BLAST table : Polk_00350

DB	UniProtKB

	accession	Evalue	Score	Ident.	link	product	gene	organism	ec
1	C0JWD0_9ACTO (C0JWD0)	0.0	992	100%	UniProt GenBank	PokL	pokL	Streptomyces diastatochromogenes
2	Q70J62_STRGR (Q70J62)	1e-125	453	53%	UniProt GenBank	Acyl CoA ligase	cmmLII	Streptomyces griseus subsp. griseus
3	D6MSV5_9ACTO (D6MSV5)	1e-116	424	48%	UniProt GenBank	SsfL2	ssfL2	Streptomyces sp. SF2575
4	D7BZR9_STRBB (D7BZR9)	1e-110	402	51%	UniProt GenBank	Acyl-CoA ligase	SBI_06854	Streptomyces bingchenggensis (strain BCW-1)
5	E8W960_STRFA (E8W960)	1e-101	374	47%	UniProt GenBank	AMP-dependent synthetase and ligase	Sfla_5326	Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
6	Q194Q9_STRAA (Q194Q9)	1e-100	369	49%	UniProt GenBank	Acyl CoA ligase	mtmL	Streptomyces argillaceus
7	D9W5B5_9ACTO (D9W5B5)	1e-90	338	46%	UniProt GenBank	Dicarboxylate-CoA ligase PimA	SSNG_07345	Streptomyces sp. C
8	D9UBL0_STRPR (D9UBL0)	2e-81	307	42%	UniProt GenBank	Putative acyl-CoA ligase	c104_04c	Streptomyces pristinaespiralis
9	Q83X39_STRRO (Q83X39)	3e-79	300	44%	UniProt GenBank	Acyl-CoA ligase	rocE	Streptomyces rochei Streptomyces parvullus
10	B5HJX7_STRPR (B5HJX7)	4e-74	283	42%	UniProt GenBank	AMP-dependent synthetase and ligase	SSDG_05474	Streptomyces pristinaespiralis ATCC 25486
11	D0MDT7_RHOM4 (D0MDT7)	2e-61	241	34%	UniProt GenBank	AMP-dependent synthetase and ligase	Rmar_2202	Rhodothermus marinus (strain ATCC 43812 / DSM 4252 / R-10) Rhodothermus obamensis
12	E4M376_9FIRM (E4M376)	9e-61	239	33%	UniProt GenBank	AMP-dependent synthetase and ligase	ThesuDRAFT_1297	Thermaerobacter subterraneus DSM 13965
13	E6SM97_THEM7 (E6SM97)	2e-60	238	33%	UniProt GenBank	AMP-dependent synthetase and ligase	Tmar_1343	Thermaerobacter marianensis (strain ATCC 700841 / DSM 12885 / JCM 10246 / 7p75a)
14	A8LLJ2_DINSH (A8LLJ2)	6e-58	229	34%	UniProt GenBank	Putative Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II	Dshi_0253	Dinoroseobacter shibae (strain DFL 12)	6.2.1.12 niceE keggE
15	D2S4Y4_GEOOG (D2S4Y4)	1e-57	229	33%	UniProt GenBank	AMP-dependent synthetase and ligase	Gobs_0293	Geodermatophilus obscurus (strain ATCC 25078 / DSM 43160 / JCM 3152 / G-20)
16	B7RX75_9GAMM (B7RX75)	1e-57	229	32%	UniProt GenBank	AMP-binding enzyme, putative	GPB2148_2158	marine gamma proteobacterium HTCC2148
17	C0STW8_9NOCA (C0STW8)	2e-57	228	36%	UniProt GenBank	Putative acyl-CoA synthetase		Rhodococcus sp. HI-31
18	Q5LVA1_SILPO (Q5LVA1)	3e-57	228	34%	UniProt GenBank	4-coumarate:CoA ligase	fadD SPO0801	Silicibacter pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)	6.2.1.12 niceE keggE
19	D1C9B6_SPHTD (D1C9B6)	5e-57	226	33%	UniProt GenBank	AMP-dependent synthetase and ligase	Sthe_3006	Sphaerobacter thermophilus (strain DSM 20745 / S 6022)
20	Q168W4_ROSDO (Q168W4)	1e-56	226	32%	UniProt GenBank	4-coumarate	RD1_1868	Roseobacter denitrificans (strain ATCC 33942 / OCh 114) Erythrobacter sp. (strain OCh 114) Roseobacter denitrificans	6.2.1.12 niceE keggE
21	4CL3_ORYSJ (Q6ETN3)	1e-56	225	34%	UniProt GenBank	Probable 4-coumarate--CoA ligase 3 4-coumaroyl-CoA synthase 3	4CL3 Os02g0177600 LOC_Os02g08100 P0504A05.24 OsJ_005431	Oryza sativa subsp. japonica Rice	6.2.1.12 niceE keggE
22	D6TJ86_9CHLR (D6TJ86)	6e-56	223	32%	UniProt GenBank	AMP-dependent synthetase and ligase	Krac_11054	Ktedonobacter racemifer DSM 44963
23	C1PCM6_BACCO (C1PCM6)	7e-56	223	32%	UniProt GenBank	AMP-dependent synthetase and ligase	BcoaDRAFT_4606	Bacillus coagulans 36D1
24	B4FQP4_MAIZE (B4FQP4)	1e-55	222	34%	UniProt GenBank	Putative uncharacterized protein		Zea mays Maize
25	Q9M7S2_LOLPR (Q9M7S2)	1e-55	222	35%	UniProt GenBank	4-coumarate--CoA ligase 4CL2		Lolium perenne Perennial ryegrass	6.2.1.12 niceE keggE
