| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
A4D940_9NOSO (A4D940) |
|
|
0.0 |
1008 |
100% |
|
- Product
- CrpH
- Gene
- crpH
- Organism
- Nostoc sp. ATCC 53789
|
1uniprot[Pubmed] 17240975 Biosynthetic characterization and chemoenzymatic assembly of the cryptophycins. Potent anticancer agents from cyanobionts.(ACS Chem. Biol.) [2006] |
|
2
|
Q2SW45_BURTA (Q2SW45) |
|
|
1e-143 |
513 |
51% |
|
- Product
- FAD binding domain protein
- Gene
- BTH_I2333
- Organism
- Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301)
|
1uniprot[Pubmed] 16336651 Bacterial genome adaptation to niches: divergence of the potential virulence genes in three Burkholderia species of different survival strategies.(BMC Genomics) [2005] |
|
7
|
Q63UI3_BURPS (Q63UI3) |
|
|
1e-140 |
503 |
52% |
|
- Product
- Putative hydroxylase
- Gene
- BPSL1617
- Organism
- Burkholderia pseudomallei
Pseudomonas pseudomallei
|
1uniprot[Pubmed] 15377794 Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei.(Proc. Natl. Acad. Sci. U.S.A.) [2004] |
|
8
|
Q62KP9_BURMA (Q62KP9) |
|
|
1e-140 |
503 |
52% |
|
- Product
- FAD binding domain protein
- Gene
- BMA1005
- Organism
- Burkholderia mallei
Pseudomonas mallei
|
1uniprot[Pubmed] 15377793 Structural flexibility in the Burkholderia mallei genome.(Proc. Natl. Acad. Sci. U.S.A.) [2004] |
|
24
|
Q0RGW0_FRAAA (Q0RGW0) |
|
|
1e-133 |
481 |
52% |
|
- Product
- Putative halogenase
- Gene
- FRAAL4634
- Organism
- Frankia alni (strain ACN14a)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
25
|
D2AY55_STRRD (D2AY55) |
|
|
1e-130 |
468 |
50% |
|
- Product
- Putative tryptophan halogenase
- Gene
- Sros_4161
- Organism
- Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
|
1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010] |
|
26
|
A7DWL5_STRTE (A7DWL5) |
|
|
1e-129 |
465 |
49% |
|
- Product
- Putative non-heme halogenase
- Gene
- llpH
- Organism
- Streptomyces tendae
|
1uniprot Isolation of the lysolipin gene cluster of Streptomyces tendae Tu 4042.(Gene) [2010] |
|
28
|
THAL_CHOCO (Q0VZ69) |
|
|
1e-124 |
449 |
48% |
|
- Product
- Tryptophan 2-halogenase
- Gene
- cmdE
- Organism
- Chondromyces crocatus
|
1uniprot[Pubmed] 16793524 Molecular and biochemical studies of chondramide formation-highly cytotoxic natural products from Chondromyces crocatus Cm c5.(Chem. Biol.) [2006] |
|
30
|
C7PXC2_CATAD (C7PXC2) |
|
|
1e-117 |
426 |
47% |
|
- Product
- Tryptophan halogenase
- Gene
- Caci_0530
- Organism
- Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
|
1uniprot Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009] |
|
32
|
C7PZI2_CATAD (C7PZI2) |
|
|
1e-101 |
372 |
41% |
|
- Product
- Tryptophan halogenase
- Gene
- Caci_2724
- Organism
- Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
|
1uniprot Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009] |
|
33
|
F2LCF5_BURGA (F2LCF5) |
|
|
2e-99 |
367 |
41% |
|
- Product
- Putative halogenase
- Gene
- bgla_1g15510
- Organism
- Burkholderia gladioli BSR3
|
1uniprot[Pubmed] 21478339 Complete Genome Sequence of Burkholderia gladioli BSR3.(J. Bacteriol.) [2011] |
|
34
|
F2LCF3_BURGA (F2LCF3) |
|
|
2e-97 |
361 |
41% |
|
- Product
- Putative halogenase
- Gene
- bgla_1g15490
- Organism
- Burkholderia gladioli BSR3
|
1uniprot[Pubmed] 21478339 Complete Genome Sequence of Burkholderia gladioli BSR3.(J. Bacteriol.) [2011] |
|
35
|
Q5YXW4_NOCFA (Q5YXW4) |
|
|
2e-90 |
338 |
