BLAST table : Ovied_00090

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 Q6ZZW4_STRAT
(Q6ZZW4)		 
[query] 1 - 494 (494)
[subject] 1 - 494 (494)
 0.0 975   100% Oxygenase ovmOI Streptomyces antibioticus
2
 C4NYJ7_9ACTO
(C4NYJ7)		 
[query] 6 - 493 (494)
[subject] 1 - 490 (490)
 0.0 666   70% SaqE saqE Micromonospora sp. Tu 6368
3
 Q2HR18_9ACTO
(Q2HR18)		 Jump to Sch475_00400 
[query] 6 - 494 (494)
[subject] 1 - 490 (494)
 0.0 652   68% Putative oxygenase schP10 Streptomyces sp. SCC 2136
4
 Q54171_STRFR
(Q54171)		 Jump to Urd_00100 
[query] 6 - 494 (494)
[subject] 1 - 491 (495)
 1e-179 632   68% Putative oxygenase UrdE Streptomyces fradiae
Streptomyces roseoflavus
5
 D0VWY3_9ACTO
(D0VWY3)		 
[query] 21 - 494 (494)
[subject] 1 - 474 (474)
 1e-178 628   68% Polyketide oxygenase CabE cabe Streptomyces 1.14.13.-
6
 D9W579_9ACTO
(D9W579)		 
[query] 6 - 491 (494)
[subject] 1 - 487 (489)
 1e-178 628   67% Aur1A SSNG_07309 Streptomyces sp. C
7
 Q9AMJ5_STRAT
(Q9AMJ5)		 
[query] 6 - 494 (494)
[subject] 1 - 489 (491)
 1e-177 625   67% Putative oxygenase SimA7 simA7 Streptomyces antibioticus
8
 Q56HA5_STRAU
(Q56HA5)		 
[query] 6 - 493 (494)
[subject] 1 - 488 (488)
 1e-176 622   66% Aur1A aur1A Streptomyces aureofaciens
9
 D1XRE7_9ACTO
(D1XRE7)		 
[query] 6 - 493 (494)
[subject] 1 - 488 (489)
 1e-172 610   64% Monooxygenase FAD-binding SACTEDRAFT_5257 Streptomyces sp. SA3_actE
10
 D2XDX3_9PSEU
(D2XDX3)		 
[query] 6 - 493 (494)
[subject] 1 - 487 (489)
 1e-172 610   63% AzicO3 azicO3 Kibdelosporangium sp. MJ126-NF4
11
 Q93LY7_9ACTO
(Q93LY7)		 
[query] 6 - 491 (494)
[subject] 1 - 486 (491)
 1e-172 610   66% Polyketide oxygenase PgaE pgaE Streptomyces sp. PGA64
12
 Q84CI4_9ACTO
(Q84CI4)		 
[query] 6 - 494 (494)
[subject] 1 - 488 (488)
 1e-170 603   63% Oxygenase-like protein pd2O Streptomyces sp. WP 4669
13
 D7RFJ3_AMYOR
(D7RFJ3)		 
[query] 6 - 493 (494)
[subject] 1 - 485 (487)
 1e-168 595   68% Putative oxygenase bexE Amycolatopsis orientalis subsp. vinearia
14
 Q47QL5_THEFY
(Q47QL5)		 
[query] 6 - 491 (494)
[subject] 1 - 483 (486)
 1e-167 592   62% Putative uncharacterized protein Tfu_1216 Thermobifida fusca (strain YX)
15
 D2XDX8_9PSEU
(D2XDX8)		 
[query] 6 - 494 (494)
[subject] 7 - 492 (503)
 1e-166 590   62% AzicO4 azicO4 Kibdelosporangium sp. MJ126-NF4
16
 C7QAE9_CATAD
(C7QAE9)		 
[query] 6 - 493 (494)
[subject] 1 - 487 (489)
 1e-165 587   62% Monooxygenase FAD-binding Caci_3543 Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
17
 Q9ZGD9_STRCY
(Q9ZGD9)		 Jump to Lando_00010 
[query] 6 - 494 (494)
[subject] 1 - 486 (491)
 1e-161 571   62% Oxygenase homolog lanE Streptomyces cyanogenus
18
 D1H0K5_9ACTO
(D1H0K5)		 
[query] 7 - 491 (494)
[subject] 9 - 492 (503)
 1e-158 563   61% Putative monooxygenase ravOI Streptomyces sp. C23201NS3
19
 F2RC22_STRVP
(F2RC22)		 
[query] 7 - 473 (494)
[subject] 13 - 485 (544)
 1e-157 559   61% 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases SVEN_5987 Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
20
 Q5U913_9ACTO
(Q5U913)		 Jump to Jado_00150 
[query] 6 - 473 (494)
[subject] 9 - 482 (541)
 1e-156 556   60% JadH jadH Streptomyces venezuelae
21
 Q84CJ1_9ACTO
(Q84CJ1)		 
[query] 6 - 493 (494)
[subject] 1 - 493 (495)
 1e-150 537   59% Oxygenase-like protein kinO2 Streptomyces murayamaensis
22
 Q6VMJ3_STRAM
(Q6VMJ3)		 
[query] 1 - 494 (494)
[subject] 1 - 508 (508)
 1e-149 531   57% Putative oxygenase alpG
DSMT0179		 Streptomyces ambofaciens
23
 Q1RQS6_STRAM
(Q1RQS6)		 
[query] 1 - 494 (494)
[subject] 1 - 508 (508)
 1e-149 531   57% Putative oxygenase alpG
SAMT0159
SAMT0160		 Streptomyces ambofaciens ATCC 23877
24
 D1H096_9ACTO
(D1H096)		 
[query] 4 - 493 (494)
[subject] 17 - 501 (513)
 1e-147 526   59% Putative FAD-dependent monooxygenase chryOI Streptomyces albaduncus
25
 F6K0V9_9BACT
(F6K0V9)		 
[query] 10 - 491 (494)
[subject] 1 - 477 (482)
 1e-146 521   58% Oxygenase uncultured bacterium BAC AB649/1850
26
 D6XAW9_9ACTO
(D6XAW9)		 
[query] 21 - 477 (494)
[subject] 1 - 455 (510)
 1e-144 517   59% Monooxygenase, FAD-binding SSEG_11168 Streptomyces sviceus ATCC 29083
27
 D5MRJ1_9ACTO
(D5MRJ1)		 
[query] 33 - 493 (494)
[subject] 1 - 459 (460)
 1e-143 512   59% Putative oxygenase hrbR Streptomyces sp. 2238-SVT4
28
 A4X700_SALTO
(A4X700)		 
[query] 6 - 491 (494)
[subject] 4 - 490 (492)
 1e-142 509   55% Monooxygenase, FAD-binding Strop_2199 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
29
 A4X6Z7_SALTO
(A4X6Z7)		 
[query] 6 - 494 (494)
[subject] 1 - 488 (503)
 1e-142 508   57% Monooxygenase, FAD-binding Strop_2196 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
30
 F6K0X0_9BACT
(F6K0X0)		 
[query] 1 - 494 (494)