26	Q6Q297_MAIZE (Q6Q297)	1e-55	222	34%	UniProt GenBank	4-coumarate coenzyme A ligase	4CL	Zea mays Maize
27	F7ZAH5_9RHOB (F7ZAH5)	2e-55	221	31%	UniProt GenBank	4-coumarate--CoA ligase Pcl	pcl RLO149_c009640	Roseobacter litoralis Och 149	6.2.1.12 niceE keggE
28	F3ZHJ3_9ACTO (F3ZHJ3)	3e-55	221	36%	UniProt GenBank	Putative acyl-CoA synthetase, long-chain fatty acid:CoA ligase	STTU_2649	Streptomyces sp. Tu6071
29	B9T4L7_RICCO (B9T4L7)	4e-55	220	32%	UniProt GenBank	AMP dependent CoA ligase, putative	RCOM_0246200	Ricinus communis Castor bean	1.13.12.7 niceE keggE
30	B9S209_RICCO (B9S209)	4e-55	220	32%	UniProt GenBank	AMP dependent CoA ligase, putative	RCOM_1325310	Ricinus communis Castor bean	1.13.12.7 niceE keggE
31	A4IRK8_GEOTN (A4IRK8)	5e-55	220	31%	UniProt GenBank	Long-chain-fatty-acid-CoA ligase	GTNG_2617	Geobacillus thermodenitrificans (strain NG80-2)
32	B4BQH2_9BACI (B4BQH2)	5e-55	220	31%	UniProt GenBank	AMP-dependent synthetase and ligase	G11MC16DRAFT_2661	Geobacillus sp. G11MC16
33	B3R5P3_CUPTR (B3R5P3)	6e-55	220	31%	UniProt GenBank	LONG-CHAIN-FATTY-ACID--COA LIGASE PROTEIN	fadD2 RALTA_A2284	Cupriavidus taiwanensis (strain R1 / LMG 19424) Ralstonia taiwanensis (strain LMG 19424)	6.2.1.3 niceE keggE
34	D9UMH9_9ACTO (D9UMH9)	6e-55	219	35%	UniProt GenBank	Dicarboxylate-CoA ligase PimA	SSLG_03939	Streptomyces sp. SPB78
35	F2CYN7_HORVD (F2CYN7)	6e-55	219	34%	UniProt GenBank	Predicted protein		Hordeum vulgare var. distichum Two-rowed barley
36	A3V7I7_9RHOB (A3V7I7)	8e-55	219	32%	UniProt GenBank	4-coumarate:CoA ligase	SKA53_08856	Loktanella vestfoldensis SKA53
37	Q28T94_JANSC (Q28T94)	9e-55	219	34%	UniProt GenBank	AMP-dependent synthetase and ligase	Jann_1151	Jannaschia sp. (strain CCS1)
38	C9YXP0_STRSW (C9YXP0)	9e-55	219	34%	UniProt GenBank	Putative AMP-binding synthetase	fadD1 SCAB_22801	Streptomyces scabies (strain 87.22) Streptomyces scabiei
39	A0QUW5_MYCS2 (A0QUW5)	1e-54	219	33%	UniProt GenBank	4-coumarate:CoA ligase	MSMEG_2360	Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
40	O28762_ARCFU (O28762)	1e-54	219	31%	UniProt GenBank	Long-chain-fatty-acid--CoA ligase (FadD-6)	AF_1510	Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
41	C1KBY2_9CONI (C1KBY2)	2e-54	218	33%	UniProt GenBank	4-coumarate:CoA ligase	4CL1	Pinus massoniana
42	B8XCX9_9LAMI (B8XCX9)	2e-54	218	32%	UniProt GenBank	4-coumarate coenzyme A ligase	4CL	Paulownia fortunei
43	Q1LK14_RALME (Q1LK14)	2e-54	218	30%	UniProt GenBank	Long-chain-fatty-acid-CoA ligase (Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II)	fadD Rmet_2635	Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839)	6.2.1.3 niceE keggE
44	Q9M7S3_LOLPR (Q9M7S3)	3e-54	218	33%	UniProt GenBank	4-coumarate--CoA ligase 4CL1		Lolium perenne Perennial ryegrass	6.2.1.12 niceE keggE
45	B7SBA5_9BRYO (B7SBA5)	3e-54	218	32%	UniProt GenBank	4-coumarate:coenzyme A ligase 3	4CL3	Ephemerella readeri	6.2.1.12 niceE keggE
46	A9SET7_PHYPA (A9SET7)	3e-54	217	31%	UniProt GenBank	Predicted protein	PHYPADRAFT_233094	Physcomitrella patens subsp. patens Moss
47	A2YFS4_ORYSI (A2YFS4)	3e-54	217	34%	UniProt GenBank	Putative uncharacterized protein	OsI_23962	Oryza sativa subsp. indica Rice
48	C5Y0F9_SORBI (C5Y0F9)	4e-54	217	33%	UniProt GenBank	Putative uncharacterized protein Sb04g031010	Sb04g031010 SORBIDRAFT_04g031010	Sorghum bicolor Sorghum Sorghum vulgare
49	B7SBA1_PHYPA (B7SBA1)	4e-54	217	32%	UniProt GenBank	4-coumarate:coenzyme A ligase 3	4CL3	Physcomitrella patens subsp. patens Moss	6.2.1.12 niceE keggE
50	D3PSC1_MEIRD (D3PSC1)	5e-54	217	31%	UniProt GenBank	AMP-dependent synthetase and ligase	Mrub_1592	Meiothermus ruber (strain ATCC 35948 / DSM 1279 / VKM B-1258 / 21) Thermus ruber
51	B7EFQ0_ORYSJ (B7EFQ0)	5e-54	217	34%	UniProt GenBank	cDNA clone:J023002B16, full insert sequence		Oryza sativa subsp. japonica Rice