41% |
|
- Product
- Putative halogenase
- Gene
- NFA_21310
- Organism
- Nocardia farcinica
|
1uniprot[Pubmed] 15466710 The complete genomic sequence of Nocardia farcinica IFM 10152.(Proc. Natl. Acad. Sci. U.S.A.) [2004] |
|
36
|
E9LIP1_9ACTO (E9LIP1) |
|
|
2e-90 |
337 |
39% |
|
- Product
- Putative tryptophan halogenase
- Gene
- tiaM
- Organism
- Dactylosporangium aurantiacum subsp. hamdenensis
|
1uniprot[Pubmed] 21186805 Characterization of tiacumicin B biosynthetic gene cluster affording diversified tiacumicin analogues and revealing a tailoring dihalogenase.(J. Am. Chem. Soc.) [2011] |
|
39
|
B8YGP8_9ACTO (B8YGP8) |
|
|
9e-75 |
286 |
60% |
|
- Product
- Halogenase
- Gene
-
- Organism
- Actinocorallia aurantiaca
|
1uniprot[Pubmed] 19447951 Detection, distribution, and organohalogen compound discovery implications of the reduced flavin adenine dinucleotide-dependent halogenase gene in major filamentous actinomycete taxonomic groups.(Appl. Environ. Microbiol.) [2009] |
|
40
|
P96557_AMYOR (P96557) |
|
|
1e-73 |
281 |
37% |
|
- Product
- PCZA361.26
- Gene
-
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 9545426 [Medline] 98212597 Sequencing and analysis of genes involved in the biosynthesis of a vancomycin group antibiotic.(Chem. Biol.) [1998] |
|
44
|
C8VB32_EMENI (C8VB32) |
|
|
4e-72 |
277 |
41% |
|
- Product
- Putative uncharacterized protein
- Gene
- ANIA_10884
- Organism
- Aspergillus nidulans FGSC A4
|
1uniprot The 2008 update of the Aspergillus nidulans genome annotation: A community effort.(Fungal Genet. Biol.) [2009] |
|
45
|
B7T185_9BACT (B7T185) |
|
|
4e-72 |
277 |
37% |
|
- Product
- Veg13
- Gene
- veg13
- Organism
- uncultured soil bacterium
|
1uniprot[Pubmed] 18987322 Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary.(Proc. Natl. Acad. Sci. U.S.A.) [2008] |
|
46
|
Q5AXB1_EMENI (Q5AXB1) |
|
|
4e-72 |
276 |
41% |
|
- Product
- Putative uncharacterized protein
- Gene
- AN7069.2
- Organism
- Emericella nidulans
Aspergillus nidulans
|
1uniprot[Pubmed] 16372000 Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae.(Nature) [2005] |
|
47
|
B8YGQ0_9ACTO (B8YGQ0) |
|
|
5e-72 |
276 |
39% |
|
- Product
- Halogenase
- Gene
-
- Organism
- Planobispora longispora
|
1uniprot[Pubmed] 19447951 Detection, distribution, and organohalogen compound discovery implications of the reduced flavin adenine dinucleotide-dependent halogenase gene in major filamentous actinomycete taxonomic groups.(Appl. Environ. Microbiol.) [2009] |
|
50
|
Q2UPC7_ASPOR (Q2UPC7) |
|
|
4e-71 |
273 |
37% |
|
- Product
- Predicted protein
- Gene
- AO090001000024
- Organism
- Aspergillus oryzae (strain ATCC 42149 / RIB 40)
|
1uniprot[Pubmed] 16372010 Genome sequencing and analysis of Aspergillus oryzae.(Nature) [2005] |
|
53
|
Q93N83_STRLA (Q93N83) |
|
|
5e-71 |
273 |
35% |
|
- Product
- Non-heme halogenase
- Gene
-
- Organism
- Streptomyces lavendulae
|
1uniprot[Pubmed] 11447274 [Medline] 21353013 Molecular cloning and sequence analysis of the complestatin biosynthetic gene cluster.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
54
|
C7ZM13_NECH7 (C7ZM13) |
|
|
5e-71 |
273 |
38% |
|
- Product
- Putative uncharacterized protein
- Gene
- NECHADRAFT_37333
- Organism
- Nectria haematococca (strain 77-13-4 / FGSC 9596 / MPVI)
Fusarium solani subsp. pisi
|
1uniprot[Pubmed] 19714214 The genome of Nectria haematococca: contribution of supernumerary chromosomes to gene expansion.(PLoS Genet.) [2009] |
