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Rule : NAD(P)H azoreductase (AZOB)

Rule Description

ID NRULE_0238
Rule name AZOB
Created 2013-08-26
Protein name
Protein name
Full
NAD(P)H azoreductase
EC
EC 1.7.-.-
Gene name Not assigned
Rule Trigger BLASTP; Q8KU07; hit=1; score=1000; pid=80
Cross Reference
Gene Ontology
GO
GO:0016491, F:oxidoreductase activity, IEA:UniProtKB-KW
Family and domain databases
InterPro
IPR016040, NAD(P)-bd_dom
IPR008030, NmrA
Pfam
PF05368, NmrA, 1
Feature
Q8KU07 Xenophilus azovorans.
NP_BIND2 - 19NAD(P) (Potential).
NP_BIND29 - 33NAD(P) (Potential).
General annotation
Function
Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Uses preferentially NADPH rather than NADH as an electron donor for its activity. The enzyme reductively cleaved Orange II and carboxy-Orange II, and can also reduce several sulfonated structural analogs, which carry a hydroxy group in the 2 position of the naphthol ring
Subunit structure
Monomer
Sequence similarities
Belongs to the NmrA-type oxidoreductase family. Azoreductase type 3 subfamily
Reference
Q8KU07 Xenophilus azovorans.
12147495
Molecular cloning and characterization of the gene coding for the aerobic azoreductase from Xenophilus azovorans KF46F. (Appl Environ Microbiol. 2002)



Related Function

Function name
Aromatic azo compounds degradation

CDS

Not assigned