52	4CL4_ORYSJ (Q67W82)	5e-54	217	34%	UniProt GenBank	Probable 4-coumarate--CoA ligase 4 4-coumaroyl-CoA synthase 4	4CL4 Os06g0656500 LOC_Os06g44620 P0460H04.31-1 P0460H04.31-2	Oryza sativa subsp. japonica Rice	6.2.1.12 niceE keggE
53	B2HHC5_MYCMM (B2HHC5)	7e-54	216	34%	UniProt GenBank	Fatty-acid-CoA ligase	MMAR_1606	Mycobacterium marinum (strain ATCC BAA-535 / M)
54	E7QRP2_9EURY (E7QRP2)	9e-54	216	33%	UniProt GenBank	AMP-dependent synthetase and ligase	ZOD2009_07324	Haladaptatus paucihalophilus DX253
55	C6WPK0_ACTMD (C6WPK0)	1e-53	216	33%	UniProt GenBank	AMP-dependent synthetase and ligase	Amir_6754	Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
56	O81140_POPTM (O81140)	1e-53	216	32%	UniProt GenBank	4-coumarate:CoA ligase		Populus tremuloides Quaking aspen	6.2.1.12 niceE keggE
57	Q0K7Z8_CUPNH (Q0K7Z8)	1e-53	216	30%	UniProt GenBank	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	H16_A2794	Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) Ralstonia eutropha	6.2.1.- niceE keggE
58	D6M6E4_9ACTO (D6M6E4)	1e-53	215	35%	UniProt GenBank	Long-chain-fatty-acid-CoA ligase	SSBG_05598	Streptomyces sp. SPB74
59	B6RIV5_RUTGR (B6RIV5)	1e-53	215	31%	UniProt GenBank	4-coumarate:CoA ligase 2		Ruta graveolens Common rue
60	B3TJI5_RUTGR (B3TJI5)	1e-53	215	31%	UniProt GenBank	4-coumarate CoA ligase 2		Ruta graveolens Common rue
61	D7D0X2_GEOSC (D7D0X2)	1e-53	215	31%	UniProt GenBank	AMP-dependent synthetase and ligase	GC56T3_2542	Geobacillus sp. (strain C56-T3)
62	E4W6N2_GOSHI (E4W6N2)	1e-53	215	33%	UniProt GenBank	4-coumarate:CoA ligase 2	4CL2	Gossypium hirsutum Upland cotton Gossypium mexicanum
63	B7SBA9_9BRYO (B7SBA9)	1e-53	215	32%	UniProt GenBank	4-coumarate:coenzyme A ligase 3	4CL3	Physcomitrella patens subsp. magdalenae	6.2.1.12 niceE keggE
64	E2MXH7_9CORY (E2MXH7)	2e-53	215	33%	UniProt GenBank	4-coumarate--CoA ligase 3	CORAM0001_1200	Corynebacterium amycolatum SK46	6.2.1.12 niceE keggE
65	C5XW95_SORBI (C5XW95)	2e-53	215	34%	UniProt GenBank	Putative uncharacterized protein Sb04g005210	Sb04g005210 SORBIDRAFT_04g005210	Sorghum bicolor Sorghum Sorghum vulgare
66	B8QN50_PINRA (B8QN50)	2e-53	215	33%	UniProt GenBank	4-coumarate-CoA ligase		Pinus radiata Monterey pine Pinus insignis
67	E6N957_9ARCH (E6N957)	2e-53	215	32%	UniProt GenBank	Long-chain-fatty-acid--CoA ligase	CSUB_C1648 HGMM_F09F01C14 HGMM_F52D03C07	Candidatus Caldiarchaeum subterraneum	6.2.1.3 niceE keggE
68	B7SBB0_9BRYO (B7SBB0)	2e-53	214	33%	UniProt GenBank	4-coumarate:coenzyme A ligase 4	4CL4	Physcomitrella patens subsp. magdalenae	6.2.1.12 niceE keggE
69	B7RHP2_9RHOB (B7RHP2)	2e-53	214	31%	UniProt GenBank	Long-chain-fatty-acid--CoA ligase	lcfA RGAI101_1658	Roseobacter sp. GAI101	6.2.1.3 niceE keggE
70	4CL_PINTA (P41636)	2e-53	214	32%	UniProt GenBank	4-coumarate--CoA ligase 4-coumaroyl-CoA synthase	4CL	Pinus taeda Loblolly pine	6.2.1.12 niceE keggE
71	B7SBA0_PHYPA (B7SBA0)	3e-53	214	33%	UniProt GenBank	4-coumarate:coenzyme A ligase 2	4CL2	Physcomitrella patens subsp. patens Moss	6.2.1.12 niceE keggE
72	B8LQR8_PICSI (B8LQR8)	3e-53	214	31%	UniProt GenBank	Putative uncharacterized protein		Picea sitchensis Sitka spruce Pinus sitchensis
73	B3S1X1_TRIAD (B3S1X1)	3e-53	214	29%	UniProt GenBank	Putative uncharacterized protein	TRIADDRAFT_27462	Trichoplax adhaerens Trichoplax reptans
74	E5WM79_9BACI (E5WM79)	4e-53	214	29%	UniProt GenBank	Long-chain fatty-acid-CoA ligase	HMPREF1013_03564	Bacillus sp. 2_A_57_CT2
75	A9RP51_PHYPA (A9RP51)	4e-53	213	33%	UniProt GenBank	Predicted protein	PHYPADRAFT_104959	Physcomitrella patens subsp. patens Moss
76	Q67G17_SALMI (Q67G17)	5e-53	213	32%	UniProt GenBank	4-coumarate:coenzyme A ligase 2		Salvia miltiorrhiza Chinese sage
