| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
Q9L4X8_9ACTO (Q9L4X8) |
|
|
7e-75 |
283 |
100% |
|
- Product
- ElmJ
Third ring cyclase
- Gene
- elmJ
- Organism
- Streptomyces olivaceus
|
1uniprot[Pubmed] 11325225 [Medline] 21225632 Cloning, sequencing, and heterologous expression of the elmGHIJ genes involved in the biosynthesis of the polyketide antibiotic elloramycin from Streptomyces olivaceus Tu2353.(J. Nat. Prod.) [2001] | 2uniprot[Pubmed] 18310024 Biosynthesis of elloramycin in Streptomyces olivaceus requires glycosylation by enzymes encoded outside the aglycon cluster.(Microbiology) [2008] | [pubmed all]
|
2
|
TCMJ_STRGA (P16558) |
|
|
3e-41 |
171 |
67% |
|
- Product
- Tetracenomycin polyketide synthesis protein tcmJ
- Gene
- tcmJ
- Organism
- Streptomyces glaucescens
|
1uniprot[Pubmed] 2684656 [Medline] 90060035 Analysis of the nucleotide sequence of the Streptomyces glaucescens tcmI genes provides key information about the enzymology of polyketide antibiotic biosynthesis.(EMBO J.) [1989] |
|
4
|
Q0RHJ6_FRAAA (Q0RHJ6) |
|
|
2e-32 |
142 |
54% |
|
- Product
- Polyketide synthase
- Gene
- FRAAL4388
- Organism
- Frankia alni (strain ACN14a)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
5
|
Q2MGD2_STRGR (Q2MGD2) |
|
|
6e-32 |
140 |
51% |
|
- Product
- Putative polyketide cyclase
- Gene
-
- Organism
- Streptomyces griseus
|
1uniprot[Pubmed] 16305230 Cloning, sequencing, analysis, and heterologous expression of the fredericamycin biosynthetic gene cluster from Streptomyces griseus.(J. Am. Chem. Soc.) [2005] |
|
8
|
WH16_STRCO (P23157) |
|
|
1e-31 |
139 |
54% |
|
- Product
- 16.7 kDa protein in whiE locus
WhiE ORF II
- Gene
- SCO5319
SC6G9.14
- Organism
- Streptomyces coelicolor
|
1uniprot[Pubmed] 2077356 [Medline] 91171868 Spore colour in Streptomyces coelicolor A3(2) involves the developmentally regulated synthesis of a compound biosynthetically related to polyketide antibiotics.(Mol. Microbiol.) [1990] | 2uniprot[Pubmed] 12000953 [Medline] 21996410 Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002] | [pubmed all]
|
9
|
SCHB_STRHA (Q05362) |
|
|
1e-31 |
139 |
57% |
|
- Product
- Protein schB
- Gene
- schB
- Organism
- Streptomyces halstedii
|
1uniprot[Pubmed] 8344517 [Medline] 93345807 Hybridization and DNA sequence analyses suggest an early evolutionary divergence of related biosynthetic gene sets encoding polyketide antibiotics and spore pigments in Streptomyces spp.(Gene) [1993] |
|
11
|
A8L2X7_FRASN (A8L2X7) |
|
|
3e-31 |
138 |
53% |
|
- Product
- Cupin 2 conserved barrel domain protein
- Gene
- Franean1_2392
- Organism
- Frankia sp. (strain EAN1pec)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
13
|
F4FBT8_VERMA (F4FBT8) |
|
|
5e-31 |
137 |
50% |
|
- Product
- Putative uncharacterized protein
- Gene
- VAB18032_18180
- Organism
- Verrucosispora maris (strain AB-18-032)
|
1uniprot[Pubmed] 21551311 Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011] |
|
14
|
CURC_STRCN (Q02586) |
|
|
8e-31 |
137 |
52% |
|
- Product
- Polyketide synthase CurC
- Gene
- curC
- Organism
- Streptomyces cyaneus
