遺伝子 : Anthranilate 1,2-dioxygenase electron transfer component (ANTC)

遺伝子情報

ID	NRULE_0081
遺伝子ID	ANTC
作成日	2012/11/21
タンパク質名	Protein name Full Anthranilate 1,2-dioxygenase electron transfer component
遺伝子名	antC
遺伝子条件	PFAM; PF00970; hit=1ANDPFAM; PF00175; hit=1ANDPFAM; PF00111; hit=1ANDBLASTP; O85675; hit=1; score=850; pid=45
参照	Gene Ontology GO GO:0051537, F:2 iron, 2 sulfur cluster binding, IEA:UniProtKB-KW GO:0009055, F:electron carrier activity, IEA:InterPro GO:0008860, F:ferredoxin-NAD+ reductase activity, IEA:EC GO:0046872, F:metal ion binding, IEA:UniProtKB-KW GO:0019439, P:aromatic compound catabolic process, IEA:UniProtKB-KW Phylogenomic databases KO K11311, - Enzyme and pathway databases UniPathway UPA01016, UER01026 Family and domain databases InterPro IPR001041, 2Fe-2S_ferredoxin-type IPR006058, 2Fe2S_fd_BS IPR012675, Beta-grasp_dom IPR017927, Fd_Rdtase_FAD-bd IPR008333, OxRdtase_FAD-bd_dom IPR001433, OxRdtase_FAD/NAD-bd IPR001221, Phe_hydroxylase IPR017938, Riboflavin_synthase-like_b-brl Pfam PF00970, FAD_binding_6, 1 PF00111, Fer2, 1 PF00175, NAD_binding_1, 1 PRINTS PR00410, PHEHYDRXLASE PROSITE PS00197, 2FE2S_FER_1, 1 PS51085, 2FE2S_FER_2, 1 PS51384, FAD_FR, 1
配列の特徴	O85675 Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1). METAL 40 Iron-sulfur (2Fe-2S). METAL 45 Iron-sulfur (2Fe-2S). METAL 48 Iron-sulfur (2Fe-2S). METAL 80 Iron-sulfur (2Fe-2S).
注釈	Function Electron transfer component of anthranilate 1,2- dioxygenase system Catalytic activity Reduced ferredoxin + NAD(+) = oxidized ferredoxin + NADH Cofactor FAD Binds 1 2Fe-2S cluster per subunit Pathway Aromatic compound metabolism; anthranilate degradation via hydroxylation; catechol from anthranilate: step 1/1 Subunit structure Monomer. It is part of the anthranilate dioxygenase two component enzyme system. The other component is an oxygenase component consisting of large (AntA) and small (AntB) subunits Sequence similarities Belongs to the bacterial ring-hydroxylating dioxygenase ferredoxin reductase family Contains 1 2Fe-2S ferredoxin-type domain Contains 1 FAD-binding FR-type domain
参考文献	O85675 Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1). 9721284 Similarities between the antABC-encoded anthranilate dioxygenase and the benABC-encoded benzoate dioxygenase of Acinetobacter sp. strain ADP1. (J Bacteriol. 1998) 11114907 Characterization and evolution of anthranilate 1,2-dioxygenase from Acinetobacter sp. strain ADP1. (J Bacteriol. 2001)

関与する機能

機能名
Anthranilate degradation (via hydroxylation)

該当CDS

学名	NBRC番号	CDS	タンパク質名
Acinetobacter radioresistens	102413	ACRAD_20_01480	anthranilate 1,2-dioxygenase electron transfer component
Shimwellia blattae	105725	EB105725_04_00050	putative oxidoreductase