[subject] 1 - 496 (496)
 1e-140 503   57% Oxygenase-like protein uncultured bacterium BAC AB649/1850
31
 Q84CK0_9ACTO
(Q84CK0)		 
[query] 7 - 491 (494)
[subject] 5 - 486 (489)
 1e-140 501   54% Oxygenase-like protein kinO1 Streptomyces murayamaensis
32
 Q6VMI4_STRAM
(Q6VMI4)		 
[query] 5 - 493 (494)
[subject] 3 - 490 (491)
 1e-138 497   55% Putative oxygenase alpK
DSMT0188		 Streptomyces ambofaciens
33
 Q1RQR7_STRAM
(Q1RQR7)		 
[query] 5 - 493 (494)
[subject] 3 - 490 (491)
 1e-138 497   55% Putative oxygenase alpK
SAMT0168
SAMT0169		 Streptomyces ambofaciens ATCC 23877
34
 B5HT27_9ACTO
(B5HT27)		 
[query] 10 - 491 (494)
[subject] 8 - 485 (490)
 1e-137 492   54% Monooxygenase SSEG_02744 Streptomyces sviceus ATCC 29083
35
 Q1RQU6_STRAM
(Q1RQU6)		 
[query] 11 - 493 (494)
[subject] 6 - 484 (486)
 1e-136 489   56% Putative oxygenase SAMT0139
SAMT0140		 Streptomyces ambofaciens ATCC 23877
36
 Q0JWC6_STRAM
(Q0JWC6)		 
[query] 11 - 493 (494)
[subject] 6 - 484 (486)
 1e-136 488   56% Putative oxygenase DSMT0159 Streptomyces ambofaciens
37
 Q0JWC9_STRAM
(Q0JWC9)		 
[query] 11 - 491 (494)
[subject] 6 - 487 (504)
 1e-136 488   56% Putative oxygenase DSMT0156 Streptomyces ambofaciens
38
 Q1RQU9_STRAM
(Q1RQU9)		 
[query] 11 - 491 (494)
[subject] 6 - 487 (504)
 1e-135 488   56% Putative oxygenase SAMT0136
SAMT0137		 Streptomyces ambofaciens ATCC 23877
39
 F6K0Y2_9BACT
(F6K0Y2)		 
[query] 6 - 491 (494)
[subject] 4 - 491 (495)
 1e-133 480   56% Monooxygenase uncultured bacterium BAC AB649/1850
40
 F6K0X5_9BACT
(F6K0X5)		 
[query] 10 - 492 (494)
[subject] 5 - 486 (491)
 1e-123 445   53% Putative oxygenase uncultured bacterium BAC AB649/1850
41
 E4NFG7_KITSK
(E4NFG7)		 
[query] 6 - 434 (494)
[subject] 1 - 431 (889)
 1e-119 433   57% Putative oxidoreductase KSE_44640 Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
42
 C4NYK4_9ACTO
(C4NYK4)		 
[query] 10 - 491 (494)
[subject] 1 - 481 (491)
 1e-118 431   52% SaqM saqM Micromonospora sp. Tu 6368
43
 Q84CJ2_9ACTO
(Q84CJ2)		 
[query] 6 - 493 (494)
[subject] 6 - 489 (490)
 1e-115 420   50% Oxygenase reductase-like protein kinOR Streptomyces murayamaensis
44
 A4X6Y9_SALTO
(A4X6Y9)		 
[query] 10 - 491 (494)
[subject] 5 - 480 (503)
 1e-115 419   49% Monooxygenase, FAD-binding Strop_2188 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
45
 Q6ZZV7_STRAT
(Q6ZZV7)		 Jump to Ovied_00160 
[query] 10 - 491 (494)
[subject] 5 - 486 (490)
 1e-113 415   51% Oxygenase ovmOII Streptomyces antibioticus
46
 Q6DV91_STRGL
(Q6DV91)		 
[query] 20 - 493 (494)
[subject] 20 - 493 (749)
 1e-112 412   50% Bifunctional oxygenase-reductase protein LndM2 Streptomyces globisporus
47
 A4X6Z0_SALTO
(A4X6Z0)		 
[query] 6 - 491 (494)
[subject] 1 - 482 (490)
 1e-112 411   49% Monooxygenase, FAD-binding Strop_2189 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
48
 Q6DV92_STRCY
(Q6DV92)		 Jump to Lando_00080 
[query] 1 - 491 (494)
[subject] 1 - 491 (743)
 1e-111 406   48% Bifunctional oxygenase-reductase protein LanM2 Streptomyces cyanogenus
49
 Q9ZGD2_STRCY
(Q9ZGD2)		 
[query] 1 - 491 (494)
[subject] 1 - 491 (522)
 1e-110 405   48% Oxygenase homolog lanM Streptomyces cyanogenus
50
 Q0RMN5_FRAAA
(Q0RMN5)		 
[query] 1 - 494 (494)
[subject] 6 - 508 (526)
 1e-110 403   49% Putative polyketide oxygenase/hydroxylase FRAAL2565 Frankia alni (strain ACN14a) 1.14.13.-
51
 Q93FA8_STRAT
(Q93FA8)		 
[query] 10 - 493 (494)
[subject] 8 - 491 (494)
 1e-107 393   49% Sim7 sim7 Streptomyces antibioticus
52
 Q56H97_STRAU
(Q56H97)		 
[query] 1 - 493 (494)
[subject] 1 - 492 (774)
 1e-106 390   49% Aur1I aur1I Streptomyces aureofaciens
53
 D1XRF4_9ACTO
(D1XRF4)		 
[query] 20 - 491 (494)
[subject] 18 - 483 (768)
 1e-103 382   50% Monooxygenase FAD-binding SACTEDRAFT_5264 Streptomyces sp. SA3_actE
54
 Q0JWA6_STRAM
(Q0JWA6)		 
[query] 20 - 494 (494)
[subject] 20 - 491 (491)
 1e-103 380   48% Putative oxygenase DSMT0180 Streptomyces ambofaciens
55
 F2RC20_STRVP
(F2RC20)		 
[query] 5 - 491 (494)
[subject] 23 - 507 (512)
 1e-103 379   50% 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases SVEN_5985 Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
56
 Q5U915_9ACTO
(Q5U915)		 Jump to Jado_00130 
[query] 5 - 491 (494)
[subject] 23 - 507 (512)
 1e-103 379   50% JadF jadF Streptomyces venezuelae
57
 Q6VMJ2_STRAM
(Q6VMJ2)		 
[query] 20 - 494 (494)
[subject] 20 - 491 (491)
 1e-102 378   48% Putative oxygenase alpF Streptomyces ambofaciens
58
 Q1RQS5_STRAM
(Q1RQS5)		 
[query] 20 - 494 (494)
[subject] 20 - 491 (491)
 1e-102 378   48% Putative oxygenase alpF
SAMT0160
SAMT0161		 Streptomyces ambofaciens ATCC 23877
59
 D2ASL9_STRRD
(D2ASL9)		 
[query] 6 - 491 (494)
[subject] 1 - 490 (494)
