CCGCTGCCGGTACGGCAGTGGGACATCACCCGCGCCCCCGAGGCGTTCCGCTGGATGAGT
CAGGGGCGGCATACCGGCAAGATCGTGCTCACCCTGCCACGCGCCCTGGACCCGGACGGC
ACCGTCCTGGTCACCGGTGGCACGGGCACCCTCGGCGCCACGATCGCCCGCCACCTTCTC
ACCCAGCACGGCGCACGCCATCTGCTGCTGGTCAGCCGCCGGGGACCGGACGCACCTGGC
GCCACAGACCTGACCACCGAACTCACCGAACTCGGCGCCACCGTCCGCATCACCGCCTGC
GACACCGCCGACCGCGACCAACTCGCCGCGCTCCTCGCCGACATCCCCGCCGACCACCCC
CTCACCGCCGTGGTCCACACGGCCGGGACCCTCGACGACGGTGTCCTGACCGCGCTCACC
CCGGACCGCCTCGACACCGTCTTCCGCCCCAAGGTCGACGCCGTCACCCATCTCCACGAC
CTCACCCGCGACCACGACCTGGCGGCGTTCGTGGTGTACTCGTCCGCCGCCGGAGTCCTC
GGCGGGCCCGGCCAGGGCAACTACTCCGCCGCCAACGCCTATCTGGACGGACTCGCACAG
TGGCGGCGTGCGCACGGGCTCCCCGCCACCTCGCTGGCGTGGGGCATGTGGGCGCAGACC
AGTGGCATGACGGCCGGGCTCGGCTCCGGCGATCTGCACCGGGTGCGGCGTGGCGGCATC
GTCGGGCTGTCCACGGCGGAGGCCCTGGACCTGTTCGACCGGTCGGTGGCGTCCGGGCTG
TCCCTGCTGGTGCCGTTGCGGTTGGACATCGCCGCCCTCGGTGCGGAGGCCGCGGAACCG
CCGCCGCTGCTGCGGGGTCTGGTCCGGCCGGCCCGGCGTACGGCCCGGCCGGTGCCGAAG
GCCGGTGAGGGCGGCCTCGCCGAACGGCTGGCCGGGCTGTCGGCGGCCGAACAGGAGCGT
CTGCTCATCGAGTTGATCCGCGAACAGGCCGCTTCGGTGCTCGGGTTCCCCACGGTCGAC
CCGATCGGGCCGGAGCAGGCGTTCCGCGACATGGGGTTCGACTCGCTGACCGCGGTGGAG
CTGCGCAACCGCCTCAACACGGCCACCGGGCTACGGCTCCCCGCAACGCTGGTCTTCGAC
CACCCGAGCCCCTTGGCCACCGCCGAGTTCCTGCGGGATCAACTGGGCGGGCGCGCGGTC
GAGGCGGCGCCCCGCCCGGCCCGGCGTGACCGGTCGGCTCCGGACGGGGCCGAGGATCCG
GTCGTCGTGGTCGGCATGGGCTGCCGCCTGCCCGGCGACGTCCGCAGCCCCGAGGACCTG
TGGCGGCTGATCGCCACCGGAACCGACGCGATCGGGCCGTTCCCGCAGGACCGGGGCTGG
GACCTGGCCGGGCTCTTCGACTCCGACCCGGACGCACAGGGCAAGTCCTACGTACGCGAG
GGCGGTTTCCTCACCGACGCGGGCGGCTTCGACGCCACGTTCTTCGGCATCTCCCCACGC
GAGGCCCTGTCGATGGACCCGCAACAGCGCGTCCTGCTGGAGACCGCGTGGGAGACCCTG
GAACGCTCCGGGATCGTTCCCACGTCACTGCGCGGACAGGAGGTCGGGGTCTTCGTCGGG
GCCAGTGGCCAGGGGTACGGCACCGGCCCGGGCGCGGCGCCGGAAGGCTTGGAGGGCTAT
CTCGGGGTCGGCGGTGCGACGAGCGTGGCATCGGGCCGGGTGTCGTACACCTTCGGCCTG
ACCGGTCCGGCGGTCACGGTGGACACGGCGTGCTCCTCCTCGCTGGTGGCCCTCCACCTC
GCCGCGCAAGCCCTGCGCTCCGGCGAATGCACGATGGCACTCGCCGGCGGCGTCGCCGTC
ATGGGCCAGCCCGGCGCCTTCGTCGAGTTCTCGCGCCAGCGCGGTCTCGCGTCCGACGGC
CGCTGCAAGTCCTTCGGCGAGGGCGCCGACGGCACCAACTGGTCCGAGGGTGTTGGTCTG
GTGCTGCTGGAACGGCTCTCCGACGCCCGCCGCAACGGCCACGAGGTGCTGGCCGTGATC
CGTGGCACGGCGGTGAACCAGGACGGCGCGAGCAACGGCCTCACCGCGCCCAACGGACCC
TCCCAGCAGCGAGTGATACGGCAGGCGCTGGCGAACGCCGGGCTGACGGTGGCCGACGTG