77	A9T8V9_PHYPA (A9T8V9)	5e-53	213	33%	UniProt GenBank	Predicted protein	PHYPADRAFT_89614	Physcomitrella patens subsp. patens Moss
78	E6S6K9_INTC7 (E6S6K9)	5e-53	213	31%	UniProt GenBank	AMP-dependent synthetase and ligase	Intca_3553	Intrasporangium calvum (strain ATCC 23552 / DSM 43043 / JCM 3097 / NBRC 12989 / 7 KIP)
79	D7CTE8_TRURR (D7CTE8)	6e-53	213	33%	UniProt GenBank	AMP-dependent synthetase and ligase	Trad_0669	Truepera radiovictrix (strain DSM 17093 / CIP 108686 / LMG 22925 / RQ-24)
80	E8SXR6_GEOS2 (E8SXR6)	6e-53	213	31%	UniProt GenBank	AMP-dependent synthetase and ligase	GYMC52_0930	Geobacillus sp. (strain Y412MC52)
81	C9RYX7_GEOSY (C9RYX7)	6e-53	213	31%	UniProt GenBank	AMP-dependent synthetase and ligase	GYMC61_1803	Geobacillus sp. (strain Y412MC61)
82	B7SB99_PHYPA (B7SB99)	6e-53	213	33%	UniProt GenBank	4-coumarate:coenzyme A ligase 1	4CL1	Physcomitrella patens subsp. patens Moss	6.2.1.12 niceE keggE
83	B7SBA8_9BRYO (B7SBA8)	6e-53	213	32%	UniProt GenBank	4-coumarate:coenzyme A ligase 2	4CL2	Physcomitrella patens subsp. magdalenae	6.2.1.12 niceE keggE
84	B7SBA7_9BRYO (B7SBA7)	6e-53	213	33%	UniProt GenBank	4-coumarate:coenzyme A ligase 1	4CL1	Physcomitrella patens subsp. magdalenae	6.2.1.12 niceE keggE
85	Q3ABD3_CARHZ (Q3ABD3)	6e-53	213	30%	UniProt GenBank	Long-chain-fatty-acid--CoA ligase	fadD3 CHY_1731	Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008)	6.2.1.3 niceE keggE
86	Q3M5Z4_ANAVT (Q3M5Z4)	7e-53	213	30%	UniProt GenBank	AMP-dependent synthetase and ligase	Ava_3987	Anabaena variabilis (strain ATCC 29413 / PCC 7937)	6.2.1.26 niceE keggE
87	D8RPI3_SELML (D8RPI3)	8e-53	213	35%	UniProt GenBank	Putative uncharacterized protein	SELMODRAFT_232017	Selaginella moellendorffii Spikemoss
88	4CL3_ARATH (Q9S777)	8e-53	213	32%	UniProt GenBank	4-coumarate--CoA ligase 3 4-coumarate--CoA ligase isoform 3 4-coumarate--CoA ligase isoform 3 4-coumaroyl-CoA synthase 3	4CL3 At1g65060 F16G16.6	Arabidopsis thaliana Mouse-ear cress	6.2.1.12 niceE keggE
89	A4J8R3_DESRM (A4J8R3)	8e-53	213	30%	UniProt GenBank	AMP-dependent synthetase and ligase	Dred_2963	Desulfotomaculum reducens (strain MI-1)
90	Q474I1_CUPPJ (Q474I1)	9e-53	213	30%	UniProt GenBank	AMP-dependent synthetase and ligase	Reut_A0823	Cupriavidus pinatubonensis (strain JMP134 / LMG 1197) Alcaligenes eutrophus Ralstonia eutropha
91	A4EER6_9RHOB (A4EER6)	9e-53	213	32%	UniProt GenBank	4-coumarate:CoA ligase	RCCS2_05864	Roseobacter sp. CCS2
92	A9PGE3_POPTR (A9PGE3)	9e-53	213	32%	UniProt GenBank	4-Coumarate:CoA ligase Putative uncharacterized protein	Ptr4CL4 POPTRDRAFT_665396	Populus trichocarpa Western balsam poplar Populus balsamifera subsp. trichocarpa
93	B3TNC2_9POAL (B3TNC2)	1e-52	212	34%	UniProt GenBank	4-coumarate:CoA ligase		Neosinocalamus affinis
94	E5W595_9BACI (E5W595)	1e-52	212	30%	UniProt GenBank	YhfL protein	HMPREF1012_01967	Bacillus sp. BT1B_CT2
95	E4W5X7_GOSHI (E4W5X7)	1e-52	212	33%	UniProt GenBank	4-coumarate:CoA ligase 1	4CL1	Gossypium hirsutum Upland cotton Gossypium mexicanum
96	Q9HQ43_HALSA (Q9HQ43)	1e-52	212	33%	UniProt GenBank	Putative uncharacterized protein	VNG_1339C	Halobacterium salinarium (strain ATCC 700922 / JCM 11081 / NRC-1) Halobacterium halobium
97	B0R5D9_HALS3 (B0R5D9)	1e-52	212	33%	UniProt GenBank	Acyl-CoA synthetase	acs3 OE2912F	Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)	6.2.1.- niceE keggE
98	F5BYB1_9POAL (F5BYB1)	1e-52	212	33%	UniProt GenBank	4-coumarate: coenzyme A ligase	4CL2	Panicum virgatum (switchgrass)
99	B9UCK0_9POAL (B9UCK0)	1e-52	212	33%	UniProt GenBank	4-coumarate coenzyme A ligase 1	4CL1	Panicum virgatum (switchgrass)	6.2.1.12 niceE keggE
100	B7SBA4_9BRYO (B7SBA4)	1e-52	212	32%	UniProt GenBank	4-coumarate:coenzyme A ligase 2	4CL2	Ephemerella readeri	6.2.1.12 niceE keggE