 1e-101 375   48% Putative monooxygenase Sros_5796 Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
60
 D1H0A0_9ACTO
(D1H0A0)		 
[query] 10 - 491 (494)
[subject] 12 - 490 (491)
 1e-101 375   48% Putative FAD-dependent monooxygenase chryOIV Streptomyces albaduncus
61
 Q7X2G6_9ACTO
(Q7X2G6)		 Jump to Gilvo_00160 
[query] 8 - 491 (494)
[subject] 13 - 496 (500)
 1e-101 372   45% Putative FAD-dependent oxygenase gilOI Streptomyces griseoflavus
62
 Q93LX9_9ACTO
(Q93LX9)		 
[query] 20 - 490 (494)
[subject] 20 - 492 (784)
 1e-99 369   48% Oxygenase-reductase PgaM pgaM Streptomyces sp. PGA64
63
 Q56156_9ACTO
(Q56156)		 
[query] 5 - 491 (494)
[subject] 23 - 520 (525)
 2e-98 364   48% C-16 hydroxylase Streptomyces venezuelae
64
 Q84CH7_9ACTO
(Q84CH7)		 
[query] 20 - 492 (494)
[subject] 21 - 490 (764)
 5e-98 363   49% Oxygenase reductase-like protein pd2OR Streptomyces sp. WP 4669
65
 A9FKP5_SORC5
(A9FKP5)		 
[query] 6 - 490 (494)
[subject] 1 - 502 (512)
 1e-96 358   45% Putative monooxygenase yhjG3
sce4973		 Sorangium cellulosum (strain So ce56)
Polyangium cellulosum (strain So ce56)
66
 D9W585_9ACTO
(D9W585)		 
[query] 20 - 494 (494)
[subject] 1 - 484 (771)
 2e-96 357   47% Aur1I SSNG_07315 Streptomyces sp. C
67
 Q9AMI8_STRAT
(Q9AMI8)		 
[query] 10 - 493 (494)
[subject] 8 - 491 (494)
 3e-96 357   47% Putative oxygenase SimA8 simA8 Streptomyces antibioticus
68
 Q9F6D1_9ACTO
(Q9F6D1)		 Jump to R1128_00110 
[query] 6 - 491 (494)
[subject] 1 - 492 (524)
 3e-95 353   43% Oxygenase zhuK Streptomyces sp. R1128
69
 F8B4A6_9ACTO
(F8B4A6)		 
[query] 10 - 490 (494)
[subject] 22 - 543 (569)
 3e-94 350   46% Monooxygenase FAD-binding protein FsymDg_1940 Frankia symbiont of Datisca glomerata
70
 B1MEV3_MYCA9
(B1MEV3)		 
[query] 10 - 494 (494)
[subject] 6 - 487 (493)
 9e-94 348   44% Putative oxygenase MAB_3483 Mycobacterium abscessus (strain ATCC 19977 / DSM 44196)
71
 C1A6J2_GEMAT
(C1A6J2)		 
[query] 5 - 491 (494)
[subject] 1 - 494 (499)
 7e-93 346   46% Putative oxygenase GAU_0810 Gemmatimonas aurantiaca (strain T-27 / DSM 14586 / JCM 11422 / NBRC 100505)
72
 D2XDY4_9PSEU
(D2XDY4)		 
[query] 7 - 491 (494)
[subject] 3 - 448 (451)
 7e-93 346   45% AzicO5 azicO5 Kibdelosporangium sp. MJ126-NF4
73
 Q3S8P7_STRRM
(Q3S8P7)		 Jump to Oxtet_00190 
[query] 10 - 492 (494)
[subject] 5 - 500 (503)
 2e-92 345   45% OxyS oxyS Streptomyces rimosus
74
 D8I7G5_AMYMU
(D8I7G5)		 
[query] 2 - 491 (494)
[subject] 4 - 504 (514)
 4e-92 343   44% 3-(3-hydroxy-phenyl)propionate hydroxylase mhpA
AMED_5632		 Amycolatopsis mediterranei (strain U-32)
75
 F6K0W0_9BACT
(F6K0W0)		 
[query] 10 - 492 (494)
[subject] 10 - 483 (501)
 6e-91 339   46% Oxygenase reductase-like protein uncultured bacterium BAC AB649/1850
76
 Q58PK7_STRRM
(Q58PK7)		 
[query] 10 - 492 (494)
[subject] 5 - 500 (503)
 7e-91 339   45% Anhydrotetracycline oxygenase otcC Streptomyces rimosus
77
 D6A6R4_9ACTO
(D6A6R4)		 
[query] 8 - 491 (494)
[subject] 2 - 471 (475)
 3e-90 337   45% Flavin-type hydroxylase SSFG_05082 Streptomyces ghanaensis ATCC 14672
78
 A4FIN7_SACEN
(A4FIN7)		 
[query] 8 - 494 (494)
[subject] 2 - 475 (475)
 1e-89 335   45% Monooxygenase, FAD-binding protein SACE_4643 Saccharopolyspora erythraea (strain NRRL 23338)
79
 D6B8J3_9ACTO
(D6B8J3)		 
[query] 8 - 491 (494)
[subject] 2 - 474 (479)
 3e-88 330   44% Monooxygenase SSHG_02578 Streptomyces albus J1074
80
 D9VZY3_9ACTO
(D9VZY3)		 
[query] 10 - 491 (494)
[subject] 1 - 478 (484)
 5e-88 330   46% Flavin-type hydroxylase SSNG_02995 Streptomyces sp. C
81
 B4VBQ8_9ACTO
(B4VBQ8)		 
[query] 10 - 493 (494)
[subject] 1 - 470 (474)
 7e-88 329   45% Flavin-type hydroxylase SSAG_05179 Streptomyces sp. Mg1
82
 B1MIC9_MYCA9
(B1MIC9)		 
[query] 10 - 494 (494)
[subject] 6 - 488 (489)
 1e-87 328   45% Putative monooxygenase MAB_0857 Mycobacterium abscessus (strain ATCC 19977 / DSM 44196)
83
 D9X8G8_STRVR
(D9X8G8)		 
[query] 10 - 493 (494)
[subject] 4 - 473 (475)
 1e-87 328   44% Monooxygenase SSQG_04724 Streptomyces viridochromogenes DSM 40736
84
 F8JJJ6_STRCT
(F8JJJ6)		 
[query] 6 - 474 (494)
[subject] 1 - 477 (502)
 1e-87 328   44% Putative monooxygenase SCAT_p1249 Streptomyces cattleya NRRL 8057
85
 F2R776_STRVP
(F2R776)		 
[query] 10 - 493 (494)
[subject] 4 - 473 (476)
 2e-87 328   45% Rifampin monooxygenase SVEN_0481 Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
86
 D9WLJ0_9ACTO
(D9WLJ0)		 
[query] 8 - 493 (494)
[subject] 2 - 478 (480)
 2e-87 328   44% Monooxygenase, FAD-binding SSOG_01305 Streptomyces himastatinicus ATCC 53653
87
 D3UA07_9ACTO
(D3UA07)		 
[query] 6 - 474 (494)
[subject] 1 - 479 (507)
 2e-87 328   44% FAD-dependent monooxygenase Streptomyces flaveolus
