| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
Q56152_9ACTO (Q56152) |
|
|
1e-175 |
618 |
100% |
|
- Product
- JadW1
- Gene
- jadW1
- Organism
- Streptomyces venezuelae
|
1uniprot[Pubmed] 12904539 [Medline] 22787062 Control of growth, secondary metabolism and sporulation in Streptomyces venezuelae ISP5230 by jadW(1), a member of the afsA family of gamma-butyrolactone regulatory genes.(Microbiology) [2003] |
|
2
|
F2RC04_STRVP (F2RC04) |
|
|
1e-154 |
547 |
96% |
|
- Product
- ScbA protein
- Gene
- SVEN_5969
- Organism
- Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
|
1uniprot[Pubmed] 21463507 Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011] |
|
6
|
O24738_STRVG (O24738) |
|
|
4e-62 |
243 |
45% |
|
- Product
- BarX
- Gene
- barX
- Organism
- Streptomyces virginiae
|
1uniprot[Pubmed] 9371444 [Medline] 98037495 Butyrolactone autoregulator receptor protein (BarA) as a transcriptional regulator in Streptomyces virginiae.(J. Bacteriol.) [1997] |
|
7
|
O86851_STRCO (O86851) |
|
|
9e-61 |
238 |
45% |
|
- Product
- Biosynthetic protein
ScbA protein
- Gene
- scbA
afsA SCO6266
- Organism
- Streptomyces coelicolor
|
1uniprot[Pubmed] 12000953 [Medline] 21996410 Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002] |
|
9
|
AFSA_STRGR (P18394) |
|
|
3e-57 |
226 |
43% |
|
- Product
- Probable A-factor biosynthesis enzyme
- Gene
- afsA
- Organism
- Streptomyces griseus
|
1uniprot[Pubmed] 2492509 [Medline] 89123125 Nucleotide sequence and transcriptional analysis of the Streptomyces griseus gene (afsA) responsible for A-factor biosynthesis.(J. Bacteriol.) [1989] |
|
10
|
C0STK5_STRGR (C0STK5) |
|
|
3e-57 |
226 |
43% |
|
- Product
- AfsA
- Gene
- afsA
- Organism
- Streptomyces griseus
|
1uniprot An investigation of regulatory mechanisms of A-500359s production in mutants isolated from Streptomyces griseus SANK 60196.(Nihon Hosenkin Gakkaishi) [2009] |
|
11
|
B1VN93_STRGG (B1VN93) |
|
|
4e-57 |
226 |
43% |
|
- Product
- A-factor biosynthesis enzyme
- Gene
- afsA
SGR_6889
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
12
|
E1ARM9_STRAU (E1ARM9) |
|
|
4e-54 |
216 |
44% |
|
- Product
- AfsA-like gama-butyrolactone biosynthetic protein
- Gene
- sagA
- Organism
- Streptomyces aureofaciens
|
1uniprot[Pubmed] 21393365 The role of two SARP family transcriptional regulators in regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2011] |
|
13
|
Q83X19_STRRO (Q83X19) |
|
|
1e-51 |
208 |
39% |
|
- Product
- Gamma-butyrolactone biosynthesis protein SrrX
- Gene
- srrX
- Organism
- Streptomyces rochei
Streptomyces parvullus
|
1uniprot[Pubmed] 12791134 [Medline] 22676866 The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003] | 2uniprot[Pubmed] 10954087 [Medline] 20408175 Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000] | 3uniprot[Pubmed] 10767533 [Medline] 20231737 Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000] | 4uniprot[Pubmed] 9836424 [Medline] 99053144 Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998] | [pubmed all]
|
14
|
B0LIZ2_9ACTO (B0LIZ2) |
|
|
3e-51 |
207 |
41% |
|
- Product
- Lct9
- Gene
- lct9
- Organism
- Streptomyces rishiriensis
|
1uniprot[Pubmed] 18070976 Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit.(Antimicrob. Agents Chemother.) [2008] |
|
15
|
B5UAT3_STRLA (B5UAT3) |
|
|
3e-51 |
206 |
42% |
|
- Product
- Putative gamma-butyrolactone biosynthesis enzyme
- Gene
- farX
- Organism
- Streptomyces lavendulae
|
1uniprot Identification of genes involved in the butyrolactone autoregulator cascade that modulates secondary metabolism in Streptomyces lavendulae FRI-5.(Gene) [2008] |
|
17
|
C9Z6I5_STRSW (C9Z6I5) |
|
|
1e-50 |
204 |
40% |
|
- Product
- Putative AfsA/ScbA-like protein
- Gene
- SCAB_12081
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