accession

alignment

Evalue

Score

Ident.

link

information

pubmed

C0JWD0_9ACTO
(C0JWD0)

0.0

992

100%

Product: PokL
Gene: pokL
Organism: Streptomyces diastatochromogenes

1uniprot[Pubmed] 19266534
Organisation of the Biosynthetic Gene Cluster and Tailoring Enzymes in the Biosynthesis of the Tetracyclic Quinone Glycoside Antibiotic Polyketomycin.(Chembiochem) [2009]

D6MSV5_9ACTO
(D6MSV5)

1e-116

424

48%

Product: SsfL2
Gene: ssfL2
Organism: Streptomyces sp. SF2575

1uniprot[Pubmed] 19908837
Biochemical analysis of the biosynthetic pathway of an anticancer tetracycline SF2575.(J. Am. Chem. Soc.) [2009]

D7BZR9_STRBB
(D7BZR9)

1e-110

402

51%

Product: Acyl-CoA ligase
Gene: SBI_06854
Organism: Streptomyces bingchenggensis (strain BCW-1)

1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]

Q194Q9_STRAA
(Q194Q9)

1e-100

369

49%

Product: Acyl CoA ligase
Gene: mtmL
Organism: Streptomyces argillaceus

[pubmed all]
1uniprot[Pubmed] 8654997 [Medline] 96257259 Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996]
2uniprot[Pubmed] 8757400 [Medline] 96335144 An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996]
3uniprot[Pubmed] 9150235 [Medline] 97294479 Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997]
4uniprot[Pubmed] 9733697 [Medline] 98406047 Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998]
5uniprot[Pubmed] 10102355 [Medline] 99200478 Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999]
6uniprot[Pubmed] 9889148 [Medline] 99111236 Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999]
7uniprot[Pubmed] 10660060 [Medline] 20123456 Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000]
8uniprot[Pubmed] 11254130 [Medline] 21148776 The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001]
9uniprot[Pubmed] 12733914 [Medline] 22619809 Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003]
10uniprot[Pubmed] 9917296 [Medline] 99115752 The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999]
11uniprot[Pubmed] 11853433 [Medline] 21843297 Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002]
12uniprot[Pubmed] 10652287 [Medline] 20119254 Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000]
13uniprot[Pubmed] 10779713 [Medline] 20243461 Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000]
14uniprot[Pubmed] 12022840 [Medline] 22017994 Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002]
15uniprot[Pubmed] 12813091 [Medline] 22697398 Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003]
16uniprot[Pubmed] 8807845 [Medline] 97113238 Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996]
17uniprot[Pubmed] 14660589 MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004]
18uniprot[Pubmed] 9375253 [Medline] 98042823 Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997]
19uniprot[Pubmed] 15712316 Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005]
20uniprot[Pubmed] 10760873 The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000]

D9UBL0_STRPR
(D9UBL0)

2e-81

307

42%

Product: Putative acyl-CoA ligase
Gene: c104_04c
Organism: Streptomyces pristinaespiralis

1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]

Q83X39_STRRO
(Q83X39)

3e-79

300

44%

Product: Acyl-CoA ligase
Gene: rocE
Organism: Streptomyces rochei
Streptomyces parvullus

[pubmed all]
1uniprot[Pubmed] 12791134 [Medline] 22676866 The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175 Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737 Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144 Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]

D0MDT7_RHOM4
(D0MDT7)

2e-61

241

34%

Product: AMP-dependent synthetase and ligase
Gene: Rmar_2202
Organism: Rhodothermus marinus (strain ATCC 43812 / DSM 4252 / R-10)
Rhodothermus obamensis

1uniprot
Complete genome sequence of Rhodothermus marinus type strain (R-10T).(Stand. Genomic Sci.) [2009]

E6SM97_THEM7
(E6SM97)

2e-60

238

33%

Product: AMP-dependent synthetase and ligase
Gene: Tmar_1343
Organism: Thermaerobacter marianensis (strain ATCC 700841 / DSM 12885 / JCM 10246 / 7p75a)

1uniprot
Complete genome sequence of Thermaerobacter marianensis type strain (7p75aT).(Stand. Genomic Sci.) [2010]

C0STW8_9NOCA
(C0STW8)

2e-57

228

36%

Product: Putative acyl-CoA synthetase
Gene
Organism: Rhodococcus sp. HI-31

1uniprot
Crystal structures of cyclohexanone monooxygenase reveal complex domain movements and a sliding cofactor.(J. Am. Chem. Soc.) [2009]

Q5LVA1_SILPO
(Q5LVA1)

3e-57

228

34%

Product: 4-coumarate:CoA ligase
Gene: fadD
SPO0801
Organism: Silicibacter pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)

1uniprot[Pubmed] 15602564
Genome sequence of Silicibacter pomeroyi reveals adaptations to the marine environment.(Nature) [2004]

Q168W4_ROSDO
(Q168W4)

1e-56

226

32%

Product: 4-coumarate
Gene: RD1_1868
Organism: Roseobacter denitrificans (strain ATCC 33942 / OCh 114)
Erythrobacter sp. (strain OCh 114)
Roseobacter denitrificans

1uniprot[Pubmed] 17098896
The complete genome sequence of Roseobacter denitrificans reveals a mixotrophic rather than photosynthetic metabolism.(J. Bacteriol.) [2007]

4CL3_ORYSJ
(Q6ETN3)

1e-56

225

34%

Product: Probable 4-coumarate--CoA ligase 3
4-coumaroyl-CoA synthase 3
Gene: 4CL3
Os02g0177600
LOC_Os02g08100
P0504A05.24
OsJ_005431
Organism: Oryza sativa subsp. japonica
Rice

[pubmed all]
1uniprot[Pubmed] 16100779 The map-based sequence of the rice genome.(Nature) [2005]
2uniprot[Pubmed] 18089549 The rice annotation project database (RAP-DB): 2008 update.(Nucleic Acids Res.) [2008]
3uniprot[Pubmed] 15685292 The genomes of Oryza sativa: a history of duplications.(PLoS Biol.) [2005]
4uniprot[Pubmed] 18627494 Genome-wide analysis of a land plant-specific acyl:coenzyme A synthetase (ACS) gene family in Arabidopsis, poplar, rice and Physcomitrella.(New Phytol.) [2008]

F7ZAH5_9RHOB
(F7ZAH5)