88
 Q8KY40_STRCU
(Q8KY40)		 
[query] 6 - 491 (494)
[subject] 22 - 516 (518)
 2e-87 327   43% RubN rubN Streptomyces collinus
89
 B5ZNX8_RHILW
(B5ZNX8)		 
[query] 5 - 491 (494)
[subject] 1 - 494 (497)
 4e-87 327   44% Monooxygenase FAD-binding Rleg2_1649 Rhizobium leguminosarum bv. trifolii (strain WSM2304)
90
 D6XAX0_9ACTO
(D6XAX0)		 
[query] 56 - 491 (494)
[subject] 1 - 431 (437)
 6e-87 326   47% Bifunctional oxygenase-reductase LndM2 SSEG_11169 Streptomyces sviceus ATCC 29083
91
 F8UVQ9_9BACT
(F8UVQ9)		 
[query] 10 - 492 (494)
[subject] 7 - 496 (500)
 8e-87 325   42% Putative rifampin monooxygenase uncultured bacterium
92
 Q70J79_STRGR
(Q70J79)		 Jump to Chro_00190 
[query] 6 - 491 (494)
[subject] 1 - 501 (506)
 9e-87 325   44% Oxygenase cmmOIV Streptomyces griseus subsp. griseus
93
 Q73ZB8_MYCPA
(Q73ZB8)		 
[query] 10 - 492 (494)
[subject] 38 - 520 (525)
 1e-86 325   45% Putative uncharacterized protein MAP_1685 Mycobacterium paratuberculosis
94
 E3JBU3_FRASU
(E3JBU3)		 
[query] 20 - 492 (494)
[subject] 15 - 487 (505)
 1e-86 325   43% Monooxygenase FAD-binding protein FraEuI1c_4254 Frankia sp. (strain EuI1c)
95
 Q8KU28_9NOCA
(Q8KU28)		 
[query] 8 - 493 (494)
[subject] 2 - 473 (475)
 1e-86 325   44% Flavin-type hydroxylase Rhodococcus sp. NCIMB 9784
96
 D8HR95_AMYMU
(D8HR95)		 
[query] 10 - 491 (494)
[subject] 5 - 501 (504)
 2e-86 324   43% FAD-dependent oxidoreductase AMED_4222 Amycolatopsis mediterranei (strain U-32)
97
 F7PEN4_MYCPA
(F7PEN4)		 
[query] 10 - 492 (494)
[subject] 16 - 498 (503)
 3e-86 324   45% 2-polyprenyl-6-methoxyphenol hydroxylase-like oxidoreductase MAPs_23100 Mycobacterium avium subsp. paratuberculosis S397
98
 D5P4B5_9MYCO
(D5P4B5)		 
[query] 6 - 491 (494)
[subject] 7 - 492 (499)
 3e-86 323   44% Monooxygenase HMPREF0591_1009 Mycobacterium parascrofulaceum ATCC BAA-614
99
 A0QG87_MYCA1
(A0QG87)		 
[query] 10 - 492 (494)
[subject] 16 - 498 (503)
 3e-86 323   45% Flavin-type hydroxylase MAV_2736 Mycobacterium avium (strain 104)
100
 Q194P4_STRAA
(Q194P4)		 Jump to Mith_00310 
[query] 20 - 492 (494)
[subject] 25 - 507 (533)
 3e-86 323   45% Oxygenase mtmOIV Streptomyces argillaceus
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
2
 C4NYJ7_9ACTO
(C4NYJ7)		 
[query] 6 - 493 (494)
[subject] 1 - 490 (490)
 0.0 666   70%
Product
SaqE
Gene
saqE
Organism
Micromonospora sp. Tu 6368
1uniprot[Pubmed] 17497146
A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
2uniprot[Pubmed] 19384899
Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009]
[pubmed all]
3
 Q2HR18_9ACTO
(Q2HR18)		 Jump to Sch475_00400 
[query] 6 - 494 (494)
[subject] 1 - 490 (494)
 0.0 652   68%
Product
Putative oxygenase
Gene
schP10
Organism
Streptomyces sp. SCC 2136
1uniprot
Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: Cloning, Sequencing, and Characterization.(Mol. Cells) [2006]
2uniprot
Molecular cloning and characterization of biosynthetic genes cluster of Sch 47554 from Streptomyces sp. SCC 2136. [2004]
4
 Q54171_STRFR
(Q54171)		 Jump to Urd_00100 
[query] 6 - 494 (494)
[subject] 1 - 491 (495)
 1e-179 632   68%
Product
Putative oxygenase
Gene
UrdE
Organism
Streptomyces fradiae
Streptomyces roseoflavus
1uniprot[Pubmed] 7592377 [Medline] 96042088
Cloning and characterization of a polyketide synthase from Streptomyces fradiae Tue2717 encoding the genes for biosynthesis of the angucycline antibiotic urdamycin A and a gene probably involved in its oxygenation.(J. Bacteriol.) [1995]
5
 D0VWY3_9ACTO
(D0VWY3)		 
[query] 21 - 494 (494)
[subject] 1 - 474 (474)
 1e-178 628   68%
Product
Polyketide oxygenase CabE
Gene
cabe
Organism
Streptomyces
1uniprot[Pubmed] 17669423
Crystal structures of two aromatic hydroxylases involved in the early tailoring steps of angucycline biosynthesis.(J. Mol. Biol.) [2007]
7
 Q9AMJ5_STRAT
(Q9AMJ5)		 
[query] 6 - 494 (494)
[subject] 1 - 489 (491)
 1e-177 625   67%
Product
Putative oxygenase SimA7
Gene
simA7
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 11959542 [Medline] 21955989
Biosynthetic gene cluster of simocyclinone, a natural multihybrid antibiotic.(Antimicrob. Agents Chemother.) [2002]
8
 Q56HA5_STRAU
(Q56HA5)		 
[query] 6 - 493 (494)
[subject] 1 - 488 (488)
 1e-176 622   66%
Product
Aur1A
Gene
aur1A
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 12384301 [Medline] 22271582
Cloning and characterization of a polyketide synthase gene cluster involved in biosynthesis of a proposed angucycline-like polyketide auricin in Streptomyces aureofaciens CCM 3239.(Gene) [2002]
2uniprot[Pubmed] 16079347
Characterization of a regulatory gene essential for the production of the angucycline-like polyketide antibiotic auricin in Streptomyces aureofaciens CCM 3239.(Microbiology) [2005]