Streptomyces curacoi
|
1uniprot[Pubmed] 1644304 [Medline] 92354925 Analysis of a polyketide synthesis-encoding gene cluster of Streptomyces curacoi.(Gene) [1992] |
|
15
|
B0LJ13_9ACTO (B0LJ13) |
|
|
1e-30 |
136 |
49% |
|
- Product
- Lct30
- Gene
- lct30
- Organism
- Streptomyces rishiriensis
|
1uniprot[Pubmed] 18070976 Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit.(Antimicrob. Agents Chemother.) [2008] |
|
17
|
D8I4M2_AMYMU (D8I4M2) |
|
|
1e-30 |
135 |
52% |
|
- Product
- Cupin 2 domain-containing protein
- Gene
- AMED_5436
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
18
|
E4NJ50_KITSK (E4NJ50) |
|
|
2e-30 |
135 |
53% |
|
- Product
- Putative WhiE II homolog
- Gene
- sppH
KSE_72430
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
20
|
B0LJ47_9ACTO (B0LJ47) |
|
|
3e-30 |
135 |
50% |
|
- Product
- Lcz30
- Gene
- lcz30
- Organism
- Streptomyces sanglieri
|
1uniprot[Pubmed] 18070976 Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit.(Antimicrob. Agents Chemother.) [2008] |
|
22
|
Q2J932_FRASC (Q2J932) |
|
|
5e-30 |
134 |
53% |
|
- Product
- Cupin 2
- Gene
- Francci3_2852
- Organism
- Frankia sp. (strain CcI3)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
23
|
Q93HM3_STRAW (Q93HM3) |
|
|
8e-30 |
133 |
51% |
|
- Product
- Putative WhiE II homolog
WhiE II homolog
- Gene
- sppH
SAV2837 SAV_2837
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
24
|
D7C2K1_STRBB (D7C2K1) |
|
|
8e-30 |
133 |
52% |
|
- Product
- WhiE II-like protein
- Gene
- sppH
SBI_02763
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
26
|
D2AY43_STRRD (D2AY43) |
|
|
2e-29 |
132 |
46% |
|
- Product
- Putative uncharacterized protein
- Gene
- Sros_4149
- Organism
- Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
|
1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010] |
|
27
|
C9Z5P3_STRSW (C9Z5P3) |
|
|
2e-29 |
132 |
48% |
|
- Product
- Putative whiE protein II
- Gene
- sppH
SCAB_43291
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
28
|
E2PVZ7_STRCL (E2PVZ7) |
|
|
2e-29 |
132 |
48% |
|
- Product
- Putative WhiE II protein
- Gene
- sppH
SCLAV_4914
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot[Pubmed] 20624727 The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
30
|
F2RIV7_STRVP (F2RIV7) |
|
|
5e-29 |
130 |
50% |
|
- Product
- Polyketide cyclase WhiE II
- Gene
- SVEN_6797
- Organism
- Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
|
1uniprot[Pubmed] 21463507 Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011] |
|
34
|
F3NHY4_9ACTO (F3NHY4) |
|
|
8e-29 |
130 |
51% |
|
- Product
- Polyketide cyclase WhiE II
- Gene
- SGM_2748
- Organism
- Streptomyces griseoaurantiacus M045
|
1uniprot[Pubmed] 21551298 Draft Genome Sequence of the Marine Bacterium Streptomyces griseoaurantiacus M045, Which Produces Novel Manumycin-Type Antibiotics with a pABA Core Component.(J. Bacteriol.) [2011] |
|
36
|
C7Q5R4_CATAD (C7Q5R4) |
|
|
1e-28 |
129 |
51% |
|
- Product
- Cupin 2 conserved barrel domain protein
- Gene
- Caci_1085
- Organism
- Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
|
