遺伝子 : Anthranilate 1,2-dioxygenase small subunit (ANTB)

遺伝子情報

ID	NRULE_0045
遺伝子ID	ANTB
作成日	2012/08/21
タンパク質名	Protein name Full Anthranilate 1,2-dioxygenase small subunit EC EC 1.14.12.1
遺伝子名	antB
遺伝子条件	TIGRFAMs; TIGR03231; hit=1
参照	Gene Ontology GO GO:0018618, F:anthranilate 1,2-dioxygenase (deaminating, decarboxylating) activity, IEA:EC GO:0016702, F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, IEA:UniProtKB-KW GO:0019439, P:aromatic compound catabolic process, IEA:UniProtKB-KW Enzyme and pathway databases UniPathway UPA01016, UER01026 Family and domain databases InterPro IPR017640, Anthranilate_1-2-diOase_ssu IPR000391, Rng_hydr_dOase-bsu Pfam PF00866, Ring_hydroxyl_B, 1 TIGRFAMs TIGR03231, Anthran_1_2_B, 1
配列の特徴	該当データなし
注釈	Function Component of anthranilate dioxygenase multicomponent enzyme system which catalyzes the incorporation of both atoms of molecular oxygen into anthranilate to form catechol Catalytic activity Anthranilate + NAD(P)H + O(2) = catechol + CO(2) + NAD(P)(+) + NH(3) Cofactor Binds 1 iron ion per subunit Binds 1 2Fe-2S cluster per subunit Pathway Aromatic compound metabolism; anthranilate degradation via hydroxylation; catechol from anthranilate: step 1/1 Subunit structure The anthranilate dioxygenase multicomponent enzyme system is composed of a two-subunit oxygenase component and an electron transfer component (ferredoxin and ferredoxin reductase) Sequence similarities Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family
参考文献	O85674 Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1). 9721284 Similarities between the antABC-encoded anthranilate dioxygenase and the benABC-encoded benzoate dioxygenase of Acinetobacter sp. strain ADP1. (J Bacteriol. 1998) 11114907 Characterization and evolution of anthranilate 1,2-dioxygenase from Acinetobacter sp. strain ADP1. (J Bacteriol. 2001) 14622009 Histidine ligand protonation and redox potential in the rieske dioxygenases: role of a conserved aspartate in anthranilate 1,2-dioxygenase. (Biochemistry. 2003) Q84BZ2 Burkholderia cepacia (Pseudomonas cepacia). 13129960 Characterization and regulation of the genes for a novel anthranilate 1,2-dioxygenase from Burkholderia cepacia DBO1. (J Bacteriol. 2003)

関与する機能

機能名
Anthranilate degradation (via hydroxylation)

該当CDS

学名	NBRC番号	CDS	タンパク質名
Acinetobacter radioresistens	102413	ACRAD_20_01470	anthranilate 1,2-dioxygenase small subunit
Shimwellia blattae	105725	EB105725_04_00060	3-phenylpropionate/cinnamic acid dioxygenase beta subunit