3uniprot[Pubmed] 20466770
The role of the TetR-family transcriptional regulator Aur1R in negative regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2010]
[pubmed all]
10
 D2XDX3_9PSEU
(D2XDX3)		 
[query] 6 - 493 (494)
[subject] 1 - 487 (489)
 1e-172 610   63%
Product
AzicO3
Gene
azicO3
Organism
Kibdelosporangium sp. MJ126-NF4
1uniprot[Pubmed] 19928906
Biosynthetic studies of aziridine formation in azicemicins.(J. Am. Chem. Soc.) [2009]
11
 Q93LY7_9ACTO
(Q93LY7)		 
[query] 6 - 491 (494)
[subject] 1 - 486 (491)
 1e-172 610   66%
Product
Polyketide oxygenase PgaE
Gene
pgaE
Organism
Streptomyces sp. PGA64
1uniprot[Pubmed] 12654660 [Medline] 22540650
Engineering anthracycline biosynthesis toward angucyclines.(Antimicrob. Agents Chemother.) [2003]
2uniprot[Pubmed] 15515887
Partial activation of a silent angucycline-type gene cluster from a rubromycin beta producing Streptomyces sp. PGA64.(J. Antibiot.) [2004]
3uniprot[Pubmed] 17669423
Crystal structures of two aromatic hydroxylases involved in the early tailoring steps of angucycline biosynthesis.(J. Mol. Biol.) [2007]
[pubmed all]
13
 D7RFJ3_AMYOR
(D7RFJ3)		 
[query] 6 - 493 (494)
[subject] 1 - 485 (487)
 1e-168 595   68%
Product
Putative oxygenase
Gene
bexE
Organism
Amycolatopsis orientalis subsp. vinearia
1uniprot[Pubmed] 20443562
A biosynthetic pathway for BE-7585A, a 2-thiosugar-containing angucycline-type natural product.(J. Am. Chem. Soc.) [2010]
14
 Q47QL5_THEFY
(Q47QL5)		 
[query] 6 - 491 (494)
[subject] 1 - 483 (486)
 1e-167 592   62%
Product
Putative uncharacterized protein
Gene
Tfu_1216
Organism
Thermobifida fusca (strain YX)
1uniprot[Pubmed] 17209016
Genome sequence and analysis of the soil cellulolytic actinomycete Thermobifida fusca YX.(J. Bacteriol.) [2007]
15
 D2XDX8_9PSEU
(D2XDX8)		 
[query] 6 - 494 (494)
[subject] 7 - 492 (503)
 1e-166 590   62%
Product
AzicO4
Gene
azicO4
Organism
Kibdelosporangium sp. MJ126-NF4
1uniprot[Pubmed] 19928906
Biosynthetic studies of aziridine formation in azicemicins.(J. Am. Chem. Soc.) [2009]
16
 C7QAE9_CATAD
(C7QAE9)		 
[query] 6 - 493 (494)
[subject] 1 - 487 (489)
 1e-165 587   62%
Product
Monooxygenase FAD-binding
Gene
Caci_3543
Organism
Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
1uniprot
Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009]
17
 Q9ZGD9_STRCY
(Q9ZGD9)		 Jump to Lando_00010 
[query] 6 - 494 (494)
[subject] 1 - 486 (491)
 1e-161 571   62%
Product
Oxygenase homolog
Gene
lanE
Organism
Streptomyces cyanogenus
1uniprot[Pubmed] 9933932 [Medline] 99132695
Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis.(FEMS Microbiol. Lett.) [1999]
19
 F2RC22_STRVP
(F2RC22)		 
[query] 7 - 473 (494)
[subject] 13 - 485 (544)
 1e-157 559   61%
Product
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Gene
SVEN_5987
Organism
Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]
20
 Q5U913_9ACTO
(Q5U913)		 Jump to Jado_00150 
[query] 6 - 473 (494)
[subject] 9 - 482 (541)
 1e-156 556   60%
Product
JadH
Gene
jadH
Organism
Streptomyces venezuelae
1uniprot[Pubmed] 15817470
Functional analyses of oxygenases in jadomycin biosynthesis and identification of JadH as a bifunctional oxygenase/dehydrase.(J. Biol. Chem.) [2005]
22
 Q6VMJ3_STRAM
(Q6VMJ3)		 
[query] 1 - 494 (494)
[subject] 1 - 508 (508)
 1e-149 531   57%
Product
Putative oxygenase
Gene
alpG
DSMT0179
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 14742212
Functional angucycline-like antibiotic gene cluster in the terminal inverted repeats of the Streptomyces ambofaciens linear chromosome.(Antimicrob. Agents Chemother.) [2004]
2uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
[pubmed all]
23
 Q1RQS6_STRAM
(Q1RQS6)		 
[query] 1 - 494 (494)
[subject] 1 - 508 (508)
 1e-149 531   57%
Product
Putative oxygenase
Gene
alpG
SAMT0159
SAMT0160
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
3uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
[pubmed all]
27
 D5MRJ1_9ACTO
(D5MRJ1)		 
[query] 33 - 493 (494)
[subject] 1 - 459 (460)
 1e-143 512   59%
Product
Putative oxygenase
Gene
hrbR
Organism
Streptomyces sp. 2238-SVT4
1uniprot[Pubmed] 20453135
Cloning and characterization of a gene cluster for hatomarubigin biosynthesis in Streptomyces sp. strain 2238-SVT4.(Appl. Environ. Microbiol.) [2010]
32
 Q6VMI4_STRAM
(Q6VMI4)		 
[query] 5 - 493 (494)
[subject] 3 - 490 (491)
 1e-138 497   55%
Product
Putative oxygenase
Gene
alpK
DSMT0188
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 14742212
Functional angucycline-like antibiotic gene cluster in the terminal inverted repeats of the Streptomyces ambofaciens linear chromosome.(Antimicrob. Agents Chemother.) [2004]
2uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
[pubmed all]
33
 Q1RQR7_STRAM
(Q1RQR7)		 
[query] 5 - 493 (494)
[subject] 3 - 490 (491)
 1e-138 497   55%
Product
Putative oxygenase
Gene
alpK
SAMT0168
SAMT0169
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
3uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
[pubmed all]
35
 Q1RQU6_STRAM
(Q1RQU6)		 
[query] 11 - 493 (494)
[subject] 6 - 484 (486)
 1e-136 489   56%
Product
Putative oxygenase
Gene
SAMT0139
SAMT0140
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
3uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
[pubmed all]
36
 Q0JWC6_STRAM
(Q0JWC6)		 
[query] 11 - 493 (494)
[subject] 6 - 484 (486)
 1e-136 488   56%
Product
Putative oxygenase
Gene
DSMT0159
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
37
 Q0JWC9_STRAM
(Q0JWC9)		 
[query] 11 - 491 (494)
[subject] 6 - 487 (504)
 1e-136 488   56%
Product
Putative oxygenase
Gene
DSMT0156
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
38
 Q1RQU9_STRAM
(Q1RQU9)		 
[query] 11 - 491 (494)
[subject] 6 - 487 (504)
 1e-135 488   56%
Product
Putative oxygenase
Gene
SAMT0136
SAMT0137
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
3uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
[pubmed all]
41
 E4NFG7_KITSK
(E4NFG7)		 
[query] 6 - 434 (494)
[subject] 1 - 431 (889)
 1e-119 433   57%
Product
Putative oxidoreductase
Gene
KSE_44640
Organism
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
1uniprot[Pubmed] 21059706
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010]
42
 C4NYK4_9ACTO
(C4NYK4)		 
[query] 10 - 491 (494)
[subject] 1 - 481 (491)
 1e-118 431   52%
Product
SaqM
Gene
saqM
Organism
Micromonospora sp. Tu 6368
1uniprot[Pubmed] 17497146
A strategy for cloning glycosyltransferase genes involved in natural product biosynthesis.(Appl. Microbiol. Biotechnol.) [2007]
2uniprot[Pubmed] 19384899
Cloning and sequencing of the biosynthetic gene cluster for saquayamycin z and galtamycin B and the elucidation of the assembly of their saccharide chains.(Chembiochem) [2009]
[pubmed all]
46
 Q6DV91_STRGL
(Q6DV91)		 
[query] 20 - 493 (494)
[subject] 20 - 493 (749)
 1e-112 412   50%
Product
Bifunctional oxygenase-reductase protein LndM2
Gene
 
Organism
Streptomyces globisporus
1uniprot[Pubmed] 15651811
Identification of the function of gene lndM2 encoding a bifunctional oxygenase-reductase involved in the biosynthesis of the antitumor antibiotic landomycin E by Streptomyces globisporus 1912 supports the originally assigned structure for landomycinone.(J. Org. Chem.) [2005]
48
 Q6DV92_STRCY
(Q6DV92)		 Jump to Lando_00080 
[query] 1 - 491 (494)
[subject] 1 - 491 (743)
 1e-111 406   48%
Product
Bifunctional oxygenase-reductase protein LanM2
Gene
 
Organism
Streptomyces cyanogenus
1uniprot[Pubmed] 15651811
Identification of the function of gene lndM2 encoding a bifunctional oxygenase-reductase involved in the biosynthesis of the antitumor antibiotic landomycin E by Streptomyces globisporus 1912 supports the originally assigned structure for landomycinone.(J. Org. Chem.) [2005]
49
 Q9ZGD2_STRCY
(Q9ZGD2)		 
[query] 1 - 491 (494)
[subject] 1 - 491 (522)
 1e-110 405   48%
Product
Oxygenase homolog
Gene
lanM
Organism
Streptomyces cyanogenus
1uniprot[Pubmed] 9933932 [Medline] 99132695
Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis.(FEMS Microbiol. Lett.) [1999]
50
 Q0RMN5_FRAAA
(Q0RMN5)		 
[query] 1 - 494 (494)
[subject] 6 - 508 (526)
 1e-110 403   49%
Product
Putative polyketide oxygenase/hydroxylase
Gene
FRAAL2565
Organism
Frankia alni (strain ACN14a)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
51
 Q93FA8_STRAT
(Q93FA8)		 
[query] 10 - 493 (494)
[subject] 8 - 491 (494)
 1e-107 393   49%
Product
Sim7
Gene
sim7
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 12115055 [Medline] 22109063
Cloning and analysis of the simocyclinone biosynthetic gene cluster of Streptomyces antibioticus Tu 6040.(Arch. Microbiol.) [2002]
52
 Q56H97_STRAU
(Q56H97)		 
[query] 1 - 493 (494)
[subject] 1 - 492 (774)
 1e-106 390   49%
Product
Aur1I
Gene
aur1I
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 12384301 [Medline] 22271582
Cloning and characterization of a polyketide synthase gene cluster involved in biosynthesis of a proposed angucycline-like polyketide auricin in Streptomyces aureofaciens CCM 3239.(Gene) [2002]
2uniprot[Pubmed] 16079347
Characterization of a regulatory gene essential for the production of the angucycline-like polyketide antibiotic auricin in Streptomyces aureofaciens CCM 3239.(Microbiology) [2005]
3uniprot[Pubmed] 20466770
