A4092_00240 : CDS information

Location

Organism	Nonomuraea sp.
Strain	ATCC 39727
Entry name	A40926
Contig	AJ561198
Start / Stop / Direction	45,223 / 42,962 / - [in whole cluster] 45,223 / 42,962 / - [in contig]
Location	complement(42962..45223) [in whole cluster] complement(42962..45223) [in contig]
Type	CDS
Length	2,262 bp (753 aa)

Annotation

Category	4.3 transport
Product	putative ABC transporter permease protein
Product (GenBank)	putative ABC transporter, Dbv18
Gene
Gene (GenBank)	dbv18
EC number
Keyword
Note
Note (GenBank)
Reference	ACC Q7WZ73 PmId [12837387] The gene cluster for the biosynthesis of the glycopeptide antibiotic A40926 by nonomuraea species. (Chem Biol. , 2003) [17873036] Phosphate-controlled regulator for the biosynthesis of the dalbavancin precursor A40926. (J Bacteriol. , 2007) comment [PMID: 12837387](2003) Nonomuraea sp. ATCC39727由来A40926生合成gene clusterの同定論文。 A40926は半合成グリコペプチドdalbavancin (BI397 or MDL 62,397)の前駆体。 dbv ORF18: ABC transporter 配列解析のみ。ORF18は追加ABC-type transporterのtransmembrane partnerであるとされている。 --- [PMID: 17873036](2007) RT-PCRとその産物のシークエンスで、dbv18-dbv19が同時転写されることを確認。リン酸による遺伝子発現への影響がRT-PCRで調査されている。dbv18は影響を受けない。
Family/Domain	FD IPR003838 comment [IPR003838] ABC transporter permease protein domain

Sequence

>putative ABC transporter permease protein [putative ABC transporter, Dbv18]
MAGFGAPFRNSDHVVSKLTNEDAFELVERHGANASPLGRAMLTVRAGDRSYPEMGVGPVA
ESKDLRWQQLTSGRFPERKGEAVVDLWDAQNWDVAVGDRIRIGERATAADFTVVGIVRAP
SPVAQASVYVTWPQLMRWADDPSLGIYTVTVRGAVGPVPETAKVQTPEQEIAARTAQLQN
GVDTWSLLLLLFAGIAVFVSILVIANTFSILLAQRMRDFALLRCVGATRRQVVSSVRREA
AVVGLLSSLAGVLVGAGLGYGLIALIKTLSPITPIAAPAPPAPWLLGGLAIGLTATLVAA
WLPIRRVVRVSPLAALRPDTATDPRTATGRARLVLGVFMLIAGLVLLASAMAWHSTVLML
AGGGSLFTGVLLFGPVLIPRLLEITGTRLGTIGRLATKNAVRNPRRTATTAASLLVGITL
ITAVLTGVAITSEALNERLDGQHPIDAALVSTGKPFSADFLDKVRGTSGVDQAIAVDGAV
ATVSGLDKPIPVVTAPDAQRVAHDGGSFARVEPGVLRLDESAFRQLRLRAGDKVRVTVGD
RRAVLQVSLATGWGLQAVVAPETLARLTDSAAPRAVWIRASADADSTRLVGELGDLAAAA
GANVNDQLEARETENAPLMILTWAIVALLGFSVAIALVGIANTLGLSVLERVREHALLRA
LGLTRRQLRRMLAAEAVLLSLVAAVLGTVIGIGFAWVGYETFVKQALDNATMQVPWPLLA
VVVLVAALAGLLASVLPARRAVRVTPAAGLSFE