|
57
|
B8YGP3_9ACTO (B8YGP3) |
|
|
1e-70 |
272 |
35% |
|
- Product
- Halogenase
- Gene
-
- Organism
- Catenuloplanes nepalensis
|
1uniprot[Pubmed] 19447951 Detection, distribution, and organohalogen compound discovery implications of the reduced flavin adenine dinucleotide-dependent halogenase gene in major filamentous actinomycete taxonomic groups.(Appl. Environ. Microbiol.) [2009] |
|
62
|
O87676_9PSEU (O87676) |
|
|
3e-70 |
270 |
38% |
|
- Product
- Halogenase
- Gene
- bhaA
- Organism
- Amycolatopsis balhimycina
|
1uniprot[Pubmed] 10390204 [Medline] 99318579 Identification and analysis of the balhimycin biosynthetic gene cluster and its use for manipulating glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908.(Antimicrob. Agents Chemother.) [1999] | 2uniprot[Pubmed] 11932455 [Medline] 21930292 Nonribosomal biosynthesis of vancomycin-type antibiotics: a heptapeptide backbone and eight peptide synthetase modules.(Microbiology) [2002] | 3uniprot[Pubmed] 11495926 [Medline] 21486455 A polyketide synthase in glycopeptide biosynthesis: the biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine.(J. Biol. Chem.) [2001] | 4uniprot[Pubmed] 12404385 The biosynthesis of vancomycin-type glycopeptide antibiotics - the order of cyclization steps.(Angew. Chem. Int. Ed. Engl.) [2001] | 5uniprot[Pubmed] 11880037 [Medline] 21869276 Glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908: function of a halogenase and a haloperoxidase/perhydrolase.(Chem. Biol.) [2002] | 6uniprot Precursor-directed biosynthesis for the generation of novel glycopetides.(Ernst Schering Res. Found. Workshop) [2005] | [pubmed all]
|
64
|
Q6ZZI5_ACTTI (Q6ZZI5) |
|
|
4e-70 |
270 |
37% |
|
- Product
- Halogenase
- Gene
-
- Organism
- Actinoplanes teichomyceticus
|
1uniprot[Pubmed] 15113000 Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase.(Chem. Biol.) [2004] |
|
65
|
A8P2G9_COPC7 (A8P2G9) |
|
|
4e-70 |
270 |
42% |
|
- Product
- Putative uncharacterized protein
- Gene
- CC1G_04762
- Organism
- Coprinopsis cinerea (strain Okayama-7 / 130 / FGSC 9003)
Inky cap fungus Hormographiella aspergillata
|
1uniprot[Pubmed] 20547848 Insights into evolution of multicellular fungi from the assembled chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus).(Proc. Natl. Acad. Sci. U.S.A.) [2010] |
|
67
|
Q8GMI1_STRGL (Q8GMI1) |
|
|
6e-70 |
270 |
37% |
|
- Product
- Alkylhalidase
- Gene
-
- Organism
- Streptomyces globisporus
|
1uniprot[Pubmed] 12183628 [Medline] 22171413 Biosynthesis of the enediyne antitumor antibiotic C-1027.(Science) [2002] |
|
68
|
Q8KLM0_STRTO (Q8KLM0) |
|
|
6e-70 |
270 |
39% |
|
- Product
- StaI
- Gene
-
- Organism
- Streptomyces toyocaensis
|
1uniprot[Pubmed] 9177243 [Medline] 97322398 D-Ala-D-Ala ligases from glycopeptide antibiotic-producing organisms are highly homologous to the enterococcal vancomycin-resistance ligases VanA and VanB.(Proc. Natl. Acad. Sci. U.S.A.) [1997] | 2uniprot[Pubmed] 12060705 [Medline] 22080153 Assembling the glycopeptide antibiotic scaffold: the biosynthesis of A47934 from Streptomyces toyocaensis NRRL15009.(Proc. Natl. Acad. Sci. U.S.A.) [2002] | [pubmed all]
|
69
|
Q70AY7_ACTTI (Q70AY7) |
|
|
6e-70 |
270 |
37% |
|
- Product
- Halogenase
- Gene
- tcp21
- Organism
- Actinoplanes teichomyceticus
|
1uniprot[Pubmed] 14702401 Organization of the teicoplanin gene cluster in Actinoplanes teichomyceticus.(Microbiology) [2004] |
