遺伝子 : Two-component system response regulator VanR (VANR)

遺伝子情報

ID	NRULE_0284
遺伝子ID	VANR
作成日	2014/07/09
タンパク質名	Protein name Full Two-component system response regulator VanR
遺伝子名	vanR
遺伝子条件	BLASTP; Q8CJW1; hit=1; score=900; pid=75
参照	Gene Ontology GO GO:0003677, F:DNA binding, IEA:InterPro GO:0000156, F:phosphorelay response regulator activity, IEA:InterPro GO:0006355, P:regulation of transcription, DNA-templated, IEA:UniProtKB-KW GO:0006351, P:transcription, DNA-templated, IEA:UniProtKB-KW Family and domain databases InterPro IPR011006, CheY-like_superfamily IPR001867, Sig_transdc_resp-reg_C IPR001789, Sig_transdc_resp-reg_receiver IPR011991, WHTH_DNA-bd_dom Pfam PF00072, Response_reg, 1 PF00486, Trans_reg_C, 1 SMART SM00448, REC, 1 SM00862, Trans_reg_C, 1 PROSITE PS50110, RESPONSE_REGULATORY, 1
配列の特徴	該当データなし
注釈	Sequence similarities Contains response regulatory domain Note Amycolatopsis balhimycina vanR gene (Q799B5) is contained in this rule. But it has been demonstrated that this gene was not involved in glycopeptide resistance or in the expression of the vanHAX glycopeptide resistance genes (PMID 21690280)
参考文献	Q8CJW1 Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145). 15130128 Characterization of an inducible vancomycin resistance system in Streptomyces coelicolor reveals a novel gene (vanK) required for drug resistance. (Mol Microbiol. 2004) 16420361 The vancomycin resistance VanRS two-component signal transduction system of Streptomyces coelicolor. (Mol Microbiol. 2006)

関与する機能

機能名
Vancomycin resistance (via D-Ala-D-Lac precursor)

該当CDS

学名	NBRC番号	CDS	タンパク質名
Actinomadura atramentaria	14695	G339_07810	transcriptional regulator
Actinoplanes missouriensis	102363	AMIS_51740	putative two-component system response regulator
Amycolatopsis mediterranei	13415	RAM_42550	two-component system response regulator
Catenulispora acidiphila	102108	Caci_5788	two component transcriptional regulator, winged helix family
Conexibacter woesei	100937	Cwoe_1412	two component transcriptional regulator, winged helix family
Kribbella flavida	14399	Kfla_3625	two component transcriptional regulator, winged helix family
Microlunatus phosphovorus	101784	MLP_00360	two-component system response regulator
Saccharothrix espanaensis	15066	BN6_49710	Transcriptional regulator, CutR family
Stackebrandtia nassauensis	102104	Snas_6028	two component transcriptional regulator, winged helix family
Streptomyces pristinaespiralis	13074	SSDG_04292	two-component system response regulator
Streptomyces sviceus	13980	SSEG_08352	two component transcriptional regulator
Streptomyces venezuelae	13096	SVEN_6832	Vancomycin response regulator VanR
Streptosporangium roseum	3776	Sros_4756	response regulator receiver protein
Tsukamurella paurometabola	16120	Tpau_0520	two component transcriptional regulator, winged helix family
Xylanimonas cellulosilytica	107835	Xcel_1424	two component transcriptional regulator, winged helix family