2e-55

221

31%

Product: 4-coumarate--CoA ligase Pcl
Gene: pcl
RLO149_c009640
Organism: Roseobacter litoralis Och 149

1uniprot[Pubmed] 21693016
Comparative genome analysis and genome-guided physiological analysis of Roseobacter litoralis.(BMC Genomics) [2011]

A4IRK8_GEOTN
(A4IRK8)

5e-55

220

31%

Product: Long-chain-fatty-acid-CoA ligase
Gene: GTNG_2617
Organism: Geobacillus thermodenitrificans (strain NG80-2)

1uniprot[Pubmed] 17372208
Genome and proteome of long-chain alkane degrading Geobacillus thermodenitrificans NG80-2 isolated from a deep-subsurface oil reservoir.(Proc. Natl. Acad. Sci. U.S.A.) [2007]

B3R5P3_CUPTR
(B3R5P3)

6e-55

220

31%

Product: LONG-CHAIN-FATTY-ACID--COA LIGASE PROTEIN
Gene: fadD2
RALTA_A2284
Organism: Cupriavidus taiwanensis (strain R1 / LMG 19424)
Ralstonia taiwanensis (strain LMG 19424)

1uniprot[Pubmed] 18490699
Genome sequence of the beta-rhizobium Cupriavidus taiwanensis and comparative genomics of rhizobia.(Genome Res.) [2008]

F2CYN7_HORVD
(F2CYN7)

6e-55

219

34%

Product: Predicted protein
Gene
Organism: Hordeum vulgare var. distichum
Two-rowed barley

1uniprot[Pubmed] 21415278
Comprehensive Sequence Analysis of 24,783 Barley Full-Length cDNAs Derived from 12 Clone Libraries.(Plant Physiol.) [2011]

C9YXP0_STRSW
(C9YXP0)

9e-55

219

34%

Product: Putative AMP-binding synthetase
Gene: fadD1
SCAB_22801
Organism: Streptomyces scabies (strain 87.22)
Streptomyces scabiei

1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]

O28762_ARCFU
(O28762)

1e-54

219

31%

Product: Long-chain-fatty-acid--CoA ligase (FadD-6)
Gene: AF_1510
Organism: Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)

1uniprot[Pubmed] 9389475 [Medline] 98049343
The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus.(Nature) [1997]

B7SBA5_9BRYO
(B7SBA5)

3e-54

218

32%

Product: 4-coumarate:coenzyme A ligase 3
Gene: 4CL3
Organism: Ephemerella readeri

1uniprot[Pubmed] 18722632
Identification of a 4-coumarate:CoA ligase gene family in the moss, Physcomitrella patens.(Phytochemistry) [2008]

A9SET7_PHYPA
(A9SET7)

3e-54

217

31%

Product: Predicted protein
Gene: PHYPADRAFT_233094
Organism: Physcomitrella patens subsp. patens
Moss

1uniprot[Pubmed] 18079367
The Physcomitrella genome reveals evolutionary insights into the conquest of land by plants.(Science) [2008]

A2YFS4_ORYSI
(A2YFS4)

3e-54

217

34%

Product: Putative uncharacterized protein
Gene: OsI_23962
Organism: Oryza sativa subsp. indica
Rice

1uniprot[Pubmed] 15685292
The genomes of Oryza sativa: a history of duplications.(PLoS Biol.) [2005]

C5Y0F9_SORBI
(C5Y0F9)

4e-54

217

33%

Product: Putative uncharacterized protein Sb04g031010
Gene: Sb04g031010
SORBIDRAFT_04g031010
Organism: Sorghum bicolor
Sorghum
Sorghum vulgare

1uniprot[Pubmed] 19189423
The Sorghum bicolor genome and the diversification of grasses.(Nature) [2009]

B7SBA1_PHYPA
(B7SBA1)

4e-54

217

32%

Product: 4-coumarate:coenzyme A ligase 3
Gene: 4CL3
Organism: Physcomitrella patens subsp. patens
Moss

1uniprot[Pubmed] 18722632
Identification of a 4-coumarate:CoA ligase gene family in the moss, Physcomitrella patens.(Phytochemistry) [2008]

D3PSC1_MEIRD
(D3PSC1)

5e-54

217

31%

Product: AMP-dependent synthetase and ligase
Gene: Mrub_1592
Organism: Meiothermus ruber (strain ATCC 35948 / DSM 1279 / VKM B-1258 / 21)
Thermus ruber

1uniprot
Complete genome sequence of Meiothermus ruber type strain (21T).(Stand. Genomic Sci.) [2010]

B7EFQ0_ORYSJ
(B7EFQ0)

5e-54

217

34%

Product: cDNA clone:J023002B16, full insert sequence
Gene
Organism: Oryza sativa subsp. japonica
Rice

1uniprot
Collection, Mapping, and Annotation of Over 28,000 cDNA Clones from japonica Rice.(Science) [2003]

4CL4_ORYSJ
(Q67W82)

5e-54

217

34%

Product: Probable 4-coumarate--CoA ligase 4
4-coumaroyl-CoA synthase 4
Gene: 4CL4
Os06g0656500
LOC_Os06g44620
P0460H04.31-1
P0460H04.31-2
Organism: Oryza sativa subsp. japonica
Rice

[pubmed all]
1uniprot[Pubmed] 16100779 The map-based sequence of the rice genome.(Nature) [2005]
2uniprot[Pubmed] 18089549 The rice annotation project database (RAP-DB): 2008 update.(Nucleic Acids Res.) [2008]
3uniprot[Pubmed] 12869764 [Medline] 22752273 Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice.(Science) [2003]
4uniprot[Pubmed] 18627494 Genome-wide analysis of a land plant-specific acyl:coenzyme A synthetase (ACS) gene family in Arabidopsis, poplar, rice and Physcomitrella.(New Phytol.) [2008]

B2HHC5_MYCMM
(B2HHC5)