|
72
|
B7T1E1_9BACT (B7T1E1) |
|
|
3e-69 |
267 |
37% |
|
- Product
- Teg16
- Gene
- teg16
- Organism
- uncultured soil bacterium
|
1uniprot[Pubmed] 18987322 Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary.(Proc. Natl. Acad. Sci. U.S.A.) [2008] |
|
73
|
B8YGQ3_9ACTO (B8YGQ3) |
|
|
5e-69 |
266 |
37% |
|
- Product
- Halogenase
- Gene
-
- Organism
- Catenulispora yoronensis
|
1uniprot[Pubmed] 19447951 Detection, distribution, and organohalogen compound discovery implications of the reduced flavin adenine dinucleotide-dependent halogenase gene in major filamentous actinomycete taxonomic groups.(Appl. Environ. Microbiol.) [2009] |
|
74
|
D6RQS1_COPC7 (D6RQS1) |
|
|
1e-68 |
265 |
39% |
|
- Product
- Putative uncharacterized protein
- Gene
- CC1G_15391
- Organism
- Coprinopsis cinerea (strain Okayama-7 / 130 / FGSC 9003)
Inky cap fungus Hormographiella aspergillata
|
1uniprot[Pubmed] 20547848 Insights into evolution of multicellular fungi from the assembled chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus).(Proc. Natl. Acad. Sci. U.S.A.) [2010] |
|
75
|
D4B3N8_ARTBC (D4B3N8) |
|
|
1e-68 |
265 |
38% |
|
- Product
- Putative uncharacterized protein
- Gene
- ARB_03077
- Organism
- Arthroderma benhamiae (strain CBS 112371)
Trichophyton mentagrophytes
|
1uniprot[Pubmed] 21247460 Comparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi.(Genome Biol.) [2011] |
|
77
|
C5H881_9PEZI (C5H881) |
|
|
2e-68 |
264 |
39% |
|
- Product
- RadH flavin-dependent halogenase
- Gene
-
- Organism
- Chaetomium chiversii
|
1uniprot[Pubmed] 19101477 Functional characterization of the biosynthesis of radicicol, an Hsp90 inhibitor resorcylic acid lactone from Chaetomium chiversii.(Chem. Biol.) [2008] |
|
78
|
E9L1L8_9ZZZZ (E9L1L8) |
|
|
2e-68 |
264 |
37% |
|
- Product
- Putative uncharacterized protein
- Gene
- CA878-19
- Organism
- uncultured organism CA878
|
1uniprot[Pubmed] 20945895 Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products.(J. Am. Chem. Soc.) [2010] |
|
79
|
E1B2D7_VERCH (E1B2D7) |
|
|
4e-68 |
263 |
39% |
|
- Product
- Rdc2
- Gene
- rdc2
- Organism
- Verticillium chlamydosporium
|
1uniprot A Novel Fungal Flavin-Dependent Halogenase for Natural Product Biosynthesis.(Chembiochem) [2010] |
|
81
|
D8Q9Q3_SCHCM (D8Q9Q3) |
|
|
1e-67 |
262 |
40% |
|
- Product
- Putative uncharacterized protein
- Gene
- SCHCODRAFT_58114
- Organism
- Schizophyllum commune (strain H4-8 / FGSC 9210)
Split gill fungus
|
1uniprot[Pubmed] 20622885 Genome sequence of the model mushroom Schizophyllum commune.(Nat. Biotechnol.) [2010] |
|
83
|
B3FWT7_VERCH (B3FWT7) |
|
|
1e-67 |
262 |
39% |
|
- Product
- Non-heme halogenase
- Gene
- Rdc2
- Organism
- Verticillium chlamydosporium
|
1uniprot[Pubmed] 18567690 Genes for the biosynthesis of the fungal polyketides hypothemycin from Hypomyces subiculosus and radicicol from Pochonia chlamydosporia.(Appl. Environ. Microbiol.) [2008] |
|
85
|
D8QFY3_SCHCM (D8QFY3) |
|
|
5e-67 |
259 |
39% |
|
- Product
- Putative uncharacterized protein
- Gene
- SCHCODRAFT_28531
- Organism
- Schizophyllum commune (strain H4-8 / FGSC 9210)
Split gill fungus
|
1uniprot[Pubmed] 20622885 Genome sequence of the model mushroom Schizophyllum commune.(Nat. Biotechnol.) [2010] |
|
86
|
D7PI14_9EURO (D7PI14) |
|
|
6e-67 |
259 |
38% |
|
- Product
- GsfI
- Gene
-
- Organism