The role of the TetR-family transcriptional regulator Aur1R in negative regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2010]
[pubmed all]
54
 Q0JWA6_STRAM
(Q0JWA6)		 
[query] 20 - 494 (494)
[subject] 20 - 491 (491)
 1e-103 380   48%
Product
Putative oxygenase
Gene
DSMT0180
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
55
 F2RC20_STRVP
(F2RC20)		 
[query] 5 - 491 (494)
[subject] 23 - 507 (512)
 1e-103 379   50%
Product
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Gene
SVEN_5985
Organism
Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]
56
 Q5U915_9ACTO
(Q5U915)		 Jump to Jado_00130 
[query] 5 - 491 (494)
[subject] 23 - 507 (512)
 1e-103 379   50%
Product
JadF
Gene
jadF
Organism
Streptomyces venezuelae
1uniprot[Pubmed] 15817470
Functional analyses of oxygenases in jadomycin biosynthesis and identification of JadH as a bifunctional oxygenase/dehydrase.(J. Biol. Chem.) [2005]
57
 Q6VMJ2_STRAM
(Q6VMJ2)		 
[query] 20 - 494 (494)
[subject] 20 - 491 (491)
 1e-102 378   48%
Product
Putative oxygenase
Gene
alpF
Organism
Streptomyces ambofaciens
1uniprot[Pubmed] 14742212
Functional angucycline-like antibiotic gene cluster in the terminal inverted repeats of the Streptomyces ambofaciens linear chromosome.(Antimicrob. Agents Chemother.) [2004]
58
 Q1RQS5_STRAM
(Q1RQS5)		 
[query] 20 - 494 (494)
[subject] 20 - 491 (491)
 1e-102 378   48%
Product
Putative oxygenase
Gene
alpF
SAMT0160
SAMT0161
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16952952
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
3uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
[pubmed all]
59
 D2ASL9_STRRD
(D2ASL9)		 
[query] 6 - 491 (494)
[subject] 1 - 490 (494)
 1e-101 375   48%
Product
Putative monooxygenase
Gene
Sros_5796
Organism
Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
1uniprot
Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010]
61
 Q7X2G6_9ACTO
(Q7X2G6)		 Jump to Gilvo_00160 
[query] 8 - 491 (494)
[subject] 13 - 496 (500)
 1e-101 372   45%
Product
Putative FAD-dependent oxygenase
Gene
gilOI
Organism
Streptomyces griseoflavus
1uniprot[Pubmed] 12822997 [Medline] 22708304
The complete gene cluster of the antitumor agent gilvocarcin V and its implication for the biosynthesis of the gilvocarcins.(J. Am. Chem. Soc.) [2003]
62
 Q93LX9_9ACTO
(Q93LX9)		 
[query] 20 - 490 (494)
[subject] 20 - 492 (784)
 1e-99 369   48%
Product
Oxygenase-reductase PgaM
Gene
pgaM
Organism
Streptomyces sp. PGA64
1uniprot[Pubmed] 12654660 [Medline] 22540650
Engineering anthracycline biosynthesis toward angucyclines.(Antimicrob. Agents Chemother.) [2003]
2uniprot[Pubmed] 15515887
Partial activation of a silent angucycline-type gene cluster from a rubromycin beta producing Streptomyces sp. PGA64.(J. Antibiot.) [2004]
[pubmed all]
63
 Q56156_9ACTO
(Q56156)		 
[query] 5 - 491 (494)
[subject] 23 - 520 (525)
 2e-98 364   48%
Product
C-16 hydroxylase
Gene
 
Organism
Streptomyces venezuelae
1uniprot[Pubmed] 8581159 [Medline] 96146057
Accumulation of the angucycline antibiotic rabelomycin after disruption of an oxygenase gene in the jadomycin B biosynthetic gene cluster of Streptomyces venezuelae.(Microbiology)
65
 A9FKP5_SORC5
(A9FKP5)		 
[query] 6 - 490 (494)
[subject] 1 - 502 (512)
 1e-96 358   45%
Product
Putative monooxygenase
Gene
yhjG3
sce4973
Organism
Sorangium cellulosum (strain So ce56)
Polyangium cellulosum (strain So ce56)
1uniprot[Pubmed] 17965706
Complete genome sequence of the myxobacterium Sorangium cellulosum.(Nat. Biotechnol.) [2007]
67
 Q9AMI8_STRAT
(Q9AMI8)		 
[query] 10 - 493 (494)
[subject] 8 - 491 (494)
 3e-96 357   47%
Product
Putative oxygenase SimA8
Gene
simA8
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 11959542 [Medline] 21955989
Biosynthetic gene cluster of simocyclinone, a natural multihybrid antibiotic.(Antimicrob. Agents Chemother.) [2002]
68
 Q9F6D1_9ACTO
(Q9F6D1)		 Jump to R1128_00110 
[query] 6 - 491 (494)
[subject] 1 - 492 (524)
 3e-95 353   43%
Product
Oxygenase
Gene
zhuK
Organism
Streptomyces sp. R1128
1uniprot[Pubmed] 10931852 [Medline] 20517899
Cloning, nucleotide sequence, and heterologous expression of the biosynthetic gene cluster for R1128, a non-steroidal estrogen receptor antagonist. Insights into an unusual priming mechanism.(J. Biol. Chem.) [2000]
72
 D2XDY4_9PSEU
(D2XDY4)		 
[query] 7 - 491 (494)
[subject] 3 - 448 (451)
 7e-93 346   45%
Product
AzicO5
Gene
azicO5
Organism
Kibdelosporangium sp. MJ126-NF4
1uniprot[Pubmed] 19928906
Biosynthetic studies of aziridine formation in azicemicins.(J. Am. Chem. Soc.) [2009]
73
 Q3S8P7_STRRM
(Q3S8P7)		 Jump to Oxtet_00190 
[query] 10 - 492 (494)
[subject] 5 - 500 (503)
 2e-92 345   45%
Product
OxyS
Gene
oxyS
Organism
Streptomyces rimosus
