遺伝子 : Two-component system response regulator VanR (VANRB)

遺伝子情報

ID	NRULE_0280
遺伝子ID	VANRB
作成日	2014/07/09
タンパク質名	Protein name Full Two-component system response regulator VanR
遺伝子名	vanRB
遺伝子条件	BLASTP; Q47744; hit=1; score=1000; pid=90
参照	Gene Ontology GO GO:0005737, C:cytoplasm, IEA:UniProtKB-SubCell GO:0003677, F:DNA binding, IEA:UniProtKB-KW GO:0000156, F:phosphorelay response regulator activity, IEA:InterPro GO:0006355, P:regulation of transcription, DNA-templated, IEA:UniProtKB-KW GO:0046677, P:response to antibiotic, IEA:UniProtKB-KW GO:0006351, P:transcription, DNA-templated, IEA:UniProtKB-KW Phylogenomic databases eggNOG COG0745, - Enzyme and pathway databases BioCyc EFAE226185:GHI1-2255-MONOMER, - Family and domain databases InterPro IPR011006, CheY-like_superfamily IPR001867, Sig_transdc_resp-reg_C IPR001789, Sig_transdc_resp-reg_receiver IPR011991, WHTH_DNA-bd_dom Pfam PF00072, Response_reg, 1 PF00486, Trans_reg_C, 1 SMART SM00448, REC, 1 SM00862, Trans_reg_C, 1 PROSITE PS50110, RESPONSE_REGULATORY, 1
配列の特徴	Q47744 Enterococcus faecalis (strain ATCC 700802 / V583). MOD_RES 53 4-aspartylphosphate (By similarity).
注釈	Function Member of the two-component regulatory system VanS/VanR. Activates the transcription of vanH, vanA and vanX in response to vancomycin which results in vancomycin resistance Sequence similarities Contains 1 response regulatory domain
参考文献	Q47744 Enterococcus faecalis (strain ATCC 700802 / V583). 8631706 Regulation of VanB-type vancomycin resistance gene expression by the VanS(B)-VanR (B) two-component regulatory system in Enterococcus faecalis V583. (J Bacteriol. 1996)

関与する機能

機能名
Vancomycin resistance (via D-Ala-D-Lac precursor)

該当CDS