7e-54

216

34%

Product: Fatty-acid-CoA ligase
Gene: MMAR_1606
Organism: Mycobacterium marinum (strain ATCC BAA-535 / M)

1uniprot[Pubmed] 18403782
Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis.(Genome Res.) [2008]

C6WPK0_ACTMD
(C6WPK0)

1e-53

216

33%

Product: AMP-dependent synthetase and ligase
Gene: Amir_6754
Organism: Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)

1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]

O81140_POPTM
(O81140)

1e-53

216

32%

Product: 4-coumarate:CoA ligase
Gene
Organism: Populus tremuloides
Quaking aspen

1uniprot[Pubmed] 9560289 [Medline] 98226828
Compartmentalized expression of two structurally and functionally distinct 4-coumarate:CoA ligase genes in aspen (Populus tremuloides).(Proc. Natl. Acad. Sci. U.S.A.) [1998]

Q0K7Z8_CUPNH
(Q0K7Z8)

1e-53

216

30%

Product: Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II
Gene: H16_A2794
Organism: Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)
Ralstonia eutropha

1uniprot[Pubmed] 16964242
Genome sequence of the bioplastic-producing 'Knallgas' bacterium Ralstonia eutropha H16.(Nat. Biotechnol.) [2006]

B3TJI5_RUTGR
(B3TJI5)

1e-53

215

31%

Product: 4-coumarate CoA ligase 2
Gene
Organism: Ruta graveolens
Common rue

1uniprot[Pubmed] 18379886
Unusually divergent 4-coumarate:CoA-ligases from Ruta graveolens L.(Plant Mol. Biol.) [2008]

B7SBA9_9BRYO
(B7SBA9)

1e-53

215

32%

Product: 4-coumarate:coenzyme A ligase 3
Gene: 4CL3
Organism: Physcomitrella patens subsp. magdalenae

1uniprot[Pubmed] 18722632
Identification of a 4-coumarate:CoA ligase gene family in the moss, Physcomitrella patens.(Phytochemistry) [2008]

C5XW95_SORBI
(C5XW95)

2e-53

215

34%

Product: Putative uncharacterized protein Sb04g005210
Gene: Sb04g005210
SORBIDRAFT_04g005210
Organism: Sorghum bicolor
Sorghum
Sorghum vulgare

1uniprot[Pubmed] 19189423
The Sorghum bicolor genome and the diversification of grasses.(Nature) [2009]

B8QN50_PINRA
(B8QN50)

2e-53

215

33%

Product: 4-coumarate-CoA ligase
Gene
Organism: Pinus radiata
Monterey pine
Pinus insignis

1uniprot[Pubmed] 18971431
Suppression of 4-coumarate-CoA ligase in the coniferous gymnosperm Pinus radiata.(Plant Physiol.) [2009]

E6N957_9ARCH
(E6N957)

2e-53

215

32%

Product: Long-chain-fatty-acid--CoA ligase
Gene: CSUB_C1648
HGMM_F09F01C14
HGMM_F52D03C07
Organism: Candidatus Caldiarchaeum subterraneum

1uniprot
Genetic and functional properties of uncultivated thermophilic crenarchaeotes from a subsurface gold mine as revealed by analysis of genome fragments.(Environ. Microbiol.) [2005]

2uniprot
Insights into the evolution of Archaea and eukaryotic protein modifier systems revealed by the genome of a novel archaeal group.(Nucleic Acids Res.) [2010]

B7SBB0_9BRYO
(B7SBB0)

2e-53

214

33%

Product: 4-coumarate:coenzyme A ligase 4
Gene: 4CL4
Organism: Physcomitrella patens subsp. magdalenae

1uniprot[Pubmed] 18722632
Identification of a 4-coumarate:CoA ligase gene family in the moss, Physcomitrella patens.(Phytochemistry) [2008]

4CL_PINTA
(P41636)

2e-53

214

32%

Product: 4-coumarate--CoA ligase
4-coumaroyl-CoA synthase
Gene: 4CL
Organism: Pinus taeda
Loblolly pine

1uniprot[Pubmed] 9008388 [Medline] 97161117
Molecular cloning of 4-coumarate:coenzyme A ligase in loblolly pine and the roles of this enzyme in the biosynthesis of lignin in compression wood.(Plant Physiol.) [1997]

B7SBA0_PHYPA
(B7SBA0)

3e-53

214

33%

Product: 4-coumarate:coenzyme A ligase 2
Gene: 4CL2
Organism: Physcomitrella patens subsp. patens
Moss

1uniprot[Pubmed] 18722632
Identification of a 4-coumarate:CoA ligase gene family in the moss, Physcomitrella patens.(Phytochemistry) [2008]

B3S1X1_TRIAD
(B3S1X1)

3e-53

214

29%

Product: Putative uncharacterized protein
Gene: TRIADDRAFT_27462
Organism: Trichoplax adhaerens
Trichoplax reptans

1uniprot[Pubmed] 18719581
The Trichoplax genome and the nature of placozoans.(Nature) [2008]

A9RP51_PHYPA
(A9RP51)

4e-53

213

33%

Product: Predicted protein
Gene: PHYPADRAFT_104959
Organism: Physcomitrella patens subsp. patens
Moss

1uniprot[Pubmed] 18079367
The Physcomitrella genome reveals evolutionary insights into the conquest of land by plants.(Science) [2008]

Q67G17_SALMI
(Q67G17)

5e-53

213

32%

Product: 4-coumarate:coenzyme A ligase 2
Gene
Organism: Salvia miltiorrhiza
Chinese sage

1uniprot
Two Divergent Members of 4-Coumarate: Coenzyme A Ligase from Salvia miltiorrhiza Bunge: cDNA Cloning and Functional Study.(J. Integr. Plant Biol.) [2006]

A9T8V9_PHYPA
(A9T8V9)

