BLAST table : Pact_00100

DB	UniProtKB

	accession	Evalue	Score	Ident.	link	product	gene	organism
1	A8R0J2_9ACTO (A8R0J2)	0.0	735	100%	UniProt GenBank	Putative deacetylase Putative nucleotydyltransferase	pctI ptmG	Streptomyces pactum
2	Q9WVY1_STRLA (Q9WVY1)	3e-11	74.3	39%	UniProt GenBank	MitC Putative uncharacterized protein mitC	mitC	Streptomyces lavendulae
3	A5V0B9_ROSS1 (A5V0B9)	1e-10	72.4	33%	UniProt GenBank	LmbE family protein	RoseRS_3974	Roseiflexus sp. (strain RS-1)
4	A7NJ45_ROSCS (A7NJ45)	2e-10	72	31%	UniProt GenBank	LmbE family protein	Rcas_1416	Roseiflexus castenholzii (strain DSM 13941 / HLO8)
5	Q2IYD4_RHOP2 (Q2IYD4)	4e-10	70.9	31%	UniProt GenBank	Putative uncharacterized protein	RPB_2070	Rhodopseudomonas palustris (strain HaA2)
6	F1T7C9_9CLOT (F1T7C9)	7e-10	69.7	26%	UniProt GenBank	LmbE family protein	Cpap_3810	Clostridium papyrosolvens DSM 2782
7	Q2MEY8_STRHI (Q2MEY8)	4e-07	60.8	34%	UniProt GenBank	Putative aminoglycoside N-acetylhexosaminyl deacetylase	aprN ShinN01.1c	Streptoalloteichus hindustanus
8	Q53U10_STRFR (Q53U10)	4e-07	60.5	30%	UniProt GenBank	Nucleotidylyltransferase Putative 2-N-acetylhexosamine deacetylase, NeoD Putative uncharacterized protein	neoL neoD	Streptomyces fradiae Streptomyces roseoflavus
9	B9LJA0_CHLSY (B9LJA0)	2e-06	58.2	32%	UniProt GenBank	LmbE family protein	Chy400_2524	Chloroflexus aurantiacus (strain ATCC 29364 / DSM 637 / Y-400-fl)
10	A9WGL8_CHLAA (A9WGL8)	2e-06	58.2	32%	UniProt GenBank	LmbE family protein	Caur_2341	Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
11	D6TFE8_9CHLR (D6TFE8)	3e-06	57.8	27%	UniProt GenBank	LmbE family protein	Krac_10107	Ktedonobacter racemifer DSM 44963
12	Q1IAP0_PSEE4 (Q1IAP0)	9e-06	56.2	32%	UniProt GenBank	Putative uncharacterized protein	PSEEN2471	Pseudomonas entomophila (strain L48)
13	Q939Y6_9PSEU (Q939Y6)	1e-05	55.8	31%	UniProt GenBank	Putative uncharacterized protein		Amycolatopsis balhimycina
14	B8G6V1_CHLAD (B8G6V1)	1e-05	55.5	30%	UniProt GenBank	LmbE family protein	Cagg_3052	Chloroflexus aggregans (strain MD-66 / DSM 9485)
15	A9B5A9_HERA2 (A9B5A9)	2e-05	55.5	30%	UniProt GenBank	LmbE family protein	Haur_0082	Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785)
16	Q2MG03_MICOL (Q2MG03)	3e-05	54.7	32%	UniProt GenBank	Putative N-acetylhexosaminyl deacetylase	forD	Micromonospora olivasterospora
17	Q2MFL2_STRSD (Q2MFL2)	4e-05	53.9	31%	UniProt GenBank	Putative aminoglycoside N-acetylhexosaminyl deacetylase or alpha-ketoglutaramate amidase	aprN	Streptomyces sp. (strain ATCC 17920 / DSM 40477 / NCIB 11028) Streptomyces tenebrarius
18	Q2MFN2_STRRY (Q2MFN2)	0.0001	52.8	32%	UniProt GenBank	Putative 2-N-acetylhexosamine deacetylase	parD	Streptomyces rimosus subsp. paromomycinus
19	F8STY3_AMYOR (F8STY3)	0.0002	52	31%	UniProt GenBank	Putative uncharacterized protein		Amycolatopsis orientalis Nocardia orientalis
20	Q7WZ70_9ACTO (Q7WZ70)	0.0006	50.4	30%	UniProt GenBank	Dbv21 protein	dbv21	Nonomuraea sp. ATCC 39727

accession

alignment

Evalue

Score

Ident.