19
|
O24740_STRSF (O24740) |
|
|
3e-50 |
203 |
42% |
|
- Product
- FarX
- Gene
- farX
- Organism
- Streptomyces sp. (strain FRI-5)
|
1uniprot[Pubmed] 9260956 [Medline] 97405912 Cloning and characterization of the gene (farA) encoding the receptor for an extracellular regulatory factor (IM-2) from Streptomyces sp. strain FRI-5.(J. Bacteriol.) [1997] |
|
23
|
Q84H95_STRCZ (Q84H95) |
|
|
2e-42 |
177 |
39% |
|
- Product
- Transcriptional regulator
- Gene
-
- Organism
- Streptomyces carzinostaticus subsp. neocarzinostaticus
|
1uniprot[Pubmed] 15797213 The neocarzinostatin biosynthetic gene cluster from Streptomyces carzinostaticus ATCC 15944 involving two iterative type I polyketide synthases.(Chem. Biol.) [2005] |
|
24
|
C1KEU5_9ACTO (C1KEU5) |
|
|
3e-42 |
177 |
39% |
|
- Product
- SabA
- Gene
- sabA
- Organism
- Streptomyces acidiscabies
|
1uniprot[Pubmed] 19465647 Characterization of gamma-butyrolactone autoregulatory signaling gene homologs in the angucyclinone polyketide WS5995B producer Streptomyces acidiscabies.(J. Bacteriol.) [2009] |
|
25
|
F2R407_STRVP (F2R407) |
|
|
7e-42 |
175 |
40% |
|
- Product
- Probable A-factor biosynthesis enzyme
- Gene
- SVEN_5093
- Organism
- Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
|
1uniprot[Pubmed] 21463507 Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011] |
|
27
|
E4NFG3_KITSK (E4NFG3) |
|
|
9e-41 |
172 |
38% |
|
- Product
- Putative gamma-butyrolactone biosynthesis enzyme
- Gene
- ksbS4
KSE_44600
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
34
|
E2Q7H7_STRCL (E2Q7H7) |
|
|
2e-37 |
160 |
37% |
|
- Product
- Transcriptional regulator
- Gene
- SCLAV_2310
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot[Pubmed] 20624727 The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
39
|
E4N426_KITSK (E4N426) |
|
|
9e-33 |
145 |
34% |
|
- Product
- Putative gamma-butyrolactone biosynthesis enzyme
- Gene
- ksbS2L
ksbS2R KSE_01060t KSE_75680t
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
41
|
Q0S7T6_RHOSR (Q0S7T6) |
|
|
3e-29 |
133 |
35% |
|
- Product
- Possible A-factor biosynthesis protein
- Gene
- RHA1_ro04614
- Organism
- Rhodococcus sp. (strain RHA1)
|
1uniprot[Pubmed] 17030794 The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse.(Proc. Natl. Acad. Sci. U.S.A.) [2006] |
|
43
|
Q2VQT2_9ACTO (Q2VQT2) |
|
|
9e-28 |
129 |
34% |
|
- Product
- AfsA/ScbA-like protein
- Gene
- sngA
- Organism
- Streptomyces natalensis
|
1uniprot[Pubmed] 16228193 Cloning and in vivo functional analysis by disruption of a gene encoding the gamma-butyrolactone autoregulator receptor from Streptomyces natalensis.(Arch. Microbiol.) [2005] |
|
46
|
Q82KU4_STRAW (Q82KU4) |
|
|
6e-23 |
112 |
33% |
|
- Product
- Putative gamma-butyrolactone biosynthesis protein
- Gene
- avaA
SAV2269 SAV_2269
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
48
|
E4WAH1_RHOE1 (E4WAH1) |
|
|
2e-19 |
101 |
30% |
|
- Product
- Putative A-factor biosynthesis protein
- Gene
- REQ_44790
- Organism
- Rhodococcus equi (strain 103S)
Corynebacterium equi
|
1uniprot[Pubmed] 20941392 The genome of a pathogenic rhodococcus: cooptive virulence underpinned by key gene acquisitions.(PLoS Genet.) [2010] |
|
49
|
C0ZSB7_RHOE4 (C0ZSB7) |
|
|
2e-17 |
94.7 |
27% |
|
- Product
- Putative uncharacterized protein
- Gene
- RER_54010
- Organism
- Rhodococcus erythropolis (strain PR4 / NBRC 100887)
|
1uniprot Sequence analysis of three plasmids harboured in Rhodococcus erythropolis strain PR4.(Environ. Microbiol.) [2006] |
|
50
|
C9ZCC6_STRSW (C9ZCC6) |
|
|
3e-17 |
93.6 |
31% |
|
- Product
- Putative secondary metabolite corepressor
- Gene
- SCAB_63111
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
55
|
E2Q9C7_STRCL (E2Q9C7) |
|
|
1e-14 |
85.5 |
30% |
|
- Product