1uniprot Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009] |
|
40
|
C7N0D0_SACVD (C7N0D0) |
|
|
6e-28 |
127 |
48% |
|
- Product
- Putative uncharacterized protein
- Gene
- Svir_33680
- Organism
- Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
|
1uniprot Complete genome sequence of Saccharomonospora viridis type strain (P101T).(Stand. Genomic Sci.) [2009] |
|
41
|
E2EKJ8_9ACTO (E2EKJ8) |
|
|
6e-28 |
127 |
45% |
|
- Product
- Polyketide cyclase
- Gene
- sanE
- Organism
- Streptomyces sp. SANK 61196
|
1uniprot[Pubmed] 20550125 Cloning, sequencing, heterologous expression, and mechanistic analysis of A-74528 biosynthesis.(J. Am. Chem. Soc.) [2010] |
|
42
|
F4F9S4_VERMA (F4F9S4) |
|
|
1e-27 |
126 |
48% |
|
- Product
- Cupin 2 conserved barrel domain protein
- Gene
- VAB18032_23760
- Organism
- Verrucosispora maris (strain AB-18-032)
|
1uniprot[Pubmed] 21551311 Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011] |
|
44
|
D2SYZ8_MICEC (D2SYZ8) |
|
|
4e-27 |
124 |
44% |
|
- Product
- Cyclase
- Gene
-
- Organism
- Micromonospora echinospora subsp. challisensis
|
1uniprot[Pubmed] 19680283 TLN-05220, TLN-05223, new Echinosporamicin-type antibiotics, and proposed revision of the structure of bravomicins(*).(J. Antibiot.) [2009] |
|
45
|
A7DWJ0_STRTE (A7DWJ0) |
|
|
4e-27 |
124 |
47% |
|
- Product
- Putative polyketide cyclase
- Gene
- llpCII
- Organism
- Streptomyces tendae
|
1uniprot Isolation of the lysolipin gene cluster of Streptomyces tendae Tu 4042.(Gene) [2010] |
|
51
|
Q8KSW5_9ACTO (Q8KSW5) |
|
|
1e-26 |
123 |
46% |
|
- Product
- GrhS
- Gene
- grhS
- Organism
- Streptomyces sp. JP95
|
1uniprot[Pubmed] 12323376 [Medline] 22235582 A gene cluster from a marine Streptomyces encoding the biosynthesis of the aromatic spiroketal polyketide griseorhodin A.(Chem. Biol.) [2002] |
|
53
|
Q6RYW8_STRAU (Q6RYW8) |
|
|
9e-26 |
120 |
46% |
|
- Product
- WhiESaII
- Gene
- whiESaII
- Organism
- Streptomyces aureofaciens
|
1uniprot[Pubmed] 15365693 Characterization of the polyketide spore pigment cluster whiESa in Streptomyces aureofaciens CCM3239.(Arch. Microbiol.) [2004] |
|
57
|
D5UC53_CELFN (D5UC53) |
|
|
5e-23 |
110 |
44% |
|
- Product
- Cupin 2 conserved barrel domain protein
- Gene
- Cfla_3333
- Organism
- Cellulomonas flavigena (strain ATCC 482 / DSM 20109 / NCIB 8073 / NRS 134)
|
1uniprot Complete genome sequence of Cellulomonas flavigena type strain (134).(Stand. Genomic Sci.) [2010] |
|
58
|
B1GSN0_9ACTO (B1GSN0) |
|
|
3e-22 |
108 |
47% |
|
- Product
- BenD protein
- Gene
- benD
- Organism
- Streptomyces sp. A2991200
|
1uniprot[Pubmed] 17439117 Molecular analysis of the benastatin biosynthetic pathway and genetic engineering of altered fatty acid-polyketide hybrids.(J. Am. Chem. Soc.) [2007] |
|
61
|
D2MZN6_CAMJE (D2MZN6) |
|
|
0.0002 |
49.7 |
31% |
|
- Product
- Putative uncharacterized protein
- Gene
- C414_000370000
- Organism
- Campylobacter jejuni subsp. jejuni 414
|
1uniprot[Pubmed] 21418497 Genomic variations define divergence of water/wildlife-associated Campylobacter jejuni niche specialists from common clonal complexes.(Environ. Microbiol.) [2011] |
|