GACGCGGTCGAGGCCCACGGCACCGGCACCGCCCTCGGCGACCCCATCGAGGCCCAGGCA
CTCCTGGCCACCTACGGCCAGGACCGGCCGGGGGACGAACCGCTGTGGCTCGGTTCGCTG
AAGTCCAACATCGGGCATGCCCAAGCGGCCGCAGGCGTGGCCAGCGTCATCAAGATGGTG
CTGGCGATACGGCAGGGCACGCTTCCGCGGTCCTTGCACATCAACGAACCCACCACCCAG
GTGGACTGGACGTCCGGTGCGGTGTGCCTGCTCACCGATGCCCGCCCCTGGCCGGAGACC
GGCCACCCCCGCCGTGCCGGGATCTCCTCCTTCGGAGTCAGCGGCACCAACGCCCATCTC
ATCCTGGAGCAGGCACCTCAGCCCGAGCCCGAGCCCGCATCGAAGGCGGACGAGGGCACG
GACACCCCTGGGCTGGTCACCACCGGCGGAACCACCCCCTGGGTGCTGTCCGCCAAGACC
CCGGCAGCTCTGCGGGCTCAGGCCCGACGCCTGCTGGACCATCTGGAATCCGACATGGAC
GCACACCCAGTGGACATCGGCTGGTCACTCGCCACCACCCGCACCCTCCACGACCACCGC
GCCGTCGTCATCACCGACACCGAAGCCGATAGCGACGAAGCCGCAGCTGCTCTCACCGCC
CTCGCGACCGGACAACCCCACCCCCGCCTCACCACCGGCCACGCCACCACCCACGGCAAA
ACAGTGTTCGTGTTCCCTGGCCAAGGCGCCCAATGGGTGGGCATGGGAGCCCAACTCCTC
AAGACTTCCCCCGTCTTCGCCGAACGTCTCCACGAATGCGCCGCGGCCCTGGCCCCGTAC
ACCGACTGGTCGCTCATCGACGTCATCACCGGCACGCCCGACGCTCCCTCGCTCGAGCGT
GTCGACGTCGTACAGCCCGCCACCTTCGCCGTCGTCGTCTCCCTCGCCGCACTCTGGCAA
TCCGTGGGCATCCACCCCGACGCCGTCATCGGCCACTCCCAAGGCGAAATCGCCGCCGCC
TGCGTCGCCGGACACCTCACCCTCACCAACGCCGCCAAAATCGTCACCCTCCGCAGCCAG
ACCATCGCCCACCACCTCGCCGGACACGGCGGCATGATGTCCGTCCTCACCTCCCGGGAA
CAGGTCGAGGAAGCCCTCACCCCGTGGCACGGCAAACTCTGGATCGCCGCACACAACAGC
CCCAACGCCACCGTCATCGCAGGCGACACCGACGCCCTGCACCAACTCCACACCCACTAC
ACCGACCAGGGCATCAGGGCCCGCATCATCCCCGTCGACTACGCCTCCCACACCGGACAC
GTCGACACCATCAAAAACCAACTCCACCAGACCCTGGCCGACACCACGACCGAGCCCGGC
ACCATCCCCTGGCTCTCCACCGTCACCGGACAGTGGATCGAACCCGACACCGTCGACAGC
GGCTACTGGTACCGCAACCTCCGCCAAACCGTGCAATTCGAGCACACCATCCACACCCTC
GCCAACGACGGCTACCGCACCTTCATCGAAATCAGCCCCCACCCCGTCCTCACCACCGCC
ATCCAAGAAACCCTCGAAGCCAACGACACCCCCAACACCACCATCACCGGCACCCTCCGC
CGCGACGACGACACCCCCACCCGCTTCCTCACCCACCTCGCCGAACTGTCCACCAGGGGA
ACACCAATGGACTGGCCCACCGCGTACACCGGATCACAACCCTCCCAAATCCCGCTCCCC
ACCTACCCCTTCGAGCACGAGACGTTCTGGCTGGACCGCGGCGGTCCGGGCGACGTCCGT
GCCGTGGGGCTGGAGGACACCGGCCATCCGCTGGTCGGGGCCGTGGTGAGCGTGCCCGAC
ACCGGAGGTGTGCTGCTCACCGGACGTCTCTCCCTGCGCAGCCACCCCTGGCTGGCCGAC
CACGCCGTCTCCGGCACCGTCCTGCTCCCGGGTACGGCGATGGTCGAGCTGGCGGTGCGC
GCCGGGGACGAGGCGGACACCTCCACCCTGGAAGAGCTGGTCATCAGCCGGCCGATGACG
GTGCCGGACGAGGGCACTCTGCACGTCCAGGTGCTCGTCGGTGGCGAGGACCGCGGGCGC
CGCAAGGTGGGGGTCTACTCGCGCCCGGAGGGCACACGGCAGTGGACCGAGCACGCCACC