5e-53

213

33%

Product: Predicted protein
Gene: PHYPADRAFT_89614
Organism: Physcomitrella patens subsp. patens
Moss

1uniprot[Pubmed] 18079367
The Physcomitrella genome reveals evolutionary insights into the conquest of land by plants.(Science) [2008]

E6S6K9_INTC7
(E6S6K9)

5e-53

213

31%

Product: AMP-dependent synthetase and ligase
Gene: Intca_3553
Organism: Intrasporangium calvum (strain ATCC 23552 / DSM 43043 / JCM 3097 / NBRC 12989 / 7 KIP)

1uniprot[Pubmed] 21304734
Complete genome sequence of Intrasporangium calvum type strain (7 KIP).(Stand. Genomic Sci.) [2010]

B7SB99_PHYPA
(B7SB99)

6e-53

213

33%

Product: 4-coumarate:coenzyme A ligase 1
Gene: 4CL1
Organism: Physcomitrella patens subsp. patens
Moss

1uniprot[Pubmed] 18722632
Identification of a 4-coumarate:CoA ligase gene family in the moss, Physcomitrella patens.(Phytochemistry) [2008]

B7SBA8_9BRYO
(B7SBA8)

6e-53

213

32%

Product: 4-coumarate:coenzyme A ligase 2
Gene: 4CL2
Organism: Physcomitrella patens subsp. magdalenae

1uniprot[Pubmed] 18722632
Identification of a 4-coumarate:CoA ligase gene family in the moss, Physcomitrella patens.(Phytochemistry) [2008]

B7SBA7_9BRYO
(B7SBA7)

6e-53

213

33%

Product: 4-coumarate:coenzyme A ligase 1
Gene: 4CL1
Organism: Physcomitrella patens subsp. magdalenae

1uniprot[Pubmed] 18722632
Identification of a 4-coumarate:CoA ligase gene family in the moss, Physcomitrella patens.(Phytochemistry) [2008]

Q3ABD3_CARHZ
(Q3ABD3)

6e-53

213

30%

Product: Long-chain-fatty-acid--CoA ligase
Gene: fadD3
CHY_1731
Organism: Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008)

1uniprot[Pubmed] 16311624
Life in hot carbon monoxide: the complete genome sequence of Carboxydothermus hydrogenoformans Z-2901.(PLoS Genet.) [2005]

D8RPI3_SELML
(D8RPI3)

8e-53

213

35%

Product: Putative uncharacterized protein
Gene: SELMODRAFT_232017
Organism: Selaginella moellendorffii
Spikemoss

1uniprot[Pubmed] 21551031
The Selaginella genome identifies genetic changes associated with the evolution of vascular plants.(Science) [2011]

4CL3_ARATH
(Q9S777)

8e-53

213

32%

Product: 4-coumarate--CoA ligase 3
4-coumarate--CoA ligase isoform 3
4-coumarate--CoA ligase isoform 3
4-coumaroyl-CoA synthase 3
Gene: 4CL3
At1g65060
F16G16.6
Organism: Arabidopsis thaliana
Mouse-ear cress

[pubmed all]
1uniprot[Pubmed] 10417722 [Medline] 99348176 Three 4-coumarate:coenzyme A ligases in Arabidopsis thaliana represent two evolutionarily divergent classes in angiosperms.(Plant J.) [1999]
2uniprot[Pubmed] 11130712 [Medline] 21016719 Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.(Nature) [2000]
3uniprot[Pubmed] 14593172 [Medline] 22954850 Empirical analysis of transcriptional activity in the Arabidopsis genome.(Science) [2003]
4uniprot[Pubmed] 12805634 [Medline] 22690213 Arabidopsis contains a large superfamily of acyl-activating enzymes. Phylogenetic and biochemical analysis reveals a new class of acyl-coenzyme a synthetases.(Plant Physiol.) [2003]
5uniprot[Pubmed] 12819348 The substrate specificity-determining amino acid code of 4-coumarate:CoA ligase.(Proc. Natl. Acad. Sci. U.S.A.) [2003]

A9PGE3_POPTR
(A9PGE3)

9e-53

213

32%

Product: 4-Coumarate:CoA ligase
Putative uncharacterized protein
Gene: Ptr4CL4
POPTRDRAFT_665396
Organism: Populus trichocarpa
Western balsam poplar
Populus balsamifera subsp. trichocarpa

[pubmed all]
1uniprot[Pubmed] 18230180 Analysis of 4,664 high-quality sequence-finished poplar full-length cDNA clones and their utility for the discovery of genes responding to insect feeding.(BMC Genomics) [2008]
2uniprot[Pubmed] 16973872 The genome of black cottonwood, Populus trichocarpa (Torr. & Gray).(Science) [2006]

Q9HQ43_HALSA
(Q9HQ43)

1e-52

212

33%

Product: Putative uncharacterized protein
Gene: VNG_1339C
Organism: Halobacterium salinarium (strain ATCC 700922 / JCM 11081 / NRC-1)
Halobacterium halobium

1uniprot[Pubmed] 11016950 [Medline] 20504483
Genome sequence of Halobacterium species NRC-1.(Proc. Natl. Acad. Sci. U.S.A.) [2000]

B0R5D9_HALS3
(B0R5D9)

1e-52

212

33%

Product: Acyl-CoA synthetase
Gene: acs3
OE2912F
Organism: Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)

1uniprot[Pubmed] 18313895
Evolution in the laboratory: the genome of Halobacterium salinarum strain R1 compared to that of strain NRC-1.(Genomics) [2008]

100

B7SBA4_9BRYO
(B7SBA4)

1e-52

212

32%

Product: 4-coumarate:coenzyme A ligase 2
Gene: 4CL2
Organism: Ephemerella readeri

1uniprot[Pubmed] 18722632
Identification of a 4-coumarate:CoA ligase gene family in the moss, Physcomitrella patens.(Phytochemistry) [2008]