1uniprot[Pubmed] 16597959
Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase.(Appl. Environ. Microbiol.) [2006]
74
 D8I7G5_AMYMU
(D8I7G5)		 
[query] 2 - 491 (494)
[subject] 4 - 504 (514)
 4e-92 343   44%
Product
3-(3-hydroxy-phenyl)propionate hydroxylase
Gene
mhpA
AMED_5632
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
76
 Q58PK7_STRRM
(Q58PK7)		 
[query] 10 - 492 (494)
[subject] 5 - 500 (503)
 7e-91 339   45%
Product
Anhydrotetracycline oxygenase
Gene
otcC
Organism
Streptomyces rimosus
1uniprot[Pubmed] 16148009
Ablation of the otcC gene encoding a post-polyketide hydroxylase from the oxytetracyline biosynthetic pathway in Streptomyces rimosus results in novel polyketides with altered chain length.(J. Biol. Chem.) [2005]
78
 A4FIN7_SACEN
(A4FIN7)		 
[query] 8 - 494 (494)
[subject] 2 - 475 (475)
 1e-89 335   45%
Product
Monooxygenase, FAD-binding protein
Gene
SACE_4643
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
85
 F2R776_STRVP
(F2R776)		 
[query] 10 - 493 (494)
[subject] 4 - 473 (476)
 2e-87 328   45%
Product
Rifampin monooxygenase
Gene
SVEN_0481
Organism
Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]
87
 D3UA07_9ACTO
(D3UA07)		 
[query] 6 - 474 (494)
[subject] 1 - 479 (507)
 2e-87 328   44%
Product
FAD-dependent monooxygenase
Gene
 
Organism
Streptomyces flaveolus
1uniprot
Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010]
93
 Q73ZB8_MYCPA
(Q73ZB8)		 
[query] 10 - 492 (494)
[subject] 38 - 520 (525)
 1e-86 325   45%
Product
Putative uncharacterized protein
Gene
MAP_1685
Organism
Mycobacterium paratuberculosis
1uniprot[Pubmed] 16116077
The complete genome sequence of Mycobacterium avium subspecies paratuberculosis.(Proc. Natl. Acad. Sci. U.S.A.) [2005]
95
 Q8KU28_9NOCA
(Q8KU28)		 
[query] 8 - 493 (494)
[subject] 2 - 473 (475)
 1e-86 325   44%
Product
Flavin-type hydroxylase
Gene
 
Organism
Rhodococcus sp. NCIMB 9784
1uniprot[Pubmed] 12081961 [Medline] 22077259
Identification of a new class of cytochrome P450 from a Rhodococcus sp.(J. Bacteriol.) [2002]
96
 D8HR95_AMYMU
(D8HR95)		 
[query] 10 - 491 (494)
[subject] 5 - 501 (504)
 2e-86 324   43%
Product
FAD-dependent oxidoreductase
Gene
AMED_4222
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
100
 Q194P4_STRAA
(Q194P4)		 Jump to Mith_00310 
[query] 20 - 492 (494)
[subject] 25 - 507 (533)
 3e-86 323   45%
Product
Oxygenase
Gene
mtmOIV
Organism
Streptomyces argillaceus
1uniprot[Pubmed] 8654997 [Medline] 96257259
Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996]
2uniprot[Pubmed] 8757400 [Medline] 96335144
An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996]
3uniprot[Pubmed] 9150235 [Medline] 97294479
Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997]
4uniprot[Pubmed] 9733697 [Medline] 98406047
Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998]
5uniprot[Pubmed] 10102355 [Medline] 99200478
Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999]
6uniprot[Pubmed] 9889148 [Medline] 99111236
Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999]
7uniprot[Pubmed] 10660060 [Medline] 20123456
Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000]
8uniprot[Pubmed] 11254130 [Medline] 21148776
The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001]
9uniprot[Pubmed] 12733914 [Medline] 22619809
Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003]
10uniprot[Pubmed] 9917296 [Medline] 99115752
The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999]
11uniprot[Pubmed] 11853433 [Medline] 21843297
Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002]
12uniprot[Pubmed] 10652287 [Medline] 20119254
Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000]
13uniprot[Pubmed] 10779713 [Medline] 20243461
Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000]
14uniprot[Pubmed] 12022840 [Medline] 22017994
Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002]
15uniprot[Pubmed] 12813091 [Medline] 22697398
Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003]
16uniprot[Pubmed] 8807845 [Medline] 97113238
Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996]
17uniprot[Pubmed] 14660589
MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004]
18uniprot[Pubmed] 9375253 [Medline] 98042823
Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997]
19uniprot[Pubmed] 15712316
Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005]
20uniprot[Pubmed] 10760873
The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000]
21uniprot[Pubmed] 19364090
Crystal structure of Baeyer-Villiger monooxygenase MtmOIV, the key enzyme of the mithramycin biosynthetic pathway .(Biochemistry) [2009]
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