link

information

pubmed

A8R0J2_9ACTO
(A8R0J2)

0.0

735

100%

Product: Putative deacetylase
Putative nucleotydyltransferase
Gene: pctI
ptmG
Organism: Streptomyces pactum

1uniprot[Pubmed] 17827660
Cloning of the pactamycin biosynthetic gene cluster and characterization of a crucial glycosyltransferase prior to a unique cyclopentane ring formation.(J. Antibiot.) [2007]

Q9WVY1_STRLA
(Q9WVY1)

3e-11

74.3

39%

Product: MitC
Putative uncharacterized protein mitC
Gene: mitC
Organism: Streptomyces lavendulae

[pubmed all]
1uniprot[Pubmed] 10099135 [Medline] 99201491 Molecular characterization and analysis of the biosynthetic gene cluster for the antitumor antibiotic mitomycin C from Streptomyces lavendulae NRRL 2564.(Chem. Biol.) [1999]
2uniprot[Pubmed] 10094699 [Medline] 99194730 Genetic localization and molecular characterization of two key genes (mitAB) required for biosynthesis of the antitumor antibiotic mitomycin C.(J. Bacteriol.) [1999]

Q53U10_STRFR
(Q53U10)

4e-07

60.5

30%

Product: Nucleotidylyltransferase
Putative 2-N-acetylhexosamine deacetylase, NeoD
Putative uncharacterized protein
Gene: neoL
neoD
Organism: Streptomyces fradiae
Streptomyces roseoflavus

[pubmed all]
1uniprot[Pubmed] 16506694 Biosynthesis of 2-deoxystreptamine by three crucial enzymes in Streptomyces fradiae NBRC 12773.(J. Antibiot.) [2005]
2uniprot[Pubmed] 15827636 The neomycin biosynthetic gene cluster of Streptomyces fradiae NCIMB 8233: characterisation of an aminotransferase involved in the formation of 2-deoxystreptamine.(Org. Biomol. Chem.) [2005]

Q1IAP0_PSEE4
(Q1IAP0)

9e-06

56.2

32%

Product: Putative uncharacterized protein
Gene: PSEEN2471
Organism: Pseudomonas entomophila (strain L48)

1uniprot[Pubmed] 16699499
Complete genome sequence of the entomopathogenic and metabolically versatile soil bacterium Pseudomonas entomophila.(Nat. Biotechnol.) [2006]

Q939Y6_9PSEU
(Q939Y6)

1e-05

55.8

31%

Product: Putative uncharacterized protein
Gene
Organism: Amycolatopsis balhimycina

[pubmed all]
1uniprot[Pubmed] 10390204 [Medline] 99318579 Identification and analysis of the balhimycin biosynthetic gene cluster and its use for manipulating glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908.(Antimicrob. Agents Chemother.) [1999]
2uniprot[Pubmed] 11932455 [Medline] 21930292 Nonribosomal biosynthesis of vancomycin-type antibiotics: a heptapeptide backbone and eight peptide synthetase modules.(Microbiology) [2002]
3uniprot[Pubmed] 11495926 [Medline] 21486455 A polyketide synthase in glycopeptide biosynthesis: the biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine.(J. Biol. Chem.) [2001]
4uniprot[Pubmed] 12404385 The biosynthesis of vancomycin-type glycopeptide antibiotics - the order of cyclization steps.(Angew. Chem. Int. Ed. Engl.) [2001]
5uniprot[Pubmed] 11880037 [Medline] 21869276 Glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908: function of a halogenase and a haloperoxidase/perhydrolase.(Chem. Biol.) [2002]
6uniprot Precursor-directed biosynthesis for the generation of novel glycopetides.(Ernst Schering Res. Found. Workshop) [2005]

Q7WZ70_9ACTO
(Q7WZ70)

0.0006

50.4

30%

Product: Dbv21 protein
Gene: dbv21
Organism: Nonomuraea sp. ATCC 39727

[pubmed all]
1uniprot[Pubmed] 12837387 [Medline] 22721464 The gene cluster for the biosynthesis of the glycopeptide antibiotic A40926 by nonomuraea species.(Chem. Biol.) [2003]
2uniprot[Pubmed] 18559264 Crystal structures of lipoglycopeptide antibiotic deacetylases: implications for the biosynthesis of A40926 and teicoplanin.(Chem. Biol.) [2008]