- Gamma-butyrolactone biosynthesis protein
- Gene
- avaA2
SCLAV_0471
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot[Pubmed] 20624727 The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
56
|
E4NA86_KITSK (E4NA86) |
|
|
1e-13 |
82 |
30% |
|
- Product
- Putative gamma-butyrolactone biosynthesis enzyme
- Gene
- ksbS3
KSE_22970
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
57
|
D7B3K8_NOCDD (D7B3K8) |
|
|
2e-13 |
81.6 |
29% |
|
- Product
- A-factor biosynthesis repeat-containing protein
- Gene
- Ndas_3370
- Organism
- Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei
|
1uniprot Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010] |
|
58
|
Q9JN90_STRCO (Q9JN90) |
|
|
2e-13 |
81.6 |
33% |
|
- Product
- 2-Alkyl-4-hydroxymethylfuran-3-carboxylic acid biosynthesis protein, MmfL
Putative uncharacterized protein mmfL
- Gene
- mmfL
SCP1.243
- Organism
- Streptomyces coelicolor
|
1uniprot[Pubmed] 12000953 [Medline] 21996410 Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002] | 2uniprot[Pubmed] 2828187 [Medline] 88112873 Nucleotide sequence analysis reveals similarities between proteins determining methylenomycin A resistance in Streptomyces and tetracycline resistance in eubacteria.(Gene) [1987] | 3uniprot[Pubmed] 2992952 [Medline] 85284984 Resistance, regulatory and production genes for the antibiotic methylenomycin are clustered.(EMBO J.) [1985] | [pubmed all]
|
59
|
F2RHE1_STRVP (F2RHE1) |
|
|
6e-13 |
79.7 |
29% |
|
- Product
- A-factor biosynthesis protein AfsA
- Gene
- SVEN_4183
- Organism
- Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
|
1uniprot[Pubmed] 21463507 Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011] |
|
62
|
Q1RQN9_STRAM (Q1RQN9) |
|
|
6e-12 |
76.3 |
29% |
|
- Product
- AfsA-like protein
- Gene
- SAML0196
SAML0197 SAMR0196 SAMR0197
- Organism
- Streptomyces ambofaciens ATCC 23877
|
1uniprot[Pubmed] 16952952 Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006] | 2uniprot[Pubmed] 16956972 Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006] | 3uniprot Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006] | [pubmed all]
|
66
|
A1RA10_ARTAT (A1RA10) |
|
|
3e-07 |
60.8 |
25% |
|
- Product
- Putative A-factor biosynthesis repeat family protein
- Gene
- AAur_3376
- Organism
- Arthrobacter aurescens (strain TC1)
|
1uniprot[Pubmed] 17194220 Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1.(PLoS Genet.) [2006] |
|
67
|
B5BRA8_9ACTO (B5BRA8) |
|
|
2e-06 |
58.2 |
28% |
|
- Product
- A-factor biosynthesis protein AfsA homolog
- Gene
- afsA
- Organism
- Streptomyces albulus
|
1uniprot[Pubmed] 18997795 Epsilon-poly-L-lysine dispersity is controlled by a highly unusual nonribosomal peptide synthetase.(Nat. Chem. Biol.) [2008] |
|
68
|
D7C007_STRBB (D7C007) |
|
|
4e-06 |
56.6 |
28% |
|
- Product
- Putative AfsA/ScbA-like protein
- Gene
- SBI_08929
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
73
|
C9ZCB8_STRSW (C9ZCB8) |
|
|
0.0002 |
51.2 |
26% |
|
- Product
- Putative uncharacterized protein
- Gene
- SCAB_63031
- Organism
- Streptomyces scabies (strain 87.22)
Streptomyces scabiei
|
1uniprot[Pubmed] 20064060 Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010] |
|
74
|
Q7NCZ7_GLOVI (Q7NCZ7) |
|
|
0.0002 |
51.2 |
32% |
|
- Product
- Gll2829 protein
- Gene
- gll2829
- Organism
- Gloeobacter violaceus
|
1uniprot[Pubmed] 14621292 [Medline] 22977040 Complete genome structure of Gloeobacter violaceus PCC 7421, a cyanobacterium that lacks thylakoids.(DNA Res.) [2003] |
|
75
|
E2Q9B9_STRCL (E2Q9B9) |
|
|
0.0004 |
50.1 |
27% |
|
- Product
- Putative gamma-butyrolactone biosynthesis protein
- Gene
- avaA1
SCLAV_0463
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot[Pubmed] 20624727 The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|