>putative ABC transporter permease protein [putative ABC transporter, Dbv18]
ATGGCCGGCTTCGGGGCGCCGTTCCGCAACTCCGACCACGTGGTGTCCAAGCTGACGAAC
GAGGATGCGTTCGAGCTCGTCGAGCGTCATGGCGCGAACGCGTCACCGCTCGGCAGGGCC
ATGCTGACGGTGCGCGCGGGTGACCGGTCCTACCCCGAGATGGGCGTGGGGCCGGTCGCC
GAGTCCAAGGACCTGCGCTGGCAGCAGCTCACCTCGGGCCGTTTCCCCGAGCGCAAGGGC
GAGGCCGTGGTGGACCTGTGGGACGCCCAGAACTGGGACGTCGCCGTCGGCGACCGCATC
CGGATAGGTGAGCGTGCCACGGCAGCCGACTTCACCGTGGTCGGCATCGTGCGGGCGCCT
TCTCCTGTGGCGCAGGCGTCGGTGTACGTCACCTGGCCGCAGCTCATGCGCTGGGCCGAC
GATCCCTCCCTCGGCATCTACACGGTGACGGTGCGCGGCGCGGTCGGTCCGGTGCCCGAG
ACCGCGAAGGTGCAGACCCCGGAGCAGGAGATCGCGGCCCGGACGGCGCAGCTCCAGAAC
GGCGTGGACACCTGGTCACTGCTGCTGCTGCTCTTCGCCGGCATCGCCGTGTTCGTCTCG
ATCCTGGTCATCGCGAACACCTTCTCCATCCTGCTGGCCCAGCGCATGCGCGACTTCGCC
CTGTTGCGCTGCGTCGGTGCGACCCGCCGCCAGGTGGTGAGTTCGGTACGCCGGGAGGCG
GCCGTCGTCGGCCTCCTGTCGTCGCTGGCCGGCGTGCTGGTCGGCGCCGGACTCGGCTAC
GGGCTCATCGCCCTGATCAAGACCCTCTCACCGATCACCCCGATCGCCGCCCCGGCACCG
CCCGCGCCGTGGCTGCTGGGCGGGCTCGCCATCGGGCTGACGGCCACCCTGGTCGCGGCC
TGGCTGCCGATCCGGCGCGTGGTGCGGGTGAGCCCGCTGGCGGCACTGCGTCCCGACACC
GCGACCGACCCGCGTACAGCCACGGGGCGGGCACGGCTGGTGCTCGGCGTCTTCATGTTG
ATCGCCGGGCTCGTCCTGCTCGCGTCGGCGATGGCTTGGCACAGCACGGTGCTCATGCTG
GCCGGCGGCGGTTCGTTGTTCACCGGCGTGCTCCTGTTCGGGCCGGTGCTCATCCCCCGT
CTGCTGGAGATCACCGGTACGCGGCTCGGCACCATCGGGCGGCTCGCGACGAAGAACGCC
GTGCGCAACCCGCGCCGGACCGCCACCACCGCCGCCTCACTGCTGGTCGGTATCACCCTG
ATCACCGCCGTCCTGACCGGCGTCGCCATCACCTCCGAGGCGCTGAACGAGAGACTCGAC
GGCCAGCACCCCATCGACGCCGCGCTGGTCTCGACCGGCAAGCCGTTCTCCGCCGACTTC
CTCGACAAGGTCCGTGGCACTTCCGGGGTGGATCAGGCCATCGCGGTGGACGGCGCCGTC
GCCACGGTCTCCGGCCTCGACAAGCCGATCCCGGTGGTCACCGCGCCGGATGCCCAGCGG
GTGGCCCACGACGGCGGGTCGTTCGCCCGGGTGGAGCCAGGCGTGCTCAGGCTCGATGAG
TCCGCATTCCGCCAGCTGCGCCTGCGGGCCGGTGACAAGGTCAGGGTCACGGTCGGCGAC
CGGCGGGCCGTGCTGCAGGTCTCGCTCGCCACCGGCTGGGGGCTGCAGGCCGTCGTCGCG
CCGGAGACGCTGGCCCGGCTCACCGACTCCGCCGCGCCGCGTGCCGTCTGGATCCGCGCA
TCCGCCGACGCCGACTCGACGCGGCTCGTCGGTGAGCTGGGCGACCTGGCGGCCGCGGCC
GGGGCGAACGTGAACGACCAGCTGGAGGCCCGTGAGACGGAGAACGCGCCGCTGATGATC
CTCACCTGGGCCATCGTCGCGCTGCTCGGCTTCTCCGTGGCGATCGCCCTCGTCGGGATC
GCCAACACCCTGGGCCTGTCCGTTCTCGAGCGTGTTCGCGAACACGCGCTGCTGCGCGCG
CTCGGGCTCACTCGCAGGCAGTTGCGGCGGATGCTGGCCGCCGAGGCCGTGCTGCTCTCC
CTGGTGGCCGCCGTGCTCGGCACCGTGATCGGCATCGGGTTCGCCTGGGTCGGTTACGAG
ACCTTCGTGAAGCAGGCTCTCGACAACGCCACCATGCAGGTCCCCTGGCCACTGCTCGCC
GTCGTCGTCCTCGTCGCCGCCCTGGCGGGGCTCCTGGCCAGTGTTCTCCCGGCACGCCGG
GCCGTCCGGGTGACGCCGGCCGCGGGGCTTTCCTTCGAGTGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR003838 Permease FtsX-like (Domain) PF02687 FtsX IPR025857 MacB-like periplasmic core domain (Domain) PF12704 MacB_PCD
SignalP	No significant hit
TMHMM	Transmembrane 9

A4092_00230 A4092_00250