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Rule : D-alanyl-D-alanine dipeptidase (VANX)

Rule Description

ID NRULE_0267
Rule name VANX
Created 2014-06-19
Protein name
Protein name
Full
D-alanyl-D-alanine dipeptidase
Short
D-Ala-D-Ala dipeptidase
D,D-dipeptidase
EC
EC 3.4.13.22
Gene name vanX
Rule Trigger BLASTP; Q9ZI81; hit=1; score=600; pid=60
Cross Reference
Gene Ontology
GO
GO:0005618, C:cell wall, IEA:InterPro
GO:0016805, F:dipeptidase activity, IEA:InterPro
GO:0008237, F:metallopeptidase activity, IEA:InterPro
Family and domain databases
InterPro
IPR009045, Hedgehog_sig/DD-Pept_Zn-bd_dom
IPR000755, Peptidase_M15D
Pfam
PF01427, Peptidase_M15, 1
Feature Not assigned
General annotation Not assigned
Reference
Q9ZI81 Streptomyces toyocaensis.
9751644
Homologs of the vancomycin resistance D-Ala-D-Ala dipeptidase VanX in Streptomyces toyocaensis, Escherichia coli and Synechocystis: attributes of catalytic efficiency, stereoselectivity and regulation with implications for function. (Chem Biol. 1998)



Related Function

Function name
Vancomycin resistance (via D-Ala-D-Lac precursor)

CDS

Data Download
Scientific name NBRC No. CDS Product name
Amycolatopsis azurea14573C791_3574Vancomycin B-type resistance protein VanX
Amycolatopsis mediterranei13415RAM_42560D-alanyl-D-alanine dipeptidase
Catenulispora acidiphila102108Caci_5792peptidase M15D vanX D-ala-D-ala dipeptidase
Conexibacter woesei100937Cwoe_1415D-Ala-D-Ala dipeptidase
Kribbella flavida14399Kfla_3621D-Ala-D-Ala dipeptidase
Saccharothrix espanaensis15066BN6_49750D-alanyl-D-alanine dipeptidase
Stackebrandtia nassauensis102104Snas_5357D-Ala-D-Ala dipeptidase
Streptomyces sviceus13980SSEG_10122D-alanine dipeptidase
Tsukamurella paurometabola16120Tpau_0522D-Ala-D-Ala dipeptidase