- Penicillium aethiopicum
|
1uniprot[Pubmed] 20534346 Identification of the viridicatumtoxin and griseofulvin gene clusters from Penicillium aethiopicum.(Chem. Biol.) [2010] |
|
88
|
B0BLN9_9ACTO (B0BLN9) |
|
|
1e-66 |
259 |
38% |
|
- Product
- Halogenase
- Gene
- mdpC
- Organism
- Actinomadura madurae
|
1uniprot[Pubmed] 14528002 [Medline] 22922109 Rapid PCR amplification of minimal enediyne polyketide synthase cassettes leads to a predictive familial classification model.(Proc. Natl. Acad. Sci. U.S.A.) [2003] | 2uniprot[Pubmed] 17918933 Characterization of the maduropeptin biosynthetic gene cluster from Actinomadura madurae ATCC 39144 supporting a unifying paradigm for enediyne biosynthesis.(J. Am. Chem. Soc.) [2007] | [pubmed all]
|
90
|
Q7WZ81_9ACTO (Q7WZ81) |
|
|
3e-66 |
257 |
38% |
|
- Product
- Halogenase
- Gene
- dbv10
- Organism
- Nonomuraea sp. ATCC 39727
|
1uniprot[Pubmed] 12837387 [Medline] 22721464 The gene cluster for the biosynthesis of the glycopeptide antibiotic A40926 by nonomuraea species.(Chem. Biol.) [2003] |
|
91
|
D8PSG8_SCHCM (D8PSG8) |
|
|
6e-66 |
256 |
36% |
|
- Product
- Putative uncharacterized protein
- Gene
- SCHCODRAFT_46918
- Organism
- Schizophyllum commune (strain H4-8 / FGSC 9210)
Split gill fungus
|
1uniprot[Pubmed] 20622885 Genome sequence of the model mushroom Schizophyllum commune.(Nat. Biotechnol.) [2010] |
|
93
|
F0XE00_GROCL (F0XE00) |
|
|
5e-65 |
253 |
41% |
|
- Product
- Flavin-dependent halogenase O-methyltransferase bifunctional protein
- Gene
- CMQ_1182
- Organism
- Grosmannia clavigera (strain kw1407 / UAMH 11150)
Blue stain fungus Graphiocladiella clavigera
|
1uniprot[Pubmed] 21262841 Genome and transcriptome analyses of the mountain pine beetle-fungal symbiont Grosmannia clavigera, a lodgepole pine pathogen.(Proc. Natl. Acad. Sci. U.S.A.) [2011] |
|
94
|
A8P2H0_COPC7 (A8P2H0) |
|
|
6e-65 |
253 |
34% |
|
- Product
- Putative uncharacterized protein
- Gene
- CC1G_04763
- Organism
- Coprinopsis cinerea (strain Okayama-7 / 130 / FGSC 9003)
Inky cap fungus Hormographiella aspergillata
|
1uniprot[Pubmed] 20547848 Insights into evolution of multicellular fungi from the assembled chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus).(Proc. Natl. Acad. Sci. U.S.A.) [2010] |
|
95
|
B9ZUJ5_CHOCO (B9ZUJ5) |
|
|
8e-65 |
253 |
36% |
|
- Product
- Halogenase
- Gene
- cndH
- Organism
- Chondromyces crocatus
|
1uniprot Novel chemistry in the biosynthesis of the antibiotic chondrochlorens.(Chem. Biol.) [2009] |
|
98
|
D7C2E3_STRBB (D7C2E3) |
|
|
8e-64 |
249 |
35% |
|
- Product
- Tryptophan halogenase
- Gene
- SBI_00676
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
99
|
C5H890_9PEZI (C5H890) |
|
|
9e-64 |
249 |
36% |
|
- Product
- Putative flavin-dependent halogenase/O-methyltransferase bifunctional protein
- Gene
-
- Organism
- Chaetomium chiversii
|
1uniprot[Pubmed] 19101477 Functional characterization of the biosynthesis of radicicol, an Hsp90 inhibitor resorcylic acid lactone from Chaetomium chiversii.(Chem. Biol.) [2008] |
|
100
|
C7ZIB2_NECH7 (C7ZIB2) |
|
|
1e-63 |
249 |
37% |
|
- Product
- Putative uncharacterized protein
- Gene
- NECHADRAFT_52832
- Organism
- Nectria haematococca (strain 77-13-4 / FGSC 9596 / MPVI)
Fusarium solani subsp. pisi
|
1uniprot[Pubmed] 19714214 The genome of Nectria haematococca: contribution of supernumerary chromosomes to gene expansion.(PLoS Genet.) [2009] |
|