GGCACCCTGACCGGACGGGCTACCGGCACCCTGACCGCAGGGGCCACGGCCCCGCCGCCC
GAGGCCGCTCAGCCGTGGCCGCCCGAGGGCTCGGAGCCCGTCGCCCTCGAGGGATTCTAC
GAGCATCTGGCCGAGGTCGGGTACGAGTACGGCCCGGCTTTCCGCGGTCTGAGGGCGGTG
TGGAAGCGGGACGACGAGGTGTTCGCCGAAGTGTCCGTGCCGGAGGAGCAGACCGGGGTC
GCCGGGCGGTTCGGCATCCACCCGGCGCTGCTGGACGCCACCCTGCACGCCGGGAACTTC
TGCTTCCAGTCCGATGGTGAGCGGCCCACGATGCTGCCGTTCGCATGGACCGATGTGCGG
CTCCACGCCGTGGGCGCAACCACCGTGCGGGTGCGGGCGACGGTGTCCGACGGGGACGGG
CTGTGCGTACGGATCTCCGATCCGCAGGGCGTACCGGTCGCCACGATCGGCTCCCTCCAG
CTCCGGGAGACCACACCCGACCAGTTGCGCGCCCTGTCCGCCGCATCGGGCGGCAATGCG
CTGTGGGCGGTCGACTGGGCCGAGTGCGGGCTCGATGCCACGGAAGCGCGGTGGGCCACG
CTCGGGGAGAGTCGGCTCCCGGATTCCCCGCCGAGCTACCCCGATCTCTCCACGGCTGTG
GAGGCCGTGGAAAGCGCGGAGGCCGGAGAGCGGCCCGCCGTGCTCGTCGCCGACGTGTCC
GCCTGGGTTCCGGAGAAGACCGGACCCATCGACCGTACGCACGCGCTCTGTGCCCGGGTC
CTGGATCTGCTGCGGCAATGGGTGGACCGGCGCGAACTCGCGGACACCCACCTGGTCGTC
CTCACCCACGGCGCCATGGCCGCCCACGACACCGCCGAGGTCACCGACCCGGCCGCGGCC
GCCGTCTGGGGCTTGGTCCGCTCGGCCCAGTCCGAGCACCCCGGCCGTATCCGGCTCATC
GACATCGACGACCACTCCCACCAGGCCCTGCCCACCGCACTCGCCACCACCGAGGCCCAA
CTCGCCCTCCGCGACGCCACCGCCTACACCCCCCATCTGACGCCCGCACCCGCCACCACG
CCCGAGCCCCTCACCCTCGACCCCGAGGGCACCGTCCTCATCACCGGCGGCACCGGCACC
CTCGGCGCCCTCACCGCCCGCCACCTCATCACCCACCATCACGCACGCCATCTCCTCCTG
GTCAGCCGCCAGGGCCCCGACGCGCCCGGCGCCACGGACCTCACCACCGAACTCACCGAA
CTCGGCGCCACCGTCCACATCACCGCCTGCGACACCGCCGACCGCGACCAACTCGCCGCC
CTCCTCGCCGACATCCCGGCCGCCCACCCCCTCACCGCCGTCGTCCACACCGCCGGAACC
CTCGACGACGCCCTGCTCACCGACCTCACCCCGCAGCGCCTCGACACCGTCTTCCGCCCC
AAGGTCGACGCCCTCACCCACCTCCACGACCTCACCCGCGACCACGACCTGACCGCCTTC
GTCATCTACTCCTCCGCCACCGGCACCCTCGGCACCCCCGGCCAGGCCAACTACGCCGCC
GCCAACACCTACGCCGACGCCCTCGCCCACCAGCGCCACGCCACCGGACTCCCCGCCACC
TCCCTCGCCTGGGGCCTATGGGAAACCACCAGCAGCCTCACCGCCGGCATGACCGCCACC
CAGCAGCAACGCACCCGCGACAGCGGCGTCGTTCCCCTGACCGACGCCGACGGCATGCGC
CTCCTCGACACCGCGCTCGCCACCCGCCACCCTCATCTCGTCCCCCTCGAACTCGACCTC
GCCGCCCTCCAGAACAACACCGGCCCGCACACCCTCCCGCCCCTGCTGCGCACCCTCATA
CGCGGCCACCACCGCCCCACCGCCCACACCACAGCCCAGCCCGAGGACGACGCCCCGTCC
CTGGCCGAGCAGCTGGCCGCCCTCGACCCGACCCAGCGGCACCAGCGCCTCACCGCGCTT
GTCCGCGCCGAAGCCGCGGCCGTCCTCGGACACCCCACCCCGGACGCGGTGGGGCCGGAC
GACGCCCTCTTCGAGATCGGGTTCGACTCGCTGACCGCGGTGGAACTGCGCAACCGCCTC
