Rule : Periplasmic AppA protein (APPA)

Rule Description

ID	NRULE_0259
Rule name	APPA
Created	2014-02-06
Protein name	Protein name Full Periplasmic AppA protein
Gene name	appA
Rule Trigger	BLASTP; P07102; hit=1; score=600; pid=35
Cross Reference	Gene Ontology GO GO:0042597, C:periplasmic space, IDA:EcoCyc GO:0008707, F:4-phytase activity, IDA:EcoCyc GO:0003993, F:acid phosphatase activity, IDA:EcoCyc GO:0071454, P:cellular response to anoxia, IDA:EcoCyc GO:0016036, P:cellular response to phosphate starvation, IDA:EcoCyc Phylogenomic databases KO K01093, - Enzyme and pathway databases BioCyc MetaCyc:APPA-MONOMER, - Family and domain databases InterPro IPR000560, His_Pase_superF_clade-2
Feature	Not assigned
General annotation	Not assigned
Reference	P07102 Escherichia coli (strain K12). 2168385 The complete nucleotide sequence of the Escherichia coli gene appA reveals significant homology between pH 2.5 acid phosphatase and glucose-1-phosphatase. (J Bacteriol. 1990) 10696472 Characterization and overproduction of the Escherichia coli appA encoded bifunctional enzyme that exhibits both phytase and acid phosphatase activities. (Can J Microbiol. 2000)

Function name
Phytic acid hydrolysis


Scientific name	NBRC No.	CDS	Product name
Edwardsiella tarda	105688	ET1_03_00060	acid phosphatase/4-phytase AppA
Escherichia coli	3972	EcolC_2616	histidine acid phosphatase
Escherichia coli	13500	WFL_05315	phosphoanhydride phosphorylase
Escherichia coli	12713	Y75_0955	phosphoanhydride phosphorylase
Escherichia fergusonii	102419	EFER_3043	Periplasmic appA protein precursor [Includes: Phosphoanhydride phosphohydrolase (pH 2.5 acid phosphatase) (AP); 4-phytase]
Yersinia bercovieri	105717	yberc0001_18000	Histidine acid phosphatase
Yersinia rohdei	105715	yrohd0001_34970	Histidine acid phosphatase