Rule : D-alanyl-D-alanine dipeptidase (VANX)

Rule Description

ID	NRULE_0267
Rule name	VANX
Created	2014-06-19
Protein name	Protein name Full D-alanyl-D-alanine dipeptidase Short D-Ala-D-Ala dipeptidase D,D-dipeptidase EC EC 3.4.13.22
Gene name	vanX
Rule Trigger	BLASTP; Q9ZI81; hit=1; score=600; pid=60
Cross Reference	Gene Ontology GO GO:0005618, C:cell wall, IEA:InterPro GO:0016805, F:dipeptidase activity, IEA:InterPro GO:0008237, F:metallopeptidase activity, IEA:InterPro Family and domain databases InterPro IPR009045, Hedgehog_sig/DD-Pept_Zn-bd_dom IPR000755, Peptidase_M15D Pfam PF01427, Peptidase_M15, 1
Feature	Not assigned
General annotation	Not assigned
Reference	Q9ZI81 Streptomyces toyocaensis. 9751644 Homologs of the vancomycin resistance D-Ala-D-Ala dipeptidase VanX in Streptomyces toyocaensis, Escherichia coli and Synechocystis: attributes of catalytic efficiency, stereoselectivity and regulation with implications for function. (Chem Biol. 1998)

Function name
Vancomycin resistance (via D-Ala-D-Lac precursor)


Scientific name	NBRC No.	CDS	Product name
Amycolatopsis azurea	14573	C791_3574	Vancomycin B-type resistance protein VanX
Amycolatopsis mediterranei	13415	RAM_42560	D-alanyl-D-alanine dipeptidase
Catenulispora acidiphila	102108	Caci_5792	peptidase M15D vanX D-ala-D-ala dipeptidase
Conexibacter woesei	100937	Cwoe_1415	D-Ala-D-Ala dipeptidase
Kribbella flavida	14399	Kfla_3621	D-Ala-D-Ala dipeptidase
Saccharothrix espanaensis	15066	BN6_49750	D-alanyl-D-alanine dipeptidase
Stackebrandtia nassauensis	102104	Snas_5357	D-Ala-D-Ala dipeptidase
Streptomyces sviceus	13980	SSEG_10122	D-alanine dipeptidase
Tsukamurella paurometabola	16120	Tpau_0522	D-Ala-D-Ala dipeptidase