AACGCGGCCACCGGCCTCCAGCTCGCCGCGGCGATGCTGTTCGACTACCCAACCCCGTCG
ATGGCCGCCGAGCACCTCCAGGAACAGCTCGCGCTGGACGCGGCCACCACGGAAACACAC
GTGGCGGCCCGGGAAGCGGCGGAAGACGACGACCAGAGCACGGAGAGGTGA
[6] KS35..410
[6] AT584..907
[6] malonyl-CoA780..784
[6] DH954..1118
[6] ER1430..1730
[6] KR1740..1920
[6] ACP2022..2092
[7] KS2119..2494
[7] AT2662..2981
[7] methylmalonyl-CoA2854..2858
[7] DH3029..3197
[7] KR3510..3690
[7] ACP3797..3867
[6] KS103..1230
[6] AT1750..2721
[6] malonyl-CoA2338..2352
[6] DH2860..3354
[6] ER4288..5190
[6] KR5218..5760
[6] ACP6064..6276
[7] KS6355..7482
[7] AT7984..8943
[7] methylmalonyl-CoA8560..8574
[7] DH9085..9591
[7] KR10528..11070
[7] ACP11389..11601

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR001227 Acyl transferase domain (Domain)
[576-712] G3DSA:3.40.366.10 [780-894] G3DSA:3.40.366.10 [2652-2785] G3DSA:3.40.366.10 [2854-2971] G3DSA:3.40.366.10
G3DSA:3.40.366.10   Ac_transferase_reg
IPR002198 Short-chain dehydrogenase/reductase SDR (Family)
[1740-1907] 1.29999999999998e-64 PF00106
PF00106   adh_short
IPR006162 Phosphopantetheine attachment site (PTM)
[2050-2065] PS00012 [3825-3840] PS00012
PS00012   PHOSPHOPANTETHEINE
IPR009081 Acyl carrier protein-like (Domain)
[2022-2092] PS50075 [3797-3867] PS50075
PS50075   ACP_DOMAIN
[2025-2091] 1.2e-12 PF00550 [3801-3866] 1e-13 PF00550
PF00550   PP-binding
[2022-2096] 9.40000000000003e-44 G3DSA:1.10.1200.10 [3795-3870] 9.40000000000003e-44 G3DSA:1.10.1200.10
G3DSA:1.10.1200.10   ACP_like
[2015-2135] 1.39999892049878e-25 SSF47336 [3790-3888] 3.89999861795218e-22 SSF47336
SSF47336   ACP_like
IPR011032 GroES-like (Domain)
[1424-1575] 1.3000049540733e-34 SSF50129
SSF50129   GroES_like
IPR013154 Alcohol dehydrogenase GroES-like (Domain)
[1450-1505] 4.2e-09 PF08240
PF08240   ADH_N
IPR013968 Polyketide synthase, KR (Domain)
[3510-3689] 1.2e-61 PF08659
PF08659   KR
IPR014030 Beta-ketoacyl synthase, N-terminal (Domain)
[35-285] 2.30000000000004e-92 PF00109 [2119-2369] 3.79999999999991e-93 PF00109
PF00109   ketoacyl-synt
IPR014031 Beta-ketoacyl synthase, C-terminal (Domain)
[293-410] 8.30000000000004e-47 PF02801 [2377-2494] 1e-47 PF02801
PF02801   Ketoacyl-synt_C
IPR014043 Acyl transferase (Domain)
[584-907] 3.10000000000005e-65 PF00698 [2662-2981] 1.29999999999998e-104 PF00698
PF00698   Acyl_transf_1
IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase (Domain)
[580-890] 4.10001399699315e-73 SSF52151 [2660-2963] 6.80004680300024e-68 SSF52151
SSF52151   Acyl_Trfase/lysoPlipase
IPR016036 Malonyl-CoA ACP transacylase, ACP-binding (Domain)
[714-779] 5.39999384454126e-17 SSF55048 [2788-2853] 5.39999384454126e-19 SSF55048
SSF55048   Malonyl_transacylase_ACP-bd
IPR016038 Thiolase-like, subgroup (Domain)
[37-297] G3DSA:3.40.47.10 [298-465] 1.20000000000001e-127 G3DSA:3.40.47.10 [2121-2381] G3DSA:3.40.47.10 [2382-2548] 1.20000000000001e-127 G3DSA:3.40.47.10
G3DSA:3.40.47.10   Thiolase-like_subgr
IPR016039 Thiolase-like (Domain)
[27-463] 4.10001399699315e-100 SSF53901 [2111-2547] 1.59998835313644e-100 SSF53901
SSF53901   Thiolase-like
IPR016040 NAD(P)-binding domain (Domain)
[1520-1705] 1.99999999999999e-48 G3DSA:3.40.50.720 [1740-1927] 3.60000000000002e-73 G3DSA:3.40.50.720 [3510-3716] 2.70000000000002e-70 G3DSA:3.40.50.720
G3DSA:3.40.50.720   NAD(P)-bd
IPR018201 Beta-ketoacyl synthase, active site (Active_site)
[2282-2298] PS00606
PS00606   B_KETOACYL_SYNTHASE
IPR020801 Polyketide synthase, acyl transferase domain (Domain)
[584-887] 1.3000049540733e-127 SM00827 [2664-2963] 2.1000026783403e-124 SM00827
SM00827   PKS_AT
IPR020806 Polyketide synthase, phosphopantetheine-binding domain (Domain)
[2023-2095] 1.79999754022375e-34 SM00823 [3798-3870] 6.89998448199219e-33 SM00823
SM00823   PKS_PP
IPR020807 Polyketide synthase, dehydratase domain (Domain)
[954-1118] 5.60004908290974e-78 SM00826 [3029-3197] 6.4999795054176e-81 SM00826
SM00826   PKS_DH
IPR020841 Polyketide synthase, beta-ketoacyl synthase domain (Domain)
[37-463] SM00825 [2121-2547] SM00825
SM00825   PKS_KS
IPR020842 Polyketide synthase/Fatty acid synthase, KR (Domain)
[1740-1920] 2.90000354677981e-61 SM00822 [3510-3690] 4.50001022902825e-59 SM00822
SM00822   PKS_KR
IPR020843 Polyketide synthase, enoylreductase (Domain)
[1430-1730] SM00829
SM00829   PKS_ER
SignalP No significant hit
TMHMM No significant hit
Gelda2_00090 Gelda2_00090   Gelda2_